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SIGNIFICANT ACCOUNTING POLICIES (Tables)

12 Months Ended

Dec. 31, 2021

Schedule of Depreciation Rates for Property and Equipment

Property and equipment are stated at cost, net of accumulated depreciation. Depreciation is calculated using the straight-line method over the estimated useful lives of the assets at the following annual rates:

	%

Computers, software and related equipment	33
Laboratory equipment and office furniture	6 - 20 (mainly 20)
Leasehold improvements	Shorter of the term of the lease or useful life

Schedule of weighted-average assumptions for granted options

The Company used the following weighted-average assumptions for options granted to employees, directors and non-employees and ESPP:

		Year ended December 31,
		2021	2020	2019

Employee stock Options
Volatility		67.68%	63.17%	54.59%
Risk-free interest rate		0.77%	0.45%	1.92%
Dividend yield		0%	0%	0%
Expected life (years)		5.17	5.16	5.15

ESPP
Volatility	64.68%-69.68%		-	-
Risk-free interest rate		0.04%-0.10%	-	-
Dividend yield		0%	-	-
Expected life (years)		0.42-0.50	-	-