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SHAREHOLDERS' EQUITY (Share Option Plans) (Narrative) (Details)
$ / shares in Units, $ in Thousands
1 Months Ended 12 Months Ended
Apr. 14, 2020
shares
Oct. 10, 2018
USD ($)
$ / shares
Jun. 14, 2018
USD ($)
$ / shares
shares
Nov. 30, 2021
USD ($)
$ / shares
Mar. 16, 2020
$ / shares
shares
May 25, 2018
USD ($)
$ / shares
Dec. 31, 2021
USD ($)
$ / shares
shares
Dec. 31, 2020
USD ($)
$ / shares
shares
Dec. 31, 2019
USD ($)
$ / shares
shares
Dec. 31, 2021
₪ / shares
Dec. 31, 2020
₪ / shares
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                      
Weighted average fair value of stock options granted | $ / shares             $ 3.81 $ 7.15 $ 1.73    
Unrecognized share-based compensation expense             $ 11,926        
Unrecognized compensation cost, recognition period             3 years 7 days        
Ordinary shares, par value | ₪ / shares                   ₪ 0.01 ₪ 0.01
Ordinary shares, shares authorized | shares             200,000,000 200,000,000      
Proceeds from warrant exercised             $ 425 $ 18,325    
Equity investment             $ 12,000        
Employee Stock Purchase Plan [Member]                      
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                      
Ordinary shares reserved for issuance | shares             600,000        
Ordinary shares available for issuance | shares             482,171        
Offering period             five months        
Percentage of use of base salary to purchase ordinary shares             15.00%        
Aggregate limit of ordinary shares per calendar year | $ / shares             $ 40        
Percentage of fair market value of ordinary shares at time of offering             85.00%        
Options granted | shares             117,829        
Director [Member]                      
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                      
Aggregate intrinsic value of exercised options             $ 759 $ 21,610 979    
2000 and 2010 Share Option Plans [Member]                      
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                      
Ordinary shares reserved for issuance | shares             12,395,152        
Ordinary shares available for issuance | shares             1,133,128        
Vesting period             4 years        
Award expiration period             10 years        
Warrant [Member]                      
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                      
Ordinary shares, shares authorized | shares             3,955,696 3,955,696      
Warrants purchase to ordinary shares remain outstanding | shares             297,469        
Proceeds from warrant exercised             $ 18,750 $ 18,750      
At The Market Offering Program [Member]                      
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                      
Ordinary shares, par value | $ / shares           $ 0.01          
Proceeds from issuance of common stock           $ 25,000     $ 22,914    
Issuance of shares, net, shares | shares                 7,245,268    
Issuance expenses                 $ 781    
Agreement [Member] | Registered direct offering [Member]                      
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                      
Offering price per share | $ / shares     $ 3.95                
Proceeds from issuance of common stock     $ 19,767                
Ordinary shares, shares authorized | shares     5,316,457                
Warrants purchase to ordinary shares | shares     4,253,165                
Exercise price of warrants | $ / shares     $ 4.74                
Expiration period of warrants     5 years                
Issuance expenses     $ 1,233                
Master Clinical Agreement [Member]                      
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                      
Offering price per share | $ / shares   $ 4.95   $ 8.57333              
Proceeds from issuance of common stock   $ 2,424,243   $ 2,332,815              
Equity investment   $ 12,000   $ 20,000              
Percentage of closing price   33.00%   33.00%              
Collaborative Arrangements [Member]                      
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                      
Proceeds from issuance of common stock             7,788        
Issuance expenses             91        
Deferred participation of BMS in R&D expenses             4,121        
Collaborative Arrangements Two [Member]                      
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                      
Proceeds from issuance of common stock             14,958        
Issuance expenses             42        
Deferred participation of BMS in R&D expenses             $ 5,000        
SVB Leerink LLC and Stifel, Nicolaus & Company [Member]                      
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                      
Offering price per share | $ / shares         $ 9.00            
Issuance of shares, net, shares | shares         8,333,334   8,816,339        
Issuance expenses             $ 5,200        
Proceeds from ordinary shares in offering             $ 74,147        
SVB Leerink LLC and Stifel, Nicolaus & Company [Member] | Underwriters [Member]                      
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                      
Offering price per share | $ / shares         $ 8.46            
Issuance of shares, net, shares | shares 483,005