Consent of Independent Registered Public Accounting Firm
We consent to the incorporation by reference in the Registration Statements on Form S-8 (Nos. 333-169239, 333-204869, 333-223937, 333-240182, 333-251263) pertaining to the Employee’s share option
plans of Compugen Ltd. and Registration Statements on Form F-3 (File No. 333-240183) of our report dated February 28, 2022, with respect to the consolidated financial statements of Compugen Ltd. and the effectiveness of internal control over
financial reporting of Compugen Ltd. included in this Annual Report (Form 20-F) for the year ended December 31, 2021.
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February 28, 2022
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/s/ KOST FORER GABBAY & KASIERER
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Tel-Aviv, Israel
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A Member Firm of Ernst & Young Global
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