<SEC-DOCUMENT>0001178913-22-004226.txt : 20221202
<SEC-HEADER>0001178913-22-004226.hdr.sgml : 20221202
<ACCEPTANCE-DATETIME>20221202070012
ACCESSION NUMBER:		0001178913-22-004226
CONFORMED SUBMISSION TYPE:	6-K
PUBLIC DOCUMENT COUNT:		1
CONFORMED PERIOD OF REPORT:	20221202
FILED AS OF DATE:		20221202
DATE AS OF CHANGE:		20221202

FILER:

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			COMPUGEN LTD
		CENTRAL INDEX KEY:			0001119774
		STANDARD INDUSTRIAL CLASSIFICATION:	BIOLOGICAL PRODUCTS (NO DIAGNOSTIC SUBSTANCES) [2836]
		IRS NUMBER:				000000000
		STATE OF INCORPORATION:			L3
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		6-K
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	000-30902
		FILM NUMBER:		221440256

	BUSINESS ADDRESS:	
		STREET 1:		26 HAROKMIM STREET
		STREET 2:		BUILDING D
		CITY:			HOLON
		STATE:			L3
		ZIP:			5885849
		BUSINESS PHONE:		011-972-3-765-8585

	MAIL ADDRESS:	
		STREET 1:		26 HAROKMIM STREET
		STREET 2:		BUILDING D
		CITY:			HOLON
		STATE:			L3
		ZIP:			5885849
</SEC-HEADER>
<DOCUMENT>
<TYPE>6-K
<SEQUENCE>1
<FILENAME>zk2228843.htm
<DESCRIPTION>6-K
<TEXT>
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      <div style="text-align: center; line-height: 1.25; font-family: 'Times New Roman',Times,serif; font-size: 14pt; font-weight: bold; background-color: rgb(255, 255, 255); color: rgb(0, 0, 0); font-style: normal; font-variant: normal; text-transform: none;">SECURITIES AND EXCHANGE COMMISSION</div>
      <div style="text-align: center; line-height: 1.25; font-weight: bold;">Washington, D.C. 20549</div>
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      <div style="line-height: 1.25;"><br style="line-height: 1.25;">
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      <div style="text-align: center; line-height: 1.25; font-weight: bold;">REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16</div>
      <div style="text-align: center; line-height: 1.25; font-weight: bold;">UNDER THE SECURITIES EXCHANGE ACT OF 1934</div>
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      <div style="text-align: center; line-height: 1.25;">For the month of December 2022</div>
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      <div style="text-align: center; line-height: 1.25;">Commission File Number 000-30902</div>
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      <div style="text-align: center; line-height: 1.25; font-family: 'Times New Roman',Times,serif; font-size: 16pt; font-weight: bold; background-color: rgb(255, 255, 255); color: rgb(0, 0, 0); font-style: normal; font-variant: normal; text-transform: none;">COMPUGEN LTD.</div>
      <div style="text-align: center; line-height: 1.25;">(Translation of registrant&#8217;s name into English)</div>
      <table cellspacing="0" cellpadding="0" style="font-family: 'Times New Roman', Times, serif; font-size: 10pt; width: 100%; text-align: left; color: #000000;" id="z8f33d32c893b42eeb17fdfa33006737c">

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              <div style="text-align: center; line-height: 1.25; font-weight: bold;">26&#160;Harokmim Street</div>
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              <div style="text-align: center; line-height: 1.25; font-weight: bold;">Holon 5885849, Israel</div>
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              <div style="text-align: center; line-height: 1.25;">(Address of Principal Executive Offices)&#160;</div>
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      <div style="line-height: 1.25;">Indicate by check mark whether the registrant files or will file annual reports under cover of Form 20-F or Form 40-F:</div>
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      </div>
      <div style="text-align: center; line-height: 1.25; font-family: 'Times New Roman',Times,serif;">Form 20-F &#9745;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160; Form 40-F &#9744;</div>
      <div style="line-height: 1.25;"><br style="line-height: 1.25;">
      </div>
      <div style="line-height: 1.25;">Indicate by check mark if the registrant is submitting the Form 6-K in paper as permitted by Regulation S-T Rule 101(b)(1): &#160; &#160; &#160; &#160; &#9744;</div>
      <div style="line-height: 1.25;"><br style="line-height: 1.25;">
      </div>
      <div style="line-height: 1.25;">Indicate by check mark if the registrant is submitting the Form 6-K in paper as permitted by Regulation S-T Rule 101(b)(7): &#160; &#160; &#160; &#160; &#9744;</div>
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      <div style="text-align: center; line-height: 1.25; font-weight: bold;">Compugen Ltd.</div>
      <div style="line-height: 1.25;"><br style="line-height: 1.25;">
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      <div style="line-height: 1.25;">
        <div style="line-height: 1.25;">On November 29, 2022, Bayer AG (formerly, Bayer Pharma AG) (&#8220;<font style="font-weight: bold;">Bayer</font>&#8221;) notified Compugen Ltd. (the &#8220;<font style="font-weight: bold;">Company</font>&#8221;) that it has resolved to
          terminate, effective as of February 27, 2023, the parties&#8217; research and development collaboration and license agreement, previously effective as of August 5, 2013.&#160;</div>
        <div style="line-height: 1.25;"><br style="line-height: 1.25;">
        </div>
        <div style="line-height: 1.25;">Pursuant to the agreement, bapotulimab, an antibody targeting Compugen-discovered immune checkpoint regulator CGEN-15001T/ILDR2, was evaluated by Bayer in a Phase 1 clinical trial. Following the effective date of the
          termination, Bayer will retain the right to continue to provide patients with bapotulimab to the extent required.</div>
        <div style="line-height: 1.25;"><br style="line-height: 1.25;">
        </div>
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      <div style="line-height: 1.25;">
        <div style="line-height: 1.25;">The Company plans to execute its right to receive an exclusive license under Bayer&#8217;s intellectual property as required to allow it to continue the development and commercialization of bapotulimab, to the extent it
          will choose to do so.</div>
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      <div style="line-height: 1.25;">
        <div style="line-height: 1.25;"><br style="line-height: 1.25;">
        </div>
        <div style="line-height: 1.25;">The information contained in this Report on Form 6-K is hereby incorporated by reference into the Company&#8217;s Registration Statement on Form F-3, File No. 333-240183.</div>
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      <div style="text-align: center; line-height: 1.25; font-weight: bold;">Signatures</div>
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      <div style="line-height: 1.25;">Pursuant to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned thereunto duly authorized.</div>
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                  <div style="line-height: 1.25; font-weight: bold;">COMPUGEN LTD.</div>
                  <div style="line-height: 1.25; font-weight: bold;"> <br>
                  </div>
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                    <div style="line-height: 1.25;">Date: December 2, 2022</div>
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                  <div style="line-height: 1.25;">By:&#160;</div>
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                  <div style="line-height: 1.25;">/s/ Eran Ben Dor&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;</div>
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                  <div style="line-height: 1.25;">Eran Ben Dor</div>
                  <div style="line-height: 1.25;">General Counsel</div>
                </td>
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