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Restructuring Plan - Summary of restructuring costs in statement of operations (Details) - USD ($) $ in Thousands | 3 Months Ended | 9 Months Ended
--- | --- | ---
Sep. 30, 2023 | Sep. 30, 2022 | Sep. 30, 2023 | Sep. 30, 2022
Restructuring Cost and Reserve [Line Items] |  |  |  |
General and Administrative Expense | $ 2,125 | $ 4,490 | $ 22,869 | $ 14,294
Research and Development Expense | 2,876 | $ 4,258 | 12,284 | $ 21,287
ROU Asset Impairment [Member] |  |  |  |
Restructuring Cost and Reserve [Line Items] |  |  |  |
General and Administrative Expense | 0 |  | 180 |
Research and Development Expense |  |  | 0 |
Total Restructuring Costs | 0 |  | 180 |
Severance and Benefits Costs Member |  |  |  |
Restructuring Cost and Reserve [Line Items] |  |  |  |
General and Administrative Expense | 189 |  | 6,025 |
Research and Development Expense |  |  | 1,342 |
Total Restructuring Costs | 189 |  | 7,367 |
Stock-based Compensation Member |  |  |  |
Restructuring Cost and Reserve [Line Items] |  |  |  |
General and Administrative Expense | 33 |  | 8,707 |
Research and Development Expense |  |  | 488 |
Total Restructuring Costs | 33 |  | 9,195 |
Total Restructuring Cost Recorded [Member] |  |  |  |
Restructuring Cost and Reserve [Line Items] |  |  |  |
General and Administrative Expense | 222 |  | 14,912 |
Research and Development Expense |  |  | 1,830 |
Total Restructuring Costs | $ 222 |  | $ 16,742 |

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- Definition The aggregate total of expenses of managing and administering the affairs of an entity, including affiliates of the reporting entity, which are not directly or indirectly associated with the manufacture, sale or creation of a product or product line. + References Reference 1: http://www.xbrl.org/2003/role/disclosureRef -Topic 946 -SubTopic 220 -Name Accounting Standards Codification -Section S99 -Paragraph 1 -Subparagraph (SX 210.6-07(2)(a)) -Publisher FASB -URI https://asc.fasb.org//1943274/2147483575/946-220-S99-1 Reference 2: http://fasb.org/us-gaap/role/ref/legacyRef -Topic 220 -SubTopic 10 -Name Accounting Standards Codification -Section S99 -Paragraph 2 -Subparagraph (SX 210.5-03.4) -Publisher FASB -URI https://asc.fasb.org//1943274/2147483621/220-10-S99-2 + Details
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