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Restructuring Plan - Summary of restructuring costs in statement of operations (Details) - USD ($)
$ in Thousands
 3 Months Ended 9 Months Ended
Sep. 30, 2023
Sep. 30, 2022
Sep. 30, 2023
Sep. 30, 2022
Restructuring Cost and Reserve [Line Items]        
General and Administrative Expense $ 2,125 $ 4,490 $ 22,869 $ 14,294
Research and Development Expense 2,876 $ 4,258 12,284 $ 21,287
ROU Asset Impairment [Member]        
Restructuring Cost and Reserve [Line Items]        
General and Administrative Expense 0   180  
Research and Development Expense     0  
Total Restructuring Costs 0   180  
Severance and Benefits Costs Member        
Restructuring Cost and Reserve [Line Items]        
General and Administrative Expense 189   6,025  
Research and Development Expense     1,342  
Total Restructuring Costs 189   7,367  
Stock-based Compensation Member        
Restructuring Cost and Reserve [Line Items]        
General and Administrative Expense 33   8,707  
Research and Development Expense     488  
Total Restructuring Costs 33   9,195  
Total Restructuring Cost Recorded [Member]        
Restructuring Cost and Reserve [Line Items]        
General and Administrative Expense 222   14,912  
Research and Development Expense     1,830  
Total Restructuring Costs $ 222   $ 16,742