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v3.26.1

Segments (Tables) | 6 Months Ended
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Jun. 30, 2026
Segment Reporting [Abstract] |
Schedule of Forth Disaggregated Research and Development Expenses | In addition to the significant expense categories included within net loss presented on the unaudited condensed consolidated statements of operations and comprehensive loss, the following table sets forth disaggregated research and development expenses (in thousands):
|  | Three Months Ended June 30, |  |  | Six Months Ended June 30, |
|  | 2026 |  |  | 2025 |  |  | 2026 |  |  | 2025 |
Direct research and development expenses: |  |  |  |  |  |  |  |  |  |  |  |
Budoprutug |  | $ | 5,288 |  |  | $ | 4,521 |  |  | $ | 10,651 |  |  | $ | 10,662 |
CLYM116 1 |  |  | 1,511 |  |  |  | 145 |  |  |  | 2,704 |  |  |  | 9,265 |
Legacy programs 2 |  |  | 7 |  |  |  | 31 |  |  |  | 29 |  |  |  | 73 |
Unallocated research and development expenses: |  |  |  |  |  |  |  |  |  |  |  |
Personnel-related (including stock-based compensation) |  |  | 2,346 |  |  |  | 1,452 |  |  |  | 4,699 |  |  |  | 3,209 |
Other research and development expenses |  |  | 562 |  |  |  | 426 |  |  |  | 1,004 |  |  |  | 693 |
Total research and development expenses |  | $ | 9,714 |  |  | $ | 6,575 |  |  | $ | 19,087 |  |  | $ | 23,902 |
1 Includes the upfront payment and the associated direct transaction costs incurred in connection with the Mabworks Agree ment for the six months ended June 30, 2025. 2 Includes direct expenses related to the Company’s legacy product candidates ETX-123 and ETX-155.

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