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Commitments and Contingencies - Additional Information (Details) $ in Thousands, € in Millions, £ in Millions |  | 1 Months Ended | 3 Months Ended | 6 Months Ended |  |  |
--- | --- | --- | --- | --- | --- | --- | ---
Jan. 08, 2025 USD ($) | May 31, 2026 USD ($) | Jun. 30, 2026 USD ($) | Jun. 30, 2025 USD ($) | Mar. 31, 2025 USD ($) | Jun. 30, 2026 USD ($) | Jun. 30, 2025 USD ($) | Jun. 30, 2026 GBP (£) | Jan. 31, 2024 GBP (£) | Feb. 28, 2021 EUR (€)
Gain Contingencies [Line Items] |  |  |  |  |  |  |  |  |  |
Extended lease term |  | 3 years |  |  |  |  |  |  |  |
Annual Base Rent |  | $ 600 |  |  |  |  |  |  |  |
Option to extend the lease |  | no |  |  |  |  |  |  |  |
Increase to operating lease right-of-use assets and operating lease liabilities |  | $ 1,100 |  |  |  |  |  |  |  |
Decrease in operating lease liabilities and corresponding right-of-use asset |  | $ 300 |  |  |  |  |  |  |  |
Research and development Expense |  |  | $ 9,714 | $ 6,575 |  | $ 19,087 | $ 23,902 |  |  |
Increase decrease in operating lease liability |  |  |  |  |  | 5 | (109) |  |  |
ProBioGen Agreement [Member] | Manufacturing Services [Member] |  |  |  |  |  |  |  |  |  |
Gain Contingencies [Line Items] |  |  |  |  |  |  |  |  |  |
Milestone Payment, Amount Reduced |  |  | 1,200 |  |  | 1,200 |  |  |  | € 1.1
Mabworks Agreement [Member] |  |  |  |  |  |  |  |  |  |
Gain Contingencies [Line Items] |  |  |  |  |  |  |  |  |  |
Upfront Payment Paid | $ 9,000 |  |  |  |  |  |  |  |  |
Maximum [Member] | ProBioGen Agreement [Member] | Sales Milestones [Member] |  |  |  |  |  |  |  |  |  |
Gain Contingencies [Line Items] |  |  |  |  |  |  |  |  |  |
Milestone Payments |  |  | 8,000 |  |  | 8,000 |  |  |  | 7.0
Development Regulatory and Commercial Milestones [Member] | Maximum [Member] | Acelyrin Asset Purchase Agreement [Member] |  |  |  |  |  |  |  |  |  |
Gain Contingencies [Line Items] |  |  |  |  |  |  |  |  |  |
Milestone Payments |  |  | 157,500 |  |  | 157,500 |  |  |  |
Development and Regulatory Milestones [Member] | Mabworks Agreement [Member] |  |  |  |  |  |  |  |  |  |
Gain Contingencies [Line Items] |  |  |  |  |  |  |  |  |  |
Milestone Payments | 30,000 |  |  |  |  |  |  |  |  |
Development Regulatory Commercial and Sales Milestones Member] | Maximum [Member] | CRH Agreement [Member] |  |  |  |  |  |  |  |  |  |
Gain Contingencies [Line Items] |  |  |  |  |  |  |  |  |  |
Milestone Payments | £ |  |  |  |  |  |  |  | £ 141.4 | £ 106.8 |
Development Manufacturing and Commercial [Member] | Maximum [Member] | ProBioGen Agreement [Member] |  |  |  |  |  |  |  |  |  |
Gain Contingencies [Line Items] |  |  |  |  |  |  |  |  |  |
Milestone Payments |  |  | 11,400 |  |  | 11,400 |  |  |  | € 10.0
Commercial Milestones [Member] | Mabworks Agreement [Member] |  |  |  |  |  |  |  |  |  |
Gain Contingencies [Line Items] |  |  |  |  |  |  |  |  |  |
Milestone Payments | $ 832,000 |  |  |  |  |  |  |  |  |
Milestone [Member] | ProBioGen Agreement [Member] |  |  |  |  |  |  |  |  |  |
Gain Contingencies [Line Items] |  |  |  |  |  |  |  |  |  |
Research and development Expense |  |  | 0 | $ 800 |  | 0 | $ 800 |  |  |
Milestone [Member] | Mabworks Agreement [Member] |  |  |  |  |  |  |  |  |  |
Gain Contingencies [Line Items] |  |  |  |  |  |  |  |  |  |
Research and development Expense |  |  | $ 0 |  |  | $ 0 |  |  |  |
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Gain Contingencies [Line Items] |  |  |  |  |  |  |  |  |  |
Upfront Payment Paid |  |  |  |  | $ 9,000 |  |  |  |  |

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