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<SEC-DOCUMENT>0001157523-10-004949.txt : 20100810
<SEC-HEADER>0001157523-10-004949.hdr.sgml : 20100810
<ACCEPTANCE-DATETIME>20100809185210
ACCESSION NUMBER:		0001157523-10-004949
CONFORMED SUBMISSION TYPE:	8-K
PUBLIC DOCUMENT COUNT:		2
CONFORMED PERIOD OF REPORT:	20100809
ITEM INFORMATION:		Results of Operations and Financial Condition
ITEM INFORMATION:		Financial Statements and Exhibits
FILED AS OF DATE:		20100810
DATE AS OF CHANGE:		20100809

FILER:

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			ANIKA THERAPEUTICS INC
		CENTRAL INDEX KEY:			0000898437
		STANDARD INDUSTRIAL CLASSIFICATION:	SURGICAL & MEDICAL INSTRUMENTS & APPARATUS [3841]
		IRS NUMBER:				043145961
		STATE OF INCORPORATION:			MA
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		8-K
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	001-14027
		FILM NUMBER:		101003016

	BUSINESS ADDRESS:	
		STREET 1:		236 WEST CUMMINGS PARK
		CITY:			WOBURN
		STATE:			MA
		ZIP:			01801
		BUSINESS PHONE:		6179326616

	MAIL ADDRESS:	
		STREET 1:		236 WEST CUMMINGS PARK
		CITY:			WOBURN
		STATE:			MA
		ZIP:			01801

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	ANIKA RESEARCH INC
		DATE OF NAME CHANGE:	19930309
</SEC-HEADER>
<DOCUMENT>
<TYPE>8-K
<SEQUENCE>1
<FILENAME>a6390973.htm
<DESCRIPTION>ANIKA THERAPEUTICS, INC. 8-K
<TEXT>
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    <p style="text-align: center">
      <font style="font-family: Times New Roman; font-size: 12pt">UNITED STATES</font><font style="font-family: Times New Roman; font-size: 12pt"><br style="font-family: Times New Roman; font-size: 12pt"></font><font style="font-family: Times New Roman; font-size: 12pt">SECURITIES
      AND EXCHANGE COMMISSION</font>
    </p>
    <p style="text-align: center">
      <font style="font-size: 10pt">Washington, D.C. 20549</font>
    </p>
    <p style="text-align: center">
      <font style="font-family: Times New Roman; font-size: 12pt">FORM 8-K</font><br>
    </p>
    <p style="text-align: center">
      <font style="font-size: 12pt">CURRENT REPORT</font><font style="font-size: 12pt"><br style="font-size: 12pt"></font><font style="font-size: 12pt">PURSUANT
      TO SECTION 13 OR 15(d)</font><br><font style="font-size: 12pt">OF THE
      SECURITIES EXCHANGE ACT OF 1934</font>
    </p>
    <p style="text-align: center">
      <font style="font-family: Times New Roman; font-size: 11pt">Date of
      Report (Date of earliest event reported): August 9, 2010</font>
    </p>
    <p style="text-align: center">
      <font style="font-size: 12pt">Anika Therapeutics, Inc.</font><br><i>(Exact
      name of registrant as specified in its charter)</i>
    </p>
    <hr style="height: 1.0 pt; color: #000000; text-align: center; width: 20%">


    <p style="text-align: center">

    </p>
    <div style="text-align:left">
    <table cellspacing="0" style="margin-bottom: 10.0px; font-size: 10pt; font-family: Times New Roman; width: 100%">
      <tr>
        <td valign="bottom" style="padding-left: 0.0px; text-align: center; width: 33%">
          <p style="margin-bottom: 0px; margin-top: 0px">
            Massachusetts
          </p>
        </td>
        <td valign="bottom" style="padding-left: 0.0px; white-space: nowrap; text-align: center; width: 34%; padding-right: 0.0px">
          <p style="margin-bottom: 0px; margin-top: 0px">
            000-21326
          </p>
        </td>
        <td valign="bottom" style="padding-left: 0.0px; white-space: nowrap; text-align: center; width: 33%; padding-right: 0.0px">
          <p style="margin-bottom: 0px; margin-top: 0px">
            04-3145961
          </p>
        </td>
      </tr>
      <tr>
        <td valign="top" style="padding-left: 0.0px; text-align: center; width: 33%">
          <p style="margin-bottom: 0px; margin-top: 0px">
            <i>(State or other jurisdiction of<br>incorporation or
            organization)</i>
          </p>
        </td>
        <td valign="top" style="padding-left: 0.0px; text-align: center; width: 34%">
          <p style="margin-bottom: 0px; margin-top: 0px">
            <i>Commission file number</i>
          </p>
        </td>
        <td valign="top" style="padding-left: 0.0px; text-align: center; width: 33%">
          <p style="margin-bottom: 0px; margin-top: 0px">
            <i>(I.R.S. Employer<br>Identification No.)</i>
          </p>
        </td>
      </tr>
    </table>
    </div>
    <p style="text-align: center">
      32 Wiggins Avenue, Bedford, MA 01730<br><i>(Address of principal
      executive offices) (Zip code)</i>
    </p>
    <p style="text-align: center">
      <i>Registrant&#8217;s telephone number, including area code:&#160;&#160;&#160;</i>781-457-9000
    </p>
    <p style="text-align: center">
      <br>
      <i>(Former name or former address, if changed since last report)</i>
    </p>
    <hr style="height: 1.0 pt; color: #000000; text-align: center; width: 20%">


    <p style="text-align: center">

    </p>
    <p>
      <font style="font-family: Times New Roman; font-size: 10pt">Check the
      appropriate box below if the Form 8-K filing is intended to
      simultaneously satisfy the filing obligation of the registrant under any
      of the following provisions:</font>
    </p>
    <p>
      <font style="font-family: Arial Unicode MS; font-size: 10pt">&#8414;</font>
      <font style="font-family: Times New Roman; font-size: 10pt">Written
      communications pursuant to Rule 425 under the Securities Act (17 CFR
      230.425)</font><br><font style="font-family: Arial Unicode MS; font-size: 10pt">&#8414;</font>
      <font style="font-family: Times New Roman; font-size: 10pt">Soliciting
      material pursuant to Rule 14a-12 under the Exchange Act (17 CFR
      240.14a-12)</font><br><font style="font-family: Arial Unicode MS; font-size: 10pt">&#8414;</font>
      <font style="font-family: Times New Roman; font-size: 10pt">Pre-commencement
      communications pursuant to Rule 14d-2(b) under the Exchange Act (17 CFR
      240.14d-2(b))</font><br><font style="font-family: Arial Unicode MS; font-size: 10pt">&#8414;</font>
      <font style="font-family: Times New Roman; font-size: 10pt">Pre-commencement
      communications pursuant to Rule 13e-4(c) under the Exchange Act (17 CFR
      240.13e-4(c))</font><br><br><br>
    </p>
    <div style="margin-bottom: 10pt; text-indent: 0pt; margin-left: 0pt; width: 100%; margin-right: 0pt">
      <div>
        <div style="text-align: left">

        </div>
      </div>
      <div style="page-break-after: always">
        <div style="text-align: center">

        </div>
        <div style="text-align: center">
          <hr style="height: 1.5pt; color: black">

        </div>
      </div>
      <div>
        <div style="text-align: right">

        </div>
      </div>
    </div>
    <p>

    </p>
    <p style="text-align: center">
      <b>Section 2--Financial Information</b>
    </p>
    <p>

    </p>
    <p>
      Item 2.02.&#160;&#160;Results of Operations and Financial Condition.
    </p>
    <p>
      The following information, including the exhibit attached hereto, is
      intended to be furnished and shall not be deemed &quot;filed&quot; for purposes of
      Section 18 of the Securities Exchange Act of 1934 (the &quot;Exchange Act&quot;)
      or otherwise subject to the liabilities of that section, nor shall it be
      deemed incorporated by reference in any filing under the Securities Act
      of 1933 or the Exchange Act, except as expressly set forth by specific
      reference in such filing.
    </p>
    <p>
      On August 9, 2010, Anika Therapeutics, Inc. issued a press release
      announcing its financial results for the second quarter ended June 30,
      2010.&#160;&#160;The full text of the press release is furnished as Exhibit 99.1
      hereto and is incorporated herein by reference.
    </p>
    <p>

    </p>
    <p style="text-align: center">
      <b>Section 9--Financial Statements and Exhibits</b>
    </p>
    <p>

    </p>
    <p style="white-space: nowrap">
      Item 9.01.&#160;&#160;Financial Statements and Exhibits.
    </p>
    <p>
      (d)&#160;&#160;Exhibits.
    </p>
    <p>
      99.1&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;Press Release of Anika Therapeutics, Inc. dated August 9,
      2010.<br><br><br><br><br><br>
    </p>
    <p style="white-space: nowrap">

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    <p style="text-align: center">
      [Remainder of page left blank intentionally]
    </p>
    <p>

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        <div style="text-align: left">

        </div>
      </div>
      <div style="page-break-after: always">
        <div style="text-align: center">

        </div>
        <div style="text-align: center">
          <hr style="height: 1.5pt; color: black">

        </div>
      </div>
      <div>
        <div style="text-align: right">

        </div>
      </div>
    </div>
    <p>

    </p>
    <p style="text-align: center">
      <font style="font-family: Times New Roman; font-size: 10pt">SIGNATURE</font><br>
    </p>
    <p>
      Pursuant to the requirements of the Securities Exchange Act of 1934, the
      registrant has duly caused this report to be filed on its behalf by the
      undersigned hereunto duly authorized.
    </p>
    <p>

    </p>
    <div style="text-align:left">
    <table cellspacing="0" style="margin-bottom: 10.0px; font-size: 10pt; font-family: Times New Roman; width: 100%">
      <tr>
        <td style="width: 6%">

        </td>
        <td style="width: 44%">

        </td>
        <td valign="top" colspan="3" style="padding-left: 0.0px; text-align: left">
          <p style="margin-bottom: 0px; margin-top: 0px">
            Anika Therapeutics, Inc.
          </p>
        </td>
        <td style="width: 13%">

        </td>
      </tr>
      <tr>
        <td style="width: 6%">

        </td>
        <td style="width: 44%">

        </td>
        <td colspan="3">

        </td>
        <td style="width: 13%">
          &#160;
        </td>
      </tr>
      <tr>
        <td style="width: 6%">

        </td>
        <td style="width: 44%">

        </td>
        <td valign="top" colspan="3" style="padding-left: 0.0px; text-align: left">
          <p style="margin-bottom: 0px; margin-top: 0px">
            &#160;
          </p>
        </td>
        <td style="width: 13%">

        </td>
      </tr>
      <tr>
        <td valign="top" style="padding-left: 0.0px; padding-bottom: 2.0px; text-align: left; width: 6%">
          <p style="margin-bottom: 0px; margin-top: 0px">
            Dated:
          </p>
        </td>
        <td valign="top" style="padding-left: 0.0px; padding-bottom: 2.0px; text-align: left; width: 44%">
          <p style="margin-bottom: 0px; margin-top: 0px">
            August 9, 2010
          </p>
        </td>
        <td valign="top" style="padding-left: 0.0px; padding-bottom: 2.0px; text-align: left; width: 3%">
          By:
        </td>
        <td style="border-bottom: solid black 1.0pt; width: 4%">
          &#160;
        </td>
        <td valign="top" style="border-bottom: solid black 1.0pt; padding-left: 0.0px; text-align: left; width: 30%">
          <p style="margin-bottom: 0px; margin-top: 0px">
            /s/ Kevin W. Quinlan
          </p>
        </td>
        <td style="width: 13%">

        </td>
      </tr>
      <tr>
        <td style="width: 6%">

        </td>
        <td style="width: 44%">

        </td>
        <td valign="top" style="padding-left: 0.0px; text-align: left; width: 3%">
          <p style="margin-bottom: 0px; margin-top: 0px">
            &#160;
          </p>
        </td>
        <td style="width: 4%">
          &#160;
        </td>
        <td valign="top" style="padding-left: 0.0px; text-align: left; width: 30%">
          <p style="margin-bottom: 0px; margin-top: 0px">
            Kevin W. Quinlan
          </p>
        </td>
        <td style="width: 13%">

        </td>
      </tr>
      <tr>
        <td style="width: 6%">

        </td>
        <td style="width: 44%">

        </td>
        <td valign="top" style="padding-left: 0.0px; text-align: left; width: 3%">
          <p style="margin-bottom: 0px; margin-top: 0px">
            &#160;
          </p>
        </td>
        <td style="width: 4%">

        </td>
        <td valign="top" style="padding-left: 0.0px; text-align: left; width: 30%">
          <p style="margin-bottom: 0px; margin-top: 0px">
            Chief Financial Officer
          </p>
        </td>
        <td style="width: 13%">

        </td>
      </tr>
      <tr>
        <td style="width: 6%">

        </td>
        <td style="width: 44%">

        </td>
        <td style="width: 3%">

        </td>
        <td style="width: 4%">

        </td>
        <td valign="top" style="padding-left: 0.0px; text-align: left; width: 30%">
          <p style="margin-bottom: 0px; margin-top: 0px">
            &#160;
          </p>
        </td>
        <td style="width: 13%">

        </td>
      </tr>
    </table>
    </div>
    <p>

    </p>
    <div style="margin-bottom: 10pt; text-indent: 0pt; margin-left: 0pt; width: 100%; margin-right: 0pt">
      <div>
        <div style="text-align: left">

        </div>
      </div>
      <div style="page-break-after: always">
        <div style="text-align: center">

        </div>
        <div style="text-align: center">
          <hr style="height: 1.5pt; color: black">

        </div>
      </div>
      <div>
        <div style="text-align: right">

        </div>
      </div>
    </div>
    <p>

    </p>
    <p style="text-align: center">
      Exhibit Index
    </p>
    <div style="text-align:left">
    <table cellspacing="0" style="margin-bottom: 10.0px; font-size: 10pt; font-family: Times New Roman; width: 100%">
      <tr>
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          99.1
        </td>
        <td valign="top" style="padding-left: 0.0px; text-align: left; width: 88%">
          <p style="margin-bottom: 0px; margin-top: 0px">
            Press Release of Anika Therapeutics, Inc. dated August 9, 2010.
          </p>
        </td>
      </tr>
    </table>
    </div>
    <p>

    </p>
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</DOCUMENT>
<DOCUMENT>
<TYPE>EX-99.1
<SEQUENCE>2
<FILENAME>a6390973ex99_1.htm
<DESCRIPTION>EXHIBIT 99.1
<TEXT>
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    <title></title>
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    <p style="text-align: right">
      <b>Exhibit 99.1</b>
    </p>
    <p style="text-align: center">
      <font style="font-family: Times New Roman; font-size: 12pt"><b>Anika
      Therapeutics Reports 52% Total Revenue Growth in Second Quarter 2010</b></font>
    </p>
    <p style="text-align: center">
      <i><font style="font-family: Times New Roman; font-size: 12pt"><b>ORTHOVISC</b></font><b><sup><font style="font-family: Times New Roman; font-size: 12pt">&#174;
      </font></sup><font style="font-family: Times New Roman; font-size: 12pt">Sales
      Drive 24% Organic Growth</font></b></i>
    </p>
    <p style="text-align: center">
      <i><font style="font-family: Times New Roman; font-size: 12pt"><b>Company
      Reports Progress on FAB Integration</b></font></i>
    </p>
    <p>
      BEDFORD, Mass.--(BUSINESS WIRE)--August 9, 2010--Anika Therapeutics,
      Inc. (Nasdaq: ANIK), a leader in products for tissue protection,
      healing, and repair, based on hyaluronic acid (&#8220;HA&#8221;) technology, today
      reported financial results for the quarter ended June 30, 2010.
    </p>
    <p>
      <b>Key Highlights</b>
    </p>
    <ul>
      <li style="margin-bottom: 10.0px">
        Total revenue and product revenue grew 52% and 56% respectively
      </li>
      <li style="margin-bottom: 10.0px">
        Progress on FAB integration as FAB products perform well in quarter
      </li>
      <li style="margin-bottom: 10.0px">
        Orthobiologics revenue rose 38%, driven by strong global sales of
        ORTHOVISC<sup><i><b>&#174;</b></i></sup>
      </li>
    </ul>
    <p>
      <b>Revenue</b>
    </p>
    <p>
      Anika&#8217;s product revenue increased 56% to $13.7 million for the second
      quarter of 2010, from $8.8 million in the second quarter of 2009.
      Excluding revenue from Fidia Advanced Biopolymers, s.r.l. (&#8220;FAB&#8221;), which
      was acquired by Anika late in the fourth quarter of 2009, product
      revenue increased 24% from 2009&#8217;s second quarter. This growth was
      primarily due to continued strong sales of the Company&#8217;s ORTHOVISC
      product line in U.S. and international markets.
    </p>
    <p>
      Total revenue for the second quarter of 2010 grew 52% to $14.5 million,
      from $9.5 million in the second quarter last year.
    </p>
    <p>
      <b>Product Gross Margin</b>
    </p>
    <p>
      Product gross margin for the second quarter of 2010 was 57%, compared
      with 62% in last year&#8217;s second quarter. The decrease in product gross
      margin largely reflected the addition of FAB products into Anika&#8217;s
      overall product mix and increased inventory reserves of $267,000.
    </p>
    <p>
      <b>Operating Expenses</b>
    </p>
    <p>
      Research and development expenses for the second quarter of 2010
      decreased to $1.8 million from $2.3 million in the second quarter of
      2009. This reflected a decline in R&amp;D spending due to the completion of
      Anika&#8217;s U.S. MONOVISC&#8482; clinical trial in the third quarter of 2009,
      partially offset by the inclusion of FAB R&amp;D expenses.
    </p>
    <div style="margin-bottom: 10pt; text-indent: 0pt; margin-left: 0pt; width: 100%; margin-right: 0pt">
      <div>
        <div style="text-align: left">

        </div>
      </div>
      <div style="page-break-after: always">
        <div style="text-align: center">

        </div>
        <div style="text-align: center">
          <hr style="height: 1.5pt; color: black">

        </div>
      </div>
      <div>
        <div style="text-align: right">

        </div>
      </div>
    </div>
    <p>
      Selling, general and administrative expenses for the second quarter of
      2010 increased to $5.0 million from $2.7 million in the same quarter of
      2009, primarily driven by the inclusion of SG&amp;A costs at FAB,
      integration costs, and increased reserves of $270,000 related to Coapt
      Systems accounts receivable.
    </p>
    <p>
      <b>Net Income</b>
    </p>
    <p>
      Net income for the second quarter of 2010 increased 12% to $1.1 million,
      compared with $956,000 for the same period last year. Earnings per share
      for the second quarter was $0.08 per diluted share for both 2010 and
      2009. The comparison with the 2009 period was negatively impacted by the
      dilutive effect of the FAB acquisition.
    </p>
    <p>
      <b>Cash and Cash Equivalents</b>
    </p>
    <p>
      Anika&#8217;s cash and cash equivalents at June 30, 2010 were $23.6 million,
      compared with $24.4 million on December 31, 2009.
    </p>
    <p>
      <b>Litigation and Other Legal Matters</b>
    </p>
    <p>
      On July 7, 2010, Genzyme Corporation filed a complaint against the
      Company in the United States District Court for the District of
      Massachusetts seeking unspecified damages and equitable relief. The
      complaint alleges that the Company has infringed U.S. Patent No.
      5,143,724 by manufacturing MONOVISC in the United States for sale
      outside the United States and will infringe U.S. Patent Nos. 5,143,724
      and 5,399,351&#160;if the Company begins manufacture and sale of MONOVISC for
      sale in the United States. The Company believes that neither MONOVISC,
      nor its manufacture, does or will infringe any valid and enforceable
      claim of the asserted patents.
    </p>
    <p>
      The Trustee in Bankruptcy of Artes Medical, Inc. (&quot;Artes&quot;) asked the
      Company to pay $359,768 to the Trustee, representing the total amount of
      three payments received by the Company from Artes within the 90 days
      prior to the filing of Artes' liquidating bankruptcy case under Chapter
      7 of the United States Bankruptcy Code. The Trustee asserts that the
      payments are recoverable as preferences under the Bankruptcy Code. The
      Company believes that the payments either do not meet the legal
      requirements of avoidable preferences or are subject to one or more
      exceptions to the Trustee's powers to recover preferences and recently
      so advised the Trustee.
    </p>
    <p>
      Coapt Systems, Inc., the Company's distributor for its HYDRELLE product,
      made a general assignment for the benefit of creditors and an Assignee
      began the liquidation of Coapt's assets. The Company's Distribution
      Agreement with Coapt has been terminated, and the Company plans to
      directly distribute HYDRELLE in the interim while it determines its
      worldwide strategy for this product franchise.
    </p>
    <p>
      <b>Management Commentary</b>
    </p>
    <p>
      &#8220;We made good progress executing on our key goals and driving revenue
      growth during the second quarter,&#8221; said Charles H. Sherwood, Ph.D.,
      president and chief executive officer. &#8220;Our total revenue increased by
      52% year-over-year, while product revenue grew 56%. Organic revenue was
      up 24% from the second quarter of 2009, driven by strong domestic and
      international sales of ORTHOVISC. Domestic ORTHOVISC sales were up 31%
      year-over-year, while international ORTHOVISC sales increased 18% during
      the same period.&#8221;
    </p>
    <div style="margin-bottom: 10pt; text-indent: 0pt; margin-left: 0pt; width: 100%; margin-right: 0pt">
      <div>
        <div style="text-align: left">

        </div>
      </div>
      <div style="page-break-after: always">
        <div style="text-align: center">

        </div>
        <div style="text-align: center">
          <hr style="height: 1.5pt; color: black">

        </div>
      </div>
      <div>
        <div style="text-align: right">

        </div>
      </div>
    </div>
    <p>
      &#8220;Our second-quarter net income grew 12%, tempered by the dilutive effect
      of the FAB acquisition,&#8221; said Sherwood. &#8220;One of our key goals for the
      year is to reduce FAB&#8217;s operating loss, and we made progress on that
      goal during the quarter. At the same time, we made progress during the
      quarter in generating further cost synergies through the integration of
      FAB&#8217;s operations with those of Anika. We completed the integration of
      the Anika and FAB research and development functions, implemented
      organizational changes at FAB, and began installing a new network and
      ERP system that will enable FAB and Anika to operate more effectively.&#8221;
    </p>
    <p>
      Sherwood continued, &#8220;on the regulatory front, during the quarter, in a
      meeting with the FDA on Anika&#8217;s PMA for our single-injection
      osteoarthritis product MONOVISC, the FDA requested additional
      statistical analyses. We expect to submit the additional data requested
      and responses to the FDA&#8217;s questions in September. This lengthens our
      approval process, and we currently believe will delay our timeline for
      launching MONOVISC in the U.S. market into 2011. We are also working on
      510(K) applications for a number of FAB products, and anticipate the
      first approval by year-end 2010 with the other approvals to follow in
      early 2011.&#8221;
    </p>
    <p>
      &#8220;We continue to execute successfully on our strategic goals and produce
      solid financial results, both on a consolidated and organic basis,&#8221; said
      Sherwood. &#8220;We are clearly advancing toward our vision to provide
      innovative therapeutic products which we believe will expand Anika&#8217;s
      opportunities and position us for earnings growth.&#8221;
    </p>
    <p>
      <b>Conference Call Information</b>
    </p>
    <p>
      Anika will hold a conference call to discuss its financial results,
      business highlights and outlook tomorrow, Tuesday, August 10, 2010 at
      9:00 a.m. ET. In addition, the Company will answer questions concerning
      business and financial developments and trends, and other business and
      financial matters affecting the Company, some of the responses to which
      may contain information that has not been previously disclosed.
    </p>
    <p>
      To listen to the conference call, 866-700-5192 (International callers
      dial 617-213-8833) and use the passcode 60589047. Please call
      approximately 10 minutes before the starting time and reference Anika
      Therapeutics. In addition, the conference call will be available to
      interested parties through a live audio webcast in the &#8220;Investor
      Relations&#8221; section of the Anika Therapeutics website, <u>www.anikatherapeutics.com</u>.
      An accompanying slideshow presentation also can be accessed via the
      Anika Therapeutics website. The call will be archived and accessible on
      the same website shortly after the conclusion of the call.
    </p>
    <p>
      <b>About Anika Therapeutics, Inc.</b>
    </p>
    <p>
      Headquartered in Bedford, Mass., Anika Therapeutics, Inc. develops,
      manufactures and commercializes therapeutic products for tissue
      protection, healing, and repair. These products are based on hyaluronic
      acid (HA), a naturally occurring, biocompatible polymer found throughout
      the body. Anika&#8217;s products range from orthopedic/joint health solutions
      led by ORTHOVISC<sup>&#174;</sup>, a treatment for osteoarthritis of the
      knee; to surgical aids in the ophthalmic and anti-adhesion fields. The
      company also offers aesthetic dermal fillers for the correction of
      facial wrinkles. Anika&#8217;s Italian subsidiary, Fidia Advanced Biopolymers,
      S.r.l (FAB), provides complementary HA products in orthopedic/joint
      health and anti-adhesion, as well as therapeutics in new areas such as
      advanced wound treatment and ear, nose and throat care. FAB&#8217;s
      regenerative tissue technology advances Anika&#8217;s vision to offer
      therapeutic products that go beyond pain relief to protect and restore
      damaged tissue.
    </p>
    <div style="margin-bottom: 10pt; text-indent: 0pt; margin-left: 0pt; width: 100%; margin-right: 0pt">
      <div>
        <div style="text-align: left">

        </div>
      </div>
      <div style="page-break-after: always">
        <div style="text-align: center">

        </div>
        <div style="text-align: center">
          <hr style="height: 1.5pt; color: black">

        </div>
      </div>
      <div>
        <div style="text-align: right">

        </div>
      </div>
    </div>
    <p>
      <i>The statements made in this press release which are not statements of
      historical fact are forward-looking statements within the meaning of
      Section 27A of the Securities Act of 1933 and Section 21E of the
      Securities Exchange Act of 1934, including, without limitation,
      statements that may be identified by words such as &quot;expectations,&quot;
      &quot;remains,&quot; &quot;focus,&quot; &quot;expected,&quot; &quot;prospective,&quot; &quot;expanding,&quot; &quot;building,&quot;
      &quot;continue,&quot; &quot;progress,&quot; &#8220;plan,&#8221; &quot;efforts,&quot; &quot;hope,&quot; &quot;believe,&quot;
      &quot;objectives,&quot; &quot;opportunities,&quot; &quot;will,&quot; &quot;seek,&quot; &#8220;expect&#8221; and other
      expressions which are predictions of or indicate future events and trends</i>
      <i>do not constitute historical matters and identify forward-looking
      statements.</i> <i>These statements also include those relating to: (i)
      Anika&#8217;s plans to directly distribute HYDRELLE while it determines its
      worldwide strategy for its aesthetic product franchise, (ii) the
      expectation that Anika will significantly reduce FAB&#8217;s operating loss,
      (iii) the expectation that the integration of FAB&#8217;s operations with
      those of Anika will generate further cost synergies, (iv) the
      expectation that installation of a new network and ERP system will
      enable FAB and Anika to operate more effectively, (v) the submission of
      responses to FDA questions in September 2010, (vi) the expectation that
      MONOVISC will be commercially launched into the U.S. market in 2011;
      (vii) the expectation of receiving the first 510(K) approval for a FAB
      product by the end of 2010, with additional approvals in the first
      quarter of 2011, and (viii) the expectation that Anika is positioned for
      earnings growth.</i> <i>These statements are based upon the current
      beliefs and expectations of the Company's management and are subject to
      significant risks, uncertainties and other factors.</i> <i>The Company's
      actual results could differ materially from any anticipated future
      results, performance or achievements described in the forward-looking
      statements as a result of a number of factors including: (i) the
      Company&#8217;s ability to effectively sell Hydrelle; (ii) the Company's
      ability to successfully commence and/or complete clinical trials of its
      products on a timely basis or at all, obtain clinical data to support a
      pre-market approval application or timely file and receive FDA or other
      regulatory approvals of its products, or that such approvals will not be
      obtained in a timely manner or without the need for additional clinical
      trials; (iii) the Company's research and product development efforts and
      their relative success, including whether the Company has any meaningful
      sales of any new products resulting from such efforts; (iv) the cost
      effectiveness and efficiency of our manufacturing operations and
      production planning; (v) the strength of the economies in which the
      Company operates or will be operating, as well as the political
      stability of any of those geographic areas; (vi) future determinations
      by the Company to allocate resources to products and in directions not
      presently contemplated or (vii) the Company&#8217;s ability to launch MONOVISC
      in the U.S., if at all.</i> <i>Any delay in receiving any regulatory
      approvals may adversely affect the Company's competitive position.</i> <i>Even
      if regulatory approvals are obtained, there is a risk that meaningful
      sales of the products may not be achieved.</i> <i>There is also a risk
      that (i) the Company's existing distributors or customers will not
      continue to place orders at historical levels or that any of them will
      seek to modify or terminate existing arrangements, (ii) the Company's
      efforts to enter into long-term marketing and distribution arrangements,
      including with new international distributors for ORTHOVISC and
      MONOVISC, will not be successful, (iii) new distribution arrangements
      will not result in meaningful sales of the Company's products, (iv) the
      Company&#8217;s distributors will be unable to achieve performance and sales
      threshold milestones in its distribution agreements, (v) competitive
      products will adversely impact the Company's product sales, (vi) the
      estimated size(s) of the markets which the Company has targeted its
      products will fail to be achieved, (vii) lack of adequate coverage and
      reimbursement provided by governments and other third party payers for
      our products and services could have a material adverse effect on our
      results of operations, or (viii) increased sales of the Company's
      products, including HYVISC, ORTHOVISC , or its ophthalmic products, will
      not continue or sales will decrease or not reach historical sales
      levels, or even if such increases occur that such increases will improve
      gross margins, any of which may have a material adverse effect on the
      Company's business and operations.</i> <i>Certain other factors that
      might cause the Company's actual results to differ materially from those
      in the forward-looking statements include those set forth under the
      headings &quot;Business,&quot; &quot;Risk Factors&quot; and &quot;Management's Discussion and
      Analysis of Financial Condition and Results of Operations&quot; in the
      Company's Annual Report on Form 10-K for the year ended December 31,
      2009 and on Form 10-Q for the quarters ended March 31, 2010 and June 30,
      2010, as well as those described in the Company's other press releases
      and SEC filings.</i>
    </p>
    <div style="margin-bottom: 10pt; text-indent: 0pt; margin-left: 0pt; width: 100%; margin-right: 0pt">
      <div>
        <div style="text-align: left">

        </div>
      </div>
      <div style="page-break-after: always">
        <div style="text-align: center">

        </div>
        <div style="text-align: center">
          <hr style="height: 1.5pt; color: black">

        </div>
      </div>
      <div>
        <div style="text-align: right">

        </div>
      </div>
    </div>
    <div style="text-align:left">
    <table cellspacing="0" style="margin-bottom: 10.0px; font-size: 8pt; font-family: Times New Roman; width: 100%">
      <tr>
        <td colspan="16">
          &#160;
        </td>
      </tr>
      <tr>
        <td valign="top" colspan="16" style="padding-left: 0.0px; text-align: center">
          <b>Anika Therapeutics, Inc. and Subsidiaries</b>
        </td>
      </tr>
      <tr>
        <td valign="top" colspan="16" style="padding-left: 0.0px; text-align: center">
          <b>Consolidated Statements of Operations</b>
        </td>
      </tr>
      <tr>
        <td valign="top" colspan="16" style="padding-left: 0.0px; text-align: center">
          <b>(unaudited)</b>
        </td>
      </tr>
      <tr>
        <td>

        </td>
        <td>
          &#160;
        </td>
        <td>

        </td>
        <td colspan="6">

        </td>
        <td>
          &#160;
        </td>
        <td>

        </td>
        <td colspan="5">

        </td>
      </tr>
      <tr>
        <td>

        </td>
        <td>

        </td>
        <td valign="top" style="padding-left: 0.0px; text-align: center">
          <p style="margin-bottom: 0px; margin-top: 0px">
            &#160;
          </p>
        </td>
        <td valign="top" colspan="6" style="padding-left: 0.0px; text-align: center">
          <p style="margin-bottom: 0px; margin-top: 0px">
            <b>Three Months Ended June 30,</b>
          </p>
        </td>
        <td>

        </td>
        <td valign="top" style="padding-left: 0.0px; text-align: center">
          <p style="margin-bottom: 0px; margin-top: 0px">
            &#160;
          </p>
        </td>
        <td valign="top" colspan="5" style="padding-left: 0.0px; text-align: center">
          <p style="margin-bottom: 0px; margin-top: 0px">
            <b>Six Months Ended June 30,</b>
          </p>
        </td>
      </tr>
      <tr>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="border-bottom: solid black 1.0pt; padding-left: 0.0px; white-space: nowrap; text-align: center; padding-right: 0.0px">
          <b>2010</b>
        </td>
        <td style="border-bottom: solid black 1.0pt">
          &#160;
        </td>
        <td>
          &#160;
        </td>
        <td>

        </td>
        <td valign="bottom" style="border-bottom: solid black 1.0pt; padding-left: 0.0px; white-space: nowrap; text-align: center; padding-right: 0.0px">
          <b>2009</b>
        </td>
        <td style="border-bottom: solid black 1.0pt">
          &#160;
        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="border-bottom: solid black 1.0pt; padding-left: 0.0px; white-space: nowrap; text-align: center; padding-right: 0.0px">
          <b>2010</b>
        </td>
        <td style="border-bottom: solid black 1.0pt">
          &#160;
        </td>
        <td>
          &#160;
        </td>
        <td>

        </td>
        <td valign="bottom" style="border-bottom: solid black 1.0pt; padding-left: 0.0px; white-space: nowrap; text-align: center; padding-right: 0.0px">
          <b>2009</b>
        </td>
      </tr>
      <tr>
        <td valign="top" style="padding-left: 0.0px; text-align: left">
          Product revenue
        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; white-space: nowrap; text-align: right; padding-right: 0.0px">
          $
        </td>
        <td valign="bottom" style="padding-left: 0.0px; white-space: nowrap; text-align: right; padding-right: 0.0px">
          13,720,929
        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; white-space: nowrap; text-align: right; padding-right: 0.0px">
          $
        </td>
        <td valign="bottom" style="padding-left: 0.0px; white-space: nowrap; text-align: right; padding-right: 0.0px">
          8,770,763
        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; white-space: nowrap; text-align: right; padding-right: 0.0px">
          $
        </td>
        <td valign="bottom" style="padding-left: 0.0px; white-space: nowrap; text-align: right; padding-right: 0.0px">
          25,362,979
        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; white-space: nowrap; text-align: right; padding-right: 0.0px">
          17,289,836
        </td>
      </tr>
      <tr>
        <td valign="top" style="padding-left: 0.0px; padding-bottom: 2.0px; text-align: left">
          Licensing, milestone and contract revenue
        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="border-bottom: solid black 1.0pt; padding-left: 0.0px; white-space: nowrap; text-align: right; padding-right: 0.0px">
          778,871
        </td>
        <td style="border-bottom: solid black 1.0pt">
          &#160;
        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="border-bottom: solid black 1.0pt; padding-left: 0.0px; white-space: nowrap; text-align: right; padding-right: 0.0px">
          752,913
        </td>
        <td style="border-bottom: solid black 1.0pt">
          &#160;
        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="border-bottom: solid black 1.0pt; padding-left: 0.0px; white-space: nowrap; text-align: right; padding-right: 0.0px">
          1,602,908
        </td>
        <td style="border-bottom: solid black 1.0pt">
          &#160;
        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="border-bottom: solid black 1.0pt; padding-left: 0.0px; white-space: nowrap; text-align: right; padding-right: 0.0px">
          1,434,164
        </td>
      </tr>
      <tr>
        <td valign="top" style="padding-left: 20.0px; text-align: left">
          Total revenue
        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; white-space: nowrap; text-align: right; padding-right: 0.0px">
          14,499,800
        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; white-space: nowrap; text-align: right; padding-right: 0.0px">
          9,523,676
        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; white-space: nowrap; text-align: right; padding-right: 0.0px">
          26,965,887
        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; white-space: nowrap; text-align: right; padding-right: 0.0px">
          18,724,000
        </td>
      </tr>
      <tr>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td colspan="2">

        </td>
        <td>

        </td>
        <td colspan="3">

        </td>
        <td>

        </td>
        <td>

        </td>
        <td colspan="2">

        </td>
        <td>

        </td>
        <td colspan="2">
          &#160;
        </td>
      </tr>
      <tr>
        <td valign="top" style="padding-left: 0.0px; text-align: left">
          Operating expenses:
        </td>
        <td>

        </td>
        <td>

        </td>
        <td colspan="2">

        </td>
        <td>

        </td>
        <td colspan="3">

        </td>
        <td>

        </td>
        <td>

        </td>
        <td colspan="2">

        </td>
        <td>

        </td>
        <td colspan="2">

        </td>
      </tr>
      <tr>
        <td valign="top" style="padding-left: 20.0px; text-align: left">
          Cost of product revenue
        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; white-space: nowrap; text-align: right; padding-right: 0.0px">
          5,891,752
        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; white-space: nowrap; text-align: right; padding-right: 0.0px">
          3,294,160
        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; white-space: nowrap; text-align: right; padding-right: 0.0px">
          11,015,427
        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; white-space: nowrap; text-align: right; padding-right: 0.0px">
          6,505,826
        </td>
      </tr>
      <tr>
        <td valign="top" style="padding-left: 20.0px; text-align: left">
          Research &amp; development
        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; white-space: nowrap; text-align: right; padding-right: 0.0px">
          1,836,653
        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; white-space: nowrap; text-align: right; padding-right: 0.0px">
          2,286,229
        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; white-space: nowrap; text-align: right; padding-right: 0.0px">
          3,712,297
        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; white-space: nowrap; text-align: right; padding-right: 0.0px">
          4,480,537
        </td>
      </tr>
      <tr>
        <td valign="top" style="padding-left: 20.0px; padding-bottom: 2.0px; text-align: left">
          Selling, general &amp; administrative
        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="border-bottom: solid black 1.0pt; padding-left: 0.0px; white-space: nowrap; text-align: right; padding-right: 0.0px">
          4,967,346
        </td>
        <td style="border-bottom: solid black 1.0pt">
          &#160;
        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="border-bottom: solid black 1.0pt; padding-left: 0.0px; white-space: nowrap; text-align: right; padding-right: 0.0px">
          2,735,552
        </td>
        <td style="border-bottom: solid black 1.0pt">
          &#160;
        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="border-bottom: solid black 1.0pt; padding-left: 0.0px; white-space: nowrap; text-align: right; padding-right: 0.0px">
          9,256,324
        </td>
        <td style="border-bottom: solid black 1.0pt">
          &#160;
        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="border-bottom: solid black 1.0pt; padding-left: 0.0px; white-space: nowrap; text-align: right; padding-right: 0.0px">
          5,770,534
        </td>
      </tr>
      <tr>
        <td valign="top" style="padding-left: 0.0px; padding-bottom: 2.0px; text-align: left">
          Total operating expenses
        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="border-bottom: solid black 1.0pt; padding-left: 0.0px; white-space: nowrap; text-align: right; padding-right: 0.0px">
          12,695,751
        </td>
        <td style="border-bottom: solid black 1.0pt">
          &#160;
        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="border-bottom: solid black 1.0pt; padding-left: 0.0px; white-space: nowrap; text-align: right; padding-right: 0.0px">
          8,315,941
        </td>
        <td style="border-bottom: solid black 1.0pt">
          &#160;
        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="border-bottom: solid black 1.0pt; padding-left: 0.0px; white-space: nowrap; text-align: right; padding-right: 0.0px">
          23,984,048
        </td>
        <td style="border-bottom: solid black 1.0pt">
          &#160;
        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="border-bottom: solid black 1.0pt; padding-left: 0.0px; white-space: nowrap; text-align: right; padding-right: 0.0px">
          16,756,897
        </td>
      </tr>
      <tr>
        <td valign="top" style="padding-left: 0.0px; text-align: left">
          Income from operations
        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; white-space: nowrap; text-align: right; padding-right: 0.0px">
          1,804,049
        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; white-space: nowrap; text-align: right; padding-right: 0.0px">
          1,207,735
        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; white-space: nowrap; text-align: right; padding-right: 0.0px">
          2,981,839
        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; white-space: nowrap; text-align: right; padding-right: 0.0px">
          1,967,103
        </td>
      </tr>
      <tr>
        <td valign="top" style="padding-left: 20.0px; padding-bottom: 2.0px; text-align: left">
          Interest income (expense), net
        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="border-bottom: solid black 1.0pt; padding-left: 0.0px; white-space: nowrap; text-align: right; padding-right: 0.0px">
          (59,287
        </td>
        <td valign="bottom" style="border-bottom: solid black 1.0pt; padding-left: 0.0px; white-space: nowrap; text-align: left; padding-right: 0.0px">
          )
        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="border-bottom: solid black 1.0pt; padding-left: 0.0px; white-space: nowrap; text-align: right; padding-right: 0.0px">
          (1,382
        </td>
        <td valign="bottom" style="border-bottom: solid black 1.0pt; padding-left: 0.0px; white-space: nowrap; text-align: left; padding-right: 0.0px">
          )
        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="border-bottom: solid black 1.0pt; padding-left: 0.0px; white-space: nowrap; text-align: right; padding-right: 0.0px">
          (109,207
        </td>
        <td valign="bottom" style="border-bottom: solid black 1.0pt; padding-left: 0.0px; white-space: nowrap; text-align: left; padding-right: 0.0px">
          )
        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="border-bottom: solid black 1.0pt; padding-left: 0.0px; white-space: nowrap; text-align: right; padding-right: 0.0px">
          58
        </td>
      </tr>
      <tr>
        <td valign="top" style="padding-left: 0.0px; text-align: left">
          Income before income taxes
        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; white-space: nowrap; text-align: right; padding-right: 0.0px">
          1,744,762
        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; white-space: nowrap; text-align: right; padding-right: 0.0px">
          1,206,353
        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; white-space: nowrap; text-align: right; padding-right: 0.0px">
          2,872,632
        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; white-space: nowrap; text-align: right; padding-right: 0.0px">
          1,967,161
        </td>
      </tr>
      <tr>
        <td valign="top" style="padding-left: 20.0px; padding-bottom: 2.0px; text-align: left">
          Provision for income taxes
        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="border-bottom: solid black 1.0pt; padding-left: 0.0px; white-space: nowrap; text-align: right; padding-right: 0.0px">
          678,010
        </td>
        <td style="border-bottom: solid black 1.0pt">
          &#160;
        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="border-bottom: solid black 1.0pt; padding-left: 0.0px; white-space: nowrap; text-align: right; padding-right: 0.0px">
          250,579
        </td>
        <td style="border-bottom: solid black 1.0pt">
          &#160;
        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="border-bottom: solid black 1.0pt; padding-left: 0.0px; white-space: nowrap; text-align: right; padding-right: 0.0px">
          1,091,600
        </td>
        <td style="border-bottom: solid black 1.0pt">
          &#160;
        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="border-bottom: solid black 1.0pt; padding-left: 0.0px; white-space: nowrap; text-align: right; padding-right: 0.0px">
          488,667
        </td>
      </tr>
      <tr>
        <td valign="top" style="padding-left: 0.0px; padding-bottom: 4.0px; text-align: left">
          Net income
        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; white-space: nowrap; padding-bottom: 4.0px; text-align: right; padding-right: 0.0px">
          $
        </td>
        <td valign="bottom" style="border-bottom: double black 2.25pt; padding-left: 0.0px; white-space: nowrap; text-align: right; padding-right: 0.0px">
          1,066,752
        </td>
        <td style="border-bottom: double black 2.25pt">
          &#160;
        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; white-space: nowrap; padding-bottom: 4.0px; text-align: right; padding-right: 0.0px">
          $
        </td>
        <td valign="bottom" style="border-bottom: double black 2.25pt; padding-left: 0.0px; white-space: nowrap; text-align: right; padding-right: 0.0px">
          955,774
        </td>
        <td style="border-bottom: double black 2.25pt">
          &#160;
        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; white-space: nowrap; padding-bottom: 4.0px; text-align: right; padding-right: 0.0px">
          $
        </td>
        <td valign="bottom" style="border-bottom: double black 2.25pt; padding-left: 0.0px; white-space: nowrap; text-align: right; padding-right: 0.0px">
          1,781,032
        </td>
        <td style="border-bottom: double black 2.25pt">
          &#160;
        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; white-space: nowrap; padding-bottom: 4.0px; text-align: right; padding-right: 0.0px">
          $
        </td>
        <td valign="bottom" style="border-bottom: double black 2.25pt; padding-left: 0.0px; white-space: nowrap; text-align: right; padding-right: 0.0px">
          1,478,494
        </td>
      </tr>
      <tr>
        <td valign="top" style="padding-left: 0.0px; text-align: left">
          Basic net income per share:
        </td>
        <td>

        </td>
        <td>

        </td>
        <td colspan="2">

        </td>
        <td>

        </td>
        <td colspan="3">

        </td>
        <td>

        </td>
        <td>

        </td>
        <td colspan="2">

        </td>
        <td>

        </td>
        <td colspan="2">

        </td>
      </tr>
      <tr>
        <td valign="top" style="padding-left: 20.0px; text-align: left">
          Net income
        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; white-space: nowrap; text-align: right; padding-right: 0.0px">
          $
        </td>
        <td valign="bottom" style="padding-left: 0.0px; white-space: nowrap; text-align: right; padding-right: 0.0px">
          0.08
        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; white-space: nowrap; text-align: right; padding-right: 0.0px">
          $
        </td>
        <td valign="bottom" style="padding-left: 0.0px; white-space: nowrap; text-align: right; padding-right: 0.0px">
          0.08
        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; white-space: nowrap; text-align: right; padding-right: 0.0px">
          $
        </td>
        <td valign="bottom" style="padding-left: 0.0px; white-space: nowrap; text-align: right; padding-right: 0.0px">
          0.14
        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; white-space: nowrap; text-align: right; padding-right: 0.0px">
          $
        </td>
        <td valign="bottom" style="padding-left: 0.0px; white-space: nowrap; text-align: right; padding-right: 0.0px">
          0.13
        </td>
      </tr>
      <tr>
        <td valign="top" style="padding-left: 20.0px; text-align: left">
          Basic weighted average common shares outstanding
        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; white-space: nowrap; text-align: right; padding-right: 0.0px">
          12,645,889
        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; white-space: nowrap; text-align: right; padding-right: 0.0px">
          11,384,949
        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; white-space: nowrap; text-align: right; padding-right: 0.0px">
          12,630,398
        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; white-space: nowrap; text-align: right; padding-right: 0.0px">
          11,375,798
        </td>
      </tr>
      <tr>
        <td valign="top" style="padding-left: 0.0px; text-align: left">
          Diluted net income per share:
        </td>
        <td>

        </td>
        <td>

        </td>
        <td colspan="2">

        </td>
        <td>

        </td>
        <td colspan="3">

        </td>
        <td>

        </td>
        <td>

        </td>
        <td colspan="2">

        </td>
        <td>

        </td>
        <td colspan="2">

        </td>
      </tr>
      <tr>
        <td valign="top" style="padding-left: 20.0px; text-align: left">
          Net income
        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; white-space: nowrap; text-align: right; padding-right: 0.0px">
          $
        </td>
        <td valign="bottom" style="padding-left: 0.0px; white-space: nowrap; text-align: right; padding-right: 0.0px">
          0.08
        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; white-space: nowrap; text-align: right; padding-right: 0.0px">
          $
        </td>
        <td valign="bottom" style="padding-left: 0.0px; white-space: nowrap; text-align: right; padding-right: 0.0px">
          0.08
        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; white-space: nowrap; text-align: right; padding-right: 0.0px">
          $
        </td>
        <td valign="bottom" style="padding-left: 0.0px; white-space: nowrap; text-align: right; padding-right: 0.0px">
          0.13
        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; white-space: nowrap; text-align: right; padding-right: 0.0px">
          $
        </td>
        <td valign="bottom" style="padding-left: 0.0px; white-space: nowrap; text-align: right; padding-right: 0.0px">
          0.13
        </td>
      </tr>
      <tr>
        <td valign="top" style="padding-left: 20.0px; text-align: left">
          Diluted weighted average common shares outstanding
        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; white-space: nowrap; text-align: right; padding-right: 0.0px">
          13,642,323
        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; white-space: nowrap; text-align: right; padding-right: 0.0px">
          11,548,079
        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; white-space: nowrap; text-align: right; padding-right: 0.0px">
          13,637,309
        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; white-space: nowrap; text-align: right; padding-right: 0.0px">
          11,517,949
        </td>
      </tr>
    </table>
    </div>
    <div style="text-align:left">
    <table cellspacing="0" style="margin-bottom: 10.0px; font-size: 8pt; font-family: Times New Roman; width: 100%">
      <tr>
        <td colspan="9">
          &#160;
        </td>
      </tr>
      <tr>
        <td valign="top" colspan="9" style="padding-left: 0.0px; text-align: center">
          <p style="margin-bottom: 0px; margin-top: 0px">
            <b>Anika Therapeutics, Inc. and Subsidiaries</b>
          </p>
        </td>
      </tr>
      <tr>
        <td valign="top" colspan="9" style="padding-left: 0.0px; text-align: center">
          <b>Consolidated Balance Sheets</b>
        </td>
      </tr>
      <tr>
        <td valign="top" colspan="9" style="padding-left: 0.0px; text-align: center">
          <b>(unaudited)</b>
        </td>
      </tr>
      <tr>
        <td>

        </td>
        <td>
          &#160;
        </td>
        <td>

        </td>
        <td colspan="2">

        </td>
        <td>
          &#160;
        </td>
        <td>

        </td>
        <td colspan="2">

        </td>
      </tr>
      <tr>
        <td valign="top" style="padding-left: 0.0px; padding-bottom: 2.0px; text-align: center">
          <b>ASSETS</b>
        </td>
        <td>

        </td>
        <td valign="top" style="padding-left: 0.0px; padding-bottom: 2.0px; text-align: center">
          <p style="margin-bottom: 0px; margin-top: 0px">
            &#160;
          </p>
        </td>
        <td valign="top" colspan="2" style="border-bottom: solid black 1.0pt; padding-left: 0.0px; text-align: center">
          <p style="margin-bottom: 0px; margin-top: 0px">
            <b>June 30, 2010</b>
          </p>
        </td>
        <td>

        </td>
        <td valign="top" style="padding-left: 0.0px; padding-bottom: 2.0px; text-align: center">
          <p style="margin-bottom: 0px; margin-top: 0px">
            &#160;
          </p>
        </td>
        <td valign="top" colspan="2" style="border-bottom: solid black 1.0pt; padding-left: 0.0px; text-align: center">
          <p style="margin-bottom: 0px; margin-top: 0px">
            <b>December 31, 2009</b>
          </p>
        </td>
      </tr>
      <tr>
        <td valign="top" style="padding-left: 0.0px; text-align: left">
          Current assets:
        </td>
        <td>

        </td>
        <td>

        </td>
        <td colspan="2">

        </td>
        <td>

        </td>
        <td>

        </td>
        <td colspan="2">

        </td>
      </tr>
      <tr>
        <td valign="top" style="padding-left: 20.0px; text-align: left">
          Cash and cash equivalents
        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; white-space: nowrap; text-align: right; padding-right: 0.0px">
          $
        </td>
        <td valign="bottom" style="padding-left: 0.0px; white-space: nowrap; text-align: right; padding-right: 0.0px">
          23,648,822
        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; white-space: nowrap; text-align: right; padding-right: 0.0px">
          $
        </td>
        <td valign="bottom" style="padding-left: 0.0px; white-space: nowrap; text-align: right; padding-right: 0.0px">
          24,426,990
        </td>
        <td>

        </td>
      </tr>
      <tr>
        <td valign="top" style="padding-left: 20.0px; text-align: left">
          Short-term investments
        </td>
        <td>

        </td>
        <td>

        </td>
        <td colspan="2">

        </td>
        <td>

        </td>
        <td>

        </td>
        <td colspan="2">

        </td>
      </tr>
      <tr>
        <td valign="top" style="padding-left: 20.0px; text-align: left">
          Accounts receivable, net of reserves of $272,723 at June 30, 2010
          and $29,261 at December 31, 2009
        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; white-space: nowrap; text-align: right; padding-right: 0.0px">
          15,061,339
        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; white-space: nowrap; text-align: right; padding-right: 0.0px">
          11,778,743
        </td>
        <td>

        </td>
      </tr>
      <tr>
        <td valign="top" style="padding-left: 20.0px; text-align: left">
          Inventories
        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; white-space: nowrap; text-align: right; padding-right: 0.0px">
          8,369,659
        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; white-space: nowrap; text-align: right; padding-right: 0.0px">
          8,547,339
        </td>
        <td>

        </td>
      </tr>
      <tr>
        <td valign="top" style="padding-left: 20.0px; text-align: left">
          Current portion deferred income taxes
        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; white-space: nowrap; text-align: right; padding-right: 0.0px">
          2,215,936
        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; white-space: nowrap; text-align: right; padding-right: 0.0px">
          2,228,291
        </td>
        <td>

        </td>
      </tr>
      <tr>
        <td valign="top" style="padding-left: 20.0px; padding-bottom: 2.0px; text-align: left">
          Prepaid expenses and other
        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="border-bottom: solid black 1.0pt; padding-left: 0.0px; white-space: nowrap; text-align: right; padding-right: 0.0px">
          2,213,853
        </td>
        <td style="border-bottom: solid black 1.0pt">
          &#160;
        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="border-bottom: solid black 1.0pt; padding-left: 0.0px; white-space: nowrap; text-align: right; padding-right: 0.0px">
          2,892,858
        </td>
        <td style="border-bottom: solid black 1.0pt">
          &#160;
        </td>
      </tr>
      <tr>
        <td valign="top" style="padding-left: 40.0px; text-align: left">
          Total current assets
        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; white-space: nowrap; text-align: right; padding-right: 0.0px">
          51,509,609
        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; white-space: nowrap; text-align: right; padding-right: 0.0px">
          49,874,221
        </td>
        <td>

        </td>
      </tr>
      <tr>
        <td valign="top" style="padding-left: 0.0px; text-align: left">
          Property and equipment, at cost
        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; white-space: nowrap; text-align: right; padding-right: 0.0px">
          48,054,159
        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; white-space: nowrap; text-align: right; padding-right: 0.0px">
          47,172,403
        </td>
        <td>

        </td>
      </tr>
      <tr>
        <td valign="top" style="padding-left: 0.0px; padding-bottom: 2.0px; text-align: left">
          Less: accumulated depreciation
        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="border-bottom: solid black 1.0pt; padding-left: 0.0px; white-space: nowrap; text-align: right; padding-right: 0.0px">
          (12,060,186
        </td>
        <td valign="bottom" style="border-bottom: solid black 1.0pt; padding-left: 0.0px; white-space: nowrap; text-align: left; padding-right: 0.0px">
          )
        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="border-bottom: solid black 1.0pt; padding-left: 0.0px; white-space: nowrap; text-align: right; padding-right: 0.0px">
          (11,424,788
        </td>
        <td valign="bottom" style="border-bottom: solid black 1.0pt; padding-left: 0.0px; white-space: nowrap; text-align: left; padding-right: 0.0px">
          )
        </td>
      </tr>
      <tr>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; white-space: nowrap; text-align: right; padding-right: 0.0px">
          35,993,973
        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; white-space: nowrap; text-align: right; padding-right: 0.0px">
          35,747,615
        </td>
        <td>

        </td>
      </tr>
      <tr>
        <td valign="top" style="padding-left: 0.0px; text-align: left">
          Long-term deposits and other
        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; white-space: nowrap; text-align: right; padding-right: 0.0px">
          405,329
        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; white-space: nowrap; text-align: right; padding-right: 0.0px">
          413,228
        </td>
        <td>

        </td>
      </tr>
      <tr>
        <td valign="top" style="padding-left: 0.0px; text-align: left">
          Intangible assets, net
        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; white-space: nowrap; text-align: right; padding-right: 0.0px">
          27,789,999
        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; white-space: nowrap; text-align: right; padding-right: 0.0px">
          33,577,451
        </td>
        <td>

        </td>
      </tr>
      <tr>
        <td valign="top" style="padding-left: 0.0px; text-align: left">
          Deferred income taxes
        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; white-space: nowrap; text-align: right; padding-right: 0.0px">
          2,146,619
        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; white-space: nowrap; text-align: right; padding-right: 0.0px">
          3,506,362
        </td>
        <td>

        </td>
      </tr>
      <tr>
        <td valign="top" style="padding-left: 0.0px; padding-bottom: 2.0px; text-align: left">
          Goodwill
        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="border-bottom: solid black 1.0pt; padding-left: 0.0px; white-space: nowrap; text-align: right; padding-right: 0.0px">
          6,269,030
        </td>
        <td style="border-bottom: solid black 1.0pt">
          &#160;
        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="border-bottom: solid black 1.0pt; padding-left: 0.0px; white-space: nowrap; text-align: right; padding-right: 0.0px">
          7,488,036
        </td>
        <td style="border-bottom: solid black 1.0pt">
          &#160;
        </td>
      </tr>
      <tr>
        <td valign="top" style="padding-left: 0.0px; padding-bottom: 4.0px; text-align: left">
          Total Assets
        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; white-space: nowrap; padding-bottom: 4.0px; text-align: right; padding-right: 0.0px">
          $
        </td>
        <td valign="bottom" style="border-bottom: double black 2.25pt; padding-left: 0.0px; white-space: nowrap; text-align: right; padding-right: 0.0px">
          124,114,559
        </td>
        <td style="border-bottom: double black 2.25pt">
          &#160;
        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; white-space: nowrap; padding-bottom: 4.0px; text-align: right; padding-right: 0.0px">
          $
        </td>
        <td valign="bottom" style="border-bottom: double black 2.25pt; padding-left: 0.0px; white-space: nowrap; text-align: right; padding-right: 0.0px">
          130,606,913
        </td>
        <td style="border-bottom: double black 2.25pt">
          &#160;
        </td>
      </tr>
      <tr>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td colspan="2">

        </td>
        <td>

        </td>
        <td>

        </td>
        <td colspan="2">
          &#160;
        </td>
      </tr>
      <tr>
        <td valign="top" style="padding-left: 0.0px; text-align: center">
          <b>LIABILITIES AND STOCKHOLDERS&#8217; EQUITY</b>
        </td>
        <td>

        </td>
        <td>

        </td>
        <td colspan="2">

        </td>
        <td>

        </td>
        <td>

        </td>
        <td colspan="2">

        </td>
      </tr>
      <tr>
        <td valign="top" style="padding-left: 0.0px; text-align: left">
          Current liabilities:
        </td>
        <td>

        </td>
        <td>

        </td>
        <td colspan="2">

        </td>
        <td>

        </td>
        <td>

        </td>
        <td colspan="2">

        </td>
      </tr>
      <tr>
        <td valign="top" style="padding-left: 20.0px; text-align: left">
          Accounts payable
        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; white-space: nowrap; text-align: right; padding-right: 0.0px">
          $
        </td>
        <td valign="bottom" style="padding-left: 0.0px; white-space: nowrap; text-align: right; padding-right: 0.0px">
          7,413,932
        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; white-space: nowrap; text-align: right; padding-right: 0.0px">
          $
        </td>
        <td valign="bottom" style="padding-left: 0.0px; white-space: nowrap; text-align: right; padding-right: 0.0px">
          6,354,761
        </td>
        <td>

        </td>
      </tr>
      <tr>
        <td valign="top" style="padding-left: 20.0px; text-align: left">
          Accrued expenses
        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; white-space: nowrap; text-align: right; padding-right: 0.0px">
          4,784,900
        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; white-space: nowrap; text-align: right; padding-right: 0.0px">
          5,816,170
        </td>
        <td>

        </td>
      </tr>
      <tr>
        <td valign="top" style="padding-left: 20.0px; text-align: left">
          Deferred revenue
        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; white-space: nowrap; text-align: right; padding-right: 0.0px">
          2,700,000
        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; white-space: nowrap; text-align: right; padding-right: 0.0px">
          2,751,467
        </td>
        <td>

        </td>
      </tr>
      <tr>
        <td valign="top" style="padding-left: 20.0px; padding-bottom: 2.0px; text-align: left">
          Current portion of long-term debt
        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="border-bottom: solid black 1.0pt; padding-left: 0.0px; white-space: nowrap; text-align: right; padding-right: 0.0px">
          1,600,000
        </td>
        <td style="border-bottom: solid black 1.0pt">
          &#160;
        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="border-bottom: solid black 1.0pt; padding-left: 0.0px; white-space: nowrap; text-align: right; padding-right: 0.0px">
          1,600,000
        </td>
        <td style="border-bottom: solid black 1.0pt">
          &#160;
        </td>
      </tr>
      <tr>
        <td valign="top" style="padding-left: 40.0px; text-align: left">
          Total current liabilities
        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; white-space: nowrap; text-align: right; padding-right: 0.0px">
          16,498,832
        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; white-space: nowrap; text-align: right; padding-right: 0.0px">
          16,522,398
        </td>
        <td>

        </td>
      </tr>
      <tr>
        <td valign="top" style="padding-left: 0.0px; text-align: left">
          Other long-term liabilities
        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; white-space: nowrap; text-align: right; padding-right: 0.0px">
          1,618,862
        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; white-space: nowrap; text-align: right; padding-right: 0.0px">
          1,775,386
        </td>
        <td>

        </td>
      </tr>
      <tr>
        <td valign="top" style="padding-left: 0.0px; text-align: left">
          Long-term deferred revenue
        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; white-space: nowrap; text-align: right; padding-right: 0.0px">
          6,749,995
        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; white-space: nowrap; text-align: right; padding-right: 0.0px">
          8,099,996
        </td>
        <td>

        </td>
      </tr>
      <tr>
        <td valign="top" style="padding-left: 0.0px; text-align: left">
          Deferred tax liability
        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; white-space: nowrap; text-align: right; padding-right: 0.0px">
          7,425,009
        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; white-space: nowrap; text-align: right; padding-right: 0.0px">
          9,265,631
        </td>
        <td>

        </td>
      </tr>
      <tr>
        <td valign="top" style="padding-left: 0.0px; text-align: left">
          Long-term debt
        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; white-space: nowrap; text-align: right; padding-right: 0.0px">
          12,000,000
        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; white-space: nowrap; text-align: right; padding-right: 0.0px">
          12,800,000
        </td>
        <td>

        </td>
      </tr>
      <tr>
        <td valign="top" style="padding-left: 0.0px; text-align: left">
          Commitments and contingencies (Note 9)
        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; white-space: nowrap; text-align: right; padding-right: 0.0px">
          -
        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; white-space: nowrap; text-align: right; padding-right: 0.0px">
          -
        </td>
        <td>

        </td>
      </tr>
      <tr>
        <td valign="top" style="padding-left: 0.0px; text-align: left">
          Stockholders&#8217; equity:
        </td>
        <td>

        </td>
        <td>

        </td>
        <td colspan="2">

        </td>
        <td>

        </td>
        <td>

        </td>
        <td colspan="2">

        </td>
      </tr>
      <tr>
        <td valign="top" style="padding-left: 20.0px; text-align: left">
          Preferred stock, $.01 par value; 1,250,000 shares authorized, no
          shares issued and outstanding at June 30, 2010 and December 31, 2009
        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; white-space: nowrap; text-align: right; padding-right: 0.0px">
          -
        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; white-space: nowrap; text-align: right; padding-right: 0.0px">
          -
        </td>
        <td>

        </td>
      </tr>
      <tr>
        <td valign="top" style="padding-left: 20.0px; text-align: left">
          Common stock, $.01 par value; 30,000,000 shares authorized,
          13,477,647 shares issued and outstanding at June 30, 2010 and
          13,418,772 shares issued and outstanding at December 31, 2009
        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; white-space: nowrap; text-align: right; padding-right: 0.0px">
          134,776
        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; white-space: nowrap; text-align: right; padding-right: 0.0px">
          134,188
        </td>
        <td>

        </td>
      </tr>
      <tr>
        <td valign="top" style="padding-left: 20.0px; text-align: left">
          Additional paid-in-capital
        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; white-space: nowrap; text-align: right; padding-right: 0.0px">
          61,311,407
        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; white-space: nowrap; text-align: right; padding-right: 0.0px">
          60,539,768
        </td>
        <td>

        </td>
      </tr>
      <tr>
        <td valign="top" style="padding-left: 20.0px; text-align: left">
          Accumulated currency translation adjustment
        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; white-space: nowrap; text-align: right; padding-right: 0.0px">
          (4,874,900
        </td>
        <td valign="bottom" style="padding-left: 0.0px; white-space: nowrap; text-align: left; padding-right: 0.0px">
          )
        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; white-space: nowrap; text-align: right; padding-right: 0.0px">
          -
        </td>
        <td>

        </td>
      </tr>
      <tr>
        <td valign="top" style="padding-left: 20.0px; padding-bottom: 2.0px; text-align: left">
          Retained earnings
        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="border-bottom: solid black 1.0pt; padding-left: 0.0px; white-space: nowrap; text-align: right; padding-right: 0.0px">
          23,250,578
        </td>
        <td style="border-bottom: solid black 1.0pt">
          &#160;
        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="border-bottom: solid black 1.0pt; padding-left: 0.0px; white-space: nowrap; text-align: right; padding-right: 0.0px">
          21,469,546
        </td>
        <td style="border-bottom: solid black 1.0pt">
          &#160;
        </td>
      </tr>
      <tr>
        <td valign="top" style="padding-left: 40.0px; padding-bottom: 2.0px; text-align: left">
          Total stockholders&#8217; equity
        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="border-bottom: solid black 1.0pt; padding-left: 0.0px; white-space: nowrap; text-align: right; padding-right: 0.0px">
          79,821,861
        </td>
        <td style="border-bottom: solid black 1.0pt">
          &#160;
        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="border-bottom: solid black 1.0pt; padding-left: 0.0px; white-space: nowrap; text-align: right; padding-right: 0.0px">
          82,143,502
        </td>
        <td style="border-bottom: solid black 1.0pt">
          &#160;
        </td>
      </tr>
      <tr>
        <td valign="top" style="padding-left: 0.0px; padding-bottom: 4.0px; text-align: left">
          Total Liabilities and Stockholders&#8217; Equity
        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; white-space: nowrap; padding-bottom: 4.0px; text-align: right; padding-right: 0.0px">
          $
        </td>
        <td valign="bottom" style="border-bottom: double black 2.25pt; padding-left: 0.0px; white-space: nowrap; text-align: right; padding-right: 0.0px">
          124,114,559
        </td>
        <td style="border-bottom: double black 2.25pt">
          &#160;
        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; white-space: nowrap; padding-bottom: 4.0px; text-align: right; padding-right: 0.0px">
          $
        </td>
        <td valign="bottom" style="border-bottom: double black 2.25pt; padding-left: 0.0px; white-space: nowrap; text-align: right; padding-right: 0.0px">
          130,606,913
        </td>
        <td style="border-bottom: double black 2.25pt">
          &#160;
        </td>
      </tr>
    </table>
    </div>
    <div style="margin-bottom: 10pt; text-indent: 0pt; margin-left: 0pt; width: 100%; margin-right: 0pt">
      <div>
        <div style="text-align: left">

        </div>
      </div>
      <div style="page-break-after: always">
        <div style="text-align: center">

        </div>
        <div style="text-align: center">
          <hr style="height: 1.5pt; color: black">

        </div>
      </div>
      <div>
        <div style="text-align: right">

        </div>
      </div>
    </div>
    <div style="text-align:left">
    <table cellspacing="0" style="margin-bottom: 10.0px; font-size: 8pt; font-family: Times New Roman; width: 100%">
      <tr>
        <td colspan="22">
          &#160;
        </td>
      </tr>
      <tr>
        <td valign="top" colspan="22" style="padding-left: 0.0px; text-align: center">
          <p style="margin-bottom: 0px; margin-top: 0px">
            <b>Anika Therapeutics, Inc. and Subsidiaries</b>
          </p>
        </td>
      </tr>
      <tr>
        <td valign="top" colspan="22" style="padding-left: 0.0px; text-align: center">
          <p style="margin-bottom: 0px; margin-top: 0px">
            <b>Supplemental Financial Data</b>
          </p>
        </td>
      </tr>
      <tr>
        <td valign="top" colspan="22" style="padding-left: 0.0px; text-align: center">
          <p style="margin-bottom: 0px; margin-top: 0px">
            <b>Revenue by Product Line and Geographic Location</b>
          </p>
        </td>
      </tr>
      <tr>
        <td valign="top" colspan="22" style="padding-left: 0.0px; text-align: center">
          <b>(unaudited)</b>
        </td>
      </tr>
      <tr>
        <td>

        </td>
        <td>
          &#160;
        </td>
        <td colspan="2">

        </td>
        <td>
          &#160;
        </td>
        <td>

        </td>
        <td>
          &#160;
        </td>
        <td colspan="2">

        </td>
        <td>
          &#160;
        </td>
        <td>

        </td>
        <td>
          &#160;
        </td>
        <td>
          &#160;
        </td>
        <td colspan="2">

        </td>
        <td>
          &#160;
        </td>
        <td>

        </td>
        <td>
          &#160;
        </td>
        <td colspan="2">

        </td>
        <td>
          &#160;
        </td>
        <td>

        </td>
      </tr>
      <tr>
        <td>

        </td>
        <td>

        </td>
        <td colspan="2">

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td colspan="2">

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td colspan="2">

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td colspan="2">

        </td>
        <td>

        </td>
        <td>
          &#160;
        </td>
      </tr>
      <tr>
        <td>

        </td>
        <td>

        </td>
        <td valign="top" colspan="9" style="border-bottom: solid black 1.0pt; padding-left: 0.0px; text-align: center">
          <p style="margin-bottom: 0px; margin-top: 0px">
            <b>Quarter Ended June 30,</b>
          </p>
        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="top" colspan="9" style="border-bottom: solid black 1.0pt; padding-left: 0.0px; text-align: center">
          <b>Six Months Ended June 30,</b>
        </td>
      </tr>
      <tr>
        <td valign="top" style="padding-left: 0.0px; padding-bottom: 2.0px; text-align: left">
          <p style="margin-bottom: 0px; margin-top: 0px">
            <b>Product Line:</b>
          </p>
        </td>
        <td>

        </td>
        <td style="border-bottom: solid black 1.0pt">
          &#160;
        </td>
        <td valign="bottom" style="border-bottom: solid black 1.0pt; padding-left: 0.0px; white-space: nowrap; text-align: center; padding-right: 0.0px">
          <b>2010</b>
        </td>
        <td style="border-bottom: solid black 1.0pt">
          &#160;
        </td>
        <td valign="bottom" style="border-bottom: solid black 1.0pt; padding-left: 0.0px; white-space: nowrap; text-align: center; padding-right: 0.0px">
          <b>%</b>
        </td>
        <td style="border-bottom: solid black 1.0pt">
          &#160;
        </td>
        <td style="border-bottom: solid black 1.0pt">
          &#160;
        </td>
        <td valign="bottom" style="border-bottom: solid black 1.0pt; padding-left: 0.0px; white-space: nowrap; text-align: center; padding-right: 0.0px">
          <b>2009</b>
        </td>
        <td style="border-bottom: solid black 1.0pt">
          &#160;
        </td>
        <td valign="bottom" style="border-bottom: solid black 1.0pt; padding-left: 0.0px; white-space: nowrap; text-align: center; padding-right: 0.0px">
          <b>%</b>
        </td>
        <td>

        </td>
        <td>

        </td>
        <td style="border-bottom: solid black 1.0pt">
          &#160;
        </td>
        <td valign="bottom" style="border-bottom: solid black 1.0pt; padding-left: 0.0px; white-space: nowrap; text-align: center; padding-right: 0.0px">
          <b>2010</b>
        </td>
        <td style="border-bottom: solid black 1.0pt">
          &#160;
        </td>
        <td valign="bottom" style="border-bottom: solid black 1.0pt; padding-left: 0.0px; white-space: nowrap; text-align: center; padding-right: 0.0px">
          <b>%</b>
        </td>
        <td style="border-bottom: solid black 1.0pt">
          &#160;
        </td>
        <td style="border-bottom: solid black 1.0pt">
          &#160;
        </td>
        <td valign="bottom" style="border-bottom: solid black 1.0pt; padding-left: 0.0px; white-space: nowrap; text-align: center; padding-right: 0.0px">
          <b>2009</b>
        </td>
        <td style="border-bottom: solid black 1.0pt">
          &#160;
        </td>
        <td valign="bottom" style="border-bottom: solid black 1.0pt; padding-left: 0.0px; white-space: nowrap; text-align: center; padding-right: 0.0px">
          %
        </td>
      </tr>
      <tr>
        <td valign="top" style="padding-left: 15.0px; text-align: left">
          Orthobiologics
        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; white-space: nowrap; text-align: right; padding-right: 0.0px">
          $
        </td>
        <td valign="bottom" style="padding-left: 0.0px; white-space: nowrap; text-align: right; padding-right: 0.0px">
          7,702,028
        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; white-space: nowrap; text-align: right; padding-right: 0.0px">
          56%
        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; white-space: nowrap; text-align: right; padding-right: 0.0px">
          $
        </td>
        <td valign="bottom" style="padding-left: 0.0px; white-space: nowrap; text-align: right; padding-right: 0.0px">
          5,568,685
        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; white-space: nowrap; text-align: right; padding-right: 0.0px">
          63%
        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; white-space: nowrap; text-align: right; padding-right: 0.0px">
          $
        </td>
        <td valign="bottom" style="padding-left: 0.0px; white-space: nowrap; text-align: right; padding-right: 0.0px">
          14,623,443
        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; white-space: nowrap; text-align: right; padding-right: 0.0px">
          58%
        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; white-space: nowrap; text-align: right; padding-right: 0.0px">
          $
        </td>
        <td valign="bottom" style="padding-left: 0.0px; white-space: nowrap; text-align: right; padding-right: 0.0px">
          10,718,327
        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; white-space: nowrap; text-align: right; padding-right: 0.0px">
          62%
        </td>
      </tr>
      <tr>
        <td valign="top" style="padding-left: 15.0px; text-align: left">
          Dermal
        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; white-space: nowrap; text-align: right; padding-right: 0.0px">
          1,197,770
        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; white-space: nowrap; text-align: right; padding-right: 0.0px">
          9%
        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; white-space: nowrap; text-align: right; padding-right: 0.0px">
          88,080
        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; white-space: nowrap; text-align: right; padding-right: 0.0px">
          1%
        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; white-space: nowrap; text-align: right; padding-right: 0.0px">
          2,083,978
        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; white-space: nowrap; text-align: right; padding-right: 0.0px">
          8%
        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; white-space: nowrap; text-align: right; padding-right: 0.0px">
          138,174
        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; white-space: nowrap; text-align: right; padding-right: 0.0px">
          1%
        </td>
      </tr>
      <tr>
        <td valign="top" style="padding-left: 15.0px; text-align: left">
          Ophthalmic surgery
        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; white-space: nowrap; text-align: right; padding-right: 0.0px">
          2,851,512
        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; white-space: nowrap; text-align: right; padding-right: 0.0px">
          21%
        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; white-space: nowrap; text-align: right; padding-right: 0.0px">
          2,480,923
        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; white-space: nowrap; text-align: right; padding-right: 0.0px">
          28%
        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; white-space: nowrap; text-align: right; padding-right: 0.0px">
          5,435,970
        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; white-space: nowrap; text-align: right; padding-right: 0.0px">
          21%
        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; white-space: nowrap; text-align: right; padding-right: 0.0px">
          5,126,175
        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; white-space: nowrap; text-align: right; padding-right: 0.0px">
          30%
        </td>
      </tr>
      <tr>
        <td valign="top" style="padding-left: 15.0px; text-align: left">
          Surgical
        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; white-space: nowrap; text-align: right; padding-right: 0.0px">
          1,231,979
        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; white-space: nowrap; text-align: right; padding-right: 0.0px">
          9%
        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; white-space: nowrap; text-align: right; padding-right: 0.0px">
          21,475
        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; white-space: nowrap; text-align: right; padding-right: 0.0px">
          0%
        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; white-space: nowrap; text-align: right; padding-right: 0.0px">
          1,810,604
        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; white-space: nowrap; text-align: right; padding-right: 0.0px">
          7%
        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; white-space: nowrap; text-align: right; padding-right: 0.0px">
          58,225
        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; white-space: nowrap; text-align: right; padding-right: 0.0px">
          0%
        </td>
      </tr>
      <tr>
        <td valign="top" style="padding-left: 15.0px; padding-bottom: 2.0px; text-align: left">
          Veterinary
        </td>
        <td>

        </td>
        <td style="border-bottom: solid black 1.0pt">
          &#160;
        </td>
        <td valign="bottom" style="border-bottom: solid black 1.0pt; padding-left: 0.0px; white-space: nowrap; text-align: right; padding-right: 0.0px">
          737,640
        </td>
        <td style="border-bottom: solid black 1.0pt">
          &#160;
        </td>
        <td valign="bottom" style="border-bottom: solid black 1.0pt; padding-left: 0.0px; white-space: nowrap; text-align: right; padding-right: 0.0px">
          5%
        </td>
        <td style="border-bottom: solid black 1.0pt">
          &#160;
        </td>
        <td style="border-bottom: solid black 1.0pt">
          &#160;
        </td>
        <td valign="bottom" style="border-bottom: solid black 1.0pt; padding-left: 0.0px; white-space: nowrap; text-align: right; padding-right: 0.0px">
          611,600
        </td>
        <td style="border-bottom: solid black 1.0pt">
          &#160;
        </td>
        <td valign="bottom" style="border-bottom: solid black 1.0pt; padding-left: 0.0px; white-space: nowrap; text-align: right; padding-right: 0.0px">
          7%
        </td>
        <td>

        </td>
        <td>

        </td>
        <td style="border-bottom: solid black 1.0pt">
          &#160;
        </td>
        <td valign="bottom" style="border-bottom: solid black 1.0pt; padding-left: 0.0px; white-space: nowrap; text-align: right; padding-right: 0.0px">
          1,408,984
        </td>
        <td style="border-bottom: solid black 1.0pt">
          &#160;
        </td>
        <td valign="bottom" style="border-bottom: solid black 1.0pt; padding-left: 0.0px; white-space: nowrap; text-align: right; padding-right: 0.0px">
          6%
        </td>
        <td style="border-bottom: solid black 1.0pt">
          &#160;
        </td>
        <td style="border-bottom: solid black 1.0pt">
          &#160;
        </td>
        <td valign="bottom" style="border-bottom: solid black 1.0pt; padding-left: 0.0px; white-space: nowrap; text-align: right; padding-right: 0.0px">
          1,248,935
        </td>
        <td style="border-bottom: solid black 1.0pt">
          &#160;
        </td>
        <td valign="bottom" style="border-bottom: solid black 1.0pt; padding-left: 0.0px; white-space: nowrap; text-align: right; padding-right: 0.0px">
          7%
        </td>
      </tr>
      <tr>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="border-bottom: double black 2.25pt; padding-left: 0.0px; white-space: nowrap; text-align: right; padding-right: 0.0px">
          $
        </td>
        <td valign="bottom" style="border-bottom: double black 2.25pt; padding-left: 0.0px; white-space: nowrap; text-align: right; padding-right: 0.0px">
          13,720,929
        </td>
        <td style="border-bottom: double black 2.25pt">
          &#160;
        </td>
        <td valign="bottom" style="border-bottom: double black 2.25pt; padding-left: 0.0px; white-space: nowrap; text-align: right; padding-right: 0.0px">
          100%
        </td>
        <td style="border-bottom: double black 2.25pt">
          &#160;
        </td>
        <td valign="bottom" style="border-bottom: double black 2.25pt; padding-left: 0.0px; white-space: nowrap; text-align: right; padding-right: 0.0px">
          $
        </td>
        <td valign="bottom" style="border-bottom: double black 2.25pt; padding-left: 0.0px; white-space: nowrap; text-align: right; padding-right: 0.0px">
          8,770,763
        </td>
        <td style="border-bottom: double black 2.25pt">
          &#160;
        </td>
        <td valign="bottom" style="border-bottom: double black 2.25pt; padding-left: 0.0px; white-space: nowrap; text-align: right; padding-right: 0.0px">
          100%
        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="border-bottom: double black 2.25pt; padding-left: 0.0px; white-space: nowrap; text-align: right; padding-right: 0.0px">
          $
        </td>
        <td valign="bottom" style="border-bottom: double black 2.25pt; padding-left: 0.0px; white-space: nowrap; text-align: right; padding-right: 0.0px">
          25,362,979
        </td>
        <td style="border-bottom: double black 2.25pt">
          &#160;
        </td>
        <td valign="bottom" style="border-bottom: double black 2.25pt; padding-left: 0.0px; white-space: nowrap; text-align: right; padding-right: 0.0px">
          100%
        </td>
        <td style="border-bottom: double black 2.25pt">
          &#160;
        </td>
        <td valign="bottom" style="border-bottom: double black 2.25pt; padding-left: 0.0px; white-space: nowrap; text-align: right; padding-right: 0.0px">
          $
        </td>
        <td valign="bottom" style="border-bottom: double black 2.25pt; padding-left: 0.0px; white-space: nowrap; text-align: right; padding-right: 0.0px">
          17,289,836
        </td>
        <td style="border-bottom: double black 2.25pt">
          &#160;
        </td>
        <td valign="bottom" style="border-bottom: double black 2.25pt; padding-left: 0.0px; white-space: nowrap; text-align: right; padding-right: 0.0px">
          100%
        </td>
      </tr>
      <tr>
        <td>

        </td>
        <td>

        </td>
        <td colspan="2">

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td colspan="2">

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td colspan="2">

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td colspan="2">

        </td>
        <td>

        </td>
        <td>
          &#160;
        </td>
      </tr>
      <tr>
        <td>

        </td>
        <td>

        </td>
        <td colspan="2">

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td colspan="2">

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td colspan="2">

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td colspan="2">

        </td>
        <td>

        </td>
        <td>
          &#160;
        </td>
      </tr>
      <tr>
        <td valign="top" style="padding-left: 0.0px; text-align: left">
          Product gross profit
        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; white-space: nowrap; text-align: right; padding-right: 0.0px">
          $
        </td>
        <td valign="bottom" style="padding-left: 0.0px; white-space: nowrap; text-align: right; padding-right: 0.0px">
          7,829,177
        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; white-space: nowrap; text-align: right; padding-right: 0.0px">
          $
        </td>
        <td valign="bottom" style="padding-left: 0.0px; white-space: nowrap; text-align: right; padding-right: 0.0px">
          5,476,603
        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; white-space: nowrap; text-align: right; padding-right: 0.0px">
          $
        </td>
        <td valign="bottom" style="padding-left: 0.0px; white-space: nowrap; text-align: right; padding-right: 0.0px">
          14,347,552
        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; white-space: nowrap; text-align: right; padding-right: 0.0px">
          $
        </td>
        <td valign="bottom" style="padding-left: 0.0px; white-space: nowrap; text-align: right; padding-right: 0.0px">
          10,784,010
        </td>
        <td>

        </td>
        <td>

        </td>
      </tr>
      <tr>
        <td valign="top" style="padding-left: 0.0px; text-align: left">
          Product gross margin
        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; white-space: nowrap; text-align: right; padding-right: 0.0px">
          57%
        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; white-space: nowrap; text-align: right; padding-right: 0.0px">
          62%
        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; white-space: nowrap; text-align: right; padding-right: 0.0px">
          57%
        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; white-space: nowrap; text-align: right; padding-right: 0.0px">
          62%
        </td>
        <td>

        </td>
        <td>

        </td>
      </tr>
      <tr>
        <td>

        </td>
        <td>

        </td>
        <td colspan="2">

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td colspan="2">

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td colspan="2">

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td colspan="2">

        </td>
        <td>

        </td>
        <td>
          &#160;
        </td>
      </tr>
      <tr>
        <td>

        </td>
        <td>

        </td>
        <td colspan="2">

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td colspan="2">

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td colspan="2">

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td colspan="2">

        </td>
        <td>

        </td>
        <td>
          &#160;
        </td>
      </tr>
      <tr>
        <td>

        </td>
        <td>

        </td>
        <td valign="top" colspan="9" style="border-bottom: solid black 1.0pt; padding-left: 0.0px; text-align: center">
          <p style="margin-bottom: 0px; margin-top: 0px">
            <b>Quarter Ended June 30,</b>
          </p>
        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="top" colspan="9" style="border-bottom: solid black 1.0pt; padding-left: 0.0px; text-align: center">
          <b>Six Months Ended June 30,</b>
        </td>
      </tr>
      <tr>
        <td>

        </td>
        <td>

        </td>
        <td style="border-bottom: solid black 1.0pt">
          &#160;
        </td>
        <td valign="bottom" style="border-bottom: solid black 1.0pt; padding-left: 0.0px; white-space: nowrap; text-align: center; padding-right: 0.0px">
          <b>2010</b>
        </td>
        <td style="border-bottom: solid black 1.0pt">
          &#160;
        </td>
        <td valign="bottom" style="border-bottom: solid black 1.0pt; padding-left: 0.0px; white-space: nowrap; text-align: center; padding-right: 0.0px">
          <b>%</b>
        </td>
        <td style="border-bottom: solid black 1.0pt">
          &#160;
        </td>
        <td style="border-bottom: solid black 1.0pt">
          &#160;
        </td>
        <td valign="bottom" style="border-bottom: solid black 1.0pt; padding-left: 0.0px; white-space: nowrap; text-align: center; padding-right: 0.0px">
          <b>2009</b>
        </td>
        <td style="border-bottom: solid black 1.0pt">
          &#160;
        </td>
        <td valign="bottom" style="border-bottom: solid black 1.0pt; padding-left: 0.0px; white-space: nowrap; text-align: center; padding-right: 0.0px">
          <b>%</b>
        </td>
        <td>

        </td>
        <td>

        </td>
        <td style="border-bottom: solid black 1.0pt">
          &#160;
        </td>
        <td valign="bottom" style="border-bottom: solid black 1.0pt; padding-left: 0.0px; white-space: nowrap; text-align: center; padding-right: 0.0px">
          <b>2010</b>
        </td>
        <td style="border-bottom: solid black 1.0pt">
          &#160;
        </td>
        <td valign="bottom" style="border-bottom: solid black 1.0pt; padding-left: 0.0px; white-space: nowrap; text-align: center; padding-right: 0.0px">
          <b>%</b>
        </td>
        <td style="border-bottom: solid black 1.0pt">
          &#160;
        </td>
        <td style="border-bottom: solid black 1.0pt">
          &#160;
        </td>
        <td valign="bottom" style="border-bottom: solid black 1.0pt; padding-left: 0.0px; white-space: nowrap; text-align: center; padding-right: 0.0px">
          <b>2009</b>
        </td>
        <td style="border-bottom: solid black 1.0pt">
          &#160;
        </td>
        <td valign="bottom" style="border-bottom: solid black 1.0pt; padding-left: 0.0px; white-space: nowrap; text-align: center; padding-right: 0.0px">
          %
        </td>
      </tr>
      <tr>
        <td valign="top" style="padding-left: 0.0px; text-align: left">
          <p style="margin-bottom: 0px; margin-top: 0px">
            <b>Geographic Location:</b>
          </p>
        </td>
        <td>

        </td>
        <td colspan="2">

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td colspan="2">

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td colspan="2">

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td colspan="2">

        </td>
        <td>

        </td>
        <td>

        </td>
      </tr>
      <tr>
        <td valign="top" style="padding-left: 10.0px; text-align: left">
          United States
        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; white-space: nowrap; text-align: right; padding-right: 0.0px">
          $
        </td>
        <td valign="bottom" style="padding-left: 0.0px; white-space: nowrap; text-align: right; padding-right: 0.0px">
          <p style="margin-bottom: 0px; margin-top: 0px">
            8,859,769
          </p>
        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; white-space: nowrap; text-align: right; padding-right: 0.0px">
          65%
        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; white-space: nowrap; text-align: right; padding-right: 0.0px">
          $
        </td>
        <td valign="bottom" style="padding-left: 0.0px; white-space: nowrap; text-align: right; padding-right: 0.0px">
          6,461,662
        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; white-space: nowrap; text-align: right; padding-right: 0.0px">
          74%
        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; white-space: nowrap; text-align: right; padding-right: 0.0px">
          $
        </td>
        <td valign="bottom" style="padding-left: 0.0px; white-space: nowrap; text-align: right; padding-right: 0.0px">
          <p style="margin-bottom: 0px; margin-top: 0px">
            17,215,605
          </p>
        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; white-space: nowrap; text-align: right; padding-right: 0.0px">
          68%
        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; white-space: nowrap; text-align: right; padding-right: 0.0px">
          $
        </td>
        <td valign="bottom" style="padding-left: 0.0px; white-space: nowrap; text-align: right; padding-right: 0.0px">
          12,597,226
        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; white-space: nowrap; text-align: right; padding-right: 0.0px">
          73%
        </td>
      </tr>
      <tr>
        <td valign="top" style="padding-left: 10.0px; text-align: left">
          Europe
        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; white-space: nowrap; text-align: right; padding-right: 0.0px">
          <p style="margin-bottom: 0px; margin-top: 0px">
            3,638,865
          </p>
        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; white-space: nowrap; text-align: right; padding-right: 0.0px">
          26%
        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; white-space: nowrap; text-align: right; padding-right: 0.0px">
          <p style="margin-bottom: 0px; margin-top: 0px">
            1,322,041
          </p>
        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; white-space: nowrap; text-align: right; padding-right: 0.0px">
          15%
        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; white-space: nowrap; text-align: right; padding-right: 0.0px">
          <p style="margin-bottom: 0px; margin-top: 0px">
            6,185,547
          </p>
        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; white-space: nowrap; text-align: right; padding-right: 0.0px">
          24%
        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; white-space: nowrap; text-align: right; padding-right: 0.0px">
          2,805,409
        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; white-space: nowrap; text-align: right; padding-right: 0.0px">
          16%
        </td>
      </tr>
      <tr>
        <td valign="top" style="padding-left: 10.0px; padding-bottom: 2.0px; text-align: left">
          Other
        </td>
        <td>

        </td>
        <td style="border-bottom: solid black 1.0pt">
          &#160;
        </td>
        <td valign="bottom" style="border-bottom: solid black 1.0pt; padding-left: 0.0px; white-space: nowrap; text-align: right; padding-right: 0.0px">
          <p style="margin-bottom: 0px; margin-top: 0px">
            1,222,295
          </p>
        </td>
        <td style="border-bottom: solid black 1.0pt">
          &#160;
        </td>
        <td valign="bottom" style="border-bottom: solid black 1.0pt; padding-left: 0.0px; white-space: nowrap; text-align: right; padding-right: 0.0px">
          9%
        </td>
        <td>

        </td>
        <td style="border-bottom: solid black 1.0pt">
          &#160;
        </td>
        <td valign="bottom" style="border-bottom: solid black 1.0pt; padding-left: 0.0px; white-space: nowrap; text-align: right; padding-right: 0.0px">
          987,060
        </td>
        <td style="border-bottom: solid black 1.0pt">
          &#160;
        </td>
        <td valign="bottom" style="border-bottom: solid black 1.0pt; padding-left: 0.0px; white-space: nowrap; text-align: right; padding-right: 0.0px">
          11%
        </td>
        <td>

        </td>
        <td>

        </td>
        <td style="border-bottom: solid black 1.0pt">
          &#160;
        </td>
        <td valign="bottom" style="border-bottom: solid black 1.0pt; padding-left: 0.0px; white-space: nowrap; text-align: right; padding-right: 0.0px">
          <p style="margin-bottom: 0px; margin-top: 0px">
            1,961,827
          </p>
        </td>
        <td style="border-bottom: solid black 1.0pt">
          &#160;
        </td>
        <td valign="bottom" style="border-bottom: solid black 1.0pt; padding-left: 0.0px; white-space: nowrap; text-align: right; padding-right: 0.0px">
          8%
        </td>
        <td>

        </td>
        <td style="border-bottom: solid black 1.0pt">
          &#160;
        </td>
        <td valign="bottom" style="border-bottom: solid black 1.0pt; padding-left: 0.0px; white-space: nowrap; text-align: right; padding-right: 0.0px">
          1,887,201
        </td>
        <td style="border-bottom: solid black 1.0pt">
          &#160;
        </td>
        <td valign="bottom" style="border-bottom: solid black 1.0pt; padding-left: 0.0px; white-space: nowrap; text-align: right; padding-right: 0.0px">
          11%
        </td>
      </tr>
      <tr>
        <td valign="top" style="padding-left: 15.0px; padding-bottom: 4.0px; text-align: left">
          Total
        </td>
        <td>

        </td>
        <td valign="bottom" style="border-bottom: double black 2.25pt; padding-left: 0.0px; white-space: nowrap; text-align: right; padding-right: 0.0px">
          $
        </td>
        <td valign="bottom" style="border-bottom: double black 2.25pt; padding-left: 0.0px; white-space: nowrap; text-align: right; padding-right: 0.0px">
          <p style="margin-bottom: 0px; margin-top: 0px">
            13,720,929
          </p>
        </td>
        <td style="border-bottom: double black 2.25pt">
          &#160;
        </td>
        <td valign="bottom" style="border-bottom: double black 2.25pt; padding-left: 0.0px; white-space: nowrap; text-align: right; padding-right: 0.0px">
          100%
        </td>
        <td>

        </td>
        <td valign="bottom" style="border-bottom: double black 2.25pt; padding-left: 0.0px; white-space: nowrap; text-align: right; padding-right: 0.0px">
          $
        </td>
        <td valign="bottom" style="border-bottom: double black 2.25pt; padding-left: 0.0px; white-space: nowrap; text-align: right; padding-right: 0.0px">
          <p style="margin-bottom: 0px; margin-top: 0px">
            8,770,763
          </p>
        </td>
        <td style="border-bottom: double black 2.25pt">
          &#160;
        </td>
        <td valign="bottom" style="border-bottom: double black 2.25pt; padding-left: 0.0px; white-space: nowrap; text-align: right; padding-right: 0.0px">
          100%
        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="border-bottom: double black 2.25pt; padding-left: 0.0px; white-space: nowrap; text-align: right; padding-right: 0.0px">
          $
        </td>
        <td valign="bottom" style="border-bottom: double black 2.25pt; padding-left: 0.0px; white-space: nowrap; text-align: right; padding-right: 0.0px">
          <p style="margin-bottom: 0px; margin-top: 0px">
            25,362,979
          </p>
        </td>
        <td style="border-bottom: double black 2.25pt">
          &#160;
        </td>
        <td valign="bottom" style="border-bottom: double black 2.25pt; padding-left: 0.0px; white-space: nowrap; text-align: right; padding-right: 0.0px">
          100%
        </td>
        <td>

        </td>
        <td valign="bottom" style="border-bottom: double black 2.25pt; padding-left: 0.0px; white-space: nowrap; text-align: right; padding-right: 0.0px">
          $
        </td>
        <td valign="bottom" style="border-bottom: double black 2.25pt; padding-left: 0.0px; white-space: nowrap; text-align: right; padding-right: 0.0px">
          17,289,836
        </td>
        <td style="border-bottom: double black 2.25pt">
          &#160;
        </td>
        <td valign="bottom" style="border-bottom: double black 2.25pt; padding-left: 0.0px; white-space: nowrap; text-align: right; padding-right: 0.0px">
          100%
        </td>
      </tr>
    </table>
    </div>
    <p>

    </p>
    <p>
      CONTACT:<br>Anika Therapeutics, Inc.<br>Charles H. Sherwood, Ph.D., CEO,
      781-457-9000<br>or<br>Kevin W. Quinlan, CFO, 781-457-9000
    </p>
  </body>
</html>
</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
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