<SEC-DOCUMENT>0001157523-12-004178.txt : 20120802
<SEC-HEADER>0001157523-12-004178.hdr.sgml : 20120802
<ACCEPTANCE-DATETIME>20120802142706
ACCESSION NUMBER:		0001157523-12-004178
CONFORMED SUBMISSION TYPE:	8-K
PUBLIC DOCUMENT COUNT:		2
CONFORMED PERIOD OF REPORT:	20120802
ITEM INFORMATION:		Results of Operations and Financial Condition
ITEM INFORMATION:		Financial Statements and Exhibits
FILED AS OF DATE:		20120802
DATE AS OF CHANGE:		20120802

FILER:

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			ANIKA THERAPEUTICS INC
		CENTRAL INDEX KEY:			0000898437
		STANDARD INDUSTRIAL CLASSIFICATION:	SURGICAL & MEDICAL INSTRUMENTS & APPARATUS [3841]
		IRS NUMBER:				043145961
		STATE OF INCORPORATION:			MA
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		8-K
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	001-14027
		FILM NUMBER:		121002975

	BUSINESS ADDRESS:	
		STREET 1:		236 WEST CUMMINGS PARK
		CITY:			WOBURN
		STATE:			MA
		ZIP:			01801
		BUSINESS PHONE:		6179326616

	MAIL ADDRESS:	
		STREET 1:		236 WEST CUMMINGS PARK
		CITY:			WOBURN
		STATE:			MA
		ZIP:			01801

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	ANIKA RESEARCH INC
		DATE OF NAME CHANGE:	19930309
</SEC-HEADER>
<DOCUMENT>
<TYPE>8-K
<SEQUENCE>1
<FILENAME>a50363300.htm
<DESCRIPTION>ANIKA THERAPEUTICS, INC. 8K
<TEXT>
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      <font style="font-family: Times New Roman; font-size: 11pt">UNITED STATES</font><font style="font-family: Times New Roman; font-size: 11pt"><br style="font-family: Times New Roman; font-size: 11pt"></font><font style="font-family: Times New Roman; font-size: 11pt">SECURITIES
      AND EXCHANGE COMMISSION</font><br><font style="font-size: 11pt"><br style="font-size: 11pt"></font><font style="font-size: 11pt">Washington,
      D.C. 20549</font><font style="font-size: 11pt"><br style="font-size: 11pt"></font><font style="font-size: 11pt"><br style="font-size: 11pt"></font><font style="font-family: Times New Roman; font-size: 11pt">FORM
      8-K</font><font style="font-size: 11pt"><br style="font-size: 11pt"></font><font style="font-size: 11pt"><br style="font-size: 11pt"></font><font style="font-size: 11pt">CURRENT
      REPORT</font><font style="font-size: 11pt"><br style="font-size: 11pt"></font><font style="font-size: 11pt">PURSUANT
      TO SECTION 13 OR 15(d)</font><br><font style="font-size: 11pt">OF THE
      SECURITIES EXCHANGE ACT OF 1934</font><font style="font-size: 11pt"><br style="font-size: 11pt"></font><font style="font-size: 11pt"><br style="font-size: 11pt"></font><font style="font-family: Times New Roman; font-size: 11pt">Date
      of Report (Date of earliest event reported): August 2, 2012</font><font style="font-size: 11pt"><br style="font-size: 11pt"></font><font style="font-size: 11pt"><br style="font-size: 11pt"></font><font style="font-size: 11pt">Anika
      Therapeutics, Inc.</font><font style="font-size: 11pt"><br style="font-size: 11pt"></font><font style="font-size: 11pt">(</font><i><font style="font-size: 11pt">Exact
      name of registrant as specified in its charter</font></i><font style="font-size: 11pt">)</font>
    </p>
    <div style="text-align:center">
    <table cellspacing="0" style="font-family: Times New Roman; font-size: 10pt; width: 100%; margin-bottom: 10.0px; margin-left:auto;margin-right:auto">
      <tr>
        <td valign="bottom" style="padding-left: 0.0px; width: 33%; text-align: center">
          <p style="margin-top: 0px; margin-bottom: 0px">
            Massachusetts
          </p>
        </td>
        <td valign="bottom" style="padding-left: 0.0px; width: 34%; padding-right: 0.0px; white-space: nowrap; text-align: center">
          <p style="margin-top: 0px; margin-bottom: 0px">
            000-21326
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          <p style="margin-top: 0px; margin-bottom: 0px">
            04-314-5961
          </p>
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          <p style="margin-top: 0px; margin-bottom: 0px">
            <i>(State or other jurisdiction of</i><br><i>incorporation or
            organization)</i>
          </p>
        </td>
        <td valign="top" style="padding-left: 0.0px; width: 34%; text-align: center">
          <p style="margin-top: 0px; margin-bottom: 0px">
            <i>Commission file number</i>
          </p>
        </td>
        <td valign="top" style="padding-left: 0.0px; width: 33%; text-align: center">
          <p style="margin-top: 0px; margin-bottom: 0px">
            <i>(I.R.S. Employer<br>Identification No.)</i>
          </p>
        </td>
      </tr>
    </table>
    </div>
    <p>

    </p>
    <div style="text-align:center">
    <table cellspacing="0" style="font-family: Times New Roman; font-size: 10pt; width: 100%; margin-bottom: 10.0px; margin-left:auto;margin-right:auto">
      <tr>
        <td valign="top" style="padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: center">
          <p style="margin-top: 0px; margin-bottom: 0px">
            32 Wiggins Avenue, Bedford, MA 01730
          </p>
        </td>
      </tr>
      <tr>
        <td valign="top" style="padding-left: 0.0px; text-align: center">
          <p style="margin-top: 0px; margin-bottom: 0px">
            <i>(Address of principal executive offices) (Zip code)</i>
          </p>
        </td>
      </tr>
    </table>
    </div>
    <p style="white-space: nowrap; text-align: center">
      <br>
      <i><font style="font-family: Times New Roman; font-size: 10pt">Registrant&#8217;s
      telephone number, including area code:&#160;&#160;&#160;</font></i><font style="font-family: Times New Roman; font-size: 10pt">781-457-9000</font><br><br><br>
    </p>
    <p style="text-align: center">
      <i><font style="font-family: Times New Roman; font-size: 10pt">(Former
      name or former address, if changed since last report)</font></i><br>
    </p>
    <p>

    </p>
    <p>
      <font style="font-family: Times New Roman; font-size: 10pt">Check the
      appropriate box below if the Form 8-K filing is intended to
      simultaneously satisfy the filing obligations of the registrant under
      any of the following provisions:</font>
    </p>
    <p>
      <font style="font-family: Arial Unicode MS; font-size: 10pt">&#8414;</font>
      <font style="font-family: Times New Roman; font-size: 10pt">Written
      communications pursuant to Rule 425 under the Securities Act (17 CFR
      230.425)</font>
    </p>
    <p>
      <font style="font-family: Arial Unicode MS; font-size: 10pt">&#8414;</font>
      <font style="font-family: Times New Roman; font-size: 10pt">Soliciting
      material pursuant to Rule 14a-12 under the Exchange Act (17 CFR
      240.14a-12)</font>
    </p>
    <p>
      <font style="font-family: Arial Unicode MS; font-size: 10pt">&#8414;</font>
      <font style="font-family: Times New Roman; font-size: 10pt">Pre-commencement
      communications pursuant to Rule 14d-2(b) under the Exchange Act (17 CFR
      240.14d-2(b))</font>
    </p>
    <p>
      <font style="font-family: Arial Unicode MS; font-size: 10pt">&#8414;</font>
      <font style="font-family: Times New Roman; font-size: 10pt">Pre-commencement
      communications pursuant to Rule 13e-4(c) under the Exchange Act (17 CFR
      240.13e-4(c))</font>
    </p>
    <p>
      <br>

    </p>
    <div style="margin-right: 0pt; margin-bottom: 10pt; width: 100%; margin-left: 0pt; text-indent: 0pt">
      <div>
        <div style="text-align: left">

        </div>
      </div>
      <div style="page-break-after: always">
        <div style="text-align: center">

        </div>
        <div style="text-align: center">
          <hr style="height: 1.5pt; color: black">

        </div>
      </div>
      <div>
        <div style="text-align: right">

        </div>
      </div>
    </div>
    <p>

    </p>
    <p style="text-align: center">
      <b>Section 2--Financial Information</b>
    </p>
    <p>

    </p>
<div style="text-align:left">
    <table cellspacing="0" style="font-family: Times New Roman; font-size: 10pt; width: 100%; margin-bottom: 10.0px">
      <tr>
        <td valign="top" style="padding-left: 0.0px; width: 10%; text-align: left">
          Item 2.02.
        </td>
        <td valign="top" style="padding-left: 0.0px; width: 90%; text-align: left">
          Results of Operations and Financial Condition.
        </td>
      </tr>
    </table>
    </div>
    <p>

    </p>
    <p>
      The following information, including the exhibit attached hereto, is
      intended to be furnished and shall not be deemed &quot;filed&quot; for purposes of
      Section 18 of the Securities Exchange Act of 1934 (the &quot;Exchange Act&quot;)
      or otherwise subject to the liabilities of that section, nor shall it be
      deemed incorporated by reference in any filing under the Securities Act
      of 1933 or the Exchange Act, except as expressly set forth by specific
      reference in such filing.
    </p>
    <p>

    </p>
    <p>
      On August 1, 2012, Anika Therapeutics, Inc. issued a press release
      announcing its financial results for the second quarter ended June 30,
      2012.&#160;&#160;The full text of the press release is furnished as Exhibit 99.1
      hereto and is incorporated herein by reference.
    </p>
    <p>

    </p>
    <p style="text-align: center">
      <b>Section 9--Financial Statements and Exhibits</b>
    </p>
    <p>

    </p>
<div style="text-align:left">
    <table cellspacing="0" style="font-family: Times New Roman; font-size: 10pt; width: 100%; margin-bottom: 10.0px">
      <tr>
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          Item 9.01.
        </td>
        <td valign="top" style="padding-left: 0.0px; width: 90%; text-align: left">
          Financial Statements and Exhibits.
        </td>
      </tr>
    </table>
    </div>
    <p>

    </p>
    <p style="white-space: nowrap">
      (d)&#160;&#160;Exhibits.
    </p>
    <p>

    </p>
<div style="text-align:left">
    <table cellspacing="0" style="font-family: Times New Roman; font-size: 10pt; width: 100%; margin-bottom: 10.0px">
      <tr>
        <td valign="top" style="padding-left: 0.0px; width: 10%; padding-right: 0.0px; white-space: nowrap; text-align: left">
          99.1
        </td>
        <td valign="top" style="padding-left: 0.0px; width: 90%; text-align: left">
          Press Release of Anika Therapeutics, Inc. dated August 1, 2012.
        </td>
      </tr>
    </table>
    </div>
    <p>

    </p>
    <p>

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          <hr style="height: 1.5pt; color: black">

        </div>
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        <div style="text-align: right">

        </div>
      </div>
    </div>
    <p>

    </p>
    <p style="text-align: center">
      <font style="font-family: Times New Roman; font-size: 10pt">SIGNATURE</font><br>
    </p>
    <p>
      Pursuant to the requirements of the Securities Exchange Act of 1934, the
      registrant has duly caused this report to be signed on its behalf by the
      undersigned hereunto duly authorized.
    </p>
    <p>

    </p>
    <div style="text-align:center">
    <table cellspacing="0" style="font-family: Times New Roman; font-size: 10pt; width: 100%; margin-bottom: 10.0px; margin-left:auto;margin-right:auto">
      <tr>
        <td style="width: 30%">

        </td>
        <td valign="top" style="padding-left: 0.0px; width: 30%; text-align: left">
          &#160;
        </td>
        <td colspan="3" valign="top" style="padding-left: 0.0px; text-align: left">
          <p style="margin-top: 0px; margin-bottom: 0px">
            Anika Therapeutics, Inc.
          </p>
        </td>
      </tr>
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        <td style="width: 30%">

        </td>
        <td style="width: 30%">

        </td>
        <td colspan="3" valign="top" style="padding-left: 0.0px; text-align: left">
          <p style="margin-top: 0px; margin-bottom: 0px">
            &#160;
          </p>
        </td>
      </tr>
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        <td valign="top" style="padding-bottom: 2.0px; padding-left: 0.0px; width: 30%; text-align: left">
          <p style="margin-top: 0px; margin-bottom: 0px">
            Dated: August 2, 2012
          </p>
        </td>
        <td style="width: 30%">

        </td>
        <td valign="top" style="padding-bottom: 2.0px; padding-left: 0.0px; width: 3%; text-align: left">
          By:
        </td>
        <td valign="top" style="border-bottom: solid black 1.0pt; padding-left: 0.0px; width: 2%; text-align: left">
          &#160;
        </td>
        <td valign="top" style="border-bottom: solid black 1.0pt; padding-left: 0.0px; width: 35%; text-align: left">
          <p style="margin-top: 0px; margin-bottom: 0px">
            /s/ Kevin W. Quinlan
          </p>
        </td>
      </tr>
      <tr>
        <td style="width: 30%">

        </td>
        <td style="width: 30%">

        </td>
        <td valign="top" style="padding-left: 0.0px; width: 3%; text-align: left">
          <p style="margin-top: 0px; margin-bottom: 0px">
            &#160;
          </p>
        </td>
        <td valign="top" style="padding-left: 0.0px; width: 2%; text-align: left">
          &#160;
        </td>
        <td valign="top" style="padding-left: 0.0px; width: 35%; text-align: left">
          <p style="margin-top: 0px; margin-bottom: 0px">
            Kevin W. Quinlan
          </p>
        </td>
      </tr>
      <tr>
        <td style="width: 30%">

        </td>
        <td style="width: 30%">

        </td>
        <td valign="top" style="padding-left: 0.0px; width: 3%; text-align: left">
          <p style="margin-top: 0px; margin-bottom: 0px">
            &#160;
          </p>
        </td>
        <td style="width: 2%">

        </td>
        <td valign="top" style="padding-left: 0.0px; width: 35%; text-align: left">
          <p style="margin-top: 0px; margin-bottom: 0px">
            Chief Financial Officer
          </p>
        </td>
      </tr>
    </table>
    </div>
    <p>

    </p>
    <div style="margin-right: 0pt; margin-bottom: 10pt; width: 100%; margin-left: 0pt; text-indent: 0pt">
      <div>
        <div style="text-align: left">

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      </div>
      <div style="page-break-after: always">
        <div style="text-align: center">

        </div>
        <div style="text-align: center">
          <hr style="height: 1.5pt; color: black">

        </div>
      </div>
      <div>
        <div style="text-align: right">

        </div>
      </div>
    </div>
    <p>

    </p>
    <p style="text-align: center">
      Exhibit Index<br><br>
    </p>
<div style="text-align:left">
    <table cellspacing="0" style="font-family: Times New Roman; font-size: 10pt; width: 100%; margin-bottom: 10.0px">
      <tr>
        <td valign="top" style="padding-left: 0.0px; width: 12%; padding-right: 0.0px; white-space: nowrap; text-align: left">
          99.1
        </td>
        <td valign="top" style="padding-left: 0.0px; width: 88%; text-align: left">
          <p style="margin-top: 0px; margin-bottom: 0px">
            Press Release of Anika Therapeutics, Inc. dated August 1, 2012.
          </p>
        </td>
      </tr>
    </table>
    </div>
    <p>

    </p>
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<DOCUMENT>
<TYPE>EX-99.1
<SEQUENCE>2
<FILENAME>a50363300ex99-1.htm
<DESCRIPTION>EXHIBIT 99.1
<TEXT>
<html>
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    <title></title>
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    <p style="text-align: right">
      <b>Exhibit 99.1</b>
    </p>
    <p style="text-align: center">
      <font style="font-family: Times New Roman; font-size: 12pt"><b>Anika
      Therapeutics Reports Record Second Quarter Revenue and Earnings</b></font>
    </p>
    <p style="text-align: center">

    </p>
    <p style="text-align: center">
      <i><font style="font-family: Times New Roman; font-size: 12pt"><b>Total
      Revenue Grows 22%; Earnings Increase 53% to $0.26 per Share</b></font></i>
    </p>
    <p>
      BEDFORD, Mass.--(BUSINESS WIRE)--August 1, 2012--Anika Therapeutics,
      Inc. (Nasdaq: ANIK), a leader in products for tissue protection,
      healing, and repair, based on hyaluronic acid (&#8220;HA&#8221;) technology, today
      reported financial results for the quarter ended June 30, 2012.
    </p>
    <p>
      <b>Revenue</b>
    </p>
    <p>
      For the second quarter of 2012, Anika&#8217;s total revenue increased 22% to
      $19.6 million, from $16.1 million in the second quarter last year. This
      growth was primarily driven by higher shipments of Anika&#8217;s ophthalmic
      products, as well as strong domestic and international sales of the
      company&#8217;s flagship product, Orthovisc<sup>&#174;</sup>.
    </p>
    <p>
      For the six-month period ended June 30, 2012, total revenue increased
      22% to $34.0 million, from $27.9 million in the same period last year.
    </p>
    <p>
      <b>Product Gross Margin</b>
    </p>
    <p>
      Driven by higher production volume, product gross margin for the second
      quarter of 2012 increased to 57.2%, from 56.8% in the second quarter
      last year.
    </p>
    <p>
      For the six-month period ended June 30, 2012, product gross margin
      increased to 55.4%, from 53.7% in the first six months of 2011.
    </p>
    <p>
      <b>Operating and Net Income</b>
    </p>
    <p>
      Operating income for the second quarter of 2012 increased to $6.1
      million, from $3.7 million in the same period in 2011. Net income rose
      to $3.7 million, or $0.26 per diluted share, from $2.3 million, or $0.17
      per diluted share, in the second quarter a year earlier. The company&#8217;s
      improved profitability was primarily driven by a combination of revenue
      growth, higher gross margin, and lower operating expenses. The company&#8217;s
      effective tax rate for the second quarter of 2012 was 38.6%, compared
      with 37.2% for the second quarter of 2011.
    </p>
    <p>
      For the six-month period ended June 30, 2012, net income rose to $5.6
      million, or $0.39 per diluted share, from $2.6 million, or $0.19 per
      diluted share, in the first six months of 2011.
    </p>
    <p>
      <b>Operating Expenses</b>
    </p>
    <p>
      Research and development expenses for the second quarter of 2012
      decreased to $1.3 million, from $1.6 million in the second quarter last
      year. Anika continues to expect R&amp;D expense to increase modestly in the
      second half of 2012 on a year-over-year basis due to the anticipated
      initiation of preclinical and clinical studies.
    </p>
    <div style="margin-right: 0pt; width: 100%; margin-bottom: 10pt; margin-left: 0pt; text-indent: 0pt">
      <div>
        <div style="text-align: left">

        </div>
      </div>
      <div style="page-break-after: always">
        <div style="text-align: center">

        </div>
        <div style="text-align: center">
          <hr style="height: 1.5pt; color: black">

        </div>
      </div>
      <div>
        <div style="text-align: right">

        </div>
      </div>
    </div>
    <p>
      Selling, general and administrative expenses in the second quarter of
      2012 decreased to $4.1 million, from $4.2 million in the second quarter
      of 2011. The decrease was primarily due to placing in service the
      remainder of the company&#8217;s Bedford manufacturing facility. Prior to the
      first quarter of 2012, the previously unoccupied space was expensed to
      SG&amp;A.
    </p>
    <p>
      <b>Cash and Cash Equivalents</b>
    </p>
    <p>
      Anika&#8217;s cash and cash equivalents at June 30, 2012 were $37.9 million,
      compared with $34.0 million at March 31, 2012. The increase was
      primarily the result of higher profitability and collections on accounts
      receivable.
    </p>
    <p>
      <b>Management Commentary</b>
    </p>
    <p>
      &#8220;Anika concluded the first half of 2012 with all-time record quarterly
      revenue and record second-quarter earnings, while making solid progress
      toward key strategic goals,&#8221; said Charles H. Sherwood, Ph.D., president
      and chief executive officer. &#8220;Total revenue was up 22% from the second
      quarter last year, driven primarily by strong sales of our flagship
      product, Orthovisc<sup>&#174;</sup>, both domestically and
      internationally and increased shipments in our Ophthalmic franchise.
      This growth was somewhat offset by year-over-year declines in sales of
      Monovisc<sup>&#174;</sup> internationally, as well as slower sales of
      our products by Anika S.r.l.&#8221;
    </p>
    <p>
      &#8220;We made solid operational progress in the second quarter,&#8221; said
      Sherwood. &#8220;We closed Anika&#8217;s facility in Woburn, Mass. and consolidated
      all of our manufacturing at our new facility in Bedford, Mass., by the
      end of the quarter as planned. We had a positive meeting with the FDA
      regarding our PMA application for Monovisc, and moved closer to starting
      patient enrollment in clinical trials for two key pipeline products.&#8221;
    </p>
    <p>
      &#8220;Anika is starting the second half of 2012 with strong forward
      momentum,&#8221; Sherwood said. &#8220;Completing the manufacturing consolidation in
      Bedford allows us to strengthen our focus on our product pipeline and
      distribution network to drive top-line growth.&#8221;
    </p>
    <p>
      <b>Conference Call Information</b>
    </p>
    <p>
      Anika will hold a conference call to discuss its financial results,
      business highlights and outlook tomorrow, Thursday, August 2, 2012 at
      9:00 a.m. ET. In addition, the company will answer questions concerning
      business and financial developments and trends, and other business and
      financial matters affecting the company, some of the responses to which
      may contain information that has not been previously disclosed.
    </p>
    <p>
      To listen to the conference call, dial 866-783-2144 (international
      callers dial 857-350-1603) and use the passcode 77982694. Please call
      approximately 10 minutes before the starting time and reference Anika
      Therapeutics. In addition, the conference call will be available through
      a live audio webcast in the &#8220;Investor Relations&#8221; section of the Anika
      Therapeutics website, <u>www.anikatherapeutics.com</u>. An accompanying
      slide presentation also can be accessed via the Anika Therapeutics
      website. The conference call will be archived and accessible on the same
      website shortly after the conclusion of the call.
    </p>
    <div style="margin-right: 0pt; margin-bottom: 10pt; width: 100%; margin-left: 0pt; text-indent: 0pt">
      <div>
        <div style="text-align: left">

        </div>
      </div>
      <div style="page-break-after: always">
        <div style="text-align: center">

        </div>
        <div style="text-align: center">
          <hr style="height: 1.5pt; color: black">

        </div>
      </div>
      <div>
        <div style="text-align: right">

        </div>
      </div>
    </div>
    <p>
      <b>About Anika Therapeutics, Inc.</b>
    </p>
    <p>
      Headquartered in Bedford, Mass., Anika Therapeutics, Inc.<u><b> </b></u>develops,
      manufactures and commercializes therapeutic products for tissue
      protection, healing, and repair. These products are based on hyaluronic
      acid (HA), a naturally occurring, biocompatible polymer found throughout
      the body. Anika&#8217;s products range from orthopedic/joint health solutions
      led by Orthovisc, a treatment for osteoarthritis of the knee, to
      surgical aids in the ophthalmic and anti-adhesion fields. The company
      also offers<u><b> </b></u>aesthetic dermal fillers for the correction of
      facial wrinkles. Anika&#8217;s Italian subsidiary, Anika S.r.l., provides
      complementary HA products in orthopedic/joint health and anti-adhesion,
      as well as therapeutics in new areas such as advanced wound treatment
      and ear, nose and throat care. Anika S.r.l.&#8217;s regenerative tissue
      technology advances Anika&#8217;s vision to offer therapeutic products that go
      beyond pain relief to protect and restore damaged tissue.
    </p>
    <p>
      <i>The statements made in this press release which are not statements of
      historical fact are forward-looking statements within the meaning of
      Section 27A of the Securities Act of 1933, as amended, and Section 21E
      of the Securities Exchange Act of 1934, as amended.</i> <i>These
      statements include, but are not limited to, those relating to: (i) FDA
      review of our PMA application for Monovisc, and (ii) expectations
      regarding research and development spending in future quarters. These
      statements are based upon the current beliefs and expectations of the
      company's management and are subject to significant risks, uncertainties
      and other factors.</i> <i>The company's actual results could differ
      materially from any anticipated future results, performance or
      achievements described in the forward-looking statements as a result of
      a number of factors including (i) the company's ability to successfully
      commence and/or complete clinical trials of its products on a timely
      basis or at all, obtain clinical data to support a pre-market approval
      application or timely file and receive FDA or other regulatory approvals
      or clearances of its products and Bedford facility, or that such
      approvals will not be obtained in a timely manner or without the need
      for additional clinical trials, other testing or regulatory submissions,
      as applicable; (ii) the company's research and product development
      efforts and their relative success, including whether the company has
      any meaningful sales of any new products resulting from such efforts;
      (iii) the cost effectiveness and efficiency of our clinical studies,
      manufacturing operations and production planning; (iv) the strength of
      the economies in which the company operates or will be operating, as
      well as the political stability of any of those geographic areas; (v)
      future determinations by the company to allocate resources to products
      and in directions not presently contemplated, (vi) the company&#8217;s ability
      to launch Monovisc in the U.S., if at all; (vii) the company&#8217;s ability
      to successfully resolve its appeal hearing regarding the FDA&#8217;s
      non-approvable letter for Monovisc, and the timing and results of such
      review; (viii) the company&#8217;s ability to provide an adequate and timely
      supply of its ophthalmic, Orthovisc and other products to its customers,
      (ix) our ability to successfully manage and turnaround Anika S.r.l.&#8217;s
      business, and (x) the company&#8217;s ability to achieve its stated growth
      targets.</i> <i>Certain other factors that might cause the company's
      actual results to differ materially from those in the forward-looking
      statements include those set forth under the headings &quot;Business,&quot; &quot;Risk
      Factors&quot; and &quot;Management's Discussion and Analysis of Financial
      Condition and Results of Operations&quot; in the company's Annual Report on
      Form 10-K for the year ended December 31, 2011, as well as those
      described in the company's other press releases and SEC filings.</i>
    </p>
    <div style="margin-right: 0pt; margin-bottom: 10pt; width: 100%; margin-left: 0pt; text-indent: 0pt">
      <div>
        <div style="text-align: left">

        </div>
      </div>
      <div style="page-break-after: always">
        <div style="text-align: center">

        </div>
        <div style="text-align: center">
          <hr style="height: 1.5pt; color: black">

        </div>
      </div>
      <div>
        <div style="text-align: right">

        </div>
      </div>
    </div>
<div style="text-align:left">
    <table cellspacing="0" style="font-family: Times New Roman; font-size: 8pt; margin-bottom: 10.0px; width: 100%">
      <tr>
        <td colspan="17">
          &#160;
        </td>
      </tr>
      <tr>
        <td colspan="17" valign="top" style="padding-left: 0.0px; text-align: center">
          <b>Anika Therapeutics, Inc. and Subsidiaries</b>
        </td>
      </tr>
      <tr>
        <td colspan="17" valign="top" style="padding-left: 0.0px; text-align: center">
          Condensed Consolidated Statements of Operations
        </td>
      </tr>
      <tr>
        <td colspan="17" valign="top" style="padding-left: 0.0px; text-align: center">
          (unaudited)
        </td>
      </tr>
      <tr>
        <td>

        </td>
        <td>
          &#160;
        </td>
        <td colspan="7">

        </td>
        <td>
          &#160;
        </td>
        <td colspan="7">

        </td>
      </tr>
      <tr>
        <td>

        </td>
        <td>

        </td>
        <td colspan="7" valign="top" style="padding-left: 0.0px; text-align: center">
          <b>Three Months Ended June 30,</b>
        </td>
        <td>

        </td>
        <td colspan="7" valign="top" style="padding-left: 0.0px; text-align: center">
          <b>Six Months Ended June 30,</b>
        </td>
      </tr>
      <tr>
        <td>

        </td>
        <td>

        </td>
        <td colspan="3" valign="bottom" style="border-bottom: solid black 1.0pt; padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: center">
          <b>2012</b>
        </td>
        <td>
          &#160;
        </td>
        <td style="border-bottom: solid black 1.0pt">
          &#160;
        </td>
        <td colspan="2" valign="bottom" style="border-bottom: solid black 1.0pt; padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: center">
          <b>2011</b>
        </td>
        <td>

        </td>
        <td colspan="3" valign="bottom" style="border-bottom: solid black 1.0pt; padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: center">
          <b>2012</b>
        </td>
        <td>
          &#160;
        </td>
        <td colspan="3" valign="bottom" style="border-bottom: solid black 1.0pt; padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: center">
          <b>2011</b>
        </td>
      </tr>
      <tr>
        <td valign="top" style="padding-left: 0.0px; text-align: left">
          Product revenue
        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: right">
          $
        </td>
        <td valign="bottom" style="padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: right">
          18,882,277
        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: right">
          $
        </td>
        <td valign="bottom" style="padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: right">
          15,414,681
        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: right">
          $
        </td>
        <td valign="bottom" style="padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: right">
          32,495,605
        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: right">
          $
        </td>
        <td valign="bottom" style="padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: right">
          26,474,840
        </td>
        <td>

        </td>
      </tr>
      <tr>
        <td valign="top" style="padding-bottom: 2.0px; padding-left: 0.0px; text-align: left">
          Licensing, milestone and contract revenue
        </td>
        <td>

        </td>
        <td style="border-bottom: solid black 1.0pt">
          &#160;
        </td>
        <td valign="bottom" style="border-bottom: solid black 1.0pt; padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: right">
          742,492
        </td>
        <td style="border-bottom: solid black 1.0pt">
          &#160;
        </td>
        <td>

        </td>
        <td style="border-bottom: solid black 1.0pt">
          &#160;
        </td>
        <td valign="bottom" style="border-bottom: solid black 1.0pt; padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: right">
          726,171
        </td>
        <td style="border-bottom: solid black 1.0pt">
          &#160;
        </td>
        <td>

        </td>
        <td style="border-bottom: solid black 1.0pt">
          &#160;
        </td>
        <td valign="bottom" style="border-bottom: solid black 1.0pt; padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: right">
          1,489,824
        </td>
        <td style="border-bottom: solid black 1.0pt">
          &#160;
        </td>
        <td>

        </td>
        <td style="border-bottom: solid black 1.0pt">
          &#160;
        </td>
        <td valign="bottom" style="border-bottom: solid black 1.0pt; padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: right">
          1,403,691
        </td>
        <td style="border-bottom: solid black 1.0pt">
          &#160;
        </td>
      </tr>
      <tr>
        <td valign="top" style="padding-left: 20.0px; text-align: left">
          Total revenue
        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: right">
          19,624,769
        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: right">
          16,140,852
        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: right">
          33,985,429
        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: right">
          27,878,531
        </td>
        <td>

        </td>
      </tr>
      <tr>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>
          &#160;
        </td>
      </tr>
      <tr>
        <td valign="top" style="padding-left: 0.0px; text-align: left">
          Operating expenses:
        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
      </tr>
      <tr>
        <td valign="top" style="padding-left: 20.0px; text-align: left">
          Cost of product revenue
        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: right">
          8,084,226
        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: right">
          6,655,804
        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: right">
          14,497,707
        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: right">
          12,260,366
        </td>
        <td>

        </td>
      </tr>
      <tr>
        <td valign="top" style="padding-left: 20.0px; text-align: left">
          Research &amp; development
        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: right">
          1,298,170
        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: right">
          1,574,155
        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: right">
          2,831,273
        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: right">
          3,106,820
        </td>
        <td>

        </td>
      </tr>
      <tr>
        <td valign="top" style="padding-bottom: 2.0px; padding-left: 20.0px; text-align: left">
          Selling, general &amp; administrative
        </td>
        <td>

        </td>
        <td style="border-bottom: solid black 1.0pt">
          &#160;
        </td>
        <td valign="bottom" style="border-bottom: solid black 1.0pt; padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: right">
          4,108,503
        </td>
        <td style="border-bottom: solid black 1.0pt">
          &#160;
        </td>
        <td>

        </td>
        <td style="border-bottom: solid black 1.0pt">
          &#160;
        </td>
        <td valign="bottom" style="border-bottom: solid black 1.0pt; padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: right">
          4,233,316
        </td>
        <td style="border-bottom: solid black 1.0pt">
          &#160;
        </td>
        <td>

        </td>
        <td style="border-bottom: solid black 1.0pt">
          &#160;
        </td>
        <td valign="bottom" style="border-bottom: solid black 1.0pt; padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: right">
          7,459,519
        </td>
        <td style="border-bottom: solid black 1.0pt">
          &#160;
        </td>
        <td>

        </td>
        <td style="border-bottom: solid black 1.0pt">
          &#160;
        </td>
        <td valign="bottom" style="border-bottom: solid black 1.0pt; padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: right">
          8,277,090
        </td>
        <td style="border-bottom: solid black 1.0pt">
          &#160;
        </td>
      </tr>
      <tr>
        <td valign="top" style="padding-bottom: 2.0px; padding-left: 0.0px; text-align: left">
          Total operating expenses
        </td>
        <td>

        </td>
        <td style="border-bottom: solid black 1.0pt">
          &#160;
        </td>
        <td valign="bottom" style="border-bottom: solid black 1.0pt; padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: right">
          13,490,899
        </td>
        <td style="border-bottom: solid black 1.0pt">
          &#160;
        </td>
        <td>

        </td>
        <td style="border-bottom: solid black 1.0pt">
          &#160;
        </td>
        <td valign="bottom" style="border-bottom: solid black 1.0pt; padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: right">
          12,463,275
        </td>
        <td style="border-bottom: solid black 1.0pt">
          &#160;
        </td>
        <td>

        </td>
        <td style="border-bottom: solid black 1.0pt">
          &#160;
        </td>
        <td valign="bottom" style="border-bottom: solid black 1.0pt; padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: right">
          24,788,499
        </td>
        <td style="border-bottom: solid black 1.0pt">
          &#160;
        </td>
        <td>

        </td>
        <td style="border-bottom: solid black 1.0pt">
          &#160;
        </td>
        <td valign="bottom" style="border-bottom: solid black 1.0pt; padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: right">
          23,644,276
        </td>
        <td style="border-bottom: solid black 1.0pt">
          &#160;
        </td>
      </tr>
      <tr>
        <td valign="top" style="padding-left: 0.0px; text-align: left">
          Income from operations
        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: right">
          6,133,870
        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: right">
          3,677,577
        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: right">
          9,196,930
        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: right">
          4,234,255
        </td>
        <td>

        </td>
      </tr>
      <tr>
        <td valign="top" style="padding-bottom: 2.0px; padding-left: 20.0px; text-align: left">
          Interest income (expense), net
        </td>
        <td>

        </td>
        <td style="border-bottom: solid black 1.0pt">
          &#160;
        </td>
        <td valign="bottom" style="border-bottom: solid black 1.0pt; padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: right">
          (49,129
        </td>
        <td valign="bottom" style="border-bottom: solid black 1.0pt; padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: left">
          )
        </td>
        <td>

        </td>
        <td style="border-bottom: solid black 1.0pt">
          &#160;
        </td>
        <td valign="bottom" style="border-bottom: solid black 1.0pt; padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: right">
          (45,281
        </td>
        <td valign="bottom" style="border-bottom: solid black 1.0pt; padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: left">
          )
        </td>
        <td>

        </td>
        <td style="border-bottom: solid black 1.0pt">
          &#160;
        </td>
        <td valign="bottom" style="border-bottom: solid black 1.0pt; padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: right">
          (100,332
        </td>
        <td valign="bottom" style="border-bottom: solid black 1.0pt; padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: left">
          )
        </td>
        <td>

        </td>
        <td style="border-bottom: solid black 1.0pt">
          &#160;
        </td>
        <td valign="bottom" style="border-bottom: solid black 1.0pt; padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: right">
          (86,202
        </td>
        <td valign="bottom" style="border-bottom: solid black 1.0pt; padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: left">
          )
        </td>
      </tr>
      <tr>
        <td valign="top" style="padding-left: 0.0px; text-align: left">
          Income before income taxes
        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: right">
          6,084,741
        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: right">
          3,632,296
        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: right">
          9,096,598
        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: right">
          4,148,053
        </td>
        <td>

        </td>
      </tr>
      <tr>
        <td valign="top" style="padding-bottom: 2.0px; padding-left: 20.0px; text-align: left">
          Provision for income taxes
        </td>
        <td>

        </td>
        <td style="border-bottom: solid black 1.0pt">
          &#160;
        </td>
        <td valign="bottom" style="border-bottom: solid black 1.0pt; padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: right">
          2,347,873
        </td>
        <td style="border-bottom: solid black 1.0pt">
          &#160;
        </td>
        <td>

        </td>
        <td style="border-bottom: solid black 1.0pt">
          &#160;
        </td>
        <td valign="bottom" style="border-bottom: solid black 1.0pt; padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: right">
          1,349,655
        </td>
        <td style="border-bottom: solid black 1.0pt">
          &#160;
        </td>
        <td>

        </td>
        <td style="border-bottom: solid black 1.0pt">
          &#160;
        </td>
        <td valign="bottom" style="border-bottom: solid black 1.0pt; padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: right">
          3,447,611
        </td>
        <td style="border-bottom: solid black 1.0pt">
          &#160;
        </td>
        <td>

        </td>
        <td style="border-bottom: solid black 1.0pt">
          &#160;
        </td>
        <td valign="bottom" style="border-bottom: solid black 1.0pt; padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: right">
          1,541,001
        </td>
        <td style="border-bottom: solid black 1.0pt">
          &#160;
        </td>
      </tr>
      <tr>
        <td valign="top" style="padding-bottom: 4.0px; padding-left: 0.0px; text-align: left">
          Net income
        </td>
        <td>

        </td>
        <td valign="bottom" style="border-bottom: double black 2.25pt; padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: right">
          $
        </td>
        <td valign="bottom" style="border-bottom: double black 2.25pt; padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: right">
          3,736,868
        </td>
        <td style="border-bottom: double black 2.25pt">
          &#160;
        </td>
        <td>

        </td>
        <td valign="bottom" style="border-bottom: double black 2.25pt; padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: right">
          $
        </td>
        <td valign="bottom" style="border-bottom: double black 2.25pt; padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: right">
          2,282,641
        </td>
        <td style="border-bottom: double black 2.25pt">
          &#160;
        </td>
        <td>

        </td>
        <td valign="bottom" style="border-bottom: double black 2.25pt; padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: right">
          $
        </td>
        <td valign="bottom" style="border-bottom: double black 2.25pt; padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: right">
          5,648,987
        </td>
        <td style="border-bottom: double black 2.25pt">
          &#160;
        </td>
        <td>

        </td>
        <td valign="bottom" style="border-bottom: double black 2.25pt; padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: right">
          $
        </td>
        <td valign="bottom" style="border-bottom: double black 2.25pt; padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: right">
          2,607,052
        </td>
        <td style="border-bottom: double black 2.25pt">
          &#160;
        </td>
      </tr>
      <tr>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>
          &#160;
        </td>
      </tr>
      <tr>
        <td valign="top" style="padding-left: 0.0px; text-align: left">
          Basic net income per share:
        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
      </tr>
      <tr>
        <td valign="top" style="padding-left: 20.0px; text-align: left">
          Net income
        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: right">
          $
        </td>
        <td valign="bottom" style="padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: right">
          0.28
        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: right">
          $
        </td>
        <td valign="bottom" style="padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: right">
          0.18
        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: right">
          $
        </td>
        <td valign="bottom" style="padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: right">
          0.43
        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: right">
          $
        </td>
        <td valign="bottom" style="padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: right">
          0.21
        </td>
        <td>

        </td>
      </tr>
      <tr>
        <td valign="top" style="padding-left: 20.0px; text-align: left">
          Basic weighted average common shares outstanding
        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: right">
          13,262,023
        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: right">
          12,725,216
        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: right">
          13,212,424
        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: right">
          12,707,143
        </td>
        <td>

        </td>
      </tr>
      <tr>
        <td valign="top" style="padding-left: 0.0px; text-align: left">
          Diluted net income per share:
        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
      </tr>
      <tr>
        <td valign="top" style="padding-left: 20.0px; text-align: left">
          Net income
        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: right">
          $
        </td>
        <td valign="bottom" style="padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: right">
          0.26
        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: right">
          $
        </td>
        <td valign="bottom" style="padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: right">
          0.17
        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: right">
          $
        </td>
        <td valign="bottom" style="padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: right">
          0.39
        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: right">
          $
        </td>
        <td valign="bottom" style="padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: right">
          0.19
        </td>
        <td>

        </td>
      </tr>
      <tr>
        <td valign="top" style="padding-left: 20.0px; text-align: left">
          Diluted weighted average common shares outstanding
        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: right">
          14,443,794
        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: right">
          13,739,836
        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: right">
          14,302,439
        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: right">
          13,741,337
        </td>
        <td>

        </td>
      </tr>
    </table>
    </div>
    <div style="margin-right: 0pt; margin-bottom: 10pt; width: 100%; margin-left: 0pt; text-indent: 0pt">
      <div>
        <div style="text-align: left">

        </div>
      </div>
      <div style="page-break-after: always">
        <div style="text-align: center">

        </div>
        <div style="text-align: center">
          <hr style="height: 1.5pt; color: black">

        </div>
      </div>
      <div>
        <div style="text-align: right">

        </div>
      </div>
    </div>
<div style="text-align:left">
    <table cellspacing="0" style="font-family: Times New Roman; font-size: 8pt; margin-bottom: 10.0px; width: 100%">
      <tr>
        <td>

        </td>
        <td>
          &#160;
        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>
          &#160;
        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
      </tr>
      <tr>
        <td colspan="9" valign="top" style="padding-left: 0.0px; text-align: center">
          <b>Anika Therapeutics, Inc. and Subsidiaries</b>
        </td>
      </tr>
      <tr>
        <td colspan="9" valign="top" style="padding-left: 0.0px; text-align: center">
          Condensed Consolidated Balance Sheets
        </td>
      </tr>
      <tr>
        <td colspan="9" valign="top" style="padding-left: 0.0px; text-align: center">
          (unaudited)
        </td>
      </tr>
      <tr>
        <td>

        </td>
        <td>

        </td>
        <td colspan="3" valign="top" style="padding-left: 0.0px; text-align: center">
          <b>June 30,</b>
        </td>
        <td>

        </td>
        <td colspan="3" valign="top" style="padding-left: 0.0px; text-align: center">
          <b>December 31,</b>
        </td>
      </tr>
      <tr>
        <td valign="top" style="padding-bottom: 2.0px; padding-left: 0.0px; text-align: center">
          <b>ASSETS</b>
        </td>
        <td>

        </td>
        <td colspan="3" valign="bottom" style="border-bottom: solid black 1.0pt; padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: center">
          <b>2012</b>
        </td>
        <td>

        </td>
        <td colspan="3" valign="bottom" style="border-bottom: solid black 1.0pt; padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: center">
          <b>2011</b>
        </td>
      </tr>
      <tr>
        <td valign="top" style="padding-left: 0.0px; text-align: left">
          Current assets:
        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
      </tr>
      <tr>
        <td valign="top" style="padding-left: 20.0px; text-align: left">
          Cash and cash equivalents
        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: right">
          $
        </td>
        <td valign="bottom" style="padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: right">
          37,909,608
        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: right">
          $
        </td>
        <td valign="bottom" style="padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: right">
          35,777,222
        </td>
        <td>

        </td>
      </tr>
      <tr>
        <td valign="top" style="padding-left: 20.0px; text-align: left">
          <p style="margin-top: 0px; margin-bottom: 0px">
            Accounts receivable, net of reserves of $457,300 and $334,473 at<br>June
            30, 2012 and December 31, 2011, respectively
          </p>
        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: right">
          17,694,097
        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: right">
          17,307,786
        </td>
        <td>

        </td>
      </tr>
      <tr>
        <td valign="top" style="padding-left: 20.0px; text-align: left">
          Inventories
        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: right">
          10,776,788
        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: right">
          7,302,483
        </td>
        <td>

        </td>
      </tr>
      <tr>
        <td valign="top" style="padding-left: 20.0px; text-align: left">
          Current portion deferred income taxes
        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: right">
          2,708,477
        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: right">
          1,918,926
        </td>
        <td>

        </td>
      </tr>
      <tr>
        <td valign="top" style="padding-bottom: 2.0px; padding-left: 20.0px; text-align: left">
          Prepaid expenses and other
        </td>
        <td>

        </td>
        <td style="border-bottom: solid black 1.0pt">
          &#160;
        </td>
        <td valign="bottom" style="border-bottom: solid black 1.0pt; padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: right">
          510,045
        </td>
        <td style="border-bottom: solid black 1.0pt">
          &#160;
        </td>
        <td>

        </td>
        <td style="border-bottom: solid black 1.0pt">
          &#160;
        </td>
        <td valign="bottom" style="border-bottom: solid black 1.0pt; padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: right">
          1,831,127
        </td>
        <td style="border-bottom: solid black 1.0pt">
          &#160;
        </td>
      </tr>
      <tr>
        <td valign="top" style="padding-left: 40.0px; text-align: left">
          Total current assets
        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: right">
          69,599,015
        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: right">
          64,137,544
        </td>
        <td>

        </td>
      </tr>
      <tr>
        <td valign="top" style="padding-left: 20.0px; text-align: left">
          Property and equipment, at cost
        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: right">
          51,920,745
        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: right">
          50,850,630
        </td>
        <td>

        </td>
      </tr>
      <tr>
        <td valign="top" style="padding-bottom: 2.0px; padding-left: 20.0px; text-align: left">
          Less: accumulated depreciation
        </td>
        <td>

        </td>
        <td style="border-bottom: solid black 1.0pt">
          &#160;
        </td>
        <td valign="bottom" style="border-bottom: solid black 1.0pt; padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: right">
          (15,499,638
        </td>
        <td valign="bottom" style="border-bottom: solid black 1.0pt; padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: left">
          )
        </td>
        <td>

        </td>
        <td style="border-bottom: solid black 1.0pt">
          &#160;
        </td>
        <td valign="bottom" style="border-bottom: solid black 1.0pt; padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: right">
          (14,380,752
        </td>
        <td valign="bottom" style="border-bottom: solid black 1.0pt; padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: left">
          )
        </td>
      </tr>
      <tr>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: right">
          36,421,107
        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: right">
          36,469,878
        </td>
        <td>

        </td>
      </tr>
      <tr>
        <td valign="top" style="padding-left: 0.0px; text-align: left">
          Long-term deposits and other
        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: right">
          221,485
        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: right">
          205,042
        </td>
        <td>

        </td>
      </tr>
      <tr>
        <td valign="top" style="padding-left: 0.0px; text-align: left">
          Intangible assets, net
        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: right">
          21,506,474
        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: right">
          23,148,563
        </td>
        <td>

        </td>
      </tr>
      <tr>
        <td valign="top" style="padding-bottom: 2.0px; padding-left: 0.0px; text-align: left">
          Goodwill
        </td>
        <td>

        </td>
        <td style="border-bottom: solid black 1.0pt">
          &#160;
        </td>
        <td valign="bottom" style="border-bottom: solid black 1.0pt; padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: right">
          8,627,518
        </td>
        <td style="border-bottom: solid black 1.0pt">
          &#160;
        </td>
        <td>

        </td>
        <td style="border-bottom: solid black 1.0pt">
          &#160;
        </td>
        <td valign="bottom" style="border-bottom: solid black 1.0pt; padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: right">
          8,883,407
        </td>
        <td style="border-bottom: solid black 1.0pt">
          &#160;
        </td>
      </tr>
      <tr>
        <td valign="top" style="padding-bottom: 4.0px; padding-left: 0.0px; text-align: left">
          Total Assets
        </td>
        <td>

        </td>
        <td valign="bottom" style="border-bottom: double black 2.25pt; padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: right">
          $
        </td>
        <td valign="bottom" style="border-bottom: double black 2.25pt; padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: right">
          136,375,599
        </td>
        <td style="border-bottom: double black 2.25pt">
          &#160;
        </td>
        <td>

        </td>
        <td valign="bottom" style="border-bottom: double black 2.25pt; padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: right">
          $
        </td>
        <td valign="bottom" style="border-bottom: double black 2.25pt; padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: right">
          132,844,434
        </td>
        <td style="border-bottom: double black 2.25pt">
          &#160;
        </td>
      </tr>
      <tr>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>
          &#160;
        </td>
      </tr>
      <tr>
        <td valign="top" style="padding-left: 0.0px; text-align: center">
          <b>LIABILITIES AND STOCKHOLDERS&#8217; EQUITY</b>
        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
      </tr>
      <tr>
        <td valign="top" style="padding-left: 0.0px; text-align: left">
          Current liabilities:
        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
      </tr>
      <tr>
        <td valign="top" style="padding-left: 20.0px; text-align: left">
          Accounts payable
        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: right">
          $
        </td>
        <td valign="bottom" style="padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: right">
          3,941,436
        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: right">
          $
        </td>
        <td valign="bottom" style="padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: right">
          4,299,680
        </td>
        <td>

        </td>
      </tr>
      <tr>
        <td valign="top" style="padding-left: 20.0px; text-align: left">
          Accrued expenses
        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: right">
          4,275,574
        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: right">
          5,321,594
        </td>
        <td>

        </td>
      </tr>
      <tr>
        <td valign="top" style="padding-left: 20.0px; text-align: left">
          Deferred revenue
        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: right">
          2,866,667
        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: right">
          2,866,667
        </td>
        <td>

        </td>
      </tr>
      <tr>
        <td valign="top" style="padding-left: 20.0px; text-align: left">
          Current portion of long-term debt
        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: right">
          1,600,000
        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: right">
          1,600,000
        </td>
        <td>

        </td>
      </tr>
      <tr>
        <td valign="top" style="padding-bottom: 2.0px; padding-left: 20.0px; text-align: left">
          Income taxes payable
        </td>
        <td>

        </td>
        <td style="border-bottom: solid black 1.0pt">
          &#160;
        </td>
        <td valign="bottom" style="border-bottom: solid black 1.0pt; padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: right">
          2,530,386
        </td>
        <td style="border-bottom: solid black 1.0pt">
          &#160;
        </td>
        <td>

        </td>
        <td style="border-bottom: solid black 1.0pt">
          &#160;
        </td>
        <td valign="bottom" style="border-bottom: solid black 1.0pt; padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: right">
          450,482
        </td>
        <td style="border-bottom: solid black 1.0pt">
          &#160;
        </td>
      </tr>
      <tr>
        <td valign="top" style="padding-bottom: 2.0px; padding-left: 40.0px; text-align: left">
          Total current liabilities
        </td>
        <td>

        </td>
        <td style="border-bottom: solid black 1.0pt">
          &#160;
        </td>
        <td valign="bottom" style="border-bottom: solid black 1.0pt; padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: right">
          15,214,063
        </td>
        <td style="border-bottom: solid black 1.0pt">
          &#160;
        </td>
        <td>

        </td>
        <td style="border-bottom: solid black 1.0pt">
          &#160;
        </td>
        <td valign="bottom" style="border-bottom: solid black 1.0pt; padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: right">
          14,538,423
        </td>
        <td style="border-bottom: solid black 1.0pt">
          &#160;
        </td>
      </tr>
      <tr>
        <td valign="top" style="padding-left: 0.0px; text-align: left">
          Other long-term liabilities
        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: right">
          1,535,140
        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: right">
          1,548,652
        </td>
        <td>

        </td>
      </tr>
      <tr>
        <td valign="top" style="padding-left: 0.0px; text-align: left">
          Long-term deferred revenue
        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: right">
          3,586,106
        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: right">
          5,019,440
        </td>
        <td>

        </td>
      </tr>
      <tr>
        <td valign="top" style="padding-left: 0.0px; text-align: left">
          Deferred tax liability
        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: right">
          6,491,837
        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: right">
          7,375,141
        </td>
        <td>

        </td>
      </tr>
      <tr>
        <td valign="top" style="padding-left: 0.0px; text-align: left">
          Long-term debt
        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: right">
          8,800,000
        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: right">
          9,600,000
        </td>
        <td>

        </td>
      </tr>
      <tr>
        <td valign="top" style="padding-left: 0.0px; text-align: left">
          Commitments and contingencies
        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: right">
          -
        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: right">
          -
        </td>
        <td>

        </td>
      </tr>
      <tr>
        <td valign="top" style="padding-left: 0.0px; text-align: left">
          Stockholders&#8217; equity:
        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
      </tr>
      <tr>
        <td valign="top" style="padding-left: 20.0px; text-align: left">
          <p style="margin-top: 0px; margin-bottom: 0px">
            Preferred stock, $.01 par value; 1,250,000 shares authorized, no<br>shares
            issued and outstanding at June 30, 2012<br>and December 31, 2011,
            respectively
          </p>
        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: right">
          -
        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: right">
          -
        </td>
        <td>

        </td>
      </tr>
      <tr>
        <td valign="top" style="padding-left: 20.0px; text-align: left">
          <p style="margin-top: 0px; margin-bottom: 0px">
            Common stock, $.01 par value; 30,000,000 shares authorized,<br>13,765,996
            and 13,630,607 shares issued and outstanding at
          </p>
          <p style="margin-top: 0px; margin-bottom: 0px">
            June 30, 2012<br>and December 31, 2011, respectively
          </p>
        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: right">
          137,659
        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: right">
          136,305
        </td>
        <td>

        </td>
      </tr>
      <tr>
        <td valign="top" style="padding-left: 20.0px; text-align: left">
          Additional paid-in-capital
        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: right">
          64,620,510
        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: right">
          63,441,433
        </td>
        <td>

        </td>
      </tr>
      <tr>
        <td valign="top" style="padding-left: 20.0px; text-align: left">
          Accumulated currency translation adjustment
        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: right">
          (3,910,924
        </td>
        <td valign="bottom" style="padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: left">
          )
        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: right">
          (3,067,181
        </td>
        <td valign="bottom" style="padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: left">
          )
        </td>
      </tr>
      <tr>
        <td valign="top" style="padding-bottom: 2.0px; padding-left: 20.0px; text-align: left">
          Retained earnings
        </td>
        <td>

        </td>
        <td style="border-bottom: solid black 1.0pt">
          &#160;
        </td>
        <td valign="bottom" style="border-bottom: solid black 1.0pt; padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: right">
          39,901,208
        </td>
        <td style="border-bottom: solid black 1.0pt">
          &#160;
        </td>
        <td>

        </td>
        <td style="border-bottom: solid black 1.0pt">
          &#160;
        </td>
        <td valign="bottom" style="border-bottom: solid black 1.0pt; padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: right">
          34,252,221
        </td>
        <td style="border-bottom: solid black 1.0pt">
          &#160;
        </td>
      </tr>
      <tr>
        <td valign="top" style="padding-bottom: 2.0px; padding-left: 40.0px; text-align: left">
          Total stockholders&#8217; equity
        </td>
        <td>

        </td>
        <td style="border-bottom: solid black 1.0pt">
          &#160;
        </td>
        <td valign="bottom" style="border-bottom: solid black 1.0pt; padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: right">
          100,748,453
        </td>
        <td style="border-bottom: solid black 1.0pt">
          &#160;
        </td>
        <td>

        </td>
        <td style="border-bottom: solid black 1.0pt">
          &#160;
        </td>
        <td valign="bottom" style="border-bottom: solid black 1.0pt; padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: right">
          94,762,778
        </td>
        <td style="border-bottom: solid black 1.0pt">
          &#160;
        </td>
      </tr>
      <tr>
        <td valign="top" style="padding-bottom: 4.0px; padding-left: 0.0px; text-align: left">
          Total Liabilities and Stockholders&#8217; Equity
        </td>
        <td>

        </td>
        <td valign="bottom" style="border-bottom: double black 2.25pt; padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: right">
          $
        </td>
        <td valign="bottom" style="border-bottom: double black 2.25pt; padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: right">
          136,375,599
        </td>
        <td style="border-bottom: double black 2.25pt">
          &#160;
        </td>
        <td>

        </td>
        <td valign="bottom" style="border-bottom: double black 2.25pt; padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: right">
          $
        </td>
        <td valign="bottom" style="border-bottom: double black 2.25pt; padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: right">
          132,844,434
        </td>
        <td style="border-bottom: double black 2.25pt">
          &#160;
        </td>
      </tr>
    </table>
    </div>
    <div style="margin-right: 0pt; margin-bottom: 10pt; width: 100%; margin-left: 0pt; text-indent: 0pt">
      <div>
        <div style="text-align: left">

        </div>
      </div>
      <div style="page-break-after: always">
        <div style="text-align: center">

        </div>
        <div style="text-align: center">
          <hr style="height: 1.5pt; color: black">

        </div>
      </div>
      <div>
        <div style="text-align: right">

        </div>
      </div>
    </div>
<div style="text-align:left">
    <table cellspacing="0" style="font-family: Times New Roman; font-size: 8pt; margin-bottom: 10.0px; width: 100%">
      <tr>
        <td colspan="12">
          &#160;
        </td>
      </tr>
      <tr>
        <td colspan="12" valign="top" style="padding-left: 0.0px; text-align: center">
          <b>Anika Therapeutics, Inc. and Subsidiaries</b>
        </td>
      </tr>
      <tr>
        <td colspan="12" valign="top" style="padding-left: 0.0px; text-align: center">
          Supplemental Financial Data
        </td>
      </tr>
      <tr>
        <td colspan="12" valign="top" style="padding-left: 0.0px; text-align: center">
          Revenue by Product Line and Product Gross Margin
        </td>
      </tr>
      <tr>
        <td>

        </td>
        <td>
          &#160;
        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>
          &#160;
        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>
          &#160;
        </td>
        <td>

        </td>
        <td>

        </td>
      </tr>
      <tr>
        <td>

        </td>
        <td>

        </td>
        <td colspan="10" valign="top" style="border-bottom: solid black 1.0pt; padding-left: 0.0px; text-align: center">
          <b>Three Months Ended June 30,</b>
        </td>
      </tr>
      <tr>
        <td>

        </td>
        <td>

        </td>
        <td colspan="3" valign="bottom" style="border-bottom: solid black 1.0pt; padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: center">
          <b>2012</b>
        </td>
        <td valign="bottom" style="padding-bottom: 2.0px; padding-left: 0.0px; text-align: center">
          <p style="margin-top: 0px; margin-bottom: 0px">
            &#160;
          </p>
        </td>
        <td colspan="3" valign="bottom" style="border-bottom: solid black 1.0pt; padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: center">
          <p style="margin-top: 0px; margin-bottom: 0px">
            <b>2011</b>
          </p>
        </td>
        <td>

        </td>
        <td colspan="2" valign="bottom" style="border-bottom: solid black 1.0pt; padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: center">
          <b>%</b>
        </td>
      </tr>
      <tr>
        <td valign="top" style="padding-left: 20.0px; text-align: left">
          Orthobiologics
        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: right">
          $
        </td>
        <td valign="bottom" style="padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: right">
          10,903,364
        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: right">
          $
        </td>
        <td valign="bottom" style="padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: right">
          9,763,597
        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: right">
          12
        </td>
        <td valign="bottom" style="padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: left">
          %
        </td>
      </tr>
      <tr>
        <td valign="top" style="padding-left: 20.0px; text-align: left">
          Dermal
        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: right">
          155,735
        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: right">
          799,605
        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: right">
          -81
        </td>
        <td valign="bottom" style="padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: left">
          %
        </td>
      </tr>
      <tr>
        <td valign="top" style="padding-left: 20.0px; text-align: left">
          Ophthalmic
        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: right">
          5,299,732
        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: right">
          2,584,820
        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: right">
          105
        </td>
        <td valign="bottom" style="padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: left">
          %
        </td>
      </tr>
      <tr>
        <td valign="top" style="padding-left: 20.0px; text-align: left">
          Surgical
        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: right">
          1,464,505
        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: right">
          1,566,026
        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: right">
          -6
        </td>
        <td valign="bottom" style="padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: left">
          %
        </td>
      </tr>
      <tr>
        <td valign="top" style="padding-bottom: 2.0px; padding-left: 20.0px; text-align: left">
          Veterinary
        </td>
        <td>

        </td>
        <td style="border-bottom: solid black 1.0pt">
          &#160;
        </td>
        <td valign="bottom" style="border-bottom: solid black 1.0pt; padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: right">
          1,058,941
        </td>
        <td style="border-bottom: solid black 1.0pt">
          &#160;
        </td>
        <td>

        </td>
        <td style="border-bottom: solid black 1.0pt">
          &#160;
        </td>
        <td valign="bottom" style="border-bottom: solid black 1.0pt; padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: right">
          700,633
        </td>
        <td style="border-bottom: solid black 1.0pt">
          &#160;
        </td>
        <td>

        </td>
        <td valign="bottom" style="border-bottom: solid black 1.0pt; padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: right">
          51
        </td>
        <td valign="bottom" style="border-bottom: solid black 1.0pt; padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: left">
          %
        </td>
      </tr>
      <tr>
        <td valign="top" style="padding-bottom: 4.0px; padding-left: 20.0px; text-align: left">
          Total Product Revenue
        </td>
        <td>

        </td>
        <td valign="bottom" style="border-bottom: double black 2.25pt; padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: right">
          $
        </td>
        <td valign="bottom" style="border-bottom: double black 2.25pt; padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: right">
          18,882,277
        </td>
        <td style="border-bottom: double black 2.25pt">
          &#160;
        </td>
        <td>

        </td>
        <td valign="bottom" style="border-bottom: double black 2.25pt; padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: right">
          $
        </td>
        <td valign="bottom" style="border-bottom: double black 2.25pt; padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: right">
          15,414,681
        </td>
        <td style="border-bottom: double black 2.25pt">
          &#160;
        </td>
        <td>

        </td>
        <td valign="bottom" style="border-bottom: double black 2.25pt; padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: right">
          22
        </td>
        <td valign="bottom" style="border-bottom: double black 2.25pt; padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: left">
          %
        </td>
      </tr>
      <tr>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>
          &#160;
        </td>
      </tr>
      <tr>
        <td valign="top" style="padding-left: 0.0px; text-align: left">
          Product gross profit
        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: right">
          $
        </td>
        <td valign="bottom" style="padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: right">
          10,798,051
        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: right">
          $
        </td>
        <td valign="bottom" style="padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: right">
          8,758,877
        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
      </tr>
      <tr>
        <td valign="top" style="padding-left: 0.0px; text-align: left">
          Product gross margin
        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: right">
          57.2
        </td>
        <td valign="bottom" style="padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: left">
          %
        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: right">
          56.8
        </td>
        <td valign="bottom" style="padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: left">
          %
        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
      </tr>
      <tr>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>
          &#160;
        </td>
      </tr>
      <tr>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>
          &#160;
        </td>
      </tr>
      <tr>
        <td>

        </td>
        <td>

        </td>
        <td colspan="10" valign="top" style="border-bottom: solid black 1.0pt; padding-left: 0.0px; text-align: center">
          <b>Six Months Ended June 30,</b>
        </td>
      </tr>
      <tr>
        <td>

        </td>
        <td>

        </td>
        <td colspan="3" valign="bottom" style="border-bottom: solid black 1.0pt; padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: center">
          <b>2012</b>
        </td>
        <td valign="bottom" style="padding-bottom: 2.0px; padding-left: 0.0px; text-align: center">
          <p style="margin-top: 0px; margin-bottom: 0px">
            &#160;
          </p>
        </td>
        <td colspan="3" valign="bottom" style="border-bottom: solid black 1.0pt; padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: center">
          <p style="margin-top: 0px; margin-bottom: 0px">
            <b>2011</b>
          </p>
        </td>
        <td>

        </td>
        <td colspan="2" valign="bottom" style="border-bottom: solid black 1.0pt; padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: center">
          <b>%</b>
        </td>
      </tr>
      <tr>
        <td valign="top" style="padding-left: 20.0px; text-align: left">
          Orthobiologics
        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: right">
          $
        </td>
        <td valign="bottom" style="padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: right">
          21,020,209
        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: right">
          $
        </td>
        <td valign="bottom" style="padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: right">
          17,799,893
        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: right">
          18
        </td>
        <td valign="bottom" style="padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: left">
          %
        </td>
      </tr>
      <tr>
        <td valign="top" style="padding-left: 20.0px; text-align: left">
          Dermal
        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: right">
          657,051
        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: right">
          1,388,759
        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: right">
          -53
        </td>
        <td valign="bottom" style="padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: left">
          %
        </td>
      </tr>
      <tr>
        <td valign="top" style="padding-left: 20.0px; text-align: left">
          Ophthalmic
        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: right">
          6,623,726
        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: right">
          3,482,629
        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: right">
          90
        </td>
        <td valign="bottom" style="padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: left">
          %
        </td>
      </tr>
      <tr>
        <td valign="top" style="padding-left: 20.0px; text-align: left">
          Surgical
        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: right">
          2,448,133
        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: right">
          2,679,755
        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: right">
          -9
        </td>
        <td valign="bottom" style="padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: left">
          %
        </td>
      </tr>
      <tr>
        <td valign="top" style="padding-bottom: 2.0px; padding-left: 20.0px; text-align: left">
          Veterinary
        </td>
        <td>

        </td>
        <td style="border-bottom: solid black 1.0pt">
          &#160;
        </td>
        <td valign="bottom" style="border-bottom: solid black 1.0pt; padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: right">
          1,746,486
        </td>
        <td style="border-bottom: solid black 1.0pt">
          &#160;
        </td>
        <td>

        </td>
        <td style="border-bottom: solid black 1.0pt">
          &#160;
        </td>
        <td valign="bottom" style="border-bottom: solid black 1.0pt; padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: right">
          1,123,804
        </td>
        <td style="border-bottom: solid black 1.0pt">
          &#160;
        </td>
        <td>

        </td>
        <td valign="bottom" style="border-bottom: solid black 1.0pt; padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: right">
          55
        </td>
        <td valign="bottom" style="border-bottom: solid black 1.0pt; padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: left">
          %
        </td>
      </tr>
      <tr>
        <td valign="top" style="padding-bottom: 4.0px; padding-left: 20.0px; text-align: left">
          Total Product Revenue
        </td>
        <td>

        </td>
        <td valign="bottom" style="border-bottom: double black 2.25pt; padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: right">
          $
        </td>
        <td valign="bottom" style="border-bottom: double black 2.25pt; padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: right">
          32,495,605
        </td>
        <td style="border-bottom: double black 2.25pt">
          &#160;
        </td>
        <td>

        </td>
        <td valign="bottom" style="border-bottom: double black 2.25pt; padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: right">
          $
        </td>
        <td valign="bottom" style="border-bottom: double black 2.25pt; padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: right">
          26,474,840
        </td>
        <td style="border-bottom: double black 2.25pt">
          &#160;
        </td>
        <td>

        </td>
        <td valign="bottom" style="border-bottom: double black 2.25pt; padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: right">
          23
        </td>
        <td valign="bottom" style="border-bottom: double black 2.25pt; padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: left">
          %
        </td>
      </tr>
      <tr>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>
          &#160;
        </td>
      </tr>
      <tr>
        <td valign="top" style="padding-left: 0.0px; text-align: left">
          Product gross profit
        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: right">
          $
        </td>
        <td valign="bottom" style="padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: right">
          17,997,898
        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: right">
          $
        </td>
        <td valign="bottom" style="padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: right">
          14,214,474
        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
      </tr>
      <tr>
        <td valign="top" style="padding-left: 0.0px; text-align: left">
          Product gross margin
        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: right">
          55.4
        </td>
        <td valign="bottom" style="padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: left">
          %
        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: right">
          53.7
        </td>
        <td valign="bottom" style="padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: left">
          %
        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
      </tr>
      <tr>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>
          &#160;
        </td>
      </tr>
      <tr>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>
          &#160;
        </td>
      </tr>
      <tr>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>
          &#160;
        </td>
      </tr>
      <tr>
        <td colspan="12" valign="top" style="padding-left: 0.0px; text-align: center">
          <b>Anika Therapeutics, Inc. and Subsidiaries</b>
        </td>
      </tr>
      <tr>
        <td colspan="12" valign="top" style="padding-left: 0.0px; text-align: center">
          Supplemental Financial Data
        </td>
      </tr>
      <tr>
        <td colspan="12" valign="top" style="padding-left: 0.0px; text-align: center">
          Revenue by Geographic Region
        </td>
      </tr>
      <tr>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>
          &#160;
        </td>
      </tr>
      <tr>
        <td>

        </td>
        <td>

        </td>
        <td colspan="10" valign="top" style="border-bottom: solid black 1.0pt; padding-left: 0.0px; text-align: center">
          <b>Three Months Ended June 30,</b>
        </td>
      </tr>
      <tr>
        <td>

        </td>
        <td>

        </td>
        <td colspan="3" valign="bottom" style="border-bottom: solid black 1.0pt; padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: center">
          <b>2012</b>
        </td>
        <td>

        </td>
        <td colspan="3" valign="bottom" style="border-bottom: solid black 1.0pt; padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: center">
          <b>2011</b>
        </td>
        <td>

        </td>
        <td colspan="2" valign="bottom" style="border-bottom: solid black 1.0pt; padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: center">
          <b>%</b>
        </td>
      </tr>
      <tr>
        <td valign="top" style="padding-left: 0.0px; text-align: left">
          <b>Geographic Location:</b>
        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
      </tr>
      <tr>
        <td valign="top" style="padding-left: 20.0px; text-align: left">
          United States
        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: right">
          $
        </td>
        <td valign="bottom" style="padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: right">
          16,011,667
        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: right">
          $
        </td>
        <td valign="bottom" style="padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: right">
          11,594,988
        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: right">
          38
        </td>
        <td valign="bottom" style="padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: left">
          %
        </td>
      </tr>
      <tr>
        <td valign="top" style="padding-left: 20.0px; text-align: left">
          Europe
        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: right">
          1,521,552
        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: right">
          2,604,021
        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: right">
          -42
        </td>
        <td valign="bottom" style="padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: left">
          %
        </td>
      </tr>
      <tr>
        <td valign="top" style="padding-bottom: 2.0px; padding-left: 20.0px; text-align: left">
          Other
        </td>
        <td>

        </td>
        <td style="border-bottom: solid black 1.0pt">
          &#160;
        </td>
        <td valign="bottom" style="border-bottom: solid black 1.0pt; padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: right">
          1,349,058
        </td>
        <td style="border-bottom: solid black 1.0pt">
          &#160;
        </td>
        <td>

        </td>
        <td style="border-bottom: solid black 1.0pt">
          &#160;
        </td>
        <td valign="bottom" style="border-bottom: solid black 1.0pt; padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: right">
          1,215,672
        </td>
        <td style="border-bottom: solid black 1.0pt">
          &#160;
        </td>
        <td>

        </td>
        <td valign="bottom" style="border-bottom: solid black 1.0pt; padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: right">
          11
        </td>
        <td valign="bottom" style="border-bottom: solid black 1.0pt; padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: left">
          %
        </td>
      </tr>
      <tr>
        <td valign="top" style="padding-bottom: 4.0px; padding-left: 40.0px; text-align: left">
          Total
        </td>
        <td>

        </td>
        <td valign="bottom" style="border-bottom: double black 2.25pt; padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: right">
          $
        </td>
        <td valign="bottom" style="border-bottom: double black 2.25pt; padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: right">
          18,882,277
        </td>
        <td style="border-bottom: double black 2.25pt">
          &#160;
        </td>
        <td>

        </td>
        <td valign="bottom" style="border-bottom: double black 2.25pt; padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: right">
          $
        </td>
        <td valign="bottom" style="border-bottom: double black 2.25pt; padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: right">
          15,414,681
        </td>
        <td style="border-bottom: double black 2.25pt">
          &#160;
        </td>
        <td>

        </td>
        <td valign="bottom" style="border-bottom: double black 2.25pt; padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: right">
          22
        </td>
        <td valign="bottom" style="border-bottom: double black 2.25pt; padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: left">
          %
        </td>
      </tr>
      <tr>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>
          &#160;
        </td>
      </tr>
      <tr>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>
          &#160;
        </td>
      </tr>
      <tr>
        <td>

        </td>
        <td>

        </td>
        <td colspan="10" valign="top" style="border-bottom: solid black 1.0pt; padding-left: 0.0px; text-align: center">
          <b>Six Months Ended June 30,</b>
        </td>
      </tr>
      <tr>
        <td>

        </td>
        <td>

        </td>
        <td colspan="3" valign="bottom" style="border-bottom: solid black 1.0pt; padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: center">
          <b>2012</b>
        </td>
        <td>

        </td>
        <td colspan="3" valign="bottom" style="border-bottom: solid black 1.0pt; padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: center">
          <b>2011</b>
        </td>
        <td>

        </td>
        <td colspan="2" valign="bottom" style="border-bottom: solid black 1.0pt; padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: center">
          <b>%</b>
        </td>
      </tr>
      <tr>
        <td valign="top" style="padding-left: 0.0px; text-align: left">
          <b>Geographic Location:</b>
        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
      </tr>
      <tr>
        <td valign="top" style="padding-left: 20.0px; text-align: left">
          United States
        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: right">
          $
        </td>
        <td valign="bottom" style="padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: right">
          26,401,712
        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: right">
          $
        </td>
        <td valign="bottom" style="padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: right">
          19,938,102
        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: right">
          32
        </td>
        <td valign="bottom" style="padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: left">
          %
        </td>
      </tr>
      <tr>
        <td valign="top" style="padding-left: 20.0px; text-align: left">
          Europe
        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: right">
          3,677,281
        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: right">
          4,637,219
        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: right">
          -21
        </td>
        <td valign="bottom" style="padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: left">
          %
        </td>
      </tr>
      <tr>
        <td valign="top" style="padding-bottom: 2.0px; padding-left: 20.0px; text-align: left">
          Other
        </td>
        <td>

        </td>
        <td style="border-bottom: solid black 1.0pt">
          &#160;
        </td>
        <td valign="bottom" style="border-bottom: solid black 1.0pt; padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: right">
          2,416,612
        </td>
        <td style="border-bottom: solid black 1.0pt">
          &#160;
        </td>
        <td>

        </td>
        <td style="border-bottom: solid black 1.0pt">
          &#160;
        </td>
        <td valign="bottom" style="border-bottom: solid black 1.0pt; padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: right">
          1,899,519
        </td>
        <td style="border-bottom: solid black 1.0pt">
          &#160;
        </td>
        <td>

        </td>
        <td valign="bottom" style="border-bottom: solid black 1.0pt; padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: right">
          27
        </td>
        <td valign="bottom" style="border-bottom: solid black 1.0pt; padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: left">
          %
        </td>
      </tr>
      <tr>
        <td valign="top" style="padding-bottom: 4.0px; padding-left: 40.0px; text-align: left">
          Total
        </td>
        <td>

        </td>
        <td valign="bottom" style="border-bottom: double black 2.25pt; padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: right">
          $
        </td>
        <td valign="bottom" style="border-bottom: double black 2.25pt; padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: right">
          32,495,605
        </td>
        <td style="border-bottom: double black 2.25pt">
          &#160;
        </td>
        <td>

        </td>
        <td valign="bottom" style="border-bottom: double black 2.25pt; padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: right">
          $
        </td>
        <td valign="bottom" style="border-bottom: double black 2.25pt; padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: right">
          26,474,840
        </td>
        <td style="border-bottom: double black 2.25pt">
          &#160;
        </td>
        <td>

        </td>
        <td valign="bottom" style="border-bottom: double black 2.25pt; padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: right">
          23
        </td>
        <td valign="bottom" style="border-bottom: double black 2.25pt; padding-left: 0.0px; padding-right: 0.0px; white-space: nowrap; text-align: left">
          %
        </td>
      </tr>
    </table>
    </div>
    <p>

    </p>
    <p>
      CONTACT:<br>Anika Therapeutics, Inc.<br>Charles H. Sherwood, Ph.D.,
      781-457-9000<br>CEO<br>or<br>Kevin W. Quinlan, 781-457-9000<br>CFO
    </p>
  </body>
</html>
</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
