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Consolidated Statements of Operations and Comprehensive Income (USD $) | 12 Months Ended
--- | ---
Dec. 31, 2012 | Dec. 31, 2011 | Dec. 31, 2010
Product revenue | $ 68,010,169 | $ 61,956,386 | $ 52,735,730
Licensing, milestone and contract revenue | 3,348,336 | 2,822,249 | 2,820,864
Total revenue | 71,358,505 | 64,778,635 | 55,556,594
Operating expenses: |  |  |
Cost of product revenue | 28,988,621 | 26,783,738 | 23,826,604
Research & development | 5,388,036 | 6,168,937 | 6,874,633
Selling, general & administrative | 14,728,662 | 17,858,558 | 17,317,671
Restructuring charges | 2,537,988 |  |
Total operating expenses | 51,643,307 | 50,811,233 | 48,018,908
Income from operations | 19,715,198 | 13,967,402 | 7,537,686
Interest income (expense), net | (187,777) | (182,388) | (194,620)
Income before income taxes | 19,527,421 | 13,785,014 | 7,343,066
Provision for income taxes | 7,769,961 | 5,318,334 | 3,027,071
Net income | 11,757,460 | 8,466,680 | 4,315,995
Basic net income per share: |  |  |
Net income | $ 0.89 | $ 0.65 | $ 0.34
Basic weighted average common shares outstanding | 13,260,739 | 13,064,051 | 12,624,495
Diluted net income per share: |  |  |
Net income | $ 0.82 | $ 0.62 | $ 0.32
Diluted weighted average common shares outstanding | 14,344,577 | 13,747,813 | 13,646,533
Net income | 11,757,460 | 8,466,680 | 4,315,995
Other comprehensive income (loss) |  |  |
Foreign currency translation adjustment | 412,551 | (519,405) | (2,547,776)
Comprehensive income | $ 12,170,011 | $ 7,947,275 | $ 1,768,219

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- Definition The aggregate total costs related to selling a firm's product and services, as well as all other general and administrative expenses. Direct selling expenses (for example, credit, warranty, and advertising) are expenses that can be directly linked to the sale of specific products. Indirect selling expenses are expenses that cannot be directly linked to the sale of specific products, for example telephone expenses, Internet, and postal charges. General and administrative expenses include salaries of non-sales personnel, rent, utilities, communication, etc. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher AICPA -Name Accounting Research Bulletin (ARB) -Number 43 -Paragraph 5A -Chapter 4 -LegacyDoc This reference is SUPERSEDED by the Accounting Standards Codification effective for interim and annual periods ending after September 15, 2009. This reference is included to help users transition from the previous accounting hierarchy and will be removed from future versions of this taxonomy. Reference 2: http://www.xbrl.org/2003/role/presentationRef -Publisher SEC -Name Regulation S-X (SX) -Number 210 -Section 03 -Paragraph 4 -Article 5 Reference 3: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 225 -SubTopic 10 -Section S99 -Paragraph 2 -Subparagraph (SX 210.5-03.4) -URI http://asc.fasb.org/extlink&oid=6880815&loc=d3e20235-122688 Reference 4: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 330 -SubTopic 10 -Section 30 -Paragraph 8 -URI http://asc.fasb.org/extlink&oid=6386349&loc=d3e3636-108311 + Details
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- Definition The average number of shares or units issued and outstanding that are used in calculating diluted EPS or earnings per unit (EPU), determined based on the timing of issuance of shares or units in the period. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Statement of Financial Accounting Standard (FAS) -Number 128 -Paragraph 40 -Subparagraph a -LegacyDoc This reference is SUPERSEDED by the Accounting Standards Codification effective for interim and annual periods ending after September 15, 2009. This reference is included to help users transition from the previous accounting hierarchy and will be removed from future versions of this taxonomy. Reference 2: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Statement of Financial Accounting Standard (FAS) -Number 128 -Paragraph 8 -LegacyDoc This reference is SUPERSEDED by the Accounting Standards Codification effective for interim and annual periods ending after September 15, 2009. This reference is included to help users transition from the previous accounting hierarchy and will be removed from future versions of this taxonomy. Reference 3: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 260 -SubTopic 10 -Section 50 -Paragraph 1 -Subparagraph (a) -URI http://asc.fasb.org/extlink&oid=6371337&loc=d3e3550-109257 Reference 4: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Emerging Issues Task Force (EITF) -Number 07-4 -Paragraph 4 -LegacyDoc This reference is SUPERSEDED by the Accounting Standards Codification effective for interim and annual periods ending after September 15, 2009. This reference is included to help users transition from the previous accounting hierarchy and will be removed from future versions of this taxonomy. Reference 5: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 260 -SubTopic 10 -Section 45 -Paragraph 16 -URI http://asc.fasb.org/extlink&oid=7655603&loc=d3e1505-109256 + Details
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