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Commitments and Contingencies - Additional Information (Detail) (USD $) | 12 Months Ended | 1 Months Ended |  | 1 Months Ended
--- | --- | --- | --- | ---
Dec. 31, 2012 | Dec. 31, 2011 | Dec. 31, 2010 | May 01, 2007 Bedford, Massachusetts | Dec. 31, 2011 Bedford, Massachusetts sqft | May 01, 2007 Bedford, Massachusetts Maximum Phase | Dec. 30, 2009 AbanoTerme, Italy sqft
Commitments and Contingencies Disclosure [Line Items] |  |  |  |  |  |  |
Area of leased space |  |  |  |  | 134,000 |  | 26,000
Lease term |  |  |  | 10 years 6 months |  |  | 6 years
Number of periods up to which lease term can be extended |  |  |  |  |  | 4 |
Lease and rental expense | $ 2,486,849 | $ 3,479,632 | $ 2,888,277 |  |  |  |

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- Details
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- Definition Facility Leased + References No definition available. + Details
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