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Revenue by Product Group, by Significant Customer and by Geographic Region; Geographic Information | 12 Months Ended
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Dec. 31, 2012
Revenue by Product Group, by Significant Customer and by Geographic Region; Geographic Information | 13. Revenue by Product Group, by Significant Customer and by Geographic Region; Geographic Information Product revenue by product group is as follows:
|  | Year Ended December 31, |
|  | 2012 |  |  | 2011 |  |  | 2010 |
|  | Revenue |  |  | Percentage of Product Revenue |  |  | Revenue |  |  | Percentage of Product Revenue |  |  | Revenue |  |  | Percentage of Product Revenue |
Orthobiologics |  | $ | 49,954,112 |  |  |  | 73.5 | % |  | $ | 39,858,139 |  |  |  | 64.3 | % |  | $ | 30,741,305 |  |  |  | 58.3 | %
Dermal |  |  | 1,384,403 |  |  |  | 2.0 | % |  |  | 3,681,166 |  |  |  | 5.9 | % |  |  | 3,564,616 |  |  |  | 6.8 | %
Surgical |  |  | 5,022,456 |  |  |  | 7.4 | % |  |  | 4,976,261 |  |  |  | 8.1 | % |  |  | 3,883,444 |  |  |  | 7.3 | %
Ophthalmic |  |  | 8,784,011 |  |  |  | 12.9 | % |  |  | 10,963,822 |  |  |  | 17.7 | % |  |  | 11,971,787 |  |  |  | 22.7 | %
Veterinary |  |  | 2,865,187 |  |  |  | 4.2 | % |  |  | 2,476,998 |  |  |  | 4.0 | % |  |  | 2,574,578 |  |  |  | 4.9 | %
|  | $ | 68,010,169 |  |  |  | 100.0 | % |  | $ | 61,956,386 |  |  |  | 100.0 | % |  | $ | 52,735,730 |  |  |  | 100.0 | %
Product revenue by significant customers as a percent of product revenues is as follows:
|  | Percent of Product Revenue
|  | Year Ended December 31,
|  | 2012 |  | 2011 |  | 2010
DePuy Mitek |  | 61.2% |  | 47.1% |  | 42.7%
Bausch & Lomb Inc. |  | 11.4% |  | 15.8% |  | 21.2%
Boehringer |  | 4.2% |  | 4.0% |  | 4.9%
Medtronic |  | 3.1% |  | 5.6% |  | 10.2%
Rivex Pharma |  | 2.0% |  | 1.3% |  | 1.5%
|  | 81.9% |  | 73.8% |  | 80.5%
Revenues by geographic location in total and as a percentage of total revenues are as follows:
|  | Year Ended December 31, |
|  | 2012 |  |  | 2011 |  |  | 2010 |
|  | Revenue |  |  | Percentage of Total Revenue |  | Revenue |  |  | Percentage of Total Revenue |  | Revenue |  |  | Percentage of Total Revenue |
United States |  | $ | 57,904,290 |  |  |  | 81.1 | % |  | $ | 48,366,140 |  |  |  | 74.7 | % |  | $ | 38,313,594 |  |  |  | 69.0 | %
Europe |  |  | 6,267,830 |  |  |  | 8.8 | % |  |  | 10,988,664 |  |  |  | 16.9 | % |  |  | 12,976,985 |  |  |  | 23.3 | %
Other |  |  | 7,186,385 |  |  |  | 10.1 | % |  |  | 5,423,831 |  |  |  | 8.4 | % |  |  | 4,266,015 |  |  |  | 7.7 | %
Total |  | $ | 71,358,505 |  |  |  | 100.0 | % |  | $ | 64,778,635 |  |  |  | 100.0 | % |  | $ | 55,556,594 |  |  |  | 100.0 | %
The Company recorded licensing, milestone and contract revenue of $3,348,336, $2,822,249 and $2,820,864 for the years ended December 31, 2012, 2011, and 2010, respectively. Substantially all licensing, milestone and contract revenue was derived in the United States for each year presented. Net long-lived assets, consisting of net property and equipment, are subject to geographic risks because they are generally difficult to move and to effectively utilize in another geographic area in a reasonable time period and because they are relatively illiquid. Net tangible long-lived assets by principal geographic areas were as follows:
|  | Years Ended December 31, |
|  | 2012 |  |  | 2011 |
United States |  | $ | 33,792,325 |  |  | $ | 34,565,770 |
Italy |  |  | 1,320,656 |  |  |  | 1,904,108 |
Total |  | $ | 35,112,981 |  |  | $ | 36,469,878 |

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