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Revenue by Product Group, by Significant Customer and by Geographic Region; Geographic Information
 12 Months Ended
Dec. 31, 2012
Revenue by Product Group, by Significant Customer and by Geographic Region; Geographic Information
13. Revenue by Product Group, by Significant Customer and by Geographic Region; Geographic Information
 
Product revenue by product group is as follows:
 
   
Year Ended December 31,
  
   
2012
    
2011
    
2010
  
   
Revenue
    
Percentage of Product Revenue
    
Revenue
    
Percentage of Product Revenue
    
Revenue
    
Percentage of Product Revenue
  
Orthobiologics
   $ 49,954,112       73.5 %   $ 39,858,139       64.3 %   $ 30,741,305       58.3 %
Dermal
     1,384,403       2.0 %     3,681,166       5.9 %     3,564,616       6.8 %
Surgical
     5,022,456       7.4 %     4,976,261       8.1 %     3,883,444       7.3 %
Ophthalmic
     8,784,011       12.9 %     10,963,822       17.7 %     11,971,787       22.7 %
Veterinary
     2,865,187       4.2 %     2,476,998       4.0 %     2,574,578       4.9 %
    $ 68,010,169       100.0 %   $ 61,956,386       100.0 %   $ 52,735,730       100.0 %
 
Product revenue by significant customers as a percent of product revenues is as follows:
 
   
Percent of Product Revenue
   
Year Ended December 31,
   
2012
  
2011
  
2010
DePuy Mitek
  
61.2%
  
47.1%
  
42.7%
Bausch & Lomb Inc.
  
11.4%
  
15.8%
  
21.2%
Boehringer
  
4.2%
  
4.0%
  
4.9%
Medtronic
  
3.1%
  
5.6%
  
10.2%
Rivex Pharma
  
2.0%
  
1.3%
  
1.5%
   
81.9%
  
73.8%
  
80.5%
 
Revenues by geographic location in total and as a percentage of total revenues are as follows:
 
   
Year Ended December 31,
  
   
2012
    
2011
    
2010
  
   
Revenue
    
Percentage of Total Revenue
  
Revenue
    
Percentage of Total Revenue
  
Revenue
    
Percentage of Total Revenue
  
United States
   $ 57,904,290       81.1 %   $ 48,366,140       74.7 %   $ 38,313,594       69.0 %
Europe
     6,267,830       8.8 %     10,988,664       16.9 %     12,976,985       23.3 %
Other
     7,186,385       10.1 %     5,423,831       8.4 %     4,266,015       7.7 %
    Total
   $ 71,358,505       100.0 %   $ 64,778,635       100.0 %   $ 55,556,594       100.0 %
 
The Company recorded licensing, milestone and contract revenue of $3,348,336, $2,822,249 and $2,820,864 for the years ended December 31, 2012, 2011, and 2010, respectively. Substantially all licensing, milestone and contract revenue was derived in the United States for each year presented.
 
Net long-lived assets, consisting of net property and equipment, are subject to geographic risks because they are generally difficult to move and to effectively utilize in another geographic area in a reasonable time period and because they are relatively illiquid.
 
Net tangible long-lived assets by principal geographic areas were as follows:
 
   
Years Ended December 31,
  
   
2012
    
2011
  
United States
   $ 33,792,325     $ 34,565,770  
Italy
     1,320,656       1,904,108  
  Total
   $ 35,112,981     $ 36,469,878