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Percentage of Product Revenue by Significant Customers (Detail)	12 Months Ended
	Dec. 31, 2012	Dec. 31, 2011	Dec. 31, 2010
Revenue, Major Customer [Line Items]
Percent of Product Revenue	81.90%	73.80%	80.50%
DePuy Mitek, Inc.
Revenue, Major Customer [Line Items]
Percent of Product Revenue, greater than 10% of total revenues	61.20%	47.10%	42.70%
Bausch & Lomb Inc.
Revenue, Major Customer [Line Items]
Percent of Product Revenue, greater than 10% of total revenues	11.40%	15.80%	21.20%
Boehringer
Revenue, Major Customer [Line Items]
Percent of Product Revenue, greater than 10% of total revenues	4.20%	4.00%	4.90%
Medtronic
Revenue, Major Customer [Line Items]
Percent of Product Revenue, greater than 10% of total revenues			10.20%
Percent of Product Revenue, less than 10% of total revenues	310.00%	560.00%
Rivex Pharma
Revenue, Major Customer [Line Items]
Percent of Product Revenue, less than 10% of total revenues	2.00%	1.30%	1.50%