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Note 13 - Revenue by Product Group, by Significant Customer and by Geographic Region; Geographic Information (Details) - Product Revenue by Product Group (USD $) | 3 Months Ended | 12 Months Ended
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Dec. 31, 2013 | Sep. 30, 2013 | Jun. 30, 2013 | Mar. 31, 2013 | Dec. 31, 2012 | Sep. 30, 2012 | Jun. 30, 2012 | Mar. 31, 2012 | Dec. 31, 2013 | Dec. 31, 2012 | Dec. 31, 2011
Segment Reporting Information [Line Items] |  |  |  |  |  |  |  |  |  |  |
Product Revenue (in Dollars) | $ 20,188,488 | $ 17,023,346 | $ 20,067,407 | $ 14,494,489 | $ 21,459,124 | $ 14,055,440 | $ 18,882,277 | $ 13,613,328 | $ 71,773,730 | $ 68,010,169 | $ 61,956,386
Orthobiologics [Member] | Sales Revenue, Segment [Member] |  |  |  |  |  |  |  |  |  |  |
Segment Reporting Information [Line Items] |  |  |  |  |  |  |  |  |  |  |
Percentage of Product Revenue |  |  |  |  |  |  |  |  | 78.00% | 74.00% | 64.00%
Orthobiologics [Member] |  |  |  |  |  |  |  |  |  |  |
Segment Reporting Information [Line Items] |  |  |  |  |  |  |  |  |  |  |
Product Revenue (in Dollars) |  |  |  |  |  |  |  |  | 55,956,068 | 49,954,112 | 39,858,139
Dermal [Member] | Sales Revenue, Segment [Member] |  |  |  |  |  |  |  |  |  |  |
Segment Reporting Information [Line Items] |  |  |  |  |  |  |  |  |  |  |
Percentage of Product Revenue |  |  |  |  |  |  |  |  | 3.00% | 2.00% | 6.00%
Dermal [Member] |  |  |  |  |  |  |  |  |  |  |
Segment Reporting Information [Line Items] |  |  |  |  |  |  |  |  |  |  |
Product Revenue (in Dollars) |  |  |  |  |  |  |  |  | 1,816,602 | 1,384,403 | 3,681,166
Surgical [Member] | Sales Revenue, Segment [Member] |  |  |  |  |  |  |  |  |  |  |
Segment Reporting Information [Line Items] |  |  |  |  |  |  |  |  |  |  |
Percentage of Product Revenue |  |  |  |  |  |  |  |  | 8.00% | 7.00% | 8.00%
Surgical [Member] |  |  |  |  |  |  |  |  |  |  |
Segment Reporting Information [Line Items] |  |  |  |  |  |  |  |  |  |  |
Product Revenue (in Dollars) |  |  |  |  |  |  |  |  | 5,445,715 | 5,022,456 | 4,976,261
Ophthalmic [Member] | Sales Revenue, Segment [Member] |  |  |  |  |  |  |  |  |  |  |
Segment Reporting Information [Line Items] |  |  |  |  |  |  |  |  |  |  |
Percentage of Product Revenue |  |  |  |  |  |  |  |  | 6.00% | 13.00% | 18.00%
Ophthalmic [Member] |  |  |  |  |  |  |  |  |  |  |
Segment Reporting Information [Line Items] |  |  |  |  |  |  |  |  |  |  |
Product Revenue (in Dollars) |  |  |  |  |  |  |  |  | 4,656,560 | 8,784,011 | 10,963,822
Veterinary [Member] | Sales Revenue, Segment [Member] |  |  |  |  |  |  |  |  |  |  |
Segment Reporting Information [Line Items] |  |  |  |  |  |  |  |  |  |  |
Percentage of Product Revenue |  |  |  |  |  |  |  |  | 5.00% | 4.00% | 4.00%
Veterinary [Member] |  |  |  |  |  |  |  |  |  |  |
Segment Reporting Information [Line Items] |  |  |  |  |  |  |  |  |  |  |
Product Revenue (in Dollars) |  |  |  |  |  |  |  |  | $ 3,898,785 | $ 2,865,187 | $ 2,476,998
Sales Revenue, Segment [Member] |  |  |  |  |  |  |  |  |  |  |
Segment Reporting Information [Line Items] |  |  |  |  |  |  |  |  |  |  |
Percentage of Product Revenue |  |  |  |  |  |  |  |  | 100.00% | 100.00% | 100.00%

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