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Note 7 - Accrued Expenses (Tables) | 12 Months Ended
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Dec. 31, 2013
Payables and Accruals [Abstract] |
Schedule of Accrued Liabilities [Table Text Block] |
|  | December 31, |
|  | 2013 |  |  | 2012 |
Payroll and benefits |  | $ | 2,728,616 |  |  | $ | 2,477,833 |
Professional fees |  |  | 383,231 |  |  |  | 642,853 |
Clinical trial costs |  |  | 882,651 |  |  |  | 102,414 |
Research grants |  |  | 610,498 |  |  |  | 844,803 |
Restructuring costs |  |  | 24,638 |  |  |  | 933,732 |
Other |  |  | 908,247 |  |  |  | 835,409 |
Total |  | $ | 5,537,881 |  |  | $ | 5,837,044 |

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- Definition Tabular disclosure of the components of accrued liabilities. + References No definition available. + Details
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