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Note 7 - Accrued Expenses (Tables)

12 Months Ended

Dec. 31, 2013

Payables and Accruals [Abstract]

Schedule of Accrued Liabilities [Table Text Block]

		December 31,
		2013				2012
Payroll and benefits		$	2,728,616			$	2,477,833
Professional fees			383,231				642,853
Clinical trial costs			882,651				102,414
Research grants			610,498				844,803
Restructuring costs			24,638				933,732
Other			908,247				835,409
Total		$	5,537,881			$	5,837,044

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Tabular disclosure of the components of accrued liabilities.

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