Note 13 - Revenue by Product Group, by Significant Customer and by Geographic Region; Geographic Information (Details) - Product Revenue by Product Group (USD $)	3 Months Ended								12 Months Ended
	Dec. 31, 2013	Sep. 30, 2013	Jun. 30, 2013	Mar. 31, 2013	Dec. 31, 2012	Sep. 30, 2012	Jun. 30, 2012	Mar. 31, 2012	Dec. 31, 2013	Dec. 31, 2012	Dec. 31, 2011
Segment Reporting Information [Line Items]
Product Revenue (in Dollars)	$ 20,188,488	$ 17,023,346	$ 20,067,407	$ 14,494,489	$ 21,459,124	$ 14,055,440	$ 18,882,277	$ 13,613,328	$ 71,773,730	$ 68,010,169	$ 61,956,386
Orthobiologics [Member] \| Sales Revenue, Segment [Member]
Segment Reporting Information [Line Items]
Percentage of Product Revenue									78.00%	74.00%	64.00%
Orthobiologics [Member]
Segment Reporting Information [Line Items]
Product Revenue (in Dollars)									55,956,068	49,954,112	39,858,139
Dermal [Member] \| Sales Revenue, Segment [Member]
Segment Reporting Information [Line Items]
Percentage of Product Revenue									3.00%	2.00%	6.00%
Dermal [Member]
Segment Reporting Information [Line Items]
Product Revenue (in Dollars)									1,816,602	1,384,403	3,681,166
Surgical [Member] \| Sales Revenue, Segment [Member]
Segment Reporting Information [Line Items]
Percentage of Product Revenue									8.00%	7.00%	8.00%
Surgical [Member]
Segment Reporting Information [Line Items]
Product Revenue (in Dollars)									5,445,715	5,022,456	4,976,261
Ophthalmic [Member] \| Sales Revenue, Segment [Member]
Segment Reporting Information [Line Items]
Percentage of Product Revenue									6.00%	13.00%	18.00%
Ophthalmic [Member]
Segment Reporting Information [Line Items]
Product Revenue (in Dollars)									4,656,560	8,784,011	10,963,822
Veterinary [Member] \| Sales Revenue, Segment [Member]
Segment Reporting Information [Line Items]
Percentage of Product Revenue									5.00%	4.00%	4.00%
Veterinary [Member]
Segment Reporting Information [Line Items]
Product Revenue (in Dollars)									$ 3,898,785	$ 2,865,187	$ 2,476,998
Sales Revenue, Segment [Member]
Segment Reporting Information [Line Items]
Percentage of Product Revenue									100.00%	100.00%	100.00%