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Note 12 - Segment and Geographic Information (Tables)
3 Months Ended
Mar. 31, 2014
Segment Reporting [Abstract]  
Schedule of Segment Reporting Information, by Segment [Table Text Block]
   
Three Months Ended March 31,
 
   
2014
   
2013
 
Orthobiologics
  $ 11,572,150     $ 11,283,547  
Dermal
    188,651       241,584  
Surgical
    1,752,020       988,864  
Ophthalmic
    208,584       928,458  
Veterinary
    630,000       1,052,036  
Product revenue
  $ 14,351,405     $ 14,494,489  
Schedule of Revenue and Operating Income by Geographical Areas [Table Text Block]
   
Three Months Ended March 31,
 
   
2014
   
2013
 
   
Revenue
   
Percentage of
Revenue
   
Revenue
   
Percentage of
Revenue
 
Geographic Location:
                       
   United States
  $ 31,533,817       93 %   $ 12,280,079       80 %
   Europe
    1,695,816       5 %     1,583,993       11 %
   Other
    780,654       2 %     1,382,939       9 %
         Total revenue
  $ 34,010,287       100 %   $ 15,247,011       100 %