Note 8 - Accrued Expenses (Details) - Accrued Expenses (USD $)	Jun. 30, 2014	Dec. 31, 2013
Accrued Expenses [Abstract]
Payroll and benefits	$ 1,815,786	$ 2,728,616
Clinical trial costs	1,218,510	882,651
Professional fees	442,740	383,231
Research grants	605,132	610,498
Restructuring costs	16,208	24,638
Other	776,791	908,247
Total	$ 4,875,167	$ 5,537,881

Carrying value as of the balance sheet date of obligations incurred through that date and payable for professional fees, such as for legal and accounting services received. Used to reflect the current portion of the liabilities (due within one year or within the normal operating cycle if longer).

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Carrying value as of the balance sheet date of the obligations incurred through that date and payable for employees' services provided. Used to reflect the current portion of the liabilities (due within one year or within the normal operating cycle if longer).

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- Definition

Carrying value as of the balance sheet date of obligations incurred through that date and payable arising from transactions not otherwise specified in the taxonomy. Used to reflect the current portion of the liabilities (due within one year or within the normal operating cycle if longer).

+ References+ Details