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Note 15 - Revenue by Product Group, by Significant Customer and by Geographic Region; Geographic Information | 12 Months Ended
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Dec. 31, 2014
Segment Reporting [Abstract] |
Segment Reporting Disclosure [Text Block] | 15. Revenue by Product Group, by Significant Customer and by Geographic Region; Geographic Information Product revenue by product group is as follows:
|  | Years Ended December 31, |
|  | 2014 |  |  | 2013 |  |  | 2012 |
|  | Revenue |  |  | Percentage of Product Revenue |  |  | Revenue |  |  | Percentage of Product Revenue |  |  | Revenue |  |  | Percentage of Product Revenue |
Orthobiologics |  | $ | 61,956,870 |  |  |  | 82 | % |  | $ | 55,956,068 |  |  |  | 78 | % |  | $ | 49,954,112 |  |  |  | 74 | %
Dermal |  |  | 1,334,295 |  |  |  | 2 | % |  |  | 1,816,602 |  |  |  | 3 | % |  |  | 1,384,403 |  |  |  | 2 | %
Surgical |  |  | 5,854,876 |  |  |  | 8 | % |  |  | 5,445,715 |  |  |  | 8 | % |  |  | 5,022,456 |  |  |  | 7 | %
Ophthalmic |  |  | 3,153,435 |  |  |  | 4 | % |  |  | 4,656,560 |  |  |  | 6 | % |  |  | 8,784,011 |  |  |  | 13 | %
Veterinary |  |  | 3,174,522 |  |  |  | 4 | % |  |  | 3,898,785 |  |  |  | 5 | % |  |  | 2,865,187 |  |  |  | 4 | %
|  | $ | 75,473,998 |  |  |  | 100 | % |  | $ | 71,773,730 |  |  |  | 100 | % |  | $ | 68,010,169 |  |  |  | 100 | %
Product revenue by significant customers as a percent of product revenues is as follows:
|  | Percentage of Product Revenue Years Ended December 31, |
|  | 2014 |  |  | 2013 |  |  | 2012 |
DePuy Mitek |  |  | 72 | % |  |  | 63 | % |  |  | 61 | %
Boehringer |  |  | 4 | % |  |  | 5 | % |  |  | 4 | %
Medtronic XoMEd |  |  | 4 | % |  |  | 3 | % |  |  | 3 | %
Bausch & Lomb |  |  | 3 | % |  |  | 5 | % |  |  | 12 | %
Nordic Pharma |  |  | 2 | % |  |  | 2 | % |  |  | 1 | %
|  |  | 85 | % |  |  | 78 | % |  |  | 81 | %
Total revenue by geographic location based on the location of the customer in total and as a percentage of total revenue are as follows:
|  | Years Ended December 31, |
|  | 2014 |  |  | 2013 |  |  | 2012 |
|  | Revenue |  |  | Percentage of Total Revenue |  | Revenue |  |  | Percentage of Total Revenue |  | Revenue |  |  | Percentage of Total Revenue |
United States |  | $ | 92,259,139 |  |  |  | 87 | % |  | $ | 58,490,142 |  |  |  | 78 | % |  | $ | 57,976,667 |  |  |  | 81 | %
Europe |  |  | 6,214,441 |  |  |  | 6 | % |  |  | 7,411,568 |  |  |  | 10 | % |  |  | 6,218,890 |  |  |  | 9 | %
Other |  |  | 7,121,259 |  |  |  | 7 | % |  |  | 9,179,444 |  |  |  | 12 | % |  |  | 7,162,948 |  |  |  | 10 | %
Total |  | $ | 105,594,839 |  |  |  | 100 | % |  | $ | 75,081,154 |  |  |  | 100 | % |  | $ | 71,358,505 |  |  |  | 100 | %
The Company recorded licensing, milestone and contract revenue of $30,120,841, $3,307,424, and $3,348,336 for the years ended December 31, 2014, 2013, and 2012, respectively. Substantially all licensing, milestone, and contract revenue was derived in the United States for each year presented. Net long-lived assets, consisting of net property and equipment, are subject to geographic risks because they are generally difficult to move and to effectively utilize in another geographic area in a reasonable time period and because they are relatively illiquid. Net tangible long-lived assets by principal geographic areas were as follows:
|  | Years Ended December 31, |
|  | 2014 |  |  | 2013 |
United States |  | $ | 31,058,617 |  |  | $ | 31,999,468 |
Italy |  |  | 610,266 |  |  |  | 939,243 |
Total |  | $ | 31,668,883 |  |  | $ | 32,938,711 |

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- Definition The entire disclosure for reporting segments including data and tables. Reportable segments include those that meet any of the following quantitative thresholds a) it's reported revenue, including sales to external customers and intersegment sales or transfers is 10 percent or more of the combined revenue, internal and external, of all operating segments b) the absolute amount of its reported profit or loss is 10 percent or more of the greater, in absolute amount of 1) the combined reported profit of all operating segments that did not report a loss or 2) the combined reported loss of all operating segments that did report a loss c) its assets are 10 percent or more of the combined assets of all operating segments. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 280 -SubTopic 10 -Section 50 -Paragraph 29 -URI http://asc.fasb.org/extlink&oid=6534315&loc=d3e8864-108599 Reference 2: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 280 -SubTopic 10 -Section 50 -Paragraph 32 -URI http://asc.fasb.org/extlink&oid=6534315&loc=d3e8933-108599 Reference 3: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 280 -SubTopic 10 -Section 50 -Paragraph 26 -URI http://asc.fasb.org/extlink&oid=6534315&loc=d3e8844-108599 Reference 4: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 280 -SubTopic 10 -Section 50 -Paragraph 10 -URI http://asc.fasb.org/extlink&oid=6534315&loc=d3e8538-108599 Reference 5: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 280 -SubTopic 10 -Section 50 -Paragraph 1 -URI http://asc.fasb.org/extlink&oid=6534315&loc=d3e8380-108599 Reference 6: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 280 -SubTopic 10 -Section 50 -Paragraph 34 -URI http://asc.fasb.org/extlink&oid=6534315&loc=d3e8981-108599 Reference 7: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 280 -SubTopic 10 -Section 50 -Paragraph 35 -URI http://asc.fasb.org/extlink&oid=6534315&loc=d3e8984-108599 Reference 8: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 280 -SubTopic 10 -Section 50 -Paragraph 41 -URI http://asc.fasb.org/extlink&oid=6534315&loc=d3e9038-108599 Reference 9: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 280 -SubTopic 10 -Section 50 -Paragraph 30 -URI http://asc.fasb.org/extlink&oid=6534315&loc=d3e8906-108599 Reference 10: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 280 -SubTopic 10 -Section 50 -Paragraph 42 -URI http://asc.fasb.org/extlink&oid=6534315&loc=d3e9054-108599 Reference 11: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 280 -SubTopic 10 -Section 50 -Paragraph 31 -URI http://asc.fasb.org/extlink&oid=6534315&loc=d3e8924-108599 Reference 12: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 280 -SubTopic 10 -Section 50 -Paragraph 40 -URI http://asc.fasb.org/extlink&oid=6534315&loc=d3e9031-108599 Reference 13: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 280 -SubTopic 10 -Section 50 -Paragraph 33 -URI http://asc.fasb.org/extlink&oid=6534315&loc=d3e8971-108599 Reference 14: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 280 -SubTopic 10 -Section 50 -Paragraph 12 -URI http://asc.fasb.org/extlink&oid=6534315&loc=d3e8595-108599 + Details
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