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Note 15 - Revenue by Product Group, by Significant Customer and by Geographic Region; Geographic Information (Tables) | 12 Months Ended
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Dec. 31, 2014
Segment Reporting [Abstract] |
Schedule of Segment Reporting Information, by Segment [Table Text Block] |
|  | Years Ended December 31, |
|  | 2014 |  |  | 2013 |  |  | 2012 |
|  | Revenue |  |  | Percentage of Product Revenue |  |  | Revenue |  |  | Percentage of Product Revenue |  |  | Revenue |  |  | Percentage of Product Revenue |
Orthobiologics |  | $ | 61,956,870 |  |  |  | 82 | % |  | $ | 55,956,068 |  |  |  | 78 | % |  | $ | 49,954,112 |  |  |  | 74 | %
Dermal |  |  | 1,334,295 |  |  |  | 2 | % |  |  | 1,816,602 |  |  |  | 3 | % |  |  | 1,384,403 |  |  |  | 2 | %
Surgical |  |  | 5,854,876 |  |  |  | 8 | % |  |  | 5,445,715 |  |  |  | 8 | % |  |  | 5,022,456 |  |  |  | 7 | %
Ophthalmic |  |  | 3,153,435 |  |  |  | 4 | % |  |  | 4,656,560 |  |  |  | 6 | % |  |  | 8,784,011 |  |  |  | 13 | %
Veterinary |  |  | 3,174,522 |  |  |  | 4 | % |  |  | 3,898,785 |  |  |  | 5 | % |  |  | 2,865,187 |  |  |  | 4 | %
|  | $ | 75,473,998 |  |  |  | 100 | % |  | $ | 71,773,730 |  |  |  | 100 | % |  | $ | 68,010,169 |  |  |  | 100 | %
Schedule of Revenue by Major Customers [Table Text Block] |
|  | Percentage of Product Revenue Years Ended December 31, |
|  | 2014 |  |  | 2013 |  |  | 2012 |
DePuy Mitek |  |  | 72 | % |  |  | 63 | % |  |  | 61 | %
Boehringer |  |  | 4 | % |  |  | 5 | % |  |  | 4 | %
Medtronic XoMEd |  |  | 4 | % |  |  | 3 | % |  |  | 3 | %
Bausch & Lomb |  |  | 3 | % |  |  | 5 | % |  |  | 12 | %
Nordic Pharma |  |  | 2 | % |  |  | 2 | % |  |  | 1 | %
|  |  | 85 | % |  |  | 78 | % |  |  | 81 | %
Schedule of Revenue from External Customers Attributed to Foreign Countries by Geographic Area [Table Text Block] |
|  | Years Ended December 31, |
|  | 2014 |  |  | 2013 |  |  | 2012 |
|  | Revenue |  |  | Percentage of Total Revenue |  | Revenue |  |  | Percentage of Total Revenue |  | Revenue |  |  | Percentage of Total Revenue |
United States |  | $ | 92,259,139 |  |  |  | 87 | % |  | $ | 58,490,142 |  |  |  | 78 | % |  | $ | 57,976,667 |  |  |  | 81 | %
Europe |  |  | 6,214,441 |  |  |  | 6 | % |  |  | 7,411,568 |  |  |  | 10 | % |  |  | 6,218,890 |  |  |  | 9 | %
Other |  |  | 7,121,259 |  |  |  | 7 | % |  |  | 9,179,444 |  |  |  | 12 | % |  |  | 7,162,948 |  |  |  | 10 | %
Total |  | $ | 105,594,839 |  |  |  | 100 | % |  | $ | 75,081,154 |  |  |  | 100 | % |  | $ | 71,358,505 |  |  |  | 100 | %
Schedule of Revenue from External Customers and Long-Lived Assets, by Geographical Areas [Table Text Block] |
|  | Years Ended December 31, |
|  | 2014 |  |  | 2013 |
United States |  | $ | 31,058,617 |  |  | $ | 31,999,468 |
Italy |  |  | 610,266 |  |  |  | 939,243 |
Total |  | $ | 31,668,883 |  |  | $ | 32,938,711 |

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- Definition Tabular disclosure of the names of foreign countries from which revenue is material and the amount of revenue from external customers attributed to those countries. An entity may also provide subtotals of geographic information about groups of countries. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 225 -SubTopic 10 -Section S99 -Paragraph 2 -Subparagraph (SX 210.5-03.1) -URI http://asc.fasb.org/extlink&oid=26872669&loc=d3e20235-122688 Reference 2: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 280 -SubTopic 10 -Section 50 -Paragraph 41 -Subparagraph (a) -URI http://asc.fasb.org/extlink&oid=6534315&loc=d3e9038-108599 + Details
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- Definition Tabular disclosure of the profit or loss and total assets for each reportable segment. An entity discloses certain information on each reportable segment if the amounts (a) are included in the measure of segment profit or loss reviewed by the chief operating decision maker or (b) are otherwise regularly provided to the chief operating decision maker, even if not included in that measure of segment profit or loss. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 280 -SubTopic 10 -Section 50 -Paragraph 21 -Subparagraph (b) -URI http://asc.fasb.org/extlink&oid=6534315&loc=d3e8721-108599 Reference 2: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 280 -SubTopic 10 -Section 50 -Paragraph 25 -URI http://asc.fasb.org/extlink&oid=6534315&loc=d3e8813-108599 Reference 3: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 350 -SubTopic 20 -Section 50 -Paragraph 1 -URI http://asc.fasb.org/extlink&oid=35741047&loc=d3e13816-109267 Reference 4: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 280 -SubTopic 10 -Section 50 -Paragraph 30 -URI http://asc.fasb.org/extlink&oid=6534315&loc=d3e8906-108599 Reference 5: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 280 -SubTopic 10 -Section 50 -Paragraph 22 -URI http://asc.fasb.org/extlink&oid=6534315&loc=d3e8736-108599 + Details
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