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Note 9 - Accrued Expenses (Tables) | 12 Months Ended
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Dec. 31, 2014
Payables and Accruals [Abstract] |
Schedule of Accrued Liabilities [Table Text Block] |
|  | December 31, |
|  | 2014 |  |  | 2013 |
Compensation and related expenses |  | $ | 2,791,935 |  |  | $ | 2,870,147 |
Professional fees |  |  | 553,630 |  |  |  | 383,231 |
Clinical trial costs |  |  | 508,042 |  |  |  | 882,651 |
Research grants |  |  | 539,053 |  |  |  | 610,498 |
Restructuring costs |  |  | 8,384 |  |  |  | 24,638 |
Other |  |  | 346,482 |  |  |  | 766,716 |
Total |  | $ | 4,747,526 |  |  | $ | 5,537,881 |

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- Definition Tabular disclosure of the components of accrued liabilities. + References No definition available. + Details
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