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Condensed Consolidated Statements of Operations and Comprehensive Income (Unaudited) - USD ($)
 3 Months Ended 6 Months Ended
Jun. 30, 2015
Jun. 30, 2014
Jun. 30, 2015
Jun. 30, 2014
Product revenue $ 22,898,032 $ 21,267,156 $ 38,412,714 $ 35,618,561
Licensing, milestone and contract revenue 5,529 5,007,504 11,171 24,666,386
Total revenue 22,903,561 26,274,660 38,423,885 60,284,947
Operating expenses:        
Cost of product revenue 5,274,059 5,332,913 9,587,499 9,693,932
Research & development 1,812,320 1,873,158 3,910,082 4,160,873
Selling, general & administrative 3,388,494 3,865,876 6,993,155 7,356,861
Total operating expenses 10,474,873 11,071,947 20,490,736 21,211,666
Income from operations 12,428,688 15,202,713 17,933,149 39,073,281
Interest income, net 23,907 5,935 47,630 6,402
Income before income taxes 12,452,595 15,208,648 17,980,779 39,079,683
Provision for income taxes 4,633,038 5,906,298 6,645,665 14,747,080
Net income $ 7,819,557 $ 9,302,350 $ 11,335,114 $ 24,332,603
Basic net income per share:        
Net income (in dollars per share) $ 0.52 $ 0.63 $ 0.76 $ 1.67
Basic weighted average common shares outstanding (in shares) 14,961,436 14,687,747 14,933,534 14,559,917
Diluted net income per share:        
Net income (in dollars per share) $ 0.51 $ 0.60 $ 0.74 $ 1.57
Diluted weighted average common shares outstanding (in shares) 15,335,687 15,492,732 15,332,391 15,487,432
Net income $ 7,819,557 $ 9,302,350 $ 11,335,114 $ 24,332,603
Other comprehensive income (loss):        
Unrealized loss on securities, net of tax (3,198)   (3,198)  
Foreign currency translation adjustment 420,684 $ (190,739) (1,828,444) $ (216,855)
Total other comprehensive income (loss) 417,486 (190,739) (1,831,642) (216,855)
Comprehensive income $ 8,237,043 $ 9,111,611 $ 9,503,472 $ 24,115,748