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Note 16 - Revenue by Product Group, by Significant Customer and by Geographic Region; Geographic Information
 12 Months Ended
Dec. 31, 2015
Notes to Financial Statements  
Segment Reporting Disclosure [Text Block]
16. Revenue by Product Group, by Significant Customer and by Geographic Region; Geographic Information
 
Product revenue by product group is as follows (in thousands, except percentages):
 
    Years Ended December 31,
    2015   2014   2013
    Revenue   Percentage of Product Revenue   Revenue   Percentage of Product Revenue   Revenue   Percentage of Product Revenue
Orthobiologics   $ 73,247       84 %   $ 61,957       82 %   $ 55,956       78 %
Dermal     2,266       2 %     1,334       2 %     1,817       3 %
Surgical     5,812       7 %     5,855       8 %     5,446       8 %
Other     6,371       7 %     6,328       8 %     8,555       11 %
    $ 87,696       100 %   $ 75,474       100 %   $ 71,774       100 %
 
Product revenue by significant customers as a percent of product revenues is as follows:
 
    Percentage of Product Revenue
Years Ended December 31,
    2015   2014   2013
Mitek     72 %     72 %     63 %
Boehringer     5 %     4 %     5 %
Medtronic     3 %     4 %     3 %
Nordic Pharma     2 %     2 %     2 %
Pharmascience     2 %     2 %     3 %
      84 %     84 %     76 %
 
Total revenue by geographic location based on the location of the customer in total and as a percentage of total revenue are as follows (in thousands, except percentages):
 
 
    Years Ended December 31,
    2015   2014   2013
    Total
Revenue		   Percentage of
Revenue		   Total
Revenue		   Percentage of
Revenue		   Total
Revenue		   Percentage of
Revenue
Geographic Location:                                                
United States   $ 76,621       82 %   $ 92,259       87 %   $ 58,490       78 %
Europe     8,756       9 %     6,215       6 %     7,412       10 %
Other     7,622       9 %     7,121       7 %     9,179       12 %
Total   $ 92,999       100 %   $ 105,595       100 %   $ 75,081       100 %
 
The Company recorded licensing, milestone, and contract revenue of $5.3 million, $30.1 million and $3.3 million for the years ended December 31, 2015, 2014, and 2013, respectively. Substantially all licensing, milestone, and contract revenue was derived in the United States for each year presented.
 
Net long-lived assets, consisting of net property and equipment, are subject to geographic risks because they are generally difficult to move and to effectively utilize in another geographic area in a reasonable time period and because they are relatively illiquid. Net tangible long-lived assets by principal geographic areas were as follows (in thousands):
 
    Years Ended December 31,
    2015   2014
United States   $ 39,732     $ 31,059  
Italy     376       610  
Total   $ 40,108     $ 31,669