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Condensed Consolidated Statements of Operations and Comprehensive Income - USD ($)
shares in Thousands, $ in Thousands
 12 Months Ended
Dec. 31, 2015
Dec. 31, 2014
Dec. 31, 2013
Product revenue $ 87,696 $ 75,474 $ 71,774
Licensing, milestone and contract revenue 5,303 30,121 3,307
Total revenue 92,999 105,595 75,081
Operating expenses:      
Cost of product revenue 21,053 20,930 22,765
Research & development 8,987 8,144 7,060
Selling, general & administrative $ 14,825 $ 15,074 12,936
Restructuring credits (287)
Total operating expenses $ 44,865 $ 44,148 42,474
Income from operations 48,134 61,447 32,607
Interest income (expense), net 120 58 (127)
Income before income taxes 48,254 61,505 32,480
Provision for income taxes 17,496 23,186 11,905
Net income $ 30,758 $ 38,319 $ 20,575
Basic net income per share:      
Basic net income per share (in dollars per share) $ 2.06 $ 2.61 $ 1.46
Basic weighted average common shares outstanding (in shares) 14,934 14,678 14,087
Diluted net income per share:      
Diluted net income per share (in dollars per share) $ 2.01 $ 2.51 $ 1.39
Diluted weighted average common shares outstanding (in shares) 15,321 15,269 14,826
Net income $ 30,758 $ 38,319 $ 20,575
Other comprehensive income (loss):      
Foreign currency translation adjustment (2,154) (2,796) 956
Comprehensive income $ 28,604 $ 35,523 $ 21,531