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Consolidated Statements of Operations and Comprehensive Income - USD ($)
shares in Thousands, $ in Thousands
 12 Months Ended
Dec. 31, 2016
Dec. 31, 2015
Dec. 31, 2014
Product Revenue $ 102,932 $ 87,696 $ 75,474
Licensing, milestone and contract revenue 447 5,303 30,121
Total revenue 103,379 92,999 105,595
Operating expenses:      
Cost of product revenue 24,027 21,053 20,930
Research & development 10,732 8,987 8,144
Selling, general & administrative 18,013 14,825 15,074
Total operating expenses 52,772 44,865 44,148
Income from operations 50,607 48,134 61,447
Interest income, net 263 120 58
Income before income taxes 50,870 48,254 61,505
Provision for income taxes 18,323 17,496 23,186
Net income $ 32,547 $ 30,758 $ 38,319
Basic net income per share:      
Net income (in dollars per share) $ 2.22 $ 2.06 $ 2.61
Basic weighted average common shares outstanding (in shares) 14,682 14,934 14,678
Diluted net income per share:      
Net income (in dollars per share) $ 2.15 $ 2.01 $ 2.51
Diluted weighted average common shares outstanding (in shares) 15,116 15,321 15,269
Net income $ 32,547 $ 30,758 $ 38,319
Other comprehensive loss:      
Foreign currency translation adjustment (668) (2,154) (2,796)
Comprehensive income $ 31,879 $ 28,604 $ 35,523