<SEC-DOCUMENT>0001157523-17-002787.txt : 20171025
<SEC-HEADER>0001157523-17-002787.hdr.sgml : 20171025
<ACCEPTANCE-DATETIME>20171025160622
ACCESSION NUMBER:		0001157523-17-002787
CONFORMED SUBMISSION TYPE:	8-K
PUBLIC DOCUMENT COUNT:		2
CONFORMED PERIOD OF REPORT:	20171025
ITEM INFORMATION:		Results of Operations and Financial Condition
ITEM INFORMATION:		Financial Statements and Exhibits
FILED AS OF DATE:		20171025
DATE AS OF CHANGE:		20171025

FILER:

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			Anika Therapeutics, Inc.
		CENTRAL INDEX KEY:			0000898437
		STANDARD INDUSTRIAL CLASSIFICATION:	SURGICAL & MEDICAL INSTRUMENTS & APPARATUS [3841]
		IRS NUMBER:				043145961
		STATE OF INCORPORATION:			MA
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		8-K
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	001-14027
		FILM NUMBER:		171153153

	BUSINESS ADDRESS:	
		STREET 1:		32 WIGGINS AVENUE
		CITY:			BEDFORD
		STATE:			MA
		ZIP:			01730
		BUSINESS PHONE:		(781) 457-9000

	MAIL ADDRESS:	
		STREET 1:		32 WIGGINS AVENUE
		CITY:			BEDFORD
		STATE:			MA
		ZIP:			01730

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	ANIKA THERAPEUTICS INC
		DATE OF NAME CHANGE:	19970114

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	ANIKA RESEARCH INC
		DATE OF NAME CHANGE:	19930309
</SEC-HEADER>
<DOCUMENT>
<TYPE>8-K
<SEQUENCE>1
<FILENAME>a51705116.htm
<DESCRIPTION>ANIKA THERAPEUTICS, INC. 8-K
<TEXT>
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      <font style="font-size: 16pt; font-family: Times New Roman">UNITED STATES</font><font style="font-size: 16pt; font-family: Times New Roman"><br style="font-family: Times New Roman; font-size: 16pt"></font><font style="font-size: 16pt; font-family: Times New Roman">SECURITIES
      AND EXCHANGE COMMISSION</font><br><br><font style="font-size: 11pt">Washington,
      D.C. 20549</font><font style="font-size: 11pt"><br style="font-size: 11pt"></font><font style="font-size: 11pt"><br style="font-size: 11pt"></font><font style="font-size: 16pt; font-family: Times New Roman">FORM
      8-K</font><font style="font-size: 11pt"><br style="font-size: 11pt"></font><font style="font-size: 11pt"><br style="font-size: 11pt"></font><font style="font-size: 11pt">CURRENT
      REPORT</font><font style="font-size: 11pt"><br style="font-size: 11pt"></font><font style="font-size: 11pt">PURSUANT
      TO SECTION 13 OR 15(d)</font><br><font style="font-size: 11pt">OF THE
      SECURITIES EXCHANGE ACT OF 1934</font><font style="font-size: 11pt"><br style="font-size: 11pt"></font><font style="font-size: 11pt"><br style="font-size: 11pt"></font><font style="font-size: 11pt; font-family: Times New Roman">Date
      of Report (Date of earliest event reported): October 25, 2017</font><font style="font-size: 11pt"><br style="font-size: 11pt"></font><font style="font-size: 11pt"><br style="font-size: 11pt"></font><font style="font-size: 16pt">Anika
      Therapeutics, Inc.</font><font style="font-size: 11pt"><br style="font-size: 11pt"></font><font style="font-size: 11pt">(</font><i><font style="font-size: 11pt">Exact
      name of registrant as specified in its charter</font></i><font style="font-size: 11pt">)</font>
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            Massachusetts
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            000-21326
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          <p style="margin-bottom: 0px; margin-top: 0px">
            04-3145961
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            <i>(State or other jurisdiction of</i><br><i>incorporation or
            organization)</i>
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            <i>Commission file number</i>
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            <i>(I.R.S. Employer<br>Identification No.)</i>
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          <p style="margin-bottom: 0px; margin-top: 0px">
            32 Wiggins Avenue, Bedford, MA 01730
          </p>
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          <p style="margin-bottom: 0px; margin-top: 0px">
            <i>(Address of principal executive offices) (Zip code)</i>
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    <p style="text-align: center; white-space: nowrap">
      <br>
      (<font style="font-size: 10pt; font-family: Times New Roman">781)-457-9000</font><br><i><font style="font-size: 10pt; font-family: Times New Roman">Registrant&#8217;s
      telephone number, including area code:&#160;&#160;&#160;</font></i><br><br><br>
    </p>
    <p style="text-align: center">
      Not Applicable<br><i><font style="font-size: 10pt; font-family: Times New Roman">(Former
      name or former address, if changed since last report)</font></i><br>
    </p>
    <hr style="width: 15%; text-align: center; color: #000000; height: 1.0 pt">


    <p>

    </p>
    <p>
      <font style="font-size: 10pt; font-family: Times New Roman">Check the
      appropriate box below if the Form 8-K filing is intended to
      simultaneously satisfy the filing obligation of the registrant under any
      of the following provisions:</font><br><font style="font-size: 10pt; font-family: Arial Unicode MS">&#8414;</font>
      <font style="font-size: 10pt; font-family: Times New Roman">Written
      communications pursuant to Rule 425 under the Securities Act (17 CFR
      230.425)</font><br><font style="font-size: 10pt; font-family: Arial Unicode MS">&#8414;</font>
      <font style="font-size: 10pt; font-family: Times New Roman">Soliciting
      material pursuant to Rule 14a-12 under the Exchange Act (17 CFR
      240.14a-12)</font><br><font style="font-size: 10pt; font-family: Arial Unicode MS">&#8414;</font>
      <font style="font-size: 10pt; font-family: Times New Roman">Pre-commencement
      communications pursuant to Rule 14d-2(b) under the Exchange Act (17 CFR
      240.14d-2(b))</font><br><font style="font-size: 10pt; font-family: Arial Unicode MS">&#8414;</font>
      <font style="font-size: 10pt; font-family: Times New Roman">Pre-commencement
      communications pursuant to Rule 13e-4(c) under the Exchange Act (17 CFR
      240.13e-4(c))</font><br><br>Indicate by check mark whether the
      registrant is an emerging growth company as defined in Rule 405 of the
      Securities Act of 1933 (17 CFR &#167;230.405) or Rule 12b-2 of the Securities
      Exchange Act of 1934 (17 CFR &#167;240.12b-2).<br>Emerging growth
      company&#160;&#160;&#160;<font style="font-size: 10pt; font-family: Arial Unicode MS">&#8414;</font>
    </p>
    <p>
      If an emerging growth company, indicate by check mark if the registrant
      has elected not to use the extended transition period for complying with
      any new or revised financial accounting standards provided pursuant to
      Section 13(a) of the Exchange Act.&#160;&#160;&#160;<font style="font-size: 10pt; font-family: Arial Unicode MS">&#8414;</font>
    </p>
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    <p style="white-space: nowrap">
      <b>Item 2.02.&#160;&#160;Results of Operations and Financial Condition</b>.
    </p>
    <p>
      The following information, including the exhibit attached hereto, is
      intended to be furnished and shall not be deemed &quot;filed&quot; for purposes of
      Section 18 of the Securities Exchange Act of 1934 (the &quot;Exchange Act&quot;)
      or otherwise subject to the liabilities of that section, nor shall it be
      deemed incorporated by reference in any filing under the Securities Act
      of 1933 or the Exchange Act, except as expressly set forth by specific
      reference in such filing.
    </p>
    <p>
      On October 25, 2017, Anika Therapeutics, Inc. issued a press release
      announcing its financial results for the third quarter ended September
      30, 2017. The full text of the press release is furnished as Exhibit
      99.1 hereto and is incorporated herein by reference.
    </p>
    <p style="white-space: nowrap">
      <b>Item 9.01.&#160;&#160;Financial Statements and Exhibits</b>.
    </p>
    <p style="white-space: nowrap">
      (d)&#160;&#160;Exhibits.
    </p>
    <p style="white-space: nowrap">
      99.1&#160;&#160;Press Release of Anika Therapeutics, Inc. dated October 25, 2017.
    </p>
    <p style="text-align: center; white-space: nowrap">
      <br>
      <br>
      <br>
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    <p style="text-align: center">
      <font style="font-size: 10pt; font-family: Times New Roman">SIGNATURE</font><br>
    </p>
    <p>
      Pursuant to the requirements of the Securities Exchange Act of 1934, the
      registrant has duly caused this report to be filed on its behalf by the
      undersigned hereunto duly authorized.
    </p>
    <p>

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            Anika Therapeutics, Inc.
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            &#160;
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            Dated: October 25, 2017
          </p>
        </td>
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          By:
        </td>
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            /s/ Sylvia Cheung
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            &#160;
          </p>
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          <p style="margin-bottom: 0px; margin-top: 0px">
            Sylvia Cheung
          </p>
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            &#160;
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          <p style="margin-bottom: 0px; margin-top: 0px">
            Chief Financial Officer
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    <p>

    </p>
    <p style="text-align: center">
      Exhibit Index<br><br>
    </p>
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            <a href="a51705116ex99_1.htm">99.1</a>
          </p>
        </td>
        <td valign="top" style="width: 88%; text-align: left; padding-left: 0.0px">
          <p style="margin-bottom: 0px; margin-top: 0px">
            <a href="a51705116ex99_1.htm">Press Release of Anika Therapeutics,
            Inc. dated October 25, 2017.</a>
          </p>
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<TYPE>EX-99.1
<SEQUENCE>2
<FILENAME>a51705116ex99_1.htm
<DESCRIPTION>EXHIBIT 99.1
<TEXT>
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    <p style="text-align: right">
      <b>Exhibit 99.1</b>
    </p>
    <p style="text-align: center">
      <font style="font-size: 12pt; font-family: Times New Roman"><b>Anika
      Reports Third Quarter 2017 Financial Results</b></font>
    </p>
    <p style="text-align: center">
      <i><font style="font-size: 12pt; font-family: Times New Roman"><b>Completed
      Enrollment in CINGAL Phase III Clinical Trial;</b></font></i><b><font style="font-size: 12pt; font-family: Times New Roman"><br style="font-size: 12pt; font-family: Times New Roman"></font><i><font style="font-size: 12pt; font-family: Times New Roman">Advancement
      of Regenerative Medicine Pipeline;</font></i><font style="font-size: 12pt; font-family: Times New Roman"><br style="font-size: 12pt; font-family: Times New Roman"></font><i><font style="font-size: 12pt; font-family: Times New Roman">MONOVISC
      Revenue Increased 50% Year-over-Year</font></i></b>
    </p>
    <p style="text-align: center">

    </p>
    <p>
      BEDFORD, Mass.--(BUSINESS WIRE)--October 25, 2017--Anika Therapeutics,
      Inc. (NASDAQ: ANIK), a global, integrated orthopedic medicines company
      specializing in therapeutics based on its proprietary hyaluronic acid
      (&#8220;HA&#8221;) technology, today reported financial results for the third
      quarter ended September 30, 2017, along with business progress in the
      period.
    </p>
    <p>
      &#8220;Anika made significant progress on multiple fronts executing its
      long-term growth strategy, highlighted by the early completion of
      enrollment in the CINGAL&#174; Phase III trial, regulatory clearances for the
      expansion of MONOVISC&#174; into India, Australia, and Taiwan, pipeline
      advancements and the bolstering of our executive and commercial
      leadership team,&#8221; said Charles H. Sherwood, Ph.D., Chief Executive
      Officer. &#8220;MONOVISC continued to gain worldwide market share in the third
      quarter as physicians continue to migrate towards single-injection
      solutions, resulting in MONOVISC revenue growth of 50% year-over-year
      for the quarter. Additionally, we advanced our regenerative medicine
      pipeline with the submission of a 510(k) application to the U.S. Food
      and Drug Administration for our injectable HA-based bone repair
      treatment, a promising new opportunity gaining attention in the
      orthopedic space.&#8221;
    </p>
    <p>
      <b>Third Quarter Financial Results</b>
    </p>
    <ul>
      <li style="margin-bottom: 10.0px">
        Total revenue for the third quarter of 2017 increased 5%
        year-over-year to $27.2 million, compared to $25.8 million for the
        third quarter of 2016.
      </li>
      <li style="margin-bottom: 10.0px">
        Worldwide Orthobiologics revenue grew 7% year-over-year in the third
        quarter of 2017. The main driver of this product revenue growth was an
        increase in global MONOVISC revenue of 50% year-over-year in the third
        quarter of 2017, which was partially offset by the continued decline
        in ORTHOVISC&#174; revenue in the same period, mirroring the industry shift
        from multiple- to single-injection therapies.
      </li>
      <li style="margin-bottom: 10.0px">
        International Orthobiologics revenue increased 10% year-over-year for
        the third quarter of 2017, due primarily to the global expansion of
        MONOVISC, as well as the growth of CINGAL. Domestically, ORTHOVISC and
        MONOVISC continue to maintain a combined market-leading position.
      </li>
      <li style="margin-bottom: 10.0px">
        Total operating expenses for the third quarter of 2017 were $16.9
        million, compared to $12.1 million for the third quarter of 2016. The
        increase in total operating expenses was due primarily to higher
        research and development investments required to advance the Company&#8217;s
        growing pipeline towards regulatory approvals, and the expansion of
        the commercial team in anticipation of those product launches.
      </li>
      <li style="margin-bottom: 10.0px">
        Net income for the third quarter of 2017 was $6.9 million, or $0.46
        per diluted share, compared to $9.0 million, or $0.59 per diluted
        share, for the third quarter of 2016. The decline in net income was
        due primarily to the planned increase in operating expenses previously
        discussed.
      </li>
    </ul>
    <div style="margin-left: 0pt; width: 100%; margin-bottom: 10pt; text-indent: 0pt; margin-right: 0pt">
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        <div style="text-align: left">

        </div>
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    </div>
    <p>
      <b>Recent Business Highlights</b><br>The Company made key commercial,
      operational, pipeline, and financial advancements, including:
    </p>
    <ul>
      <li style="margin-bottom: 10.0px">
        Completing enrollment well ahead of schedule in the second pivotal
        Phase III trial evaluating CINGAL, the Company&#8217;s novel
        HA-corticosteroid combination viscosupplement for the treatment of
        symptoms associated with osteoarthritis (OA) of the knee. The Phase
        III trial, which will evaluate 576 patients with mild to moderate knee
        osteoarthritis, is designed to evaluate the safety of CINGAL as well
        as its effectiveness in improving pain, function, and quality of life
        measures over a 26-week period, in comparison to MONOVISC and
        triamcinolone hexacetonide. Enrollment was completed well ahead of
        internal estimates largely due to physician and patient interest, and
        enthusiasm surrounding the immediate and durable joint relief possible
        with CINGAL.
      </li>
      <li style="margin-bottom: 10.0px">
        Receiving regulatory approval for MONOVISC in India, Australia and
        Taiwan for the treatment of pain associated with osteoarthritis of all
        synovial joints. Sales in those countries are expected to begin in the
        fourth quarter of 2017.
      </li>
      <li style="margin-bottom: 10.0px">
        Advancing Anika&#8217;s regenerative medicine pipeline with the submission
        of a 510(k) application to the U.S. Food and Drug Administration for
        its injectable HA-based bone repair treatment. This treatment provides
        an injectable, self-setting, osteoconductive bone graft substitute
        that resorbs and is replaced by the growth of new bone during the
        healing process.
      </li>
      <li style="margin-bottom: 10.0px">
        Publishing data demonstrating the efficacy and safety of HYALOFAST&#174; in
        combination with autologous adult mesenchymal stem cells for the
        treatment of cartilage lesions on the knee in the peer-reviewed
        journal Knee Surgery Sports Traumatology Arthroscopy.
      </li>
      <li style="margin-bottom: 10.0px">
        Strengthening the Company&#8217;s executive leadership team with the
        appointments of Joseph Darling as President, Steven Chartier as Vice
        President of Regulatory and Clinical Affairs, and the anticipated
        appointment of Thomas Finnerty as Chief Human Resources Officer on
        October 30.
      </li>
      <li style="margin-bottom: 10.0px">
        Continued progress towards full consolidation of the Company&#8217;s global
        manufacturing operations at Anika&#8217;s Bedford, Massachusetts corporate
        headquarters.
      </li>
    </ul>
    <p>
      <b>Conference Call Information</b><br>Anika&#8217;s management will hold a
      conference call and webcast to discuss its financial results and
      business highlights tomorrow, Thursday, October 26<sup>th</sup> at 9:00
      am ET. The conference call can be accessed by dialing 1-855-468-0611
      (toll-free domestic) or 1-484-756-4332 (international). A live audio
      webcast will be available in the &quot;Investor Relations&quot; section of Anika&#8217;s
      website, <u>www.anikatherapeutics.com</u>. An accompanying slide
      presentation may also be accessed via the Anika website. A replay of the
      webcast will be available on Anika&#8217;s website approximately two hours
      after the completion of the event.
    </p>
    <div style="margin-left: 0pt; width: 100%; margin-bottom: 10pt; text-indent: 0pt; margin-right: 0pt">
      <div>
        <div style="text-align: left">

        </div>
      </div>
      <div style="page-break-after: always">
        <div style="text-align: center">

        </div>
        <div style="text-align: center">
          <hr style="color: black; height: 1.5pt">

        </div>
      </div>
      <div>
        <div style="text-align: right">

        </div>
      </div>
    </div>
    <p>
      <b>About Anika Therapeutics, Inc.</b><br>Anika Therapeutics,
      Inc.&#160;(NASDAQ: ANIK) is a global, integrated orthopedic medicines company
      based in&#160;Bedford, Massachusetts.&#160;Anika is committed to improving the
      lives of patients with degenerative orthopedic diseases and traumatic
      conditions with clinically meaningful therapies along the continuum of
      care, from palliative pain management to regenerative cartilage repair.
      The Company has over two decades of global expertise developing,
      manufacturing, and commercializing more than 20 products based on its
      proprietary&#160;hyaluronic acid (HA) technology. Anika's orthopedic medicine
      portfolio includes ORTHOVISC, MONOVISC, and CINGAL, which alleviate pain
      and restore joint function by replenishing depleted HA, and HYALOFAST, a
      solid HA-based scaffold to aid cartilage repair and regeneration. For
      more information about Anika, please visit&#160;<u>www.anikatherapeutics.com</u>.
    </p>
    <p>
      <b>Forward-Looking Statements</b><br><i>The statements made in the last
      sentence of the second bullet point and in the fifth bullet point in the
      section captioned &#8220;Recent Business Highlights&#8221; of this press release,
      which are not statements of historical fact, are forward-looking
      statements within the meaning of Section 27A of the Securities Act of
      1933, as amended, and Section 21E of the Securities Exchange Act of
      1934, as amended. These statements include, but are not limited to,
      those relating to sales expectations with regard to the Company&#8217;s
      MONOVISC product and to the Company&#8217;s appointment of personnel. These
      statements are based upon the current beliefs and expectations of the
      Company&#8217;s management and are subject to significant risks,
      uncertainties, and other factors. The Company&#8217;s actual results could
      differ materially from any anticipated future results, performance, or
      achievements described in the forward-looking statements as a result of
      a number of factors including, but not limited to, (i) the Company&#8217;s
      ability to successfully commence and/or complete clinical trials of its
      products on a timely basis or at all; (ii) the Company&#8217;s ability to
      obtain pre-clinical or clinical data to support domestic and
      international pre-market approval applications, 510(k) applications, or
      new drug applications, or to timely file and receive FDA or other
      regulatory approvals or clearances of its products; (iii) that such
      approvals will not be obtained in a timely manner or without the need
      for additional clinical trials, other testing or regulatory submissions,
      as applicable; (iv) the Company&#8217;s research and product development
      efforts and their relative success, including whether we have any
      meaningful sales of any new products resulting from such efforts; (v)
      the cost effectiveness and efficiency of the Company&#8217;s clinical studies,
      manufacturing operations, and production planning; (vi) the strength of
      the economies in which the Company operates or will be operating, as
      well as the political stability of any of those geographic areas; (vii)
      future determinations by the Company to allocate resources to products
      and in directions not presently contemplated; (viii) the Company&#8217;s
      ability to successfully commercialize its products, in the U.S. and
      abroad; (ix) the Company&#8217;s ability to provide an adequate and timely
      supply of its products to its customers; and (x) the Company&#8217;s ability
      to achieve its growth targets. Additional factors and risks are
      described in the Company&#8217;s periodic reports filed with the Securities
      and Exchange Commission, and they are available on the SEC&#8217;s website at <u>www.sec.gov</u>.
      Forward-looking statements are made based on information available to
      the Company on the date of this press release, and the Company assumes
      no obligation to update the information contained in this press release.</i>
    </p>
    <div style="margin-left: 0pt; width: 100%; margin-bottom: 10pt; text-indent: 0pt; margin-right: 0pt">
      <div>
        <div style="text-align: left">

        </div>
      </div>
      <div style="page-break-after: always">
        <div style="text-align: center">

        </div>
        <div style="text-align: center">
          <hr style="color: black; height: 1.5pt">

        </div>
      </div>
      <div>
        <div style="text-align: right">

        </div>
      </div>
    </div>
<div style="text-align:left">
    <table cellspacing="0" style="width: 100%; font-family: Times New Roman; margin-bottom: 10.0px; font-size: 8pt">
      <tr>
        <td>

        </td>
        <td>
          &#160;
        </td>
        <td>
          &#160;
        </td>
        <td colspan="3">

        </td>
        <td>
          &#160;
        </td>
        <td>
          &#160;
        </td>
        <td colspan="3">

        </td>
        <td>
          &#160;
        </td>
        <td>
          &#160;
        </td>
        <td>
          &#160;
        </td>
        <td colspan="2">

        </td>
        <td>
          &#160;
        </td>
        <td>
          &#160;
        </td>
        <td colspan="2">

        </td>
      </tr>
      <tr>
        <td colspan="20" valign="top" style="text-align: center; padding-left: 0.0px">
          <b>Anika Therapeutics, Inc. and Subsidiaries</b>
        </td>
      </tr>
      <tr>
        <td colspan="20" valign="top" style="text-align: center; padding-left: 0.0px">
          <b>Condensed Consolidated Statements of Operations</b>
        </td>
      </tr>
      <tr>
        <td colspan="20" valign="top" style="text-align: center; padding-left: 0.0px">
          <b>(in thousands, except per share data)</b>
        </td>
      </tr>
      <tr>
        <td colspan="20" valign="top" style="text-align: center; padding-left: 0.0px">
          (unaudited)
        </td>
      </tr>
      <tr>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td colspan="3">

        </td>
        <td>

        </td>
        <td>

        </td>
        <td colspan="3">

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td colspan="2">

        </td>
        <td>

        </td>
        <td>

        </td>
        <td colspan="2">
          &#160;
        </td>
      </tr>
      <tr>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td colspan="8" valign="top" style="text-align: center; padding-left: 0.0px">
          <b>For the Three Months Ended September 30,</b>
        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td colspan="6" valign="top" style="text-align: center; padding-left: 0.0px">
          <b>For the Nine Months Ended September 30,</b>
        </td>
      </tr>
      <tr>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td colspan="3" valign="bottom" style="padding-right: 0.0px; border-bottom-width: 1.0pt; text-align: center; padding-left: 0.0px; border-bottom-style: solid; border-bottom-color: black; white-space: nowrap">
          <b>2017</b>
        </td>
        <td>

        </td>
        <td>

        </td>
        <td colspan="3" valign="bottom" style="padding-right: 0.0px; border-bottom-width: 1.0pt; text-align: center; padding-left: 0.0px; border-bottom-style: solid; border-bottom-color: black; white-space: nowrap">
          <b>2016</b>
        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td colspan="2" valign="bottom" style="padding-right: 0.0px; border-bottom-width: 1.0pt; text-align: center; padding-left: 0.0px; border-bottom-style: solid; border-bottom-color: black; white-space: nowrap">
          <b>2017</b>
        </td>
        <td>

        </td>
        <td>

        </td>
        <td colspan="2" valign="bottom" style="padding-right: 0.0px; border-bottom-width: 1.0pt; text-align: center; padding-left: 0.0px; border-bottom-style: solid; border-bottom-color: black; white-space: nowrap">
          <b>2016</b>
        </td>
      </tr>
      <tr>
        <td valign="top" style="text-align: left; padding-left: 0.0px">
          Product revenue
        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-right: 0.0px; text-align: right; padding-left: 0.0px; white-space: nowrap">
          $
        </td>
        <td valign="bottom" style="padding-right: 0.0px; text-align: right; padding-left: 0.0px; white-space: nowrap">
          27,178
        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-right: 0.0px; text-align: right; padding-left: 0.0px; white-space: nowrap">
          $
        </td>
        <td valign="bottom" style="padding-right: 0.0px; text-align: right; padding-left: 0.0px; white-space: nowrap">
          25,783
        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-right: 0.0px; text-align: right; padding-left: 0.0px; white-space: nowrap">
          $
        </td>
        <td valign="bottom" style="padding-right: 0.0px; text-align: right; padding-left: 0.0px; white-space: nowrap">
          78,899
        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-right: 0.0px; text-align: right; padding-left: 0.0px; white-space: nowrap">
          $
        </td>
        <td valign="bottom" style="padding-right: 0.0px; text-align: right; padding-left: 0.0px; white-space: nowrap">
          74,636
        </td>
      </tr>
      <tr>
        <td valign="top" style="text-align: left; padding-left: 0.0px; padding-bottom: 2.0px">
          Licensing, milestone and contract revenue
        </td>
        <td>

        </td>
        <td>

        </td>
        <td style="border-bottom-width: 1.0pt; border-bottom-style: solid; border-bottom-color: black">
          &#160;
        </td>
        <td valign="bottom" style="padding-right: 0.0px; border-bottom-width: 1.0pt; text-align: right; padding-left: 0.0px; border-bottom-style: solid; border-bottom-color: black; white-space: nowrap">
          6
        </td>
        <td style="border-bottom-width: 1.0pt; border-bottom-style: solid; border-bottom-color: black">
          &#160;
        </td>
        <td>

        </td>
        <td>

        </td>
        <td style="border-bottom-width: 1.0pt; border-bottom-style: solid; border-bottom-color: black">
          &#160;
        </td>
        <td valign="bottom" style="padding-right: 0.0px; border-bottom-width: 1.0pt; text-align: right; padding-left: 0.0px; border-bottom-style: solid; border-bottom-color: black; white-space: nowrap">
          6
        </td>
        <td style="border-bottom-width: 1.0pt; border-bottom-style: solid; border-bottom-color: black">
          &#160;
        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td style="border-bottom-width: 1.0pt; border-bottom-style: solid; border-bottom-color: black">
          &#160;
        </td>
        <td valign="bottom" style="padding-right: 0.0px; border-bottom-width: 1.0pt; text-align: right; padding-left: 0.0px; border-bottom-style: solid; border-bottom-color: black; white-space: nowrap">
          5,133
        </td>
        <td>

        </td>
        <td>

        </td>
        <td style="border-bottom-width: 1.0pt; border-bottom-style: solid; border-bottom-color: black">
          &#160;
        </td>
        <td valign="bottom" style="padding-right: 0.0px; border-bottom-width: 1.0pt; text-align: right; padding-left: 0.0px; border-bottom-style: solid; border-bottom-color: black; white-space: nowrap">
          17
        </td>
      </tr>
      <tr>
        <td valign="top" style="text-align: left; padding-left: 20.0px">
          Total revenue
        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-right: 0.0px; text-align: right; padding-left: 0.0px; white-space: nowrap">
          27,184
        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-right: 0.0px; text-align: right; padding-left: 0.0px; white-space: nowrap">
          25,789
        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-right: 0.0px; text-align: right; padding-left: 0.0px; white-space: nowrap">
          84,032
        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-right: 0.0px; text-align: right; padding-left: 0.0px; white-space: nowrap">
          74,653
        </td>
      </tr>
      <tr>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td colspan="3">

        </td>
        <td>

        </td>
        <td>

        </td>
        <td colspan="3">

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td colspan="2">

        </td>
        <td>

        </td>
        <td>

        </td>
        <td colspan="2">
          &#160;
        </td>
      </tr>
      <tr>
        <td valign="top" style="text-align: left; padding-left: 0.0px">
          Operating expenses:
        </td>
        <td>

        </td>
        <td>

        </td>
        <td colspan="3">

        </td>
        <td>

        </td>
        <td>

        </td>
        <td colspan="3">

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td colspan="2">

        </td>
        <td>

        </td>
        <td>

        </td>
        <td colspan="2">

        </td>
      </tr>
      <tr>
        <td valign="top" style="text-align: left; padding-left: 20.0px">
          Cost of product revenue
        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-right: 0.0px; text-align: right; padding-left: 0.0px; white-space: nowrap">
          6,250
        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-right: 0.0px; text-align: right; padding-left: 0.0px; white-space: nowrap">
          4,998
        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-right: 0.0px; text-align: right; padding-left: 0.0px; white-space: nowrap">
          18,648
        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-right: 0.0px; text-align: right; padding-left: 0.0px; white-space: nowrap">
          16,488
        </td>
      </tr>
      <tr>
        <td valign="top" style="text-align: left; padding-left: 20.0px">
          Research and development
        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-right: 0.0px; text-align: right; padding-left: 0.0px; white-space: nowrap">
          5,842
        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-right: 0.0px; text-align: right; padding-left: 0.0px; white-space: nowrap">
          2,822
        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-right: 0.0px; text-align: right; padding-left: 0.0px; white-space: nowrap">
          14,521
        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-right: 0.0px; text-align: right; padding-left: 0.0px; white-space: nowrap">
          7,773
        </td>
      </tr>
      <tr>
        <td valign="top" style="text-align: left; padding-left: 20.0px; padding-bottom: 2.0px">
          Selling, general and administrative
        </td>
        <td>

        </td>
        <td>

        </td>
        <td style="border-bottom-width: 1.0pt; border-bottom-style: solid; border-bottom-color: black">
          &#160;
        </td>
        <td valign="bottom" style="padding-right: 0.0px; border-bottom-width: 1.0pt; text-align: right; padding-left: 0.0px; border-bottom-style: solid; border-bottom-color: black; white-space: nowrap">
          4,823
        </td>
        <td style="border-bottom-width: 1.0pt; border-bottom-style: solid; border-bottom-color: black">
          &#160;
        </td>
        <td>

        </td>
        <td>

        </td>
        <td style="border-bottom-width: 1.0pt; border-bottom-style: solid; border-bottom-color: black">
          &#160;
        </td>
        <td valign="bottom" style="padding-right: 0.0px; border-bottom-width: 1.0pt; text-align: right; padding-left: 0.0px; border-bottom-style: solid; border-bottom-color: black; white-space: nowrap">
          4,280
        </td>
        <td style="border-bottom-width: 1.0pt; border-bottom-style: solid; border-bottom-color: black">
          &#160;
        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td style="border-bottom-width: 1.0pt; border-bottom-style: solid; border-bottom-color: black">
          &#160;
        </td>
        <td valign="bottom" style="padding-right: 0.0px; border-bottom-width: 1.0pt; text-align: right; padding-left: 0.0px; border-bottom-style: solid; border-bottom-color: black; white-space: nowrap">
          14,862
        </td>
        <td>

        </td>
        <td>

        </td>
        <td style="border-bottom-width: 1.0pt; border-bottom-style: solid; border-bottom-color: black">
          &#160;
        </td>
        <td valign="bottom" style="padding-right: 0.0px; border-bottom-width: 1.0pt; text-align: right; padding-left: 0.0px; border-bottom-style: solid; border-bottom-color: black; white-space: nowrap">
          12,525
        </td>
      </tr>
      <tr>
        <td valign="top" style="text-align: left; padding-left: 0.0px; padding-bottom: 2.0px">
          Total operating expenses
        </td>
        <td>

        </td>
        <td>

        </td>
        <td style="border-bottom-width: 1.0pt; border-bottom-style: solid; border-bottom-color: black">
          &#160;
        </td>
        <td valign="bottom" style="padding-right: 0.0px; border-bottom-width: 1.0pt; text-align: right; padding-left: 0.0px; border-bottom-style: solid; border-bottom-color: black; white-space: nowrap">
          16,915
        </td>
        <td style="border-bottom-width: 1.0pt; border-bottom-style: solid; border-bottom-color: black">
          &#160;
        </td>
        <td>

        </td>
        <td>

        </td>
        <td style="border-bottom-width: 1.0pt; border-bottom-style: solid; border-bottom-color: black">
          &#160;
        </td>
        <td valign="bottom" style="padding-right: 0.0px; border-bottom-width: 1.0pt; text-align: right; padding-left: 0.0px; border-bottom-style: solid; border-bottom-color: black; white-space: nowrap">
          12,100
        </td>
        <td style="border-bottom-width: 1.0pt; border-bottom-style: solid; border-bottom-color: black">
          &#160;
        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td style="border-bottom-width: 1.0pt; border-bottom-style: solid; border-bottom-color: black">
          &#160;
        </td>
        <td valign="bottom" style="padding-right: 0.0px; border-bottom-width: 1.0pt; text-align: right; padding-left: 0.0px; border-bottom-style: solid; border-bottom-color: black; white-space: nowrap">
          48,031
        </td>
        <td>

        </td>
        <td>

        </td>
        <td style="border-bottom-width: 1.0pt; border-bottom-style: solid; border-bottom-color: black">
          &#160;
        </td>
        <td valign="bottom" style="padding-right: 0.0px; border-bottom-width: 1.0pt; text-align: right; padding-left: 0.0px; border-bottom-style: solid; border-bottom-color: black; white-space: nowrap">
          36,786
        </td>
      </tr>
      <tr>
        <td valign="top" style="text-align: left; padding-left: 0.0px">
          Income from operations
        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-right: 0.0px; text-align: right; padding-left: 0.0px; white-space: nowrap">
          10,269
        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-right: 0.0px; text-align: right; padding-left: 0.0px; white-space: nowrap">
          13,689
        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-right: 0.0px; text-align: right; padding-left: 0.0px; white-space: nowrap">
          36,001
        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-right: 0.0px; text-align: right; padding-left: 0.0px; white-space: nowrap">
          37,867
        </td>
      </tr>
      <tr>
        <td valign="top" style="text-align: left; padding-left: 20.0px; padding-bottom: 2.0px">
          Interest income, net
        </td>
        <td>

        </td>
        <td>

        </td>
        <td style="border-bottom-width: 1.0pt; border-bottom-style: solid; border-bottom-color: black">
          &#160;
        </td>
        <td valign="bottom" style="padding-right: 0.0px; border-bottom-width: 1.0pt; text-align: right; padding-left: 0.0px; border-bottom-style: solid; border-bottom-color: black; white-space: nowrap">
          261
        </td>
        <td style="border-bottom-width: 1.0pt; border-bottom-style: solid; border-bottom-color: black">
          &#160;
        </td>
        <td>

        </td>
        <td>

        </td>
        <td style="border-bottom-width: 1.0pt; border-bottom-style: solid; border-bottom-color: black">
          &#160;
        </td>
        <td valign="bottom" style="padding-right: 0.0px; border-bottom-width: 1.0pt; text-align: right; padding-left: 0.0px; border-bottom-style: solid; border-bottom-color: black; white-space: nowrap">
          93
        </td>
        <td style="border-bottom-width: 1.0pt; border-bottom-style: solid; border-bottom-color: black">
          &#160;
        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td style="border-bottom-width: 1.0pt; border-bottom-style: solid; border-bottom-color: black">
          &#160;
        </td>
        <td valign="bottom" style="padding-right: 0.0px; border-bottom-width: 1.0pt; text-align: right; padding-left: 0.0px; border-bottom-style: solid; border-bottom-color: black; white-space: nowrap">
          335
        </td>
        <td>

        </td>
        <td>

        </td>
        <td style="border-bottom-width: 1.0pt; border-bottom-style: solid; border-bottom-color: black">
          &#160;
        </td>
        <td valign="bottom" style="padding-right: 0.0px; border-bottom-width: 1.0pt; text-align: right; padding-left: 0.0px; border-bottom-style: solid; border-bottom-color: black; white-space: nowrap">
          214
        </td>
      </tr>
      <tr>
        <td valign="top" style="text-align: left; padding-left: 0.0px">
          Income before income taxes
        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-right: 0.0px; text-align: right; padding-left: 0.0px; white-space: nowrap">
          10,530
        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-right: 0.0px; text-align: right; padding-left: 0.0px; white-space: nowrap">
          13,782
        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-right: 0.0px; text-align: right; padding-left: 0.0px; white-space: nowrap">
          36,336
        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-right: 0.0px; text-align: right; padding-left: 0.0px; white-space: nowrap">
          38,081
        </td>
      </tr>
      <tr>
        <td valign="top" style="text-align: left; padding-left: 20.0px; padding-bottom: 2.0px">
          Provision for income taxes
        </td>
        <td>

        </td>
        <td>

        </td>
        <td style="border-bottom-width: 1.0pt; border-bottom-style: solid; border-bottom-color: black">
          &#160;
        </td>
        <td valign="bottom" style="padding-right: 0.0px; border-bottom-width: 1.0pt; text-align: right; padding-left: 0.0px; border-bottom-style: solid; border-bottom-color: black; white-space: nowrap">
          3,643
        </td>
        <td style="border-bottom-width: 1.0pt; border-bottom-style: solid; border-bottom-color: black">
          &#160;
        </td>
        <td>

        </td>
        <td>

        </td>
        <td style="border-bottom-width: 1.0pt; border-bottom-style: solid; border-bottom-color: black">
          &#160;
        </td>
        <td valign="bottom" style="padding-right: 0.0px; border-bottom-width: 1.0pt; text-align: right; padding-left: 0.0px; border-bottom-style: solid; border-bottom-color: black; white-space: nowrap">
          4,830
        </td>
        <td style="border-bottom-width: 1.0pt; border-bottom-style: solid; border-bottom-color: black">
          &#160;
        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td style="border-bottom-width: 1.0pt; border-bottom-style: solid; border-bottom-color: black">
          &#160;
        </td>
        <td valign="bottom" style="padding-right: 0.0px; border-bottom-width: 1.0pt; text-align: right; padding-left: 0.0px; border-bottom-style: solid; border-bottom-color: black; white-space: nowrap">
          12,587
        </td>
        <td>

        </td>
        <td>

        </td>
        <td style="border-bottom-width: 1.0pt; border-bottom-style: solid; border-bottom-color: black">
          &#160;
        </td>
        <td valign="bottom" style="padding-right: 0.0px; border-bottom-width: 1.0pt; text-align: right; padding-left: 0.0px; border-bottom-style: solid; border-bottom-color: black; white-space: nowrap">
          13,619
        </td>
      </tr>
      <tr>
        <td valign="top" style="text-align: left; padding-left: 0.0px; padding-bottom: 4.0px">
          Net income
        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-right: 0.0px; border-bottom-width: 2.25pt; text-align: right; padding-left: 0.0px; border-bottom-style: double; border-bottom-color: black; white-space: nowrap">
          $
        </td>
        <td valign="bottom" style="padding-right: 0.0px; border-bottom-width: 2.25pt; text-align: right; padding-left: 0.0px; border-bottom-style: double; border-bottom-color: black; white-space: nowrap">
          6,887
        </td>
        <td style="border-bottom-width: 2.25pt; border-bottom-style: double; border-bottom-color: black">
          &#160;
        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-right: 0.0px; border-bottom-width: 2.25pt; text-align: right; padding-left: 0.0px; border-bottom-style: double; border-bottom-color: black; white-space: nowrap">
          $
        </td>
        <td valign="bottom" style="padding-right: 0.0px; border-bottom-width: 2.25pt; text-align: right; padding-left: 0.0px; border-bottom-style: double; border-bottom-color: black; white-space: nowrap">
          8,952
        </td>
        <td style="border-bottom-width: 2.25pt; border-bottom-style: double; border-bottom-color: black">
          &#160;
        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-right: 0.0px; border-bottom-width: 2.25pt; text-align: right; padding-left: 0.0px; border-bottom-style: double; border-bottom-color: black; white-space: nowrap">
          $
        </td>
        <td valign="bottom" style="padding-right: 0.0px; border-bottom-width: 2.25pt; text-align: right; padding-left: 0.0px; border-bottom-style: double; border-bottom-color: black; white-space: nowrap">
          23,749
        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-right: 0.0px; border-bottom-width: 2.25pt; text-align: right; padding-left: 0.0px; border-bottom-style: double; border-bottom-color: black; white-space: nowrap">
          $
        </td>
        <td valign="bottom" style="padding-right: 0.0px; border-bottom-width: 2.25pt; text-align: right; padding-left: 0.0px; border-bottom-style: double; border-bottom-color: black; white-space: nowrap">
          24,462
        </td>
      </tr>
      <tr>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td colspan="3">

        </td>
        <td>

        </td>
        <td>

        </td>
        <td colspan="3">

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td colspan="2">

        </td>
        <td>

        </td>
        <td>

        </td>
        <td colspan="2">
          &#160;
        </td>
      </tr>
      <tr>
        <td valign="top" style="text-align: left; padding-left: 0.0px">
          Basic net income per share:
        </td>
        <td>

        </td>
        <td>

        </td>
        <td colspan="3">

        </td>
        <td>

        </td>
        <td>

        </td>
        <td colspan="3">

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td colspan="2">

        </td>
        <td>

        </td>
        <td>

        </td>
        <td colspan="2">

        </td>
      </tr>
      <tr>
        <td valign="top" style="text-align: left; padding-left: 20.0px">
          Net income
        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-right: 0.0px; text-align: right; padding-left: 0.0px; white-space: nowrap">
          $
        </td>
        <td valign="bottom" style="padding-right: 0.0px; text-align: right; padding-left: 0.0px; white-space: nowrap">
          0.47
        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-right: 0.0px; text-align: right; padding-left: 0.0px; white-space: nowrap">
          $
        </td>
        <td valign="bottom" style="padding-right: 0.0px; text-align: right; padding-left: 0.0px; white-space: nowrap">
          0.61
        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-right: 0.0px; text-align: right; padding-left: 0.0px; white-space: nowrap">
          $
        </td>
        <td valign="bottom" style="padding-right: 0.0px; text-align: right; padding-left: 0.0px; white-space: nowrap">
          1.63
        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-right: 0.0px; text-align: right; padding-left: 0.0px; white-space: nowrap">
          $
        </td>
        <td valign="bottom" style="padding-right: 0.0px; text-align: right; padding-left: 0.0px; white-space: nowrap">
          1.66
        </td>
      </tr>
      <tr>
        <td valign="top" style="text-align: left; padding-left: 20.0px">
          Basic weighted average common shares outstanding
        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-right: 0.0px; text-align: right; padding-left: 0.0px; white-space: nowrap">
          14,579
        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-right: 0.0px; text-align: right; padding-left: 0.0px; white-space: nowrap">
          14,625
        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-right: 0.0px; text-align: right; padding-left: 0.0px; white-space: nowrap">
          14,572
        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-right: 0.0px; text-align: right; padding-left: 0.0px; white-space: nowrap">
          14,726
        </td>
      </tr>
      <tr>
        <td valign="top" style="text-align: left; padding-left: 0.0px">
          Diluted net income per share:
        </td>
        <td>

        </td>
        <td>

        </td>
        <td colspan="3">

        </td>
        <td>

        </td>
        <td>

        </td>
        <td colspan="3">

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td colspan="2">

        </td>
        <td>

        </td>
        <td>

        </td>
        <td colspan="2">

        </td>
      </tr>
      <tr>
        <td valign="top" style="text-align: left; padding-left: 20.0px">
          Net income
        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-right: 0.0px; text-align: right; padding-left: 0.0px; white-space: nowrap">
          $
        </td>
        <td valign="bottom" style="padding-right: 0.0px; text-align: right; padding-left: 0.0px; white-space: nowrap">
          0.46
        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-right: 0.0px; text-align: right; padding-left: 0.0px; white-space: nowrap">
          $
        </td>
        <td valign="bottom" style="padding-right: 0.0px; text-align: right; padding-left: 0.0px; white-space: nowrap">
          0.59
        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-right: 0.0px; text-align: right; padding-left: 0.0px; white-space: nowrap">
          $
        </td>
        <td valign="bottom" style="padding-right: 0.0px; text-align: right; padding-left: 0.0px; white-space: nowrap">
          1.58
        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-right: 0.0px; text-align: right; padding-left: 0.0px; white-space: nowrap">
          $
        </td>
        <td valign="bottom" style="padding-right: 0.0px; text-align: right; padding-left: 0.0px; white-space: nowrap">
          1.61
        </td>
      </tr>
      <tr>
        <td valign="top" style="text-align: left; padding-left: 20.0px">
          Diluted weighted average common shares outstanding
        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-right: 0.0px; text-align: right; padding-left: 0.0px; white-space: nowrap">
          15,115
        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-right: 0.0px; text-align: right; padding-left: 0.0px; white-space: nowrap">
          15,077
        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-right: 0.0px; text-align: right; padding-left: 0.0px; white-space: nowrap">
          15,065
        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-right: 0.0px; text-align: right; padding-left: 0.0px; white-space: nowrap">
          15,163
        </td>
      </tr>
      <tr>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td colspan="3">

        </td>
        <td>

        </td>
        <td>

        </td>
        <td colspan="3">

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td colspan="2">

        </td>
        <td>

        </td>
        <td>

        </td>
        <td colspan="2">
          &#160;
        </td>
      </tr>
      <tr>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td colspan="3">

        </td>
        <td>

        </td>
        <td>

        </td>
        <td colspan="3">

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td colspan="2">

        </td>
        <td>

        </td>
        <td>

        </td>
        <td colspan="2">
          &#160;
        </td>
      </tr>
      <tr>
        <td colspan="11" valign="top" style="text-align: center; padding-left: 0.0px">
          <b>Anika Therapeutics, Inc. and Subsidiaries</b>
        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td colspan="2">

        </td>
        <td>

        </td>
        <td>

        </td>
        <td colspan="2">

        </td>
      </tr>
      <tr>
        <td colspan="11" valign="top" style="text-align: center; padding-left: 0.0px">
          <b>Condensed Consolidated Balance Sheets</b>
        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td colspan="2">

        </td>
        <td>

        </td>
        <td>

        </td>
        <td colspan="2">

        </td>
      </tr>
      <tr>
        <td colspan="11" valign="top" style="text-align: center; padding-left: 0.0px">
          <b>(in thousands, except per share data)</b>
        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td colspan="2">

        </td>
        <td>

        </td>
        <td>

        </td>
        <td colspan="2">

        </td>
      </tr>
      <tr>
        <td colspan="11" valign="top" style="text-align: center; padding-left: 0.0px">
          (unaudited)
        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td colspan="2">

        </td>
        <td>

        </td>
        <td>

        </td>
        <td colspan="2">

        </td>
      </tr>
      <tr>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td colspan="3">

        </td>
        <td>

        </td>
        <td>

        </td>
        <td colspan="3">

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td colspan="2">

        </td>
        <td>

        </td>
        <td>

        </td>
        <td colspan="2">
          &#160;
        </td>
      </tr>
      <tr>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td colspan="3" valign="top" style="text-align: center; padding-left: 0.0px">
          <b>September 30,</b>
        </td>
        <td>

        </td>
        <td>

        </td>
        <td colspan="3" valign="top" style="text-align: center; padding-left: 0.0px">
          <b>December 31,</b>
        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td colspan="2">

        </td>
        <td>

        </td>
        <td>

        </td>
        <td colspan="2">

        </td>
      </tr>
      <tr>
        <td valign="top" style="text-align: center; padding-left: 0.0px; padding-bottom: 2.0px">
          <b>ASSETS</b>
        </td>
        <td>

        </td>
        <td>

        </td>
        <td colspan="3" valign="bottom" style="padding-right: 0.0px; border-bottom-width: 1.0pt; text-align: center; padding-left: 0.0px; border-bottom-style: solid; border-bottom-color: black; white-space: nowrap">
          <b>2017</b>
        </td>
        <td>

        </td>
        <td>

        </td>
        <td colspan="3" valign="bottom" style="padding-right: 0.0px; border-bottom-width: 1.0pt; text-align: center; padding-left: 0.0px; border-bottom-style: solid; border-bottom-color: black; white-space: nowrap">
          <b>2016</b>
        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td colspan="2">

        </td>
        <td>

        </td>
        <td>

        </td>
        <td colspan="2">

        </td>
      </tr>
      <tr>
        <td valign="top" style="text-align: left; padding-left: 0.0px">
          Current assets:
        </td>
        <td>

        </td>
        <td>

        </td>
        <td colspan="3">

        </td>
        <td>

        </td>
        <td>

        </td>
        <td colspan="3">

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td colspan="2">

        </td>
        <td>

        </td>
        <td>

        </td>
        <td colspan="2">

        </td>
      </tr>
      <tr>
        <td valign="top" style="text-align: left; padding-left: 20.0px">
          Cash and cash equivalents
        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-right: 0.0px; text-align: right; padding-left: 0.0px; white-space: nowrap">
          $
        </td>
        <td valign="bottom" style="padding-right: 0.0px; text-align: right; padding-left: 0.0px; white-space: nowrap">
          126,960
        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-right: 0.0px; text-align: right; padding-left: 0.0px; white-space: nowrap">
          $
        </td>
        <td valign="bottom" style="padding-right: 0.0px; text-align: right; padding-left: 0.0px; white-space: nowrap">
          104,261
        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td colspan="2">

        </td>
        <td>

        </td>
        <td>

        </td>
        <td colspan="2">

        </td>
      </tr>
      <tr>
        <td valign="top" style="text-align: left; padding-left: 20.0px">
          Investments
        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-right: 0.0px; text-align: right; padding-left: 0.0px; white-space: nowrap">
          25,750
        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-right: 0.0px; text-align: right; padding-left: 0.0px; white-space: nowrap">
          20,500
        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td colspan="2">

        </td>
        <td>

        </td>
        <td>

        </td>
        <td colspan="2">

        </td>
      </tr>
      <tr>
        <td valign="top" style="text-align: left; padding-left: 20.0px">
          Accounts receivable, net of reserves of $217 and $194 at September
          31, 2017 and December 31, 2016, respectively
        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-right: 0.0px; text-align: right; padding-left: 0.0px; white-space: nowrap">
          23,804
        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-right: 0.0px; text-align: right; padding-left: 0.0px; white-space: nowrap">
          27,598
        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td colspan="2">

        </td>
        <td>

        </td>
        <td>

        </td>
        <td colspan="2">

        </td>
      </tr>
      <tr>
        <td valign="top" style="text-align: left; padding-left: 20.0px">
          Inventories, net
        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-right: 0.0px; text-align: right; padding-left: 0.0px; white-space: nowrap">
          20,252
        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-right: 0.0px; text-align: right; padding-left: 0.0px; white-space: nowrap">
          15,983
        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td colspan="2">

        </td>
        <td>

        </td>
        <td>

        </td>
        <td colspan="2">

        </td>
      </tr>
      <tr>
        <td valign="top" style="text-align: left; padding-left: 20.0px; padding-bottom: 2.0px">
          Prepaid expenses and other current assets
        </td>
        <td>

        </td>
        <td>

        </td>
        <td style="border-bottom-width: 1.0pt; border-bottom-style: solid; border-bottom-color: black">
          &#160;
        </td>
        <td valign="bottom" style="padding-right: 0.0px; border-bottom-width: 1.0pt; text-align: right; padding-left: 0.0px; border-bottom-style: solid; border-bottom-color: black; white-space: nowrap">
          2,268
        </td>
        <td style="border-bottom-width: 1.0pt; border-bottom-style: solid; border-bottom-color: black">
          &#160;
        </td>
        <td>

        </td>
        <td>

        </td>
        <td style="border-bottom-width: 1.0pt; border-bottom-style: solid; border-bottom-color: black">
          &#160;
        </td>
        <td valign="bottom" style="padding-right: 0.0px; border-bottom-width: 1.0pt; text-align: right; padding-left: 0.0px; border-bottom-style: solid; border-bottom-color: black; white-space: nowrap">
          2,098
        </td>
        <td style="border-bottom-width: 1.0pt; border-bottom-style: solid; border-bottom-color: black">
          &#160;
        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td colspan="2">

        </td>
        <td>

        </td>
        <td>

        </td>
        <td colspan="2">

        </td>
      </tr>
      <tr>
        <td valign="top" style="text-align: left; padding-left: 40.0px">
          Total current assets
        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-right: 0.0px; text-align: right; padding-left: 0.0px; white-space: nowrap">
          199,034
        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-right: 0.0px; text-align: right; padding-left: 0.0px; white-space: nowrap">
          170,440
        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td colspan="2">

        </td>
        <td>

        </td>
        <td>

        </td>
        <td colspan="2">

        </td>
      </tr>
      <tr>
        <td valign="top" style="text-align: left; padding-left: 0.0px">
          Property and equipment, net
        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-right: 0.0px; text-align: right; padding-left: 0.0px; white-space: nowrap">
          53,973
        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-right: 0.0px; text-align: right; padding-left: 0.0px; white-space: nowrap">
          52,296
        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td colspan="2">

        </td>
        <td>

        </td>
        <td>

        </td>
        <td colspan="2">

        </td>
      </tr>
      <tr>
        <td valign="top" style="text-align: left; padding-left: 0.0px">
          Other long-term assets
        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-right: 0.0px; text-align: right; padding-left: 0.0px; white-space: nowrap">
          1,283
        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-right: 0.0px; text-align: right; padding-left: 0.0px; white-space: nowrap">
          69
        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td colspan="2">

        </td>
        <td>

        </td>
        <td>

        </td>
        <td colspan="2">

        </td>
      </tr>
      <tr>
        <td valign="top" style="text-align: left; padding-left: 0.0px">
          Intangible assets, net
        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-right: 0.0px; text-align: right; padding-left: 0.0px; white-space: nowrap">
          10,738
        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-right: 0.0px; text-align: right; padding-left: 0.0px; white-space: nowrap">
          10,227
        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td colspan="2">

        </td>
        <td>

        </td>
        <td>

        </td>
        <td colspan="2">

        </td>
      </tr>
      <tr>
        <td valign="top" style="text-align: left; padding-left: 0.0px; padding-bottom: 2.0px">
          Goodwill
        </td>
        <td>

        </td>
        <td>

        </td>
        <td style="border-bottom-width: 1.0pt; border-bottom-style: solid; border-bottom-color: black">
          &#160;
        </td>
        <td valign="bottom" style="padding-right: 0.0px; border-bottom-width: 1.0pt; text-align: right; padding-left: 0.0px; border-bottom-style: solid; border-bottom-color: black; white-space: nowrap">
          8,104
        </td>
        <td style="border-bottom-width: 1.0pt; border-bottom-style: solid; border-bottom-color: black">
          &#160;
        </td>
        <td>

        </td>
        <td>

        </td>
        <td style="border-bottom-width: 1.0pt; border-bottom-style: solid; border-bottom-color: black">
          &#160;
        </td>
        <td valign="bottom" style="padding-right: 0.0px; border-bottom-width: 1.0pt; text-align: right; padding-left: 0.0px; border-bottom-style: solid; border-bottom-color: black; white-space: nowrap">
          7,214
        </td>
        <td style="border-bottom-width: 1.0pt; border-bottom-style: solid; border-bottom-color: black">
          &#160;
        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td colspan="2">

        </td>
        <td>

        </td>
        <td>

        </td>
        <td colspan="2">

        </td>
      </tr>
      <tr>
        <td valign="top" style="text-align: left; padding-left: 0.0px; padding-bottom: 4.0px">
          Total assets
        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-right: 0.0px; border-bottom-width: 2.25pt; text-align: right; padding-left: 0.0px; border-bottom-style: double; border-bottom-color: black; white-space: nowrap">
          $
        </td>
        <td valign="bottom" style="padding-right: 0.0px; border-bottom-width: 2.25pt; text-align: right; padding-left: 0.0px; border-bottom-style: double; border-bottom-color: black; white-space: nowrap">
          273,132
        </td>
        <td style="border-bottom-width: 2.25pt; border-bottom-style: double; border-bottom-color: black">
          &#160;
        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-right: 0.0px; border-bottom-width: 2.25pt; text-align: right; padding-left: 0.0px; border-bottom-style: double; border-bottom-color: black; white-space: nowrap">
          $
        </td>
        <td valign="bottom" style="padding-right: 0.0px; border-bottom-width: 2.25pt; text-align: right; padding-left: 0.0px; border-bottom-style: double; border-bottom-color: black; white-space: nowrap">
          240,246
        </td>
        <td style="border-bottom-width: 2.25pt; border-bottom-style: double; border-bottom-color: black">
          &#160;
        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td colspan="2">

        </td>
        <td>

        </td>
        <td>

        </td>
        <td colspan="2">

        </td>
      </tr>
      <tr>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td colspan="3">

        </td>
        <td>

        </td>
        <td>

        </td>
        <td colspan="3">

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td colspan="2">

        </td>
        <td>

        </td>
        <td>

        </td>
        <td colspan="2">
          &#160;
        </td>
      </tr>
      <tr>
        <td valign="top" style="text-align: center; padding-left: 0.0px">
          <b>LIABILITIES AND STOCKHOLDERS&#8217; EQUITY</b>
        </td>
        <td>

        </td>
        <td>

        </td>
        <td colspan="3">

        </td>
        <td>

        </td>
        <td>

        </td>
        <td colspan="3">

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td colspan="2">

        </td>
        <td>

        </td>
        <td>

        </td>
        <td colspan="2">

        </td>
      </tr>
      <tr>
        <td valign="top" style="text-align: left; padding-left: 0.0px">
          Current liabilities:
        </td>
        <td>

        </td>
        <td>

        </td>
        <td colspan="3">

        </td>
        <td>

        </td>
        <td>

        </td>
        <td colspan="3">

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td colspan="2">

        </td>
        <td>

        </td>
        <td>

        </td>
        <td colspan="2">

        </td>
      </tr>
      <tr>
        <td valign="top" style="text-align: left; padding-left: 20.0px">
          Accounts payable
        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-right: 0.0px; text-align: right; padding-left: 0.0px; white-space: nowrap">
          $
        </td>
        <td valign="bottom" style="padding-right: 0.0px; text-align: right; padding-left: 0.0px; white-space: nowrap">
          5,189
        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-right: 0.0px; text-align: right; padding-left: 0.0px; white-space: nowrap">
          $
        </td>
        <td valign="bottom" style="padding-right: 0.0px; text-align: right; padding-left: 0.0px; white-space: nowrap">
          2,303
        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td colspan="2">

        </td>
        <td>

        </td>
        <td>

        </td>
        <td colspan="2">

        </td>
      </tr>
      <tr>
        <td valign="top" style="text-align: left; padding-left: 20.0px; padding-bottom: 2.0px">
          Accrued expenses and other current liabilities
        </td>
        <td>

        </td>
        <td>

        </td>
        <td style="border-bottom-width: 1.0pt; border-bottom-style: solid; border-bottom-color: black">
          &#160;
        </td>
        <td valign="bottom" style="padding-right: 0.0px; border-bottom-width: 1.0pt; text-align: right; padding-left: 0.0px; border-bottom-style: solid; border-bottom-color: black; white-space: nowrap">
          6,516
        </td>
        <td style="border-bottom-width: 1.0pt; border-bottom-style: solid; border-bottom-color: black">
          &#160;
        </td>
        <td>

        </td>
        <td>

        </td>
        <td style="border-bottom-width: 1.0pt; border-bottom-style: solid; border-bottom-color: black">
          &#160;
        </td>
        <td valign="bottom" style="padding-right: 0.0px; border-bottom-width: 1.0pt; text-align: right; padding-left: 0.0px; border-bottom-style: solid; border-bottom-color: black; white-space: nowrap">
          6,496
        </td>
        <td style="border-bottom-width: 1.0pt; border-bottom-style: solid; border-bottom-color: black">
          &#160;
        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td colspan="2">

        </td>
        <td>

        </td>
        <td>

        </td>
        <td colspan="2">

        </td>
      </tr>
      <tr>
        <td valign="top" style="text-align: left; padding-left: 40.0px; padding-bottom: 2.0px">
          Total current liabilities
        </td>
        <td>

        </td>
        <td>

        </td>
        <td style="border-bottom-width: 1.0pt; border-bottom-style: solid; border-bottom-color: black">
          &#160;
        </td>
        <td valign="bottom" style="padding-right: 0.0px; border-bottom-width: 1.0pt; text-align: right; padding-left: 0.0px; border-bottom-style: solid; border-bottom-color: black; white-space: nowrap">
          11,705
        </td>
        <td style="border-bottom-width: 1.0pt; border-bottom-style: solid; border-bottom-color: black">
          &#160;
        </td>
        <td>

        </td>
        <td>

        </td>
        <td style="border-bottom-width: 1.0pt; border-bottom-style: solid; border-bottom-color: black">
          &#160;
        </td>
        <td valign="bottom" style="padding-right: 0.0px; border-bottom-width: 1.0pt; text-align: right; padding-left: 0.0px; border-bottom-style: solid; border-bottom-color: black; white-space: nowrap">
          8,799
        </td>
        <td style="border-bottom-width: 1.0pt; border-bottom-style: solid; border-bottom-color: black">
          &#160;
        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td colspan="2">

        </td>
        <td>

        </td>
        <td>

        </td>
        <td colspan="2">

        </td>
      </tr>
      <tr>
        <td valign="top" style="text-align: left; padding-left: 0.0px">
          Other long-term liabilities
        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-right: 0.0px; text-align: right; padding-left: 0.0px; white-space: nowrap">
          545
        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-right: 0.0px; text-align: right; padding-left: 0.0px; white-space: nowrap">
          2,126
        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td colspan="2">

        </td>
        <td>

        </td>
        <td>

        </td>
        <td colspan="2">

        </td>
      </tr>
      <tr>
        <td valign="top" style="text-align: left; padding-left: 0.0px">
          Deferred tax liability
        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-right: 0.0px; text-align: right; padding-left: 0.0px; white-space: nowrap">
          7,593
        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-right: 0.0px; text-align: right; padding-left: 0.0px; white-space: nowrap">
          6,548
        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td colspan="2">

        </td>
        <td>

        </td>
        <td>

        </td>
        <td colspan="2">

        </td>
      </tr>
      <tr>
        <td valign="top" style="text-align: left; padding-left: 0.0px">
          Commitments and contingencies
        </td>
        <td>

        </td>
        <td>

        </td>
        <td colspan="3">

        </td>
        <td>

        </td>
        <td>

        </td>
        <td colspan="3">

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td colspan="2">

        </td>
        <td>

        </td>
        <td>

        </td>
        <td colspan="2">

        </td>
      </tr>
      <tr>
        <td valign="top" style="text-align: left; padding-left: 0.0px">
          Stockholders&#8217; equity:
        </td>
        <td>

        </td>
        <td>

        </td>
        <td colspan="3">

        </td>
        <td>

        </td>
        <td>

        </td>
        <td colspan="3">

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td colspan="2">

        </td>
        <td>

        </td>
        <td>

        </td>
        <td colspan="2">

        </td>
      </tr>
      <tr>
        <td valign="top" style="text-align: left; padding-left: 20.0px">
          Preferred stock, $0.01 par value; 1,250 shares authorized, no shares
          issued and outstanding at September 30, 2017 and December 31, 2016,
          respectively
        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-right: 0.0px; text-align: right; padding-left: 0.0px; white-space: nowrap">
          -
        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-right: 0.0px; text-align: right; padding-left: 0.0px; white-space: nowrap">
          -
        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td colspan="2">

        </td>
        <td>

        </td>
        <td>

        </td>
        <td colspan="2">

        </td>
      </tr>
      <tr>
        <td valign="top" style="text-align: left; padding-left: 20.0px">
          Common stock, $0.01 par value; 60,000 shares authorized, 14,662 and
          14,627 shares issued and outstanding at September 30, 2017 and
          December 31, 2016, respectively
        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-right: 0.0px; text-align: right; padding-left: 0.0px; white-space: nowrap">
          146
        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-right: 0.0px; text-align: right; padding-left: 0.0px; white-space: nowrap">
          146
        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td colspan="2">

        </td>
        <td>

        </td>
        <td>

        </td>
        <td colspan="2">

        </td>
      </tr>
      <tr>
        <td valign="top" style="text-align: left; padding-left: 20.0px">
          Additional paid-in-capital
        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-right: 0.0px; text-align: right; padding-left: 0.0px; white-space: nowrap">
          66,746
        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-right: 0.0px; text-align: right; padding-left: 0.0px; white-space: nowrap">
          61,735
        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td colspan="2">

        </td>
        <td>

        </td>
        <td>

        </td>
        <td colspan="2">

        </td>
      </tr>
      <tr>
        <td valign="top" style="text-align: left; padding-left: 20.0px">
          Accumulated other comprehensive loss
        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-right: 0.0px; text-align: right; padding-left: 0.0px; white-space: nowrap">
          (5,047
        </td>
        <td valign="bottom" style="padding-right: 0.0px; text-align: left; padding-left: 0.0px; white-space: nowrap">
          )
        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-right: 0.0px; text-align: right; padding-left: 0.0px; white-space: nowrap">
          (7,317
        </td>
        <td valign="bottom" style="padding-right: 0.0px; text-align: left; padding-left: 0.0px; white-space: nowrap">
          )
        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td colspan="2">

        </td>
        <td>

        </td>
        <td>

        </td>
        <td colspan="2">

        </td>
      </tr>
      <tr>
        <td valign="top" style="text-align: left; padding-left: 20.0px; padding-bottom: 2.0px">
          Retained earnings
        </td>
        <td>

        </td>
        <td>

        </td>
        <td style="border-bottom-width: 1.0pt; border-bottom-style: solid; border-bottom-color: black">
          &#160;
        </td>
        <td valign="bottom" style="padding-right: 0.0px; border-bottom-width: 1.0pt; text-align: right; padding-left: 0.0px; border-bottom-style: solid; border-bottom-color: black; white-space: nowrap">
          191,444
        </td>
        <td style="border-bottom-width: 1.0pt; border-bottom-style: solid; border-bottom-color: black">
          &#160;
        </td>
        <td>

        </td>
        <td>

        </td>
        <td style="border-bottom-width: 1.0pt; border-bottom-style: solid; border-bottom-color: black">
          &#160;
        </td>
        <td valign="bottom" style="padding-right: 0.0px; border-bottom-width: 1.0pt; text-align: right; padding-left: 0.0px; border-bottom-style: solid; border-bottom-color: black; white-space: nowrap">
          168,209
        </td>
        <td style="border-bottom-width: 1.0pt; border-bottom-style: solid; border-bottom-color: black">
          &#160;
        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td colspan="2">

        </td>
        <td>

        </td>
        <td>

        </td>
        <td colspan="2">

        </td>
      </tr>
      <tr>
        <td valign="top" style="text-align: left; padding-left: 40.0px; padding-bottom: 2.0px">
          <p style="margin-bottom: 0px; margin-top: 0px">
            Total stockholders&#8217; equity
          </p>
        </td>
        <td>

        </td>
        <td>

        </td>
        <td style="border-bottom-width: 1.0pt; border-bottom-style: solid; border-bottom-color: black">
          &#160;
        </td>
        <td valign="bottom" style="padding-right: 0.0px; border-bottom-width: 1.0pt; text-align: right; padding-left: 0.0px; border-bottom-style: solid; border-bottom-color: black; white-space: nowrap">
          253,289
        </td>
        <td style="border-bottom-width: 1.0pt; border-bottom-style: solid; border-bottom-color: black">
          &#160;
        </td>
        <td>

        </td>
        <td>

        </td>
        <td style="border-bottom-width: 1.0pt; border-bottom-style: solid; border-bottom-color: black">
          &#160;
        </td>
        <td valign="bottom" style="padding-right: 0.0px; border-bottom-width: 1.0pt; text-align: right; padding-left: 0.0px; border-bottom-style: solid; border-bottom-color: black; white-space: nowrap">
          222,773
        </td>
        <td style="border-bottom-width: 1.0pt; border-bottom-style: solid; border-bottom-color: black">
          &#160;
        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td colspan="2">

        </td>
        <td>

        </td>
        <td>

        </td>
        <td colspan="2">

        </td>
      </tr>
      <tr>
        <td valign="top" style="text-align: left; padding-left: 0.0px; padding-bottom: 4.0px">
          Total liabilities and stockholders&#8217; equity
        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-right: 0.0px; border-bottom-width: 2.25pt; text-align: right; padding-left: 0.0px; border-bottom-style: double; border-bottom-color: black; white-space: nowrap">
          $
        </td>
        <td valign="bottom" style="padding-right: 0.0px; border-bottom-width: 2.25pt; text-align: right; padding-left: 0.0px; border-bottom-style: double; border-bottom-color: black; white-space: nowrap">
          273,132
        </td>
        <td style="border-bottom-width: 2.25pt; border-bottom-style: double; border-bottom-color: black">
          &#160;
        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-right: 0.0px; border-bottom-width: 2.25pt; text-align: right; padding-left: 0.0px; border-bottom-style: double; border-bottom-color: black; white-space: nowrap">
          $
        </td>
        <td valign="bottom" style="padding-right: 0.0px; border-bottom-width: 2.25pt; text-align: right; padding-left: 0.0px; border-bottom-style: double; border-bottom-color: black; white-space: nowrap">
          240,246
        </td>
        <td style="border-bottom-width: 2.25pt; border-bottom-style: double; border-bottom-color: black">
          &#160;
        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td colspan="2">

        </td>
        <td>

        </td>
        <td>

        </td>
        <td colspan="2">

        </td>
      </tr>
      <tr>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td colspan="3">

        </td>
        <td>

        </td>
        <td>

        </td>
        <td colspan="3">

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td colspan="2">

        </td>
        <td>

        </td>
        <td>

        </td>
        <td colspan="2">
          &#160;
        </td>
      </tr>
    </table>
    </div>
    <div style="margin-left: 0pt; width: 100%; margin-bottom: 10pt; text-indent: 0pt; margin-right: 0pt">
      <div>
        <div style="text-align: left">

        </div>
      </div>
      <div style="page-break-after: always">
        <div style="text-align: center">

        </div>
        <div style="text-align: center">
          <hr style="color: black; height: 1.5pt">

        </div>
      </div>
      <div>
        <div style="text-align: right">

        </div>
      </div>
    </div>
<div style="text-align:left">
    <table cellspacing="0" style="width: 100%; font-family: Times New Roman; margin-bottom: 10.0px; font-size: 8pt">
      <tr>
        <td>

        </td>
        <td>
          &#160;
        </td>
        <td>
          &#160;
        </td>
        <td colspan="3">

        </td>
        <td colspan="2">

        </td>
        <td>
          &#160;
        </td>
        <td>
          &#160;
        </td>
        <td colspan="3">

        </td>
        <td colspan="2">

        </td>
        <td>

        </td>
        <td>
          &#160;
        </td>
        <td>
          &#160;
        </td>
        <td colspan="3">

        </td>
        <td colspan="2">

        </td>
        <td>
          &#160;
        </td>
        <td>
          &#160;
        </td>
        <td colspan="3">

        </td>
        <td colspan="2">

        </td>
      </tr>
      <tr>
        <td colspan="30" valign="top" style="text-align: center; padding-left: 0.0px">
          <b>Anika Therapeutics, Inc. and Subsidiaries</b>
        </td>
      </tr>
      <tr>
        <td colspan="30" valign="top" style="text-align: center; padding-left: 0.0px">
          <b>Supplemental Financial Data</b>
        </td>
      </tr>
      <tr>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td colspan="3">

        </td>
        <td colspan="2">

        </td>
        <td>

        </td>
        <td>

        </td>
        <td colspan="3">

        </td>
        <td colspan="2">

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td colspan="3">

        </td>
        <td colspan="2">

        </td>
        <td>

        </td>
        <td>

        </td>
        <td colspan="3">

        </td>
        <td colspan="2">
          &#160;
        </td>
      </tr>
      <tr>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td colspan="3">

        </td>
        <td colspan="2">

        </td>
        <td>

        </td>
        <td>

        </td>
        <td colspan="3">

        </td>
        <td colspan="2">

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td colspan="3">

        </td>
        <td colspan="2">

        </td>
        <td>

        </td>
        <td>

        </td>
        <td colspan="3">

        </td>
        <td colspan="2">
          &#160;
        </td>
      </tr>
      <tr>
        <td colspan="30" valign="top" style="text-align: center; padding-left: 0.0px">
          <b>Revenue by Product Line and Product Gross Margin</b>
        </td>
      </tr>
      <tr>
        <td colspan="30" valign="top" style="text-align: center; padding-left: 0.0px">
          <b>(in thousands, except percentages)</b>
        </td>
      </tr>
      <tr>
        <td colspan="30" valign="top" style="text-align: center; padding-left: 0.0px">
          (unaudited)
        </td>
      </tr>
      <tr>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td colspan="3">

        </td>
        <td colspan="2">

        </td>
        <td>

        </td>
        <td>

        </td>
        <td colspan="3">

        </td>
        <td colspan="2">

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td colspan="3">

        </td>
        <td colspan="2">

        </td>
        <td>

        </td>
        <td>

        </td>
        <td colspan="3">

        </td>
        <td colspan="2">
          &#160;
        </td>
      </tr>
      <tr>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td colspan="13" valign="top" style="border-bottom-width: 1.0pt; text-align: center; padding-left: 0.0px; border-bottom-style: solid; border-bottom-color: black">
          <b>For the Three Months Ended September 30,</b>
        </td>
        <td>

        </td>
        <td>

        </td>
        <td colspan="12" valign="top" style="border-bottom-width: 1.0pt; text-align: center; padding-left: 0.0px; border-bottom-style: solid; border-bottom-color: black">
          <b>For the Nine Months Ended September 30,</b>
        </td>
      </tr>
      <tr>
        <td valign="top" style="text-align: left; padding-left: 0.0px; padding-bottom: 2.0px">
          <b>Product Line:</b>
        </td>
        <td>

        </td>
        <td>

        </td>
        <td colspan="2" valign="bottom" style="padding-right: 0.0px; border-bottom-width: 1.0pt; text-align: center; padding-left: 0.0px; border-bottom-style: solid; border-bottom-color: black; white-space: nowrap">
          <b>2017</b>
        </td>
        <td style="border-bottom-width: 1.0pt; border-bottom-style: solid; border-bottom-color: black">
          &#160;
        </td>
        <td colspan="2" valign="bottom" style="padding-right: 0.0px; border-bottom-width: 1.0pt; text-align: center; padding-left: 0.0px; border-bottom-style: solid; border-bottom-color: black; white-space: nowrap">
          <b>%</b>
        </td>
        <td>

        </td>
        <td>

        </td>
        <td colspan="2" valign="bottom" style="padding-right: 0.0px; border-bottom-width: 1.0pt; text-align: center; padding-left: 0.0px; border-bottom-style: solid; border-bottom-color: black; white-space: nowrap">
          <b>2016</b>
        </td>
        <td style="border-bottom-width: 1.0pt; border-bottom-style: solid; border-bottom-color: black">
          &#160;
        </td>
        <td colspan="2" valign="bottom" style="padding-right: 0.0px; border-bottom-width: 1.0pt; text-align: center; padding-left: 0.0px; border-bottom-style: solid; border-bottom-color: black; white-space: nowrap">
          <b>%</b>
        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td colspan="2" valign="bottom" style="padding-right: 0.0px; border-bottom-width: 1.0pt; text-align: center; padding-left: 0.0px; border-bottom-style: solid; border-bottom-color: black; white-space: nowrap">
          <b>2017</b>
        </td>
        <td style="border-bottom-width: 1.0pt; border-bottom-style: solid; border-bottom-color: black">
          &#160;
        </td>
        <td colspan="2" valign="bottom" style="padding-right: 0.0px; border-bottom-width: 1.0pt; text-align: center; padding-left: 0.0px; border-bottom-style: solid; border-bottom-color: black; white-space: nowrap">
          <b>%</b>
        </td>
        <td>

        </td>
        <td>

        </td>
        <td colspan="2" valign="bottom" style="padding-right: 0.0px; border-bottom-width: 1.0pt; text-align: center; padding-left: 0.0px; border-bottom-style: solid; border-bottom-color: black; white-space: nowrap">
          <b>2016</b>
        </td>
        <td style="border-bottom-width: 1.0pt; border-bottom-style: solid; border-bottom-color: black">
          &#160;
        </td>
        <td colspan="2" valign="bottom" style="padding-right: 0.0px; border-bottom-width: 1.0pt; text-align: center; padding-left: 0.0px; border-bottom-style: solid; border-bottom-color: black; white-space: nowrap">
          <b>%</b>
        </td>
      </tr>
      <tr>
        <td valign="top" style="text-align: left; padding-left: 20.0px">
          Orthobiologics
        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-right: 0.0px; text-align: right; padding-left: 0.0px; white-space: nowrap">
          $
        </td>
        <td valign="bottom" style="padding-right: 0.0px; text-align: right; padding-left: 0.0px; white-space: nowrap">
          23,990
        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-right: 0.0px; text-align: right; padding-left: 0.0px; white-space: nowrap">
          88
        </td>
        <td valign="bottom" style="padding-right: 0.0px; text-align: left; padding-left: 0.0px; white-space: nowrap">
          %
        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-right: 0.0px; text-align: right; padding-left: 0.0px; white-space: nowrap">
          $
        </td>
        <td valign="bottom" style="padding-right: 0.0px; text-align: right; padding-left: 0.0px; white-space: nowrap">
          22,428
        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-right: 0.0px; text-align: right; padding-left: 0.0px; white-space: nowrap">
          87
        </td>
        <td valign="bottom" style="padding-right: 0.0px; text-align: left; padding-left: 0.0px; white-space: nowrap">
          %
        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-right: 0.0px; text-align: right; padding-left: 0.0px; white-space: nowrap">
          $
        </td>
        <td valign="bottom" style="padding-right: 0.0px; text-align: right; padding-left: 0.0px; white-space: nowrap">
          68,686
        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-right: 0.0px; text-align: right; padding-left: 0.0px; white-space: nowrap">
          87
        </td>
        <td valign="bottom" style="padding-right: 0.0px; text-align: left; padding-left: 0.0px; white-space: nowrap">
          %
        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-right: 0.0px; text-align: right; padding-left: 0.0px; white-space: nowrap">
          $
        </td>
        <td valign="bottom" style="padding-right: 0.0px; text-align: right; padding-left: 0.0px; white-space: nowrap">
          65,319
        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-right: 0.0px; text-align: right; padding-left: 0.0px; white-space: nowrap">
          88
        </td>
        <td valign="bottom" style="padding-right: 0.0px; text-align: left; padding-left: 0.0px; white-space: nowrap">
          %
        </td>
      </tr>
      <tr>
        <td valign="top" style="text-align: left; padding-left: 20.0px">
          Surgical
        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-right: 0.0px; text-align: right; padding-left: 0.0px; white-space: nowrap">
          1,765
        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-right: 0.0px; text-align: right; padding-left: 0.0px; white-space: nowrap">
          7
        </td>
        <td valign="bottom" style="padding-right: 0.0px; text-align: left; padding-left: 0.0px; white-space: nowrap">
          %
        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-right: 0.0px; text-align: right; padding-left: 0.0px; white-space: nowrap">
          1,173
        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-right: 0.0px; text-align: right; padding-left: 0.0px; white-space: nowrap">
          5
        </td>
        <td valign="bottom" style="padding-right: 0.0px; text-align: left; padding-left: 0.0px; white-space: nowrap">
          %
        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-right: 0.0px; text-align: right; padding-left: 0.0px; white-space: nowrap">
          4,395
        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-right: 0.0px; text-align: right; padding-left: 0.0px; white-space: nowrap">
          6
        </td>
        <td valign="bottom" style="padding-right: 0.0px; text-align: left; padding-left: 0.0px; white-space: nowrap">
          %
        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-right: 0.0px; text-align: right; padding-left: 0.0px; white-space: nowrap">
          3,924
        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-right: 0.0px; text-align: right; padding-left: 0.0px; white-space: nowrap">
          5
        </td>
        <td valign="bottom" style="padding-right: 0.0px; text-align: left; padding-left: 0.0px; white-space: nowrap">
          %
        </td>
      </tr>
      <tr>
        <td valign="top" style="text-align: left; padding-left: 20.0px">
          Dermal
        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-right: 0.0px; text-align: right; padding-left: 0.0px; white-space: nowrap">
          358
        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-right: 0.0px; text-align: right; padding-left: 0.0px; white-space: nowrap">
          1
        </td>
        <td valign="bottom" style="padding-right: 0.0px; text-align: left; padding-left: 0.0px; white-space: nowrap">
          %
        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-right: 0.0px; text-align: right; padding-left: 0.0px; white-space: nowrap">
          594
        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-right: 0.0px; text-align: right; padding-left: 0.0px; white-space: nowrap">
          2
        </td>
        <td valign="bottom" style="padding-right: 0.0px; text-align: left; padding-left: 0.0px; white-space: nowrap">
          %
        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-right: 0.0px; text-align: right; padding-left: 0.0px; white-space: nowrap">
          1,235
        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-right: 0.0px; text-align: right; padding-left: 0.0px; white-space: nowrap">
          2
        </td>
        <td valign="bottom" style="padding-right: 0.0px; text-align: left; padding-left: 0.0px; white-space: nowrap">
          %
        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-right: 0.0px; text-align: right; padding-left: 0.0px; white-space: nowrap">
          1,558
        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-right: 0.0px; text-align: right; padding-left: 0.0px; white-space: nowrap">
          2
        </td>
        <td valign="bottom" style="padding-right: 0.0px; text-align: left; padding-left: 0.0px; white-space: nowrap">
          %
        </td>
      </tr>
      <tr>
        <td valign="top" style="text-align: left; padding-left: 20.0px; padding-bottom: 2.0px">
          Other
        </td>
        <td>

        </td>
        <td>

        </td>
        <td style="border-bottom-width: 1.0pt; border-bottom-style: solid; border-bottom-color: black">
          &#160;
        </td>
        <td valign="bottom" style="padding-right: 0.0px; border-bottom-width: 1.0pt; text-align: right; padding-left: 0.0px; border-bottom-style: solid; border-bottom-color: black; white-space: nowrap">
          1,065
        </td>
        <td style="border-bottom-width: 1.0pt; border-bottom-style: solid; border-bottom-color: black">
          &#160;
        </td>
        <td valign="bottom" style="padding-right: 0.0px; border-bottom-width: 1.0pt; text-align: right; padding-left: 0.0px; border-bottom-style: solid; border-bottom-color: black; white-space: nowrap">
          4
        </td>
        <td valign="bottom" style="padding-right: 0.0px; border-bottom-width: 1.0pt; text-align: left; padding-left: 0.0px; border-bottom-style: solid; border-bottom-color: black; white-space: nowrap">
          %
        </td>
        <td>

        </td>
        <td>

        </td>
        <td style="border-bottom-width: 1.0pt; border-bottom-style: solid; border-bottom-color: black">
          &#160;
        </td>
        <td valign="bottom" style="padding-right: 0.0px; border-bottom-width: 1.0pt; text-align: right; padding-left: 0.0px; border-bottom-style: solid; border-bottom-color: black; white-space: nowrap">
          1,588
        </td>
        <td style="border-bottom-width: 1.0pt; border-bottom-style: solid; border-bottom-color: black">
          &#160;
        </td>
        <td valign="bottom" style="padding-right: 0.0px; border-bottom-width: 1.0pt; text-align: right; padding-left: 0.0px; border-bottom-style: solid; border-bottom-color: black; white-space: nowrap">
          6
        </td>
        <td valign="bottom" style="padding-right: 0.0px; border-bottom-width: 1.0pt; text-align: left; padding-left: 0.0px; border-bottom-style: solid; border-bottom-color: black; white-space: nowrap">
          %
        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td style="border-bottom-width: 1.0pt; border-bottom-style: solid; border-bottom-color: black">
          &#160;
        </td>
        <td valign="bottom" style="padding-right: 0.0px; border-bottom-width: 1.0pt; text-align: right; padding-left: 0.0px; border-bottom-style: solid; border-bottom-color: black; white-space: nowrap">
          4,583
        </td>
        <td style="border-bottom-width: 1.0pt; border-bottom-style: solid; border-bottom-color: black">
          &#160;
        </td>
        <td valign="bottom" style="padding-right: 0.0px; border-bottom-width: 1.0pt; text-align: right; padding-left: 0.0px; border-bottom-style: solid; border-bottom-color: black; white-space: nowrap">
          5
        </td>
        <td valign="bottom" style="padding-right: 0.0px; border-bottom-width: 1.0pt; text-align: left; padding-left: 0.0px; border-bottom-style: solid; border-bottom-color: black; white-space: nowrap">
          %
        </td>
        <td>

        </td>
        <td>

        </td>
        <td style="border-bottom-width: 1.0pt; border-bottom-style: solid; border-bottom-color: black">
          &#160;
        </td>
        <td valign="bottom" style="padding-right: 0.0px; border-bottom-width: 1.0pt; text-align: right; padding-left: 0.0px; border-bottom-style: solid; border-bottom-color: black; white-space: nowrap">
          3,835
        </td>
        <td style="border-bottom-width: 1.0pt; border-bottom-style: solid; border-bottom-color: black">
          &#160;
        </td>
        <td valign="bottom" style="padding-right: 0.0px; border-bottom-width: 1.0pt; text-align: right; padding-left: 0.0px; border-bottom-style: solid; border-bottom-color: black; white-space: nowrap">
          5
        </td>
        <td valign="bottom" style="padding-right: 0.0px; border-bottom-width: 1.0pt; text-align: left; padding-left: 0.0px; border-bottom-style: solid; border-bottom-color: black; white-space: nowrap">
          %
        </td>
      </tr>
      <tr>
        <td valign="top" style="text-align: left; padding-left: 20.0px; padding-bottom: 4.0px">
          Product Revenue
        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-right: 0.0px; border-bottom-width: 2.25pt; text-align: right; padding-left: 0.0px; border-bottom-style: double; border-bottom-color: black; white-space: nowrap">
          $
        </td>
        <td valign="bottom" style="padding-right: 0.0px; border-bottom-width: 2.25pt; text-align: right; padding-left: 0.0px; border-bottom-style: double; border-bottom-color: black; white-space: nowrap">
          27,178
        </td>
        <td style="border-bottom-width: 2.25pt; border-bottom-style: double; border-bottom-color: black">
          &#160;
        </td>
        <td valign="bottom" style="padding-right: 0.0px; border-bottom-width: 2.25pt; text-align: right; padding-left: 0.0px; border-bottom-style: double; border-bottom-color: black; white-space: nowrap">
          100
        </td>
        <td valign="bottom" style="padding-right: 0.0px; border-bottom-width: 2.25pt; text-align: left; padding-left: 0.0px; border-bottom-style: double; border-bottom-color: black; white-space: nowrap">
          %
        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-right: 0.0px; border-bottom-width: 2.25pt; text-align: right; padding-left: 0.0px; border-bottom-style: double; border-bottom-color: black; white-space: nowrap">
          $
        </td>
        <td valign="bottom" style="padding-right: 0.0px; border-bottom-width: 2.25pt; text-align: right; padding-left: 0.0px; border-bottom-style: double; border-bottom-color: black; white-space: nowrap">
          25,783
        </td>
        <td style="border-bottom-width: 2.25pt; border-bottom-style: double; border-bottom-color: black">
          &#160;
        </td>
        <td valign="bottom" style="padding-right: 0.0px; border-bottom-width: 2.25pt; text-align: right; padding-left: 0.0px; border-bottom-style: double; border-bottom-color: black; white-space: nowrap">
          100
        </td>
        <td valign="bottom" style="padding-right: 0.0px; border-bottom-width: 2.25pt; text-align: left; padding-left: 0.0px; border-bottom-style: double; border-bottom-color: black; white-space: nowrap">
          %
        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-right: 0.0px; border-bottom-width: 2.25pt; text-align: right; padding-left: 0.0px; border-bottom-style: double; border-bottom-color: black; white-space: nowrap">
          $
        </td>
        <td valign="bottom" style="padding-right: 0.0px; border-bottom-width: 2.25pt; text-align: right; padding-left: 0.0px; border-bottom-style: double; border-bottom-color: black; white-space: nowrap">
          78,899
        </td>
        <td style="border-bottom-width: 2.25pt; border-bottom-style: double; border-bottom-color: black">
          &#160;
        </td>
        <td valign="bottom" style="padding-right: 0.0px; border-bottom-width: 2.25pt; text-align: right; padding-left: 0.0px; border-bottom-style: double; border-bottom-color: black; white-space: nowrap">
          100
        </td>
        <td valign="bottom" style="padding-right: 0.0px; border-bottom-width: 2.25pt; text-align: left; padding-left: 0.0px; border-bottom-style: double; border-bottom-color: black; white-space: nowrap">
          %
        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-right: 0.0px; border-bottom-width: 2.25pt; text-align: right; padding-left: 0.0px; border-bottom-style: double; border-bottom-color: black; white-space: nowrap">
          $
        </td>
        <td valign="bottom" style="padding-right: 0.0px; border-bottom-width: 2.25pt; text-align: right; padding-left: 0.0px; border-bottom-style: double; border-bottom-color: black; white-space: nowrap">
          74,636
        </td>
        <td style="border-bottom-width: 2.25pt; border-bottom-style: double; border-bottom-color: black">
          &#160;
        </td>
        <td valign="bottom" style="padding-right: 0.0px; border-bottom-width: 2.25pt; text-align: right; padding-left: 0.0px; border-bottom-style: double; border-bottom-color: black; white-space: nowrap">
          100
        </td>
        <td valign="bottom" style="padding-right: 0.0px; border-bottom-width: 2.25pt; text-align: left; padding-left: 0.0px; border-bottom-style: double; border-bottom-color: black; white-space: nowrap">
          %
        </td>
      </tr>
      <tr>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td colspan="3">

        </td>
        <td colspan="2">

        </td>
        <td>

        </td>
        <td>

        </td>
        <td colspan="3">

        </td>
        <td colspan="2">

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td colspan="3">

        </td>
        <td colspan="2">

        </td>
        <td>

        </td>
        <td>

        </td>
        <td colspan="3">

        </td>
        <td colspan="2">
          &#160;
        </td>
      </tr>
      <tr>
        <td valign="top" style="text-align: left; padding-left: 0.0px">
          Product Gross Profit
        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-right: 0.0px; text-align: right; padding-left: 0.0px; white-space: nowrap">
          $
        </td>
        <td valign="bottom" style="padding-right: 0.0px; text-align: right; padding-left: 0.0px; white-space: nowrap">
          20,928
        </td>
        <td>

        </td>
        <td colspan="2">

        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-right: 0.0px; text-align: right; padding-left: 0.0px; white-space: nowrap">
          $
        </td>
        <td valign="bottom" style="padding-right: 0.0px; text-align: right; padding-left: 0.0px; white-space: nowrap">
          20,785
        </td>
        <td>

        </td>
        <td colspan="2">

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-right: 0.0px; text-align: right; padding-left: 0.0px; white-space: nowrap">
          $
        </td>
        <td valign="bottom" style="padding-right: 0.0px; text-align: right; padding-left: 0.0px; white-space: nowrap">
          60,251
        </td>
        <td>

        </td>
        <td colspan="2">

        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-right: 0.0px; text-align: right; padding-left: 0.0px; white-space: nowrap">
          $
        </td>
        <td valign="bottom" style="padding-right: 0.0px; text-align: right; padding-left: 0.0px; white-space: nowrap">
          58,148
        </td>
        <td>

        </td>
        <td colspan="2">

        </td>
      </tr>
      <tr>
        <td valign="top" style="text-align: left; padding-left: 0.0px">
          Product Gross Margin
        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-right: 0.0px; text-align: right; padding-left: 0.0px; white-space: nowrap">
          <p style="margin-bottom: 0px; margin-top: 0px">
            77%
          </p>
        </td>
        <td valign="bottom" style="text-align: left; padding-left: 0.0px">
          <p style="margin-bottom: 0px; margin-top: 0px">
            &#160;
          </p>
        </td>
        <td colspan="2">

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-right: 0.0px; text-align: right; padding-left: 0.0px; white-space: nowrap">
          <p style="margin-bottom: 0px; margin-top: 0px">
            81%
          </p>
        </td>
        <td valign="bottom" style="text-align: left; padding-left: 0.0px">
          <p style="margin-bottom: 0px; margin-top: 0px">
            &#160;
          </p>
        </td>
        <td colspan="2">

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-right: 0.0px; text-align: right; padding-left: 0.0px; white-space: nowrap">
          <p style="margin-bottom: 0px; margin-top: 0px">
            76%
          </p>
        </td>
        <td valign="bottom" style="text-align: left; padding-left: 0.0px">
          <p style="margin-bottom: 0px; margin-top: 0px">
            &#160;
          </p>
        </td>
        <td colspan="2">

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-right: 0.0px; text-align: right; padding-left: 0.0px; white-space: nowrap">
          <p style="margin-bottom: 0px; margin-top: 0px">
            78%
          </p>
        </td>
        <td valign="bottom" style="text-align: left; padding-left: 0.0px">
          <p style="margin-bottom: 0px; margin-top: 0px">
            &#160;
          </p>
        </td>
        <td colspan="2">

        </td>
      </tr>
      <tr>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td colspan="3">

        </td>
        <td colspan="2">

        </td>
        <td>

        </td>
        <td>

        </td>
        <td colspan="3">

        </td>
        <td colspan="2">

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td colspan="3">

        </td>
        <td colspan="2">

        </td>
        <td>

        </td>
        <td>

        </td>
        <td colspan="3">

        </td>
        <td colspan="2">
          &#160;
        </td>
      </tr>
      <tr>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td colspan="3">

        </td>
        <td colspan="2">

        </td>
        <td>

        </td>
        <td>

        </td>
        <td colspan="3">

        </td>
        <td colspan="2">

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td colspan="3">

        </td>
        <td colspan="2">

        </td>
        <td>

        </td>
        <td>

        </td>
        <td colspan="3">

        </td>
        <td colspan="2">
          &#160;
        </td>
      </tr>
      <tr>
        <td colspan="30" valign="top" style="text-align: center; padding-left: 0.0px">
          <b>Product Revenue by Geographic Region</b>
        </td>
      </tr>
      <tr>
        <td colspan="30" valign="top" style="text-align: center; padding-left: 0.0px">
          <b>(in thousands, except percentages)</b>
        </td>
      </tr>
      <tr>
        <td colspan="30" valign="top" style="text-align: center; padding-left: 0.0px">
          (unaudited)
        </td>
      </tr>
      <tr>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td colspan="3">

        </td>
        <td colspan="2">

        </td>
        <td>

        </td>
        <td>

        </td>
        <td colspan="3">

        </td>
        <td colspan="2">

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td colspan="3">

        </td>
        <td colspan="2">

        </td>
        <td>

        </td>
        <td>

        </td>
        <td colspan="3">

        </td>
        <td colspan="2">
          &#160;
        </td>
      </tr>
      <tr>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td colspan="13" valign="top" style="border-bottom-width: 1.0pt; text-align: center; padding-left: 0.0px; border-bottom-style: solid; border-bottom-color: black">
          <b>For the Three Months Ended September 30,</b>
        </td>
        <td>

        </td>
        <td>

        </td>
        <td colspan="12" valign="top" style="border-bottom-width: 1.0pt; text-align: center; padding-left: 0.0px; border-bottom-style: solid; border-bottom-color: black">
          <b>For the Nine Months Ended September 30,</b>
        </td>
      </tr>
      <tr>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td colspan="3" valign="bottom" style="padding-right: 0.0px; border-bottom-width: 1.0pt; text-align: center; padding-left: 0.0px; border-bottom-style: solid; border-bottom-color: black; white-space: nowrap">
          <b>2017</b>
        </td>
        <td colspan="2" valign="bottom" style="padding-right: 0.0px; border-bottom-width: 1.0pt; text-align: center; padding-left: 0.0px; border-bottom-style: solid; border-bottom-color: black; white-space: nowrap">
          <b>%</b>
        </td>
        <td>

        </td>
        <td>

        </td>
        <td colspan="3" valign="bottom" style="padding-right: 0.0px; border-bottom-width: 1.0pt; text-align: center; padding-left: 0.0px; border-bottom-style: solid; border-bottom-color: black; white-space: nowrap">
          <b>2016</b>
        </td>
        <td colspan="2" valign="bottom" style="padding-right: 0.0px; border-bottom-width: 1.0pt; text-align: center; padding-left: 0.0px; border-bottom-style: solid; border-bottom-color: black; white-space: nowrap">
          <b>%</b>
        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td colspan="3" valign="bottom" style="padding-right: 0.0px; border-bottom-width: 1.0pt; text-align: center; padding-left: 0.0px; border-bottom-style: solid; border-bottom-color: black; white-space: nowrap">
          <b>2017</b>
        </td>
        <td colspan="2" valign="bottom" style="padding-right: 0.0px; border-bottom-width: 1.0pt; text-align: center; padding-left: 0.0px; border-bottom-style: solid; border-bottom-color: black; white-space: nowrap">
          <b>%</b>
        </td>
        <td>

        </td>
        <td>

        </td>
        <td colspan="3" valign="bottom" style="padding-right: 0.0px; border-bottom-width: 1.0pt; text-align: center; padding-left: 0.0px; border-bottom-style: solid; border-bottom-color: black; white-space: nowrap">
          <b>2016</b>
        </td>
        <td colspan="2" valign="bottom" style="padding-right: 0.0px; border-bottom-width: 1.0pt; text-align: center; padding-left: 0.0px; border-bottom-style: solid; border-bottom-color: black; white-space: nowrap">
          %
        </td>
      </tr>
      <tr>
        <td valign="top" style="text-align: left; padding-left: 0.0px">
          <b>Geographic Region:</b>
        </td>
        <td>

        </td>
        <td>

        </td>
        <td colspan="3">

        </td>
        <td colspan="2">

        </td>
        <td>

        </td>
        <td>

        </td>
        <td colspan="3">

        </td>
        <td colspan="2">

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td colspan="3">

        </td>
        <td colspan="2">

        </td>
        <td>

        </td>
        <td>

        </td>
        <td colspan="3">

        </td>
        <td colspan="2">

        </td>
      </tr>
      <tr>
        <td valign="top" style="text-align: left; padding-left: 20.0px">
          United States
        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-right: 0.0px; text-align: right; padding-left: 0.0px; white-space: nowrap">
          $
        </td>
        <td valign="bottom" style="padding-right: 0.0px; text-align: right; padding-left: 0.0px; white-space: nowrap">
          22,227
        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-right: 0.0px; text-align: right; padding-left: 0.0px; white-space: nowrap">
          82
        </td>
        <td valign="bottom" style="padding-right: 0.0px; text-align: left; padding-left: 0.0px; white-space: nowrap">
          %
        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-right: 0.0px; text-align: right; padding-left: 0.0px; white-space: nowrap">
          $
        </td>
        <td valign="bottom" style="padding-right: 0.0px; text-align: right; padding-left: 0.0px; white-space: nowrap">
          21,126
        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-right: 0.0px; text-align: right; padding-left: 0.0px; white-space: nowrap">
          82
        </td>
        <td valign="bottom" style="padding-right: 0.0px; text-align: left; padding-left: 0.0px; white-space: nowrap">
          %
        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-right: 0.0px; text-align: right; padding-left: 0.0px; white-space: nowrap">
          $
        </td>
        <td valign="bottom" style="padding-right: 0.0px; text-align: right; padding-left: 0.0px; white-space: nowrap">
          63,507
        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-right: 0.0px; text-align: right; padding-left: 0.0px; white-space: nowrap">
          81
        </td>
        <td valign="bottom" style="padding-right: 0.0px; text-align: left; padding-left: 0.0px; white-space: nowrap">
          %
        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-right: 0.0px; text-align: right; padding-left: 0.0px; white-space: nowrap">
          $
        </td>
        <td valign="bottom" style="padding-right: 0.0px; text-align: right; padding-left: 0.0px; white-space: nowrap">
          61,032
        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-right: 0.0px; text-align: right; padding-left: 0.0px; white-space: nowrap">
          82
        </td>
        <td valign="bottom" style="padding-right: 0.0px; text-align: left; padding-left: 0.0px; white-space: nowrap">
          %
        </td>
      </tr>
      <tr>
        <td valign="top" style="text-align: left; padding-left: 20.0px">
          Europe
        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-right: 0.0px; text-align: right; padding-left: 0.0px; white-space: nowrap">
          2,832
        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-right: 0.0px; text-align: right; padding-left: 0.0px; white-space: nowrap">
          10
        </td>
        <td valign="bottom" style="padding-right: 0.0px; text-align: left; padding-left: 0.0px; white-space: nowrap">
          %
        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-right: 0.0px; text-align: right; padding-left: 0.0px; white-space: nowrap">
          2,703
        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-right: 0.0px; text-align: right; padding-left: 0.0px; white-space: nowrap">
          10
        </td>
        <td valign="bottom" style="padding-right: 0.0px; text-align: left; padding-left: 0.0px; white-space: nowrap">
          %
        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-right: 0.0px; text-align: right; padding-left: 0.0px; white-space: nowrap">
          9,743
        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-right: 0.0px; text-align: right; padding-left: 0.0px; white-space: nowrap">
          12
        </td>
        <td valign="bottom" style="padding-right: 0.0px; text-align: left; padding-left: 0.0px; white-space: nowrap">
          %
        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-right: 0.0px; text-align: right; padding-left: 0.0px; white-space: nowrap">
          8,240
        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-right: 0.0px; text-align: right; padding-left: 0.0px; white-space: nowrap">
          11
        </td>
        <td valign="bottom" style="padding-right: 0.0px; text-align: left; padding-left: 0.0px; white-space: nowrap">
          %
        </td>
      </tr>
      <tr>
        <td valign="top" style="text-align: left; padding-left: 20.0px; padding-bottom: 2.0px">
          Other
        </td>
        <td>

        </td>
        <td>

        </td>
        <td style="border-bottom-width: 1.0pt; border-bottom-style: solid; border-bottom-color: black">
          &#160;
        </td>
        <td valign="bottom" style="padding-right: 0.0px; border-bottom-width: 1.0pt; text-align: right; padding-left: 0.0px; border-bottom-style: solid; border-bottom-color: black; white-space: nowrap">
          2,119
        </td>
        <td style="border-bottom-width: 1.0pt; border-bottom-style: solid; border-bottom-color: black">
          &#160;
        </td>
        <td valign="bottom" style="padding-right: 0.0px; border-bottom-width: 1.0pt; text-align: right; padding-left: 0.0px; border-bottom-style: solid; border-bottom-color: black; white-space: nowrap">
          8
        </td>
        <td valign="bottom" style="padding-right: 0.0px; border-bottom-width: 1.0pt; text-align: left; padding-left: 0.0px; border-bottom-style: solid; border-bottom-color: black; white-space: nowrap">
          %
        </td>
        <td>

        </td>
        <td>

        </td>
        <td style="border-bottom-width: 1.0pt; border-bottom-style: solid; border-bottom-color: black">
          &#160;
        </td>
        <td valign="bottom" style="padding-right: 0.0px; border-bottom-width: 1.0pt; text-align: right; padding-left: 0.0px; border-bottom-style: solid; border-bottom-color: black; white-space: nowrap">
          1,954
        </td>
        <td style="border-bottom-width: 1.0pt; border-bottom-style: solid; border-bottom-color: black">
          &#160;
        </td>
        <td valign="bottom" style="padding-right: 0.0px; border-bottom-width: 1.0pt; text-align: right; padding-left: 0.0px; border-bottom-style: solid; border-bottom-color: black; white-space: nowrap">
          8
        </td>
        <td valign="bottom" style="padding-right: 0.0px; border-bottom-width: 1.0pt; text-align: left; padding-left: 0.0px; border-bottom-style: solid; border-bottom-color: black; white-space: nowrap">
          %
        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td style="border-bottom-width: 1.0pt; border-bottom-style: solid; border-bottom-color: black">
          &#160;
        </td>
        <td valign="bottom" style="padding-right: 0.0px; border-bottom-width: 1.0pt; text-align: right; padding-left: 0.0px; border-bottom-style: solid; border-bottom-color: black; white-space: nowrap">
          5,649
        </td>
        <td style="border-bottom-width: 1.0pt; border-bottom-style: solid; border-bottom-color: black">
          &#160;
        </td>
        <td valign="bottom" style="padding-right: 0.0px; border-bottom-width: 1.0pt; text-align: right; padding-left: 0.0px; border-bottom-style: solid; border-bottom-color: black; white-space: nowrap">
          7
        </td>
        <td valign="bottom" style="padding-right: 0.0px; border-bottom-width: 1.0pt; text-align: left; padding-left: 0.0px; border-bottom-style: solid; border-bottom-color: black; white-space: nowrap">
          %
        </td>
        <td>

        </td>
        <td>

        </td>
        <td style="border-bottom-width: 1.0pt; border-bottom-style: solid; border-bottom-color: black">
          &#160;
        </td>
        <td valign="bottom" style="padding-right: 0.0px; border-bottom-width: 1.0pt; text-align: right; padding-left: 0.0px; border-bottom-style: solid; border-bottom-color: black; white-space: nowrap">
          5,364
        </td>
        <td style="border-bottom-width: 1.0pt; border-bottom-style: solid; border-bottom-color: black">
          &#160;
        </td>
        <td valign="bottom" style="padding-right: 0.0px; border-bottom-width: 1.0pt; text-align: right; padding-left: 0.0px; border-bottom-style: solid; border-bottom-color: black; white-space: nowrap">
          7
        </td>
        <td valign="bottom" style="padding-right: 0.0px; border-bottom-width: 1.0pt; text-align: left; padding-left: 0.0px; border-bottom-style: solid; border-bottom-color: black; white-space: nowrap">
          %
        </td>
      </tr>
      <tr>
        <td valign="top" style="text-align: left; padding-left: 20.0px; padding-bottom: 4.0px">
          Product Revenue
        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-right: 0.0px; border-bottom-width: 2.25pt; text-align: right; padding-left: 0.0px; border-bottom-style: double; border-bottom-color: black; white-space: nowrap">
          $
        </td>
        <td valign="bottom" style="padding-right: 0.0px; border-bottom-width: 2.25pt; text-align: right; padding-left: 0.0px; border-bottom-style: double; border-bottom-color: black; white-space: nowrap">
          27,178
        </td>
        <td style="border-bottom-width: 2.25pt; border-bottom-style: double; border-bottom-color: black">
          &#160;
        </td>
        <td valign="bottom" style="padding-right: 0.0px; border-bottom-width: 2.25pt; text-align: right; padding-left: 0.0px; border-bottom-style: double; border-bottom-color: black; white-space: nowrap">
          100
        </td>
        <td valign="bottom" style="padding-right: 0.0px; border-bottom-width: 2.25pt; text-align: left; padding-left: 0.0px; border-bottom-style: double; border-bottom-color: black; white-space: nowrap">
          %
        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-right: 0.0px; border-bottom-width: 2.25pt; text-align: right; padding-left: 0.0px; border-bottom-style: double; border-bottom-color: black; white-space: nowrap">
          $
        </td>
        <td valign="bottom" style="padding-right: 0.0px; border-bottom-width: 2.25pt; text-align: right; padding-left: 0.0px; border-bottom-style: double; border-bottom-color: black; white-space: nowrap">
          25,783
        </td>
        <td style="border-bottom-width: 2.25pt; border-bottom-style: double; border-bottom-color: black">
          &#160;
        </td>
        <td valign="bottom" style="padding-right: 0.0px; border-bottom-width: 2.25pt; text-align: right; padding-left: 0.0px; border-bottom-style: double; border-bottom-color: black; white-space: nowrap">
          100
        </td>
        <td valign="bottom" style="padding-right: 0.0px; border-bottom-width: 2.25pt; text-align: left; padding-left: 0.0px; border-bottom-style: double; border-bottom-color: black; white-space: nowrap">
          %
        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-right: 0.0px; border-bottom-width: 2.25pt; text-align: right; padding-left: 0.0px; border-bottom-style: double; border-bottom-color: black; white-space: nowrap">
          $
        </td>
        <td valign="bottom" style="padding-right: 0.0px; border-bottom-width: 2.25pt; text-align: right; padding-left: 0.0px; border-bottom-style: double; border-bottom-color: black; white-space: nowrap">
          78,899
        </td>
        <td style="border-bottom-width: 2.25pt; border-bottom-style: double; border-bottom-color: black">
          &#160;
        </td>
        <td valign="bottom" style="padding-right: 0.0px; border-bottom-width: 2.25pt; text-align: right; padding-left: 0.0px; border-bottom-style: double; border-bottom-color: black; white-space: nowrap">
          100
        </td>
        <td valign="bottom" style="padding-right: 0.0px; border-bottom-width: 2.25pt; text-align: left; padding-left: 0.0px; border-bottom-style: double; border-bottom-color: black; white-space: nowrap">
          %
        </td>
        <td>

        </td>
        <td>

        </td>
        <td valign="bottom" style="padding-right: 0.0px; border-bottom-width: 2.25pt; text-align: right; padding-left: 0.0px; border-bottom-style: double; border-bottom-color: black; white-space: nowrap">
          $
        </td>
        <td valign="bottom" style="padding-right: 0.0px; border-bottom-width: 2.25pt; text-align: right; padding-left: 0.0px; border-bottom-style: double; border-bottom-color: black; white-space: nowrap">
          74,636
        </td>
        <td style="border-bottom-width: 2.25pt; border-bottom-style: double; border-bottom-color: black">
          &#160;
        </td>
        <td valign="bottom" style="padding-right: 0.0px; border-bottom-width: 2.25pt; text-align: right; padding-left: 0.0px; border-bottom-style: double; border-bottom-color: black; white-space: nowrap">
          100
        </td>
        <td valign="bottom" style="padding-right: 0.0px; border-bottom-width: 2.25pt; text-align: left; padding-left: 0.0px; border-bottom-style: double; border-bottom-color: black; white-space: nowrap">
          %
        </td>
      </tr>
      <tr>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>

        </td>
        <td>
          &#160;
        </td>
      </tr>
    </table>
    </div>
    <p>

    </p>
    <p>
      CONTACT:<br>Anika Therapeutics, Inc.<br>Charles H. Sherwood, Ph.D., CEO<br>Sylvia
      Cheung, CFO<br>Tel: 781-457-9000
    </p>
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</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
