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Note 11 - Accrued Expenses (Tables)
 9 Months Ended
Sep. 30, 2018
Notes Tables  
Schedule of Accrued Liabilities [Table Text Block]
    September 30,
2018		     December 31,
2017		  
Compensation and related expenses   $
3,875
     $
2,893
  
Clinical trial costs    
586
      
2,318
  
Accrued liabilities related to product recall    
344
      
-
  
Research grants    
406
      
419
  
Professional fees    
1,233
      
448
  
Deferred revenue    
52
      
-
  
Other    
347
      
248
  
Total   $
6,843
     $
6,326