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Note 13 - Revenue and Geographic Information (Tables) | 12 Months Ended
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Dec. 31, 2021
Notes Tables |
Revenue from External Customers by Products and Services [Table Text Block] |
|  | Years Ended December 31, |
|  | 2021 |  |  | 2020 |  |  | 2019 |
Product revenue |  | $ | 147,794 |  |  | $ | 130,457 |  |  | $ | 114,512 |
Licensing, milestone and contract revenue |  |  | - |  |  |  | - |  |  |  | 98 |
Total revenue |  | $ | 147,794 |  |  | $ | 130,457 |  |  | $ | 114,610 |
|  | Years Ended December 31, |
|  | 2021 |  |  | 2020 |  |  | 2019 |
|  | Revenue |  |  | Percentage of Product Revenue |  |  | Revenue |  |  | Percentage of Product Revenue |  |  | Revenue |  |  | Percentage of Product Revenue |
OA Pain Management |  | $ | 89,503 |  |  |  | 61 | % |  | $ | 83,029 |  |  |  | 64 | % |  | $ | 103,466 |  |  |  | 90 | %
Joint Preservation and Restoration |  |  | 48,588 |  |  |  | 33 | % |  |  | 39,368 |  |  |  | 30 | % |  |  | 2,070 |  |  |  | 2 | %
Non-Orthopedic |  |  | 9,703 |  |  |  | 6 | % |  |  | 8,060 |  |  |  | 6 | % |  |  | 8,976 |  |  |  | 8 | %
Total |  | $ | 147,794 |  |  |  | 100 | % |  | $ | 130,457 |  |  |  | 100 | % |  | $ | 114,512 |  |  |  | 100 | %
Schedule of Revenue and Operating Income by Geographical Areas [Table Text Block] |
|  | Years Ended December 31, |
|  | 2021 |  |  | 2020 |  |  | 2019 |
|  | Total |  |  | Percentage of |  |  | Total |  |  | Percentage of |  |  | Total |  |  | Percentage of |
|  | Revenue |  |  | Revenue |  |  | Revenue |  |  | Revenue |  |  | Revenue |  |  | Revenue |
Geographic Location: |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
United States |  | $ | 113,833 |  |  |  | 77 | % |  | $ | 103,182 |  |  |  | 79 | % |  | $ | 90,302 |  |  |  | 79 | %
Europe |  |  | 19,580 |  |  |  | 13 | % |  |  | 14,179 |  |  |  | 11 | % |  |  | 14,744 |  |  |  | 13 | %
Other |  |  | 14,381 |  |  |  | 10 | % |  |  | 13,096 |  |  |  | 10 | % |  |  | 9,564 |  |  |  | 8 | %
Total |  | $ | 147,794 |  |  |  | 100 | % |  | $ | 130,457 |  |  |  | 100 | % |  | $ | 114,610 |  |  |  | 100 | %
Schedule of Revenue from External Customers and Long-Lived Assets, by Geographical Areas [Table Text Block] |
|  | Years Ended December 31, |
|  | 2021 |  |  | 2020 |
United States |  | $ | 46,068 |  |  | $ | 48,611 |
Italy |  |  | 1,534 |  |  |  | 2,002 |
Total |  | $ | 47,602 |  |  | $ | 50,613 |

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