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Net Loss per Share (Details)
 6 Months Ended
Jun. 30, 2012
Jun. 30, 2011
Summary of common shares that were excluded from the diluted net loss per share calculation because of their anti-dilutive effect    
Total 38,205,939 32,741,278
Options to purchase common stock [Member]
    
Summary of common shares that were excluded from the diluted net loss per share calculation because of their anti-dilutive effect    
Total 16,423,862 14,369,591
Warrants to purchase common stock [Member]
    
Summary of common shares that were excluded from the diluted net loss per share calculation because of their anti-dilutive effect    
Total 21,743,844 18,333,454
Convertible preferred stock [Member]
    
Summary of common shares that were excluded from the diluted net loss per share calculation because of their anti-dilutive effect    
Total 38,233 38,233