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Net Loss per Share (Details)
 9 Months Ended
Sep. 30, 2012
Sep. 30, 2011
Summary of common shares that were excluded from the diluted net loss per share calculation because of their anti-dilutive effect    
Total 38,171,062 32,791,278
Options to purchase common stock [Member]
    
Summary of common shares that were excluded from the diluted net loss per share calculation because of their anti-dilutive effect    
Total 16,538,985 14,419,591
Warrants to purchase common stock [Member]
    
Summary of common shares that were excluded from the diluted net loss per share calculation because of their anti-dilutive effect    
Total 21,593,844 18,333,454
Convertible preferred stock [Member]
    
Summary of common shares that were excluded from the diluted net loss per share calculation because of their anti-dilutive effect    
Total 38,233 38,233