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Income Taxes (Details 2) (USD $) | Dec. 31, 2012 | Dec. 31, 2011
--- | --- | ---
Deferred tax assets: |  |
Capitalized research expense | $ 3,191,000 | $ 4,089,000
Net operating loss carry forwards | 43,233,000 | 34,899,000
Research and development and other tax credits | 1,134,000 | 1,073,000
Other | 6,569,000 | 6,557,000
Deferred Tax Assets, Gross | 54,127,000 | 46,618,000
Valuation allowance | (52,185,000) | (44,784,000)
Total deferred tax assets | 1,942,000 | 1,834,000
Deferred tax liabilities: |  |
Acquired intangibles | (1,532,000) | (2,094,000)
Investment in affiliated entity | (511,000) | 181,000
Net deferred tax liabilities | $ (101,000) | $ (79,000)

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