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Net loss per share (Tables)
3 Months Ended
Mar. 31, 2013
Earnings Per Share [Abstract]  
Schedule of Antidilutive Securities Excluded from Computation of Earnings Per Share
The following table summarizes potential common shares that were excluded from the diluted net loss per share calculation because of their anti-dilutive effect:
 
As of March 31,
Common Stock Equivalents
2013
 
2012
Options to purchase common stock
18,493,523

 
16,495,527

Warrants to purchase common stock
35,227,529

 
21,743,844

Convertible preferred stock
38,233

 
38,233

Total
53,759,285

 
38,277,604