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Consolidated Statements of Cash Flows (Unaudited) (USD $) | 12 Months Ended
--- | ---
Dec. 31, 2013 | Dec. 31, 2012 | Dec. 31, 2011
Cash flows from operating activities: |  |  |
Net loss | $ (66,083,532) | $ (19,712,980) | $ (15,304,095)
Adjustments to reconcile net loss to net cash used in operating activities: |  |  |
Depreciation | 328,752 | 173,750 | 142,197
Amortization of intangible assets | 1,770,537 | 1,821,170 | 1,869,517
Change in value of common stock warrants | 45,632,669 | (1,982,620) | (8,690,658)
Stock-based compensation | 1,868,345 | 1,345,613 | 1,654,823
Interest income accrued on short-term investments | (484) | (1,147) | 6,271
Deferred taxes | 32,274 | 22,806 | 25,673
Deferred rent | 410,187 | (15,799) | 13,763
Transaction costs associated with issuance of warrants | 315,970 | 0 | 0
Loss on short-term investments | 38,950 | 0 | 0
Loss on disposal of fixed assets | 1,822 | 0 | 0
Loss (Gain) on investment in affiliated entity | 1,038,745 | (1,631,819) | 2,390,498
Gain on sale of intangible assets | (2,000,000) | (1,151,000) | (587,000)
Changes in operating assets and liabilities: |  |  |
Accounts receivable | (2,471,130) | (362,524) | (435,022)
Accounts receivable from affiliated entity | 36,234 | 2,172 | 33,743
Prepaid expenses and other current assets | (229,705) | 363,584 | (472,074)
Prepaid expenses and other current assets from affiliated entity | (1,401,258) | (445,981) | 212,250
Restricted cash | (352) | (351) | (100,059)
Other assets | 26,793 | (14,794) | 50,866
Accounts payable and accrued expenses | 2,164,045 | (790,844) | 1,789,376
Accounts payable and accrued expenses due to affiliated entity | 334,980 | 166,931 | (1,660,603)
Deferred revenue | 3,179,721 | 282,048 | (333,725)
Deferred revenue from affiliated entity | (375,000) | (375,000) | (361,458)
Net cash used in operating activities | (15,381,437) | (22,306,785) | (19,755,717)
Cash flows from investing activities: |  |  |
Purchases of investments | (15,399,495) | (9,142,220) | (18,193,614)
Maturities of investments | 4,339,577 | 14,008,771 | 7,206,000
Purchases of capital assets | (176,925) | (240,986) | (161,187)
Additional investment in affiliated entity | 0 | 0 | (101,123)
Proceeds from sale of intangible assets | 2,000,000 | 650,000 | 350,000
Net cash (used in) provided by investing activities | (9,236,843) | 5,275,565 | (10,899,924)
Cash flows from financing activities: |  |  |
Proceeds from issuance of common stock and warrants, net of issuance costs | 32,883,705 | 5,325,141 | 27,994,601
Proceeds from stock option and warrant exercises | 19,808,232 | 0 | 15,930
Net cash provided by financing activities | 52,691,937 | 5,325,141 | 28,010,531
Effect of exchange rate changes on cash and cash equivalents | 118 | 1,984 | (3,263)
Increase (Decrease) in cash and cash equivalents | 28,073,775 | (11,704,095) | (2,648,373)
Cash and cash equivalents, beginning of period | 5,646,021 | 17,350,116 | 19,998,489
Cash and cash equivalents, end of period | 33,719,796 | 5,646,021 | 17,350,116
Supplemental disclosure of non-cash activities |  |  |
Lease incentive | $ 2,538,000 | $ 0 | $ 0

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- Definition The cash outflow for securities or other assets acquired, which qualify for treatment as an investing activity and are to be liquidated, if necessary, within the current operating cycle. Includes cash flows from securities classified as trading securities that were acquired for reasons other than sale in the short-term. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Glossary Investing Activities -URI http://asc.fasb.org/extlink&oid=6516133 Reference 2: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 230 -SubTopic 10 -Section 45 -Paragraph 13 -URI http://asc.fasb.org/extlink&oid=31042434&loc=d3e3213-108585 + Details
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- Definition The cash inflow from the additional capital contribution to the entity. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Glossary Financing Activities -URI http://asc.fasb.org/extlink&oid=6513228 Reference 2: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 230 -SubTopic 10 -Section 45 -Paragraph 14 -Subparagraph (a) -URI http://asc.fasb.org/extlink&oid=31042434&loc=d3e3255-108585 + Details
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- Definition The cash inflow from disposal of asset without physical form usually arising from contractual or other legal rights, excluding goodwill. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Glossary Investing Activities -URI http://asc.fasb.org/extlink&oid=6516133 Reference 2: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 230 -SubTopic 10 -Section 45 -Paragraph 12 -Subparagraph (c) -URI http://asc.fasb.org/extlink&oid=31042434&loc=d3e3179-108585 + Details
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- Definition The cash inflow from sales of all investments, including securities and other assets, having ready marketability and intended by management to be liquidated, if necessary, within the current operating cycle. Includes cash flows from securities classified as trading securities that were acquired for reasons other than sale in the short-term. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 230 -SubTopic 10 -Section 45 -Paragraph 12 -URI http://asc.fasb.org/extlink&oid=31042434&loc=d3e3179-108585 Reference 2: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Glossary Investing Activities -URI http://asc.fasb.org/extlink&oid=6516133 + Details
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- Definition The consolidated profit or loss for the period, net of income taxes, including the portion attributable to the noncontrolling interest. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 810 -SubTopic 10 -Section 55 -Paragraph 4K -URI http://asc.fasb.org/extlink&oid=31814832&loc=SL4591552-111686 Reference 2: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 810 -SubTopic 10 -Section 45 -Paragraph 19 -URI http://asc.fasb.org/extlink&oid=7656940&loc=SL4569616-111683 Reference 3: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 810 -SubTopic 10 -Section 50 -Paragraph 1A -Subparagraph (a),(c) -URI http://asc.fasb.org/extlink&oid=18733093&loc=SL4573702-111684 Reference 4: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 810 -SubTopic 10 -Section 55 -Paragraph 4J -URI http://asc.fasb.org/extlink&oid=31814832&loc=SL4591551-111686 + Details
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- Definition The aggregate amount of noncash, equity-based employee remuneration. This may include the value of stock or unit options, amortization of restricted stock or units, and adjustment for officers' compensation. As noncash, this element is an add back when calculating net cash generated by operating activities using the indirect method. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 230 -SubTopic 10 -Section 45 -Paragraph 28 -Subparagraph (a) -URI http://asc.fasb.org/extlink&oid=31042434&loc=d3e3602-108585 + Details
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- Definition Difference between actual rental income due and rental income recognized on a straight-line basis. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 230 -SubTopic 10 -Section 45 -Paragraph 28 -Subparagraph (a) -URI http://asc.fasb.org/extlink&oid=31042434&loc=d3e3602-108585 + Details
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