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Summary of Significant Accounting Policies - Net Loss per Share (Details)	12 Months Ended
	Dec. 31, 2013	Dec. 31, 2012	Dec. 31, 2011
Summary of common shares that were excluded from the diluted net loss per share calculation because of their anti-dilutive effect
Total	30,635,611	37,889,521	36,084,880
Options to purchase common stock [Member]
Summary of common shares that were excluded from the diluted net loss per share calculation because of their anti-dilutive effect
Total	16,538,118	16,257,444	14,302,803
Warrants to purchase common stock [Member]
Summary of common shares that were excluded from the diluted net loss per share calculation because of their anti-dilutive effect
Total	14,059,260	21,593,844	21,743,844
Convertible preferred stock [Member]
Summary of common shares that were excluded from the diluted net loss per share calculation because of their anti-dilutive effect
Total	38,233	38,233	38,233

Securities (including those issuable pursuant to contingent stock agreements) that could potentially dilute basic earnings per share (EPS) or earnings per unit (EPU) in the future that were not included in the computation of diluted EPS or EPU because to do so would increase EPS or EPU amounts or decrease loss per share or unit amounts for the period presented.

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