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Consolidated Statements of Operations (USD $)
 3 Months Ended 12 Months Ended
Dec. 31, 2014
Sep. 30, 2014
Jun. 30, 2014
Mar. 31, 2014
Dec. 31, 2013
Sep. 30, 2013
Jun. 30, 2013
Mar. 31, 2013
Dec. 31, 2014
Dec. 31, 2013
Dec. 31, 2012
Revenues:                      
Revenue under collaborative research and development arrangements $ 1,758,108ino_RevenueUnderCollaborativeResearchandDevelopmentArrangements $ 1,114,952ino_RevenueUnderCollaborativeResearchandDevelopmentArrangements $ 3,107,781ino_RevenueUnderCollaborativeResearchandDevelopmentArrangements $ 1,435,727ino_RevenueUnderCollaborativeResearchandDevelopmentArrangements $ 822,217ino_RevenueUnderCollaborativeResearchandDevelopmentArrangements $ 8,388,760ino_RevenueUnderCollaborativeResearchandDevelopmentArrangements $ 14,311ino_RevenueUnderCollaborativeResearchandDevelopmentArrangements $ 14,259ino_RevenueUnderCollaborativeResearchandDevelopmentArrangements $ 7,416,568ino_RevenueUnderCollaborativeResearchandDevelopmentArrangements $ 9,239,547ino_RevenueUnderCollaborativeResearchandDevelopmentArrangements $ 82,536ino_RevenueUnderCollaborativeResearchandDevelopmentArrangements
Revenue under collaborative research and development arrangements with affiliated entity 112,500ino_RevenueUnderCollaborativeResearchAndDevelopmentArrangementsWithAffiliatedEntity 112,500ino_RevenueUnderCollaborativeResearchAndDevelopmentArrangementsWithAffiliatedEntity 137,500ino_RevenueUnderCollaborativeResearchAndDevelopmentArrangementsWithAffiliatedEntity 116,964ino_RevenueUnderCollaborativeResearchAndDevelopmentArrangementsWithAffiliatedEntity 106,250ino_RevenueUnderCollaborativeResearchAndDevelopmentArrangementsWithAffiliatedEntity 106,250ino_RevenueUnderCollaborativeResearchAndDevelopmentArrangementsWithAffiliatedEntity 106,250ino_RevenueUnderCollaborativeResearchAndDevelopmentArrangementsWithAffiliatedEntity 106,250ino_RevenueUnderCollaborativeResearchAndDevelopmentArrangementsWithAffiliatedEntity 479,464ino_RevenueUnderCollaborativeResearchAndDevelopmentArrangementsWithAffiliatedEntity 425,000ino_RevenueUnderCollaborativeResearchAndDevelopmentArrangementsWithAffiliatedEntity 577,467ino_RevenueUnderCollaborativeResearchAndDevelopmentArrangementsWithAffiliatedEntity
Grants and miscellaneous revenue 586,500us-gaap_RevenueFromGrants 612,901us-gaap_RevenueFromGrants 556,381us-gaap_RevenueFromGrants 804,952us-gaap_RevenueFromGrants 811,199us-gaap_RevenueFromGrants 991,835us-gaap_RevenueFromGrants 665,049us-gaap_RevenueFromGrants 1,334,716us-gaap_RevenueFromGrants 2,560,734us-gaap_RevenueFromGrants 3,802,799us-gaap_RevenueFromGrants 3,458,649us-gaap_RevenueFromGrants
Total revenues 2,457,108us-gaap_Revenues 1,840,353us-gaap_Revenues 3,801,662us-gaap_Revenues 2,357,643us-gaap_Revenues 1,739,666us-gaap_Revenues 9,486,845us-gaap_Revenues 785,610us-gaap_Revenues 1,455,225us-gaap_Revenues 10,456,766us-gaap_Revenues 13,467,346us-gaap_Revenues 4,118,652us-gaap_Revenues
Operating expenses:                      
Research and development 9,244,473us-gaap_ResearchAndDevelopmentExpense 7,017,805us-gaap_ResearchAndDevelopmentExpense 9,607,281us-gaap_ResearchAndDevelopmentExpense 8,225,480us-gaap_ResearchAndDevelopmentExpense 6,404,005us-gaap_ResearchAndDevelopmentExpense 5,438,405us-gaap_ResearchAndDevelopmentExpense 4,411,082us-gaap_ResearchAndDevelopmentExpense 5,115,112us-gaap_ResearchAndDevelopmentExpense 34,095,039us-gaap_ResearchAndDevelopmentExpense 21,368,604us-gaap_ResearchAndDevelopmentExpense 17,984,825us-gaap_ResearchAndDevelopmentExpense
General and administrative 4,224,429us-gaap_GeneralAndAdministrativeExpense 3,153,714us-gaap_GeneralAndAdministrativeExpense 4,347,327us-gaap_GeneralAndAdministrativeExpense 4,132,218us-gaap_GeneralAndAdministrativeExpense 4,339,539us-gaap_GeneralAndAdministrativeExpense 3,282,796us-gaap_GeneralAndAdministrativeExpense 3,046,586us-gaap_GeneralAndAdministrativeExpense 2,974,153us-gaap_GeneralAndAdministrativeExpense 15,857,688us-gaap_GeneralAndAdministrativeExpense 13,643,074us-gaap_GeneralAndAdministrativeExpense 10,778,359us-gaap_GeneralAndAdministrativeExpense
Gain on sale of intangible assets         (1,000,000)us-gaap_GainLossOnDispositionOfIntangibleAssets 0us-gaap_GainLossOnDispositionOfIntangibleAssets (1,000,000)us-gaap_GainLossOnDispositionOfIntangibleAssets 0us-gaap_GainLossOnDispositionOfIntangibleAssets 0us-gaap_GainLossOnDispositionOfIntangibleAssets (2,000,000)us-gaap_GainLossOnDispositionOfIntangibleAssets (1,151,000)us-gaap_GainLossOnDispositionOfIntangibleAssets
Total operating expenses 13,468,902us-gaap_OperatingExpenses 10,171,519us-gaap_OperatingExpenses 13,954,608us-gaap_OperatingExpenses 12,357,698us-gaap_OperatingExpenses 9,743,544us-gaap_OperatingExpenses 8,721,201us-gaap_OperatingExpenses 6,457,668us-gaap_OperatingExpenses 8,089,265us-gaap_OperatingExpenses 49,952,727us-gaap_OperatingExpenses 33,011,678us-gaap_OperatingExpenses 27,612,184us-gaap_OperatingExpenses
Loss from operations (11,011,794)us-gaap_OperatingIncomeLoss (8,331,166)us-gaap_OperatingIncomeLoss (10,152,946)us-gaap_OperatingIncomeLoss (10,000,055)us-gaap_OperatingIncomeLoss (8,003,878)us-gaap_OperatingIncomeLoss 765,644us-gaap_OperatingIncomeLoss (5,672,058)us-gaap_OperatingIncomeLoss (6,634,040)us-gaap_OperatingIncomeLoss (39,495,961)us-gaap_OperatingIncomeLoss (19,544,332)us-gaap_OperatingIncomeLoss (23,493,532)us-gaap_OperatingIncomeLoss
Other income (expense):                      
Interest and other income, net 113,212us-gaap_InterestAndOtherIncome 97,174us-gaap_InterestAndOtherIncome 68,999us-gaap_InterestAndOtherIncome 52,076us-gaap_InterestAndOtherIncome 8,576us-gaap_InterestAndOtherIncome 46,787us-gaap_InterestAndOtherIncome 37,391us-gaap_InterestAndOtherIncome 39,460us-gaap_InterestAndOtherIncome 331,461us-gaap_InterestAndOtherIncome 132,214us-gaap_InterestAndOtherIncome 166,113us-gaap_InterestAndOtherIncome
Change in fair value of common stock warrants 143,659ino_ChangeInFairValueOfCommonStockWarrants (113,980)ino_ChangeInFairValueOfCommonStockWarrants 824,390ino_ChangeInFairValueOfCommonStockWarrants (505,926)ino_ChangeInFairValueOfCommonStockWarrants (6,052,965)ino_ChangeInFairValueOfCommonStockWarrants (34,952,210)ino_ChangeInFairValueOfCommonStockWarrants (3,199,878)ino_ChangeInFairValueOfCommonStockWarrants (1,427,616)ino_ChangeInFairValueOfCommonStockWarrants 348,143ino_ChangeInFairValueOfCommonStockWarrants (45,632,669)ino_ChangeInFairValueOfCommonStockWarrants 1,982,620ino_ChangeInFairValueOfCommonStockWarrants
Gain (Loss) on investment in affiliated entity 3,342,436ino_ChangeInValueOfInvestmentsInAffiliatedCompany 1,168,911ino_ChangeInValueOfInvestmentsInAffiliatedCompany (1,458,160)ino_ChangeInValueOfInvestmentsInAffiliatedCompany (376,963)ino_ChangeInValueOfInvestmentsInAffiliatedCompany (1,419,536)ino_ChangeInValueOfInvestmentsInAffiliatedCompany 3,248,926ino_ChangeInValueOfInvestmentsInAffiliatedCompany (2,032,051)ino_ChangeInValueOfInvestmentsInAffiliatedCompany (836,084)ino_ChangeInValueOfInvestmentsInAffiliatedCompany 2,676,224ino_ChangeInValueOfInvestmentsInAffiliatedCompany (1,038,745)ino_ChangeInValueOfInvestmentsInAffiliatedCompany 1,631,819ino_ChangeInValueOfInvestmentsInAffiliatedCompany
Net loss (7,412,487)us-gaap_ProfitLoss (7,179,061)us-gaap_ProfitLoss (10,717,717)us-gaap_ProfitLoss (10,830,868)us-gaap_ProfitLoss (15,467,803)us-gaap_ProfitLoss (30,890,853)us-gaap_ProfitLoss (10,866,596)us-gaap_ProfitLoss (8,858,280)us-gaap_ProfitLoss (36,140,133)us-gaap_ProfitLoss (66,083,532)us-gaap_ProfitLoss (19,712,980)us-gaap_ProfitLoss
Net loss attributable to non-controlling interest 1,083us-gaap_NetIncomeLossAttributableToNoncontrollingInterest 1,486us-gaap_NetIncomeLossAttributableToNoncontrollingInterest 6,443us-gaap_NetIncomeLossAttributableToNoncontrollingInterest 9,408us-gaap_NetIncomeLossAttributableToNoncontrollingInterest 13,473us-gaap_NetIncomeLossAttributableToNoncontrollingInterest 13,443us-gaap_NetIncomeLossAttributableToNoncontrollingInterest 14,008us-gaap_NetIncomeLossAttributableToNoncontrollingInterest 14,160us-gaap_NetIncomeLossAttributableToNoncontrollingInterest 18,420us-gaap_NetIncomeLossAttributableToNoncontrollingInterest 55,084us-gaap_NetIncomeLossAttributableToNoncontrollingInterest 44,025us-gaap_NetIncomeLossAttributableToNoncontrollingInterest
Net loss attributable to Inovio Pharmaceuticals, Inc. $ (7,411,404)us-gaap_NetIncomeLoss $ (7,177,575)us-gaap_NetIncomeLoss $ (10,711,274)us-gaap_NetIncomeLoss $ (10,821,460)us-gaap_NetIncomeLoss $ (15,454,330)us-gaap_NetIncomeLoss $ (30,877,410)us-gaap_NetIncomeLoss $ (10,852,588)us-gaap_NetIncomeLoss $ (8,844,120)us-gaap_NetIncomeLoss $ (36,121,713)us-gaap_NetIncomeLoss $ (66,028,448)us-gaap_NetIncomeLoss $ (19,668,955)us-gaap_NetIncomeLoss
Net loss per common share attributable to Inovio Pharmaceuticals, Inc. stockholders                      
Basic ($ per share) $ (0.12)us-gaap_EarningsPerShareBasic $ (0.12)us-gaap_EarningsPerShareBasic $ (0.18)us-gaap_EarningsPerShareBasic $ (0.20)us-gaap_EarningsPerShareBasic $ (0.30)us-gaap_EarningsPerShareBasic $ (0.64)us-gaap_EarningsPerShareBasic $ (0.24)us-gaap_EarningsPerShareBasic $ (0.23)us-gaap_EarningsPerShareBasic $ (0.61)us-gaap_EarningsPerShareBasic $ (1.43)us-gaap_EarningsPerShareBasic $ (0.58)us-gaap_EarningsPerShareBasic
Diluted ($ per share) $ (0.12)us-gaap_EarningsPerShareDiluted $ (0.12)us-gaap_EarningsPerShareDiluted $ (0.19)us-gaap_EarningsPerShareDiluted $ (0.20)us-gaap_EarningsPerShareDiluted $ (0.30)us-gaap_EarningsPerShareDiluted $ (0.64)us-gaap_EarningsPerShareDiluted $ (0.24)us-gaap_EarningsPerShareDiluted $ (0.23)us-gaap_EarningsPerShareDiluted $ (0.64)us-gaap_EarningsPerShareDiluted $ (1.43)us-gaap_EarningsPerShareDiluted $ (0.58)us-gaap_EarningsPerShareDiluted
Weighted average number of common shares outstanding used in per share calculations:                      
Basic (in shares) 60,610,367us-gaap_WeightedAverageNumberOfSharesOutstandingBasic 60,392,911us-gaap_WeightedAverageNumberOfSharesOutstandingBasic 60,232,498us-gaap_WeightedAverageNumberOfSharesOutstandingBasic 55,159,002us-gaap_WeightedAverageNumberOfSharesOutstandingBasic 52,127,419us-gaap_WeightedAverageNumberOfSharesOutstandingBasic 47,989,039us-gaap_WeightedAverageNumberOfSharesOutstandingBasic 44,988,704us-gaap_WeightedAverageNumberOfSharesOutstandingBasic 39,038,883us-gaap_WeightedAverageNumberOfSharesOutstandingBasic 59,127,349us-gaap_WeightedAverageNumberOfSharesOutstandingBasic 46,087,773us-gaap_WeightedAverageNumberOfSharesOutstandingBasic 34,127,312us-gaap_WeightedAverageNumberOfSharesOutstandingBasic
Diluted (in shares) 60,805,871us-gaap_WeightedAverageNumberOfDilutedSharesOutstanding 60,602,831us-gaap_WeightedAverageNumberOfDilutedSharesOutstanding 60,474,859us-gaap_WeightedAverageNumberOfDilutedSharesOutstanding 55,159,002us-gaap_WeightedAverageNumberOfDilutedSharesOutstanding 52,127,419us-gaap_WeightedAverageNumberOfDilutedSharesOutstanding 47,989,039us-gaap_WeightedAverageNumberOfDilutedSharesOutstanding 44,988,704us-gaap_WeightedAverageNumberOfDilutedSharesOutstanding 39,038,883us-gaap_WeightedAverageNumberOfDilutedSharesOutstanding 59,408,252us-gaap_WeightedAverageNumberOfDilutedSharesOutstanding 46,087,773us-gaap_WeightedAverageNumberOfDilutedSharesOutstanding 34,127,312us-gaap_WeightedAverageNumberOfDilutedSharesOutstanding