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Income Taxes (Details 2) (USD $)
Dec. 31, 2014
Dec. 31, 2013
Deferred tax assets:    
Capitalized research expense $ 2,059,000us-gaap_DeferredTaxAssetsInProcessResearchAndDevelopment $ 2,782,000us-gaap_DeferredTaxAssetsInProcessResearchAndDevelopment
Net operating loss carryforwards 64,354,000us-gaap_DeferredTaxAssetsOperatingLossCarryforwards 48,846,000us-gaap_DeferredTaxAssetsOperatingLossCarryforwards
Research and development and other tax credits 2,417,000us-gaap_DeferredTaxAssetsOtherTaxCarryforwards 1,877,000us-gaap_DeferredTaxAssetsOtherTaxCarryforwards
Other 8,491,000us-gaap_DeferredTaxAssetsOther 8,641,000us-gaap_DeferredTaxAssetsOther
Deferred Tax Assets, Gross 77,321,000us-gaap_DeferredTaxAssetsGross 62,146,000us-gaap_DeferredTaxAssetsGross
Valuation allowance (75,363,000)us-gaap_DeferredTaxAssetsValuationAllowance (61,061,000)us-gaap_DeferredTaxAssetsValuationAllowance
Total deferred tax assets 1,958,000us-gaap_DeferredTaxAssetsNet 1,085,000us-gaap_DeferredTaxAssetsNet
Deferred tax liabilities:    
Acquired intangibles (804,000)us-gaap_DeferredTaxLiabilitiesGoodwillAndIntangibleAssetsIntangibleAssets (1,096,000)us-gaap_DeferredTaxLiabilitiesGoodwillAndIntangibleAssetsIntangibleAssets
Investment in affiliated entity (1,315,000)us-gaap_DeferredTaxLiabilitiesInvestmentInNoncontrolledAffiliates (123,000)us-gaap_DeferredTaxLiabilitiesInvestmentInNoncontrolledAffiliates
Net deferred tax liabilities $ (161,000)us-gaap_DeferredTaxLiabilities $ (134,000)us-gaap_DeferredTaxLiabilities