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Summary of Significant Accounting Policies (Tables)
 12 Months Ended
Dec. 31, 2015
Accounting Policies [Abstract]  
Schedule of Earnings Per Share, Basic and Diluted
The following tables reconcile the components of the numerator and denominator included in the calculations of diluted loss per share:
 
Year Ended December 31,
 
2015
 
2014
 
2013
Numerator
 
 
 
 
 
Net loss attributable to Inovio Pharmaceuticals, Inc.
$
(29,187,606
)
 
$
(36,121,713
)
 
$
(66,028,448
)
Reflect adjustment for decrease in fair value of warrant liability
(721,591
)
 
(2,181,203
)
 
—

Numerator for use in diluted loss per share
$
(29,909,197
)
 
$
(38,302,916
)
 
$
(66,028,448
)
 
 
 
 
 
 
Denominator
 
 
 
 
 
Weighted average number of common shares outstanding
68,198,142

 
59,127,349

 
46,087,773

Effect of dilutive potential common shares from warrants
167,123

 
280,903

 
—

Denominator for use in diluted loss per share
68,365,265

 
59,408,252

 
46,087,773

 
 
 
 
 
 
Net loss per share, diluted
$
(0.44
)
 
$
(0.64
)
 
$
(1.43
)
Summary of common shares that were excluded from the diluted net loss per share calculation because of their anti-dilutive effect
The following table summarizes potential common shares that were excluded from diluted net loss per share calculation because of their anti-dilutive effect:
 
 
Year Ended December 31,
 
2015
 
2014
 
2013
Options to purchase common stock
5,862,364

 
4,840,514

 
4,134,530

Warrants to purchase common stock
276,813

 
727,969

 
3,514,815

Restricted stock units
230,000

 
—

 
—

Convertible preferred stock
8,456

 
8,456

 
9,559

Total
6,377,633

 
5,576,939

 
7,658,904
Summary of assumptions used to estimate the fair value of stock options
Weighted average assumptions used in the Black-Scholes model for employees and directors are presented below:
 
 
Year Ended December 31,
 
2015
 
2014
 
2013
Risk-free interest rate
0.99%
 
1.47%
 
0.41%
Expected volatility
74%
 
109%
 
111%
Expected life in years
5
 
5
 
4
Dividend yield
—
 
—
 
—
Forfeiture rate
7%
 
8%
 
8%

Assumptions used in the Black-Scholes model for non-employees are presented below:
 
 
Year Ended December 31,
 
2015
 
2014
 
2013
Risk-free interest rate
2.14%-2.31%
 
1.52%-2.73%
 
0.84% – 1.52%
Expected volatility
105%-108%
 
104%-115%
 
102%-113%
Expected life in years
7-10
 
7-10
 
7-10
Dividend yield
—
 
—
 
—