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Summary of Significant Accounting Policies - Net Loss Per Share Table (Details) - USD ($)
3 Months Ended 12 Months Ended
Dec. 31, 2015
Sep. 30, 2015
Jun. 30, 2015
Mar. 31, 2015
Dec. 31, 2014
Sep. 30, 2014
Jun. 30, 2014
Mar. 31, 2014
Dec. 31, 2015
Dec. 31, 2014
Dec. 31, 2013
Numerator [Abstract]                      
Net loss attributable to Inovio Pharmaceuticals, Inc. $ (17,952,045) $ 5,594,468 $ (6,248,250) $ (10,581,779) $ (7,411,404) $ (7,177,575) $ (10,711,274) $ (10,821,460) $ (29,187,606) $ (36,121,713) $ (66,028,448)
Reflect adjustment for decrease in fair value of warrant liability                 (721,591) (2,181,203) 0
Numerator for use in diluted loss per share                 $ (29,909,197) $ (38,302,916) $ (66,028,448)
Denominator [Abstract]                      
Weighted average number of common shares outstanding (shares) 72,194,504 72,029,644 67,655,975 60,741,082 60,610,367 60,392,911 60,232,498 55,159,002 68,198,142 59,127,349 46,087,773
Effect of dilutive potential common shares from warrants (shares)                 167,123 280,903 0
Denominator for use in diluted loss per share (shares) 72,194,504 73,961,237 67,838,738 60,913,423 60,805,871 60,602,831 60,474,859 55,159,002 68,365,265 59,408,252 46,087,773
Net loss per share, Diluted ($ per share) $ (0.25) $ 0.07 $ (0.09) $ (0.18) $ (0.12) $ (0.12) $ (0.19) $ (0.20) $ (0.44) $ (0.64) $ (1.43)