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Goodwill and Intangible Assets (Details) - USD ($)
 12 Months Ended
Dec. 31, 2015
Dec. 31, 2014
Jun. 30, 2009
Jan. 31, 2005
Non-Amortizing:        
Goodwill, Gross $ 10,113,371 $ 10,113,371    
Goodwill, Net Book Value 10,113,371 10,113,371    
Amortizing:        
Intangible assets, Gross 19,617,873 19,617,873    
Intangible assets, Accumulated Amortization (15,712,013) (14,841,814)    
Intangible assets, Net Book Value 3,905,860 4,776,059    
Total goodwill and intangible assets, Gross 29,731,244 29,731,244    
Total goodwill and intangible assets, Net Book Value $ 14,019,231 14,889,430    
Inovio AS        
Non-Amortizing:        
Goodwill, Net Book Value       $ 3,900,000
VGX        
Non-Amortizing:        
Goodwill, Net Book Value     $ 6,200,000  
Minimum        
Schedule of intangible assets by major asset class        
Useful Life (Yrs) 5 years      
Maximum        
Schedule of intangible assets by major asset class        
Useful Life (Yrs) 18 years      
Patents        
Amortizing:        
Intangible assets, Gross $ 5,802,528 5,802,528    
Intangible assets, Accumulated Amortization (5,516,122) (5,358,433)    
Intangible assets, Net Book Value $ 286,406 444,095    
Patents | Minimum        
Schedule of intangible assets by major asset class        
Useful Life (Yrs) 8 years      
Patents | Maximum        
Schedule of intangible assets by major asset class        
Useful Life (Yrs) 17 years      
Licenses        
Amortizing:        
Intangible assets, Gross $ 1,323,761 1,323,761    
Intangible assets, Accumulated Amortization (1,133,113) (1,104,366)    
Intangible assets, Net Book Value $ 190,648 219,395    
Licenses | Minimum        
Schedule of intangible assets by major asset class        
Useful Life (Yrs) 8 years      
Licenses | Maximum        
Schedule of intangible assets by major asset class        
Useful Life (Yrs) 17 years      
CELLECTRA        
Amortizing:        
Intangible assets, Gross $ 8,106,270 8,106,270    
Intangible assets, Accumulated Amortization (6,397,947) (5,970,866)    
Intangible assets, Net Book Value $ 1,708,323 2,135,404    
CELLECTRA | Minimum        
Schedule of intangible assets by major asset class        
Useful Life (Yrs) 5 years      
CELLECTRA | Maximum        
Schedule of intangible assets by major asset class        
Useful Life (Yrs) 11 years      
GHRH        
Schedule of intangible assets by major asset class        
Useful Life (Yrs) 11 years      
Amortizing:        
Intangible assets, Gross $ 335,314 335,314    
Intangible assets, Accumulated Amortization (208,581) (176,899)    
Intangible assets, Net Book Value $ 126,733 158,415    
Other        
Schedule of intangible assets by major asset class        
Useful Life (Yrs) 18 years      
Amortizing:        
Intangible assets, Gross $ 4,050,000 4,050,000    
Intangible assets, Accumulated Amortization (2,456,250) (2,231,250)    
Intangible assets, Net Book Value $ 1,593,750 $ 1,818,750