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Condensed Consolidated Statements of Cash Flows (Unaudited) - USD ($)
 3 Months Ended
Mar. 31, 2016
Mar. 31, 2015
Cash flows from operating activities:    
Net loss $ (8,042,820) $ (10,582,871)
Adjustments to reconcile net loss to net cash used in operating activities:    
Depreciation 387,867 213,994
Amortization of intangible assets 209,542 223,485
Change in value of common stock warrants 409,369 1,227
Stock-based compensation 3,057,312 2,411,455
Amortization of premiums on investments 66,057 71,119
Deferred rent 9,769 124,106
Loss on disposal of fixed assets 0 (2,252)
Loss on short-term investments 4,532 1,183
(Gain) Loss on investment in affiliated entity (7,480,977) 2,352,309
Changes in operating assets and liabilities:    
Accounts receivable (3,819,700) (495,377)
Prepaid expenses and other current assets (205,450) 140,309
Prepaid expenses and other current assets from affiliated entity (927,911) (635,090)
Other assets (361,070) (190,652)
Accounts payable and accrued expenses (1,621,449) (1,986,726)
Accrued clinical trial expenses 1,550,313 (740,547)
Accounts payable and accrued expenses due to affiliated entity 42,186 (23,407)
Deferred revenue 1,420,279 (2,838,136)
Deferred revenue from affiliated entity (437,827) (112,499)
Net cash used in operating activities (15,739,978) (12,068,370)
Cash flows from investing activities:    
Purchases of investments (12,162,941) (4,989,030)
Maturities of investments 12,505,928 3,186,000
Purchases of capital assets (681,141) (526,859)
Net cash used in investing activities (338,154) (2,329,889)
Cash flows from financing activities:    
Proceeds from stock option and warrant exercises 69,484 0
Net cash provided by financing activities 69,484 0
Decrease in cash and cash equivalents (16,008,648) (14,398,259)
Cash and cash equivalents, beginning of period 57,632,693 40,543,982
Cash and cash equivalents, end of period 41,624,045 26,145,723
Supplemental disclosure of non-cash activities    
Amounts accrued for purchases of property and equipment 658,853 48,630
Lease incentive recorded as fixed assets and deferred rent $ 134,500 $ 0