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Stockholders' Equity (Tables)
12 Months Ended
Dec. 31, 2016
Stockholders' Equity Note [Abstract]  
Summary of preferred stock authorized, issued and outstanding
 
 
 
 
 
Outstanding as of
December 31,
 
Authorized
 
Issued
 
2016
 
2015
Series C Preferred Stock, par $0.001
1,091

 
1,091

 
23

 
23

Summary of warrants outstanding
The following table summarizes the warrants outstanding as of December 31, 2016 and 2015:
 
 
 
 
 
 
 
As of December 31, 2016
 
As of December 31, 2015
Issued in Connection With:
 
Exercise
Price
 
Expiration
Date
 
Number of
Warrants
 
Common Stock
Warrant Liability
 
Number of
Warrants
 
Common Stock
Warrant Liability
March 2013 financing
 
$
3.17

 
September 12, 2018
 
284,091

 
$
1,167,614

 
284,091

 
$
1,301,138

Warrants assumed in June 2009 Merger
 
$ 4.08 - 5.12

 
April 28, 2016
 

 

 
276,813

 

Total
 
 
 
 
 
284,091

 
$
1,167,614

 
560,904

 
$
1,301,138

Schedule of shares authorized under stock option plans, by exercise price range
The following table summarizes total stock options outstanding at December 31, 2016:
 
 
 
Options Outstanding
 
Options Exercisable
Exercise Price
 
Options
Outstanding
 
Weighted-Average
Remaining
Contractual Life
(in Years)
 
Weighted
Average
Exercise Price
 
Options
Exercisable
 
Weighted-Average
Exercise Price
$0.00-$3.00
 
1,184,058

 
5.6
 
$
2.25

 
1,184,058

 
$
2.25

$3.01-$6.00
 
1,063,941

 
2.1
 
$
4.76

 
1,055,351

 
$
4.75

$6.01-$9.00
 
3,337,860

 
7.7
 
$
7.25

 
1,668,725

 
$
7.23

$9.01-$12.00
 
418,612

 
8.6
 
$
9.75

 
155,420

 
$
9.92

$12.01-$15.00
 
801,712

 
6.4
 
$
12.94

 
626,277

 
$
12.93

 
 
6,806,183

 
6.3
 
$
6.81

 
4,689,831

 
$
6.26

Schedule of stock options, activity
Stock option activity under our equity incentive plans was as follows: 
 
Number of
Shares
 
Weighted-Average
Exercise Price
Balance, December 31, 2015
5,862,364

 
$
6.46

Granted
1,705,169

 
7.47

Exercised
(631,065
)
 
4.96

Cancelled
(130,285
)
 
8.66

Balance, December 31, 2016
6,806,183

 
$
6.81

Schedule of Share-based Compensation, Restricted Stock Units Award Activity
RSU activity under our equity incentive plans was as follows: 
 
Number of
Shares
 
Weighted-Average
Exercise Price
Balance, December 31, 2015
230,000

 
$

Granted
671,500

 

Vested
(96,666
)
 

Cancelled
(6,000
)
 

Balance, December 31, 2016
798,834

 
$