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Summary of Significant Accounting Policies - Net Loss Per Share Table (Details) - USD ($)
3 Months Ended 12 Months Ended
Dec. 31, 2016
Sep. 30, 2016
Jun. 30, 2016
Mar. 31, 2016
Dec. 31, 2015
Sep. 30, 2015
Jun. 30, 2015
Mar. 31, 2015
Dec. 31, 2016
Dec. 31, 2015
Dec. 31, 2014
Numerator [Abstract]                      
Net loss attributable to Inovio Pharmaceuticals, Inc.         $ (17,952,045) $ 5,594,468 $ (6,248,250) $ (10,581,779) $ (73,740,339) $ (29,187,606) $ (36,121,713)
Reflect adjustment for decrease in fair value of warrant liability                 0 (721,591) (2,181,203)
Numerator for use in diluted loss per share                 $ (73,740,339) $ (29,909,197) $ (38,302,916)
Denominator [Abstract]                      
Weighted average number of common shares outstanding (shares)                 73,214,766 68,198,142 59,127,349
Effect of dilutive potential common shares from warrants (shares)                 0 167,123 280,903
Denominator for use in diluted loss per share (shares)                 73,214,766 68,365,265 59,408,252
Net loss per share, Diluted ($ per share) $ (0.36) $ (0.28) $ (0.26) $ (0.11) $ (0.25) $ 0.07 $ (0.09) $ (0.18) $ (1.01) $ (0.44) $ (0.64)