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Summary of Significant Accounting Policies (Tables)
 12 Months Ended
Dec. 31, 2016
Accounting Policies [Abstract]  
Schedule of Earnings Per Share, Basic and Diluted
The following tables reconcile the components of the numerator and denominator included in the calculations of diluted loss per share:
 
Year Ended December 31,
 
2016
 
2015
 
2014
Numerator
 
 
 
 
 
Net loss attributable to Inovio Pharmaceuticals, Inc.
$
(73,740,339
)
 
$
(29,187,606
)
 
$
(36,121,713
)
Reflect adjustment for decrease in fair value of warrant liability
—

 
(721,591
)
 
(2,181,203
)
Numerator for use in diluted loss per share
$
(73,740,339
)
 
$
(29,909,197
)
 
$
(38,302,916
)
 
 
 
 
 
 
Denominator
 
 
 
 
 
Weighted average number of common shares outstanding
73,214,766

 
68,198,142

 
59,127,349

Effect of dilutive potential common shares from warrants
—

 
167,123

 
280,903

Denominator for use in diluted loss per share
73,214,766

 
68,365,265

 
59,408,252

 
 
 
 
 
 
Net loss per share, diluted
$
(1.01
)
 
$
(0.44
)
 
$
(0.64
)
Summary of common shares that were excluded from the diluted net loss per share calculation because of their anti-dilutive effect
The following table summarizes potential common shares that were excluded from diluted net loss per share calculation because of their anti-dilutive effect:
 
 
Year Ended December 31,
 
2016
 
2015
 
2014
Options to purchase common stock
6,806,183

 
5,862,364

 
4,840,514

Warrants to purchase common stock
284,091

 
276,813

 
727,969

Restricted stock units
798,834

 
230,000

 
—

Convertible preferred stock
8,456

 
8,456

 
8,456

Total
7,897,564

 
6,377,633

 
5,576,939
Summary of assumptions used to estimate the fair value of stock options
Weighted average assumptions used in the Black-Scholes model for employees are presented below:
 
 
Year Ended December 31,
 
2016
 
2015
 
2014
Risk-free interest rate
0.91%
 
0.99%
 
1.47%
Expected volatility
76%
 
74%
 
109%
Expected life in years
5
 
5
 
5
Dividend yield
—
 
—
 
—
Forfeiture rate
7%
 
7%
 
8%

Assumptions used in the Black-Scholes model for non-employees are presented below:
 
 
Year Ended December 31,
 
2016
 
2015
 
2014
Risk-free interest rate
2.3%-2.5%
 
2.1%-2.3%
 
1.5%-2.7%
Expected volatility
71%-104%
 
105%-108%
 
104%-115%
Expected life in years
7-10
 
7-10
 
7-10
Dividend yield
—
 
—
 
—