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Goodwill and Intangible Assets (Details) - USD ($)
 12 Months Ended
Dec. 31, 2016
Apr. 30, 2016
Dec. 31, 2015
Jun. 30, 2009
Jan. 31, 2005
Indefinite lived:          
Goodwill, Gross $ 10,513,371   $ 10,113,371    
Goodwill 10,513,371   10,113,371    
Definite lived:          
Intangible assets, Gross 24,717,873   19,617,873    
Intangible assets, Accumulated Amortization (17,089,479)   (15,712,013)    
Intangible assets, Net Book Value 7,628,394   3,905,860    
Total goodwill and intangible assets, Gross 35,231,244   29,731,244    
Total goodwill and intangible assets, Net Book Value $ 18,141,765   14,019,231    
Inovio AS          
Indefinite lived:          
Goodwill         $ 3,900,000
VGX          
Indefinite lived:          
Goodwill       $ 6,200,000  
Bioject          
Indefinite lived:          
Goodwill   $ 400,000      
Minimum          
Schedule of intangible assets by major asset class          
Useful Life (Yrs) 5 years        
Maximum          
Schedule of intangible assets by major asset class          
Useful Life (Yrs) 18 years        
Patents          
Definite lived:          
Intangible assets, Gross $ 5,802,528   5,802,528    
Intangible assets, Accumulated Amortization (5,618,854)   (5,516,122)    
Intangible assets, Net Book Value $ 183,674   286,406    
Patents | Minimum          
Schedule of intangible assets by major asset class          
Useful Life (Yrs) 8 years        
Patents | Maximum          
Schedule of intangible assets by major asset class          
Useful Life (Yrs) 17 years        
Licenses          
Definite lived:          
Intangible assets, Gross $ 1,323,761   1,323,761    
Intangible assets, Accumulated Amortization (1,161,861)   (1,133,113)    
Intangible assets, Net Book Value $ 161,900   190,648    
Licenses | Minimum          
Schedule of intangible assets by major asset class          
Useful Life (Yrs) 8 years        
Licenses | Maximum          
Schedule of intangible assets by major asset class          
Useful Life (Yrs) 17 years        
CELLECTRA          
Definite lived:          
Intangible assets, Gross $ 8,106,270   8,106,270    
Intangible assets, Accumulated Amortization (6,825,028)   (6,397,947)    
Intangible assets, Net Book Value $ 1,281,242   1,708,323    
CELLECTRA | Minimum          
Schedule of intangible assets by major asset class          
Useful Life (Yrs) 5 years        
CELLECTRA | Maximum          
Schedule of intangible assets by major asset class          
Useful Life (Yrs) 11 years        
GHRH          
Schedule of intangible assets by major asset class          
Useful Life (Yrs) 11 years        
Definite lived:          
Intangible assets, Gross $ 335,314   335,314    
Intangible assets, Accumulated Amortization (240,264)   (208,581)    
Intangible assets, Net Book Value 95,050   126,733    
Bioject          
Definite lived:          
Intangible assets, Gross 5,100,000   0    
Intangible assets, Accumulated Amortization (562,222)   0    
Intangible assets, Net Book Value $ 4,537,778   0    
Bioject | Minimum          
Schedule of intangible assets by major asset class          
Useful Life (Yrs) 2 years        
Bioject | Maximum          
Schedule of intangible assets by major asset class          
Useful Life (Yrs) 15 years        
Other          
Schedule of intangible assets by major asset class          
Useful Life (Yrs) 18 years        
Definite lived:          
Intangible assets, Gross $ 4,050,000   4,050,000    
Intangible assets, Accumulated Amortization (2,681,250)   (2,456,250)    
Intangible assets, Net Book Value $ 1,368,750   $ 1,593,750