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Condensed Consolidated Statements of Comprehensive Loss - USD ($) | 3 Months Ended | 6 Months Ended
--- | --- | ---
Jun. 30, 2017 | Jun. 30, 2016 | Jun. 30, 2017 | Jun. 30, 2016
Statement of Comprehensive Income [Abstract] |  |  |  |
Net loss | $ (9,479,116) | $ (18,704,711) | $ (32,565,023) | $ (26,747,531)
Other comprehensive income (loss): |  |  |  |
Unrealized gain (loss) on investment in affiliated entity | 312,253 | 282,572 | (437,708) | 263,575
Unrealized gain on short-term investments | 86,862 | 322,767 | 290,402 | 542,448
Comprehensive loss attributable to Inovio Pharmaceuticals, Inc. | $ (9,080,001) | $ (18,099,372) | $ (32,712,329) | $ (25,941,508)

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