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v3.7.0.1

Condensed Consolidated Statements of Cash Flows - USD ($) | 3 Months Ended | 6 Months Ended | 13 Months Ended
--- | --- | --- | ---
Jun. 30, 2017 | Jun. 30, 2016 | Jun. 30, 2017 | Jun. 30, 2016 | Jun. 30, 2017
Cash flows from operating activities: |  |  |  |  |
Net loss | $ (9,479,116) | $ (18,704,711) | $ (32,565,023) | $ (26,747,531) |
Adjustments to reconcile net loss to net cash used in operating activities: |  |  |  |  |
Depreciation |  |  | 1,020,679 | 827,327 |
Amortization of intangible assets | 404,000 | 347,000 | 810,539 | 556,554 |
Change in value of common stock warrants |  |  | 196,023 | 520,025 |
Stock-based compensation |  |  | 7,937,473 | 5,251,166 |
Amortization of premiums on investments |  |  | 140,599 | 139,659 |
Loss on short-term investments |  |  | 67,366 | 0 |
Deferred rent |  |  | 1,869,341 | (31,783) |
Loss (gain) on investment in affiliated entity | (169,096) | 705,527 | 1,439,721 | (6,775,450) |
Gain on sale of intangible assets |  |  | 0 | (1,000,000) |
Changes in operating assets and liabilities: |  |  |  |  |
Accounts receivable |  |  | 8,298,963 | (3,032,891) |
Accounts receivable from affiliated entity |  |  | (440,945) | 0 |
Prepaid expenses and other current assets |  |  | (3,165,705) | (270,785) |
Prepaid expenses and other current assets from affiliated entity |  |  | 260,694 | (1,271,605) |
Other assets |  |  | 438,896 | (655,334) |
Accounts payable and accrued expenses |  |  | (4,305,114) | (247,009) |
Accrued clinical trial expenses |  |  | 820,362 | 2,405,804 |
Accounts payable and accrued expenses due to affiliated entity |  |  | (225,158) | 435,922 |
Deferred revenue |  |  | (14,325,900) | 1,323,827 |
Deferred revenue from affiliated entity |  |  | (219,792) | (437,827) |
Net cash used in operating activities |  |  | (31,946,981) | (29,009,931) |
Cash flows from investing activities: |  |  |  |  |
Purchases of investments |  |  | (14,600,112) | (27,985,410) |
Maturities of investments |  |  | 32,173,342 | 27,662,695 |
Purchases of capital assets |  |  | (5,828,137) | (2,196,896) |
Proceeds from sale of intangible assets |  |  | 0 | 1,000,000 |
Purchase of intangible assets and other assets |  |  | 0 | (1,200,000) |
Net cash provided by (used in) investing activities |  |  | 11,745,093 | (2,719,611) |
Cash flows from financing activities: |  |  |  |  |
Proceeds from issuance of common stock, net of issuance costs |  |  | 24,060,196 | 1,301,435 | $ 30,400,000
Proceeds from stock option and warrant exercises, net of tax payments |  |  | 865,857 | 1,395,346 |
Expenses from other financing activities |  |  | 0 | (149,559) |
Net cash provided by financing activities |  |  | 24,926,053 | 2,547,222 |
Increase (decrease) in cash and cash equivalents |  |  | 4,724,165 | (29,182,320) |
Cash and cash equivalents, beginning of period |  |  | 19,136,472 | 57,632,693 |
Cash and cash equivalents, end of period | 23,860,637 | 28,450,373 | 23,860,637 | 28,450,373 | 23,860,637
Supplemental disclosure of non-cash activities |  |  |  |  |
Common stock issued for purchase of intangible and other assets of Bioject |  |  | 0 | 4,300,000 |
Change in amounts accrued for purchases of property and equipment |  |  | 1,185,087 | (110,136) |
Lease incentive recorded as fixed assets and deferred rent | $ 0 | $ 134,500 | $ 0 | $ 134,500 | $ 0

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- Definition Amount of cash outflow to a noncontrolling interest. Includes, but not limited to, reduction of noncontrolling interest ownership. Excludes dividends paid to the noncontrolling interest. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 230 -SubTopic 10 -Section 45 -Paragraph 15 -URI http://asc.fasb.org/extlink&oid=98514028&loc=d3e3291-108585 + Details
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- Definition The cash inflow from the additional capital contribution to the entity. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 230 -SubTopic 10 -Section 45 -Paragraph 14 -Subparagraph (a) -URI http://asc.fasb.org/extlink&oid=98514028&loc=d3e3255-108585 + Details
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- Definition The cash inflow from disposal of asset without physical form usually arising from contractual or other legal rights, excluding goodwill. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 230 -SubTopic 10 -Section 45 -Paragraph 12 -Subparagraph (c) -URI http://asc.fasb.org/extlink&oid=98514028&loc=d3e3179-108585 + Details
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- Definition The cash inflow from sales of all investments, including securities and other assets, having ready marketability and intended by management to be liquidated, if necessary, within the current operating cycle. Includes cash flows from securities classified as trading securities that were acquired for reasons other than sale in the short-term. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 230 -SubTopic 10 -Section 45 -Paragraph 12 -URI http://asc.fasb.org/extlink&oid=98514028&loc=d3e3179-108585 + Details
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- Definition Amount of cash inflow from exercise of stock options granted under share-based compensation arrangement. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 230 -SubTopic 10 -Section 45 -Paragraph 14 -Subparagraph (a) -URI http://asc.fasb.org/extlink&oid=98514028&loc=d3e3255-108585 Reference 2: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 2A -Subparagraph (a) -URI http://asc.fasb.org/extlink&oid=96867065&loc=SL79508275-113901 + Details
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- Definition The consolidated profit or loss for the period, net of income taxes, including the portion attributable to the noncontrolling interest. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 810 -SubTopic 10 -Section 55 -Paragraph 4K -URI http://asc.fasb.org/extlink&oid=84234705&loc=SL4591552-111686 Reference 2: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 810 -SubTopic 10 -Section 45 -Paragraph 19 -URI http://asc.fasb.org/extlink&oid=96868048&loc=SL4569616-111683 Reference 3: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 810 -SubTopic 10 -Section 50 -Paragraph 1A -Subparagraph (c)(1) -URI http://asc.fasb.org/extlink&oid=84161450&loc=SL4573702-111684 Reference 4: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 810 -SubTopic 10 -Section 55 -Paragraph 4J -URI http://asc.fasb.org/extlink&oid=84234705&loc=SL4591551-111686 Reference 5: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 810 -SubTopic 10 -Section 50 -Paragraph 1A -Subparagraph (a)(2) -URI http://asc.fasb.org/extlink&oid=84161450&loc=SL4573702-111684 + Details
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- Definition The aggregate amount of noncash, equity-based employee remuneration. This may include the value of stock or unit options, amortization of restricted stock or units, and adjustment for officers' compensation. As noncash, this element is an add back when calculating net cash generated by operating activities using the indirect method. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 230 -SubTopic 10 -Section 45 -Paragraph 28 -Subparagraph (a) -URI http://asc.fasb.org/extlink&oid=98514028&loc=d3e3602-108585 + Details
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- Definition Difference between actual rental income due and rental income recognized on a straight-line basis. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 230 -SubTopic 10 -Section 45 -Paragraph 28 -Subparagraph (a) -URI http://asc.fasb.org/extlink&oid=98514028&loc=d3e3602-108585 + Details
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