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Summary of Significant Accounting Policies - Antidilutive Securities Table (Details) - shares | 12 Months Ended
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Dec. 31, 2017 | Dec. 31, 2016 | Dec. 31, 2015
Summary of common shares that were excluded from the diluted net loss per share calculation because of their anti-dilutive effect |  |  |
Total antidilutive securities (shares) | 8,937,494 | 7,897,564 | 6,377,633
Options to purchase common stock |  |  |
Summary of common shares that were excluded from the diluted net loss per share calculation because of their anti-dilutive effect |  |  |
Total antidilutive securities (shares) | 7,694,870 | 6,806,183 | 5,862,364
Warrants to purchase common stock |  |  |
Summary of common shares that were excluded from the diluted net loss per share calculation because of their anti-dilutive effect |  |  |
Total antidilutive securities (shares) | 0 | 284,091 | 276,813
Restricted stock units |  |  |
Summary of common shares that were excluded from the diluted net loss per share calculation because of their anti-dilutive effect |  |  |
Total antidilutive securities (shares) | 1,234,168 | 798,834 | 230,000
Convertible preferred stock |  |  |
Summary of common shares that were excluded from the diluted net loss per share calculation because of their anti-dilutive effect |  |  |
Total antidilutive securities (shares) | 8,456 | 8,456 | 8,456

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- Definition Common stock equivalents. + References No definition available. + Details
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- Definition Securities (including those issuable pursuant to contingent stock agreements) that could potentially dilute basic earnings per share (EPS) or earnings per unit (EPU) in the future that were not included in the computation of diluted EPS or EPU because to do so would increase EPS or EPU amounts or decrease loss per share or unit amounts for the period presented. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 260 -SubTopic 10 -Section 50 -Paragraph 1 -Subparagraph (c) -URI http://asc.fasb.org/extlink&oid=6371337&loc=d3e3550-109257 + Details
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