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Stockholders' Equity (Tables)
12 Months Ended
Dec. 31, 2017
Stockholders' Equity Note [Abstract]  
Summary of preferred stock authorized, issued and outstanding
 
 
 
 
 
Shares Outstanding as of
December 31,
 
Shares Authorized
 
Shares Issued
 
2017
 
2016
Series C Preferred Stock, par $0.001
1,091

 
1,091

 
23

 
23

Summary of warrants outstanding
The following table summarizes the warrants outstanding as of December 31, 2017 and 2016:
 
 
 
 
 
 
 
As of December 31, 2017
 
As of December 31, 2016
Issued in Connection With:
 
Exercise
Price
 
Expiration
Date
 
Number of
Warrants
 
Common Stock
Warrant Liability
 
Number of
Warrants
 
Common Stock
Warrant Liability
March 2013 financing
 
$
3.17

 
September 12, 2018
 
284,091

 
$
360,795

 
284,091

 
$
1,167,614

Total
 
 
 
 
 
284,091

 
$
360,795

 
284,091

 
$
1,167,614

Schedule of shares authorized under stock option plans, by exercise price range
The following table summarizes total stock options outstanding at December 31, 2017:
 
 
 
Options Outstanding
 
Options Exercisable
Exercise Price
 
Shares Underlying Options
Outstanding
 
Weighted-Average
Remaining
Contractual Life
(in Years)
 
Weighted
Average
Exercise Price
 
Shares Underlying Options
Exercisable
 
Weighted Average
Exercise Price
$1.48-$3.00
 
1,177,183

 
4.6
 
$
2.25

 
1,177,183

 
$
2.25

$3.01-$6.00
 
753,932

 
3.4
 
$
4.64

 
668,244

 
$
4.57

$6.01-$9.00
 
4,709,442

 
7.6
 
$
7.09

 
2,639,454

 
$
7.23

$9.01-$12.00
 
357,603

 
8.0
 
$
9.79

 
263,180

 
$
9.83

$12.01-$15.00
 
696,710

 
6.2
 
$
12.96

 
696,710

 
$
12.96

 
 
7,694,870

 
6.6
 
$
6.77

 
5,444,771

 
$
6.68

Schedule of stock options, activity
Stock option activity under the Company’s equity incentive plans during the year ended December 31, 2017 was as follows:
 
Number of
Shares
 
Weighted-Average
Exercise Price
Balance, December 31, 2016
6,806,183

 
$
6.81

Granted
1,788,121

 
6.62

Exercised
(452,973
)
 
5.18

Cancelled
(446,461
)
 
8.49

Balance, December 31, 2017
7,694,870

 
$
6.77

Schedule of Share-based Compensation, Restricted Stock Units Award Activity
RSU activity under the Company’s equity incentive plans during the year ended December 31, 2017 was as follows:
 
Number of
Shares
 
Weighted-Average
Exercise Price
Balance, December 31, 2016
798,834

 
$

Granted
1,035,443

 

Vested
(561,462
)
 

Cancelled
(38,647
)
 

Balance, December 31, 2017
1,234,168

 
$