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Summary of Significant Accounting Policies - Calculation of Net Loss Per Share (Details) - USD ($)	3 Months Ended								12 Months Ended
	Dec. 31, 2017	Sep. 30, 2017	Jun. 30, 2017	Mar. 31, 2017	Dec. 31, 2016	Sep. 30, 2016	Jun. 30, 2016	Mar. 31, 2016	Dec. 31, 2017	Dec. 31, 2016	Dec. 31, 2015
Numerator [Abstract]
Net loss attributable to Inovio Pharmaceuticals, Inc.	$ (21,506,179)	$ (34,134,570)	$ (9,479,116)	$ (23,085,907)	$ (26,233,470)	$ (20,759,338)	$ (18,704,711)	$ (8,042,820)	$ (88,205,772)	$ (73,740,339)	$ (29,187,606)
Adjustment for decrease in fair value of warrant liability									(806,819)	0	(721,591)
Numerator for use in diluted net loss per share									$ (89,012,591)	$ (73,740,339)	$ (29,909,197)
Denominator [Abstract]
Weighted average number of common shares outstanding (shares)									81,777,493	73,214,766	68,198,142
Effect of dilutive potential common shares from warrants (shares)									140,529	0	167,123
Denominator for use in diluted loss per share (shares)									81,918,022	73,214,766	68,365,265
Net loss per share, Diluted ($ per share)	$ (0.24)	$ (0.40)	$ (0.13)	$ (0.31)	$ (0.36)	$ (0.28)	$ (0.26)	$ (0.11)	$ (1.09)	$ (1.01)	$ (0.44)

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The amount of net income (loss) for the period available to each share of common stock or common unit outstanding during the reporting period and to each share or unit that would have been outstanding assuming the issuance of common shares or units for all dilutive potential common shares or units outstanding during the reporting period.

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Additional shares included in the calculation of diluted EPS as a result of the potentially dilutive effect of call options and warrants using the treasury stock method.

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