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Consolidated Statements of Comprehensive Loss - USD ($)
12 Months Ended
Dec. 31, 2017
Dec. 31, 2016
Dec. 31, 2015
Statement of Comprehensive Income [Abstract]      
Net loss $ (88,205,772) $ (73,740,339) $ (29,102,837)
Other comprehensive income (loss):      
Unrealized gain (loss) on investment in affiliated entity, net of tax (1,452,431) (1,268,404) 2,952,201
Unrealized gain (loss) on short-term investments, net of tax 7,458 (111,967) 7,528
Comprehensive loss (89,650,745) (75,120,710) (26,143,108)
Comprehensive income attributable to non-controlling interest 0 0 (84,769)
Comprehensive loss attributable to Inovio Pharmaceuticals, Inc. $ (89,650,745) $ (75,120,710) $ (26,227,877)