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Related Party Transactions (Details) - USD ($)
 1 Months Ended 12 Months Ended
Dec. 31, 2017
Dec. 31, 2016
Mar. 31, 2016
Jan. 31, 2016
May 31, 2015
Dec. 31, 2017
Dec. 31, 2016
Dec. 31, 2015
Dec. 31, 2013
Dec. 31, 2010
May 31, 2016
May 31, 2014
Related Party Transaction [Line Items]                        
Full payment           $ 1,000,000 $ 1,000,000 $ 1,000,000        
Long-term other assets $ 2,639,354 $ 2,113,147       2,639,354 2,113,147          
Ownership percentage by parent                       85.00%
Payment of receivable                     $ 2,000,000  
Future payments to be received         $ 1,000,000              
Ownership                     16.40%  
Payment of cash distribution             1,000,000 1,000,000        
Investment in affiliated entity - PLS 2,325,079 3,777,510       2,325,079 3,777,510          
Parent                        
Related Party Transaction [Line Items]                        
Payment of cash distribution             850,000 850,000        
Minority shareholders                        
Related Party Transaction [Line Items]                        
Payment of cash distribution             150,000 150,000        
Plumbline Life Sciences                        
Related Party Transaction [Line Items]                        
Revenue from related parties           215,000 212,000          
Carrying value of investment                       $ 0
Accounts receivable 370,000 155,000       370,000 155,000          
Available-for-sale Securities                        
Related Party Transaction [Line Items]                        
Number of shares owned (shares)                     395,758  
VGX Pharmaceuticals | Available-for-sale Securities                        
Related Party Transaction [Line Items]                        
Number of shares owned (shares)                     465,364  
GeneOne (affiliated entity)                        
Related Party Transaction [Line Items]                        
Full payment 1,000,000                      
Ownership target       35.00% 35.00%              
Term                 20 years      
Payment received for license granted                   $ 3,000,000    
Deferred revenue from affiliated entity                   $ 3,000,000    
Period over which deferred revenue from affiliated entity will be recognized in years                   8 years    
Revenue from related parties           551,000 1,200,000 450,000        
Operating expenses related to affiliated entity           2,300,000 2,800,000 $ 6,900,000        
Accounts receivable from related parties 0 441,000       0 441,000          
Accounts payable/accrued liability 107,000 379,000       107,000 379,000          
Long-term other assets 331,000 571,000       331,000 571,000          
Director                        
Related Party Transaction [Line Items]                        
Term     5 years                  
Revenue from related parties           2,600,000 341,000          
Operating expenses related to affiliated entity           2,300,000 985,000          
Accounts receivable 117,000 152,000       117,000 152,000          
Expenses to reimburse     $ 3,100,000                  
Proceeds from sub-grant   6,100,000                    
Due to related parties $ 820,000 $ 671,000       $ 820,000 $ 671,000