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Net Loss Per Share (Tables) | 3 Months Ended
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Mar. 31, 2018
Earnings Per Share [Abstract] |
Schedule of Diluted Earnings Per Share | The following tables reconcile the components of the numerator and denominator included in the calculations of diluted net loss per share:
| Three Months Ended March 31,
| 2018 |  | 2017
Numerator |  |  |
Net loss | $ | (32,350,828 | ) |  | $ | (23,085,907 | )
Adjustment for decrease in fair value of warrant liability | — |  |  | (116,477 | )
Numerator for use in diluted net loss per share | $ | (32,350,828 | ) |  | $ | (23,202,384 | )
Denominator |  |  |
Weighted average number of common shares outstanding | 90,451,791 |  |  | 74,152,609 |
Effect of dilutive potential common shares | — |  |  | 148,275 |
Denominator for use in diluted net loss per share | 90,451,791 |  |  | 74,300,884 |
Net loss per share, diluted | $ | (0.36 | ) |  | $ | (0.31 | )
Schedule of Antidilutive Securities Excluded from Computation of Earnings Per Share | The following table summarizes potential shares of common stock that were excluded from the diluted net loss per share calculation because of their anti-dilutive effect for the three months ended March 31, 2018 and 2017:
Common Stock Equivalents | 2018 |  | 2017
Options to purchase common stock | 9,467,477 |  |  | 7,841,669 |
Warrants to purchase common stock | 284,091 |  |  | — |
Restricted stock units | 1,791,886 |  |  | 1,376,893 |
Convertible preferred stock | 8,456 |  |  | 8,456 |
Total | 11,551,910 |  |  | 9,227,018 |

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- Definition Tabular disclosure of securities (including those issuable pursuant to contingent stock agreements) that could potentially dilute basic earnings per share (EPS) in the future that were not included in the computation of diluted EPS because to do so would increase EPS amounts or decrease loss per share amounts for the period presented, by antidilutive securities. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 260 -SubTopic 10 -Section 50 -Paragraph 1 -Subparagraph (c) -URI http://asc.fasb.org/extlink&oid=6371337&loc=d3e3550-109257 + Details
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- Definition Tabular disclosure of the effect of income (loss) on an entity's diluted earnings per share. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 260 -SubTopic 10 -Section 50 -Paragraph 1 -Subparagraph (a) -URI http://asc.fasb.org/extlink&oid=6371337&loc=d3e3550-109257 Reference 2: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 260 -SubTopic 10 -Section 45 -Paragraph 2 -URI http://asc.fasb.org/extlink&oid=96947427&loc=d3e1252-109256 Reference 3: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 260 -SubTopic 10 -Section 45 -Paragraph 5 -URI http://asc.fasb.org/extlink&oid=96947427&loc=d3e1311-109256 Reference 4: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 260 -SubTopic 10 -Section 45 -Paragraph 3 -URI http://asc.fasb.org/extlink&oid=96947427&loc=d3e1278-109256 Reference 5: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 225 -SubTopic 10 -Section S99 -Paragraph 2 -Subparagraph (SX 210.5-03.21) -URI http://asc.fasb.org/extlink&oid=63488584&loc=d3e20235-122688 Reference 6: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 260 -SubTopic 10 -Section 55 -Paragraph 52 -URI http://asc.fasb.org/extlink&oid=96948231&loc=d3e4984-109258 + Details
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