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Net Loss Per Share (Tables)
 3 Months Ended
Mar. 31, 2018
Earnings Per Share [Abstract]  
Schedule of Diluted Earnings Per Share
The following tables reconcile the components of the numerator and denominator included in the calculations of diluted net loss per share:
 
Three Months Ended March 31,
 
2018
 
2017
Numerator
 
 
 
Net loss
$
(32,350,828
)
 
$
(23,085,907
)
Adjustment for decrease in fair value of warrant liability
—

 
(116,477
)
Numerator for use in diluted net loss per share
$
(32,350,828
)
 
$
(23,202,384
)
 
 
 
 
Denominator
 
 
 
Weighted average number of common shares outstanding
90,451,791

 
74,152,609

Effect of dilutive potential common shares
—

 
148,275

Denominator for use in diluted net loss per share
90,451,791

 
74,300,884

 
 
 
 
Net loss per share, diluted
$
(0.36
)
 
$
(0.31
)
Schedule of Antidilutive Securities Excluded from Computation of Earnings Per Share
The following table summarizes potential shares of common stock that were excluded from the diluted net loss per share calculation because of their anti-dilutive effect for the three months ended March 31, 2018 and 2017:
 
 
Common Stock Equivalents
2018
 
2017
Options to purchase common stock
9,467,477

 
7,841,669

Warrants to purchase common stock
284,091

 
—

Restricted stock units
1,791,886

 
1,376,893

Convertible preferred stock
8,456

 
8,456

Total
11,551,910

 
9,227,018