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Impact of Recently Issued Accounting Standards (Tables)

6 Months Ended

Jun. 30, 2018

Accounting Policies [Abstract]

Schedule of New Accounting Pronouncements and Changes in Accounting Principles

The cumulative effect of the changes made to the Company's condensed consolidated balance sheet as of January 1, 2018 for the adoption of ASU No. 2016-01 are included in the table below:

Equity:	Balance at December 31, 2017				Adjustments due to ASU No. 2016-01				Balance at January 1, 2018
Accumulated deficit	$	(523,356,317	)		$	231,366			$	(523,124,951	)
Accumulated other comprehensive loss	$	(117,005	)		$	(231,366	)		$	(348,371	)

The following table illustrates the impact that adopting Topic 606 has had on the Company's reported results in the condensed consolidated statement of operations for the three months ended June 30, 2018.

	Balances Without Adoption of Topic 606 for the Three Months Ended June 30, 2018				Impact of Adopting Topic 606				As Reported for the Three Months Ended June 30, 2018
Revenues:
Revenue under collaborative research and development arrangements	$	24,385,852			$	—			$	24,385,852
Revenue under collaborative research and development arrangements with affiliated entities	60,319				—				60,319
Grants and miscellaneous revenue	1,459,684				(1,457,094		)		2,590
Grants and miscellaneous revenue from affiliated entity	454,820				(454,820		)		—
Total revenues	26,360,675				(1,911,914		)		24,448,761
Operating expenses:
Research and development	24,374,534				(1,911,914		)		22,462,620
General and administrative	7,189,310				—				7,189,310
Total operating expenses	$	31,563,844			$	(1,911,914	)		$	29,651,930

The following table illustrates the impact that adopting Topic 606 has had on the Company's reported results in the condensed consolidated statement of operations for the six months ended June 30, 2018.

	Balances Without Adoption of Topic 606 for the Six Months Ended June 30, 2018				Impact of Adopting Topic 606				As Reported for the Six Months Ended June 30, 2018
Revenues:
Revenue under collaborative research and development arrangements	$	25,674,898			$	—			$	25,674,898
Revenue under collaborative research and development arrangements with affiliated entities	208,327				—				208,327
Grants and miscellaneous revenue	2,016,674				(1,921,494		)		95,180
Grants and miscellaneous revenue from affiliated entity	2,212,571				(2,212,571		)		—
Total revenues	30,112,470				(4,134,065		)		25,978,405
Operating expenses:
Research and development	51,174,436				(4,134,065		)		47,040,371
General and administrative	16,887,325				—				16,887,325
Total operating expenses	$	68,061,761			$	(4,134,065	)		$	63,927,696

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- References

No definition available.

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- Definition

Tabular disclosure of changes in accounting principles, including adoption of new accounting pronouncements, that describes the new methods, amount and effects on financial statement line items.

+ References

Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 250
-SubTopic 10
-Section 50
-Paragraph 1
-URI http://asc.fasb.org/extlink&oid=109234566&loc=d3e22499-107794

Reference 2: http://fasb.org/us-gaap/role/ref/legacyRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 270
-SubTopic 10
-Section 45
-Paragraph 13
-URI http://asc.fasb.org/extlink&oid=109236672&loc=d3e765-108305

Reference 3: http://fasb.org/us-gaap/role/ref/legacyRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 270
-SubTopic 10
-Section S99
-Paragraph 1
-Subparagraph (SX 210.10-01.(b)(6))
-URI http://asc.fasb.org/extlink&oid=27015980&loc=d3e46468-122699

Reference 4: http://fasb.org/us-gaap/role/ref/legacyRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 250
-SubTopic 10
-Section 50
-Paragraph 2
-URI http://asc.fasb.org/extlink&oid=109234566&loc=d3e22580-107794

Reference 5: http://fasb.org/us-gaap/role/ref/legacyRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 270
-SubTopic 10
-Section 45
-Paragraph 12
-URI http://asc.fasb.org/extlink&oid=109236672&loc=d3e725-108305

Reference 6: http://fasb.org/us-gaap/role/ref/legacyRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 250
-SubTopic 10
-Section 50
-Paragraph 3
-URI http://asc.fasb.org/extlink&oid=109234566&loc=d3e22583-107794

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